Latest Jobs

Do you have experience of working in a busy office environment in role assisting various stakeholders? Are you an energetic highly motivated individual with excellent administrative and organisational skills? Can you make a positive contribution to our team?

The role holder will work as part of the Cambridge Stem Cell Institute Administrative team, as the main day-to-day admin contact for all Graduate matters. The role holder will be the first point of contact for general queries from current students and will provide assistance to the Institute Director and PhD Programme Director in all Graduate student matters, to ensure that all Graduate students at the Cambridge Stem Cell Institute have a positive experience. The role holder will co-ordinate the admissions processes and course(s) support systems within the Cambridge Stem Cell Institute (CSCI) in order to provide an efficient admissions experience for prospective students, be a point of contact for current students and organise the course schedule and two annual student events.

This role will be based on the Cambridge Biomedical Campus. We are open to discussing flexible working arrangements. This is a part time role of 21.9 hours per week or 0.6 FTE.

Fixed-term: The funds for this post are available for 2 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a standard Disclosure and Barring Service check.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

The closing date for applications is 6th March with interview date to be confirmed.

Informal enquiries about the post are also welcome via email to Danielle Daft, Research Manager, dmj34@cam.ac.uk

Please quote reference PS45171 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

A post-doctoral position funded by the BBSRC is available in the Division of Cellular and Molecular Pathology working within the laboratory of Dr Paolo D'Avino, to undertake a research project investigating the regulation and function of the midbody by phosphorylation (see D'Avino and Capalbo, 2016, Seminars in Cell and Developmental Biology, 53:57-63; Capalbo et al., 2019, Nature Communications, 10:4513; and Halcrow et al., 2022, Cells, 11:3337).

Candidates should have a PhD and a track record of success in molecular and cellular biology research. Significant experience in human cell culture, molecular biology, and microscopy is required. Experience in CRISPR gene editing and/or proteomics would be an advantage.

The ability to work both independently and as part of a team, coupled with excellent communication, organizational and problem-solving skills is required. Other duties/responsibilities include developing and driving research objectives and writing up work for presentation and publication. For more information about the laboratory please visit: https://www.path.cam.ac.uk/research/cellular-and-molecular-pathology-division/davino-group.

Fixed-term: The funds for this post are available until 30 November 2025 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Applications are welcome from internal candidates who would like to apply for the role on the basis of a secondment from their current role in the University.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

The deadline for applications is 9th March 2025. Interviews will take place in the last two weeks of March.

Informal queries should be directed to Dr Paolo D'Avino, ppd21@cam.ac.uk

General queries should be directed to Ellie Watson, ew649@path.cam.ac.uk

Please quote reference PK44968 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Cambridge Centre for Proteomics core facility is currently looking to recruit a Research Laboratory Technician to perform sample preparation from user samples.

The successful candidate will be required to perform routine proteomics sample preparation (run SDS-PAGE gels, in-gel digestion, solution digestion, protein/peptide estimations, and employ sample clean-up techniques). They will also need to collect and log samples, perform routine health and safety tasks, maintain equipment and order lab consumables. The role-holder will be an integral member of CCP and will need to interact closely with other members of CCP and internal and external users of the service to provide help and guidance with sample preparation.

The role holder will have first degree in biochemistry, biology, chemistry or a related subject.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries are welcomed and should be directed to Dr Mike Deery via: md289@cam.ac.uk

If you have any queries regarding the application process, please contact the Biochemistry HR Team: personnel@bioc.cam.ac.uk

Please quote reference PH45160 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Applications are invited for a 3.5 year PhD studentship based within the MRC Toxicology Unit, University of Cambridge. The student will be working on a collaborative project jointly supervised by Anne E. Willis (MRC Toxicology Unit and Paul O'Mahoney (NIHR Health Protection Research Unit).

Human skin provides a barrier against the external environment and is therefore exposed to a variety of environmental insults. When skin is exposed to ultraviolet (UV) radiation from sunlight, both acute and long-term local responses are stimulated including, inflammation, epidermal hyperplasia, carcinogenesis and keratinocyte cell death. Many of the harmful effects of UV-light on skin have been attributed to DNA damage and the activation of DNA damage signalling pathways. More recently, however, it has become clear that UV-induced RNA damage also plays a major role in the acute response of skin to UV radiation [1,2]. UV-induced lesions within RNA cause stalling of translating ribosomes, which leads to activation of the ribotoxic stress response (RSR) [2, 3]. To date, the RSR has been implicated in acute cell cycle arrest, the inflammatory response, epidermal thickening and keratinocyte cell death [1-3]. However, a more complete understanding of RSR's role in the response of skin to UV, and the mechanisms through which this is achieved, remain to be determined.

There is evidence that many proteins involved in post-transcriptional control of gene expression are phosphorylated in cells exposed to UV-light in an RSR-dependent manner, suggesting that the UV RSR targets post-transcriptional gene expression. Thus, the goals of this project are to determine how post-transcriptional gene expression is influenced by the RSR when skin is exposed to UV-light and what effect these mechanisms have on the fate of skin cells. Cell-wide proteomic techniques will be used to highlight novel post-transcriptional targets of the RSR. The influence of these target proteins on post-transcriptional control will be investigated using RNA sequencing technologies. Finally, the biological impact of these targets will be explored in human primary keratinocytes and human ex-vivo skin cell models.

The overall aim of this project is to provide new insights into the molecular mechanisms and functional consequences of the response of skin to UV-light to help develop an informed approach to UV radiation risk management and health protection.

Applicants should have or shortly expect to obtain a first or good upper second-class degree from a UK university, or an equivalent standard from an overseas university, in a relevant subject such as Biomedical Science. Strong analytical skills, in addition to creativity, curiosity, enthusiasm, and the ability to work in a team are essential.

Full funding is provided by the NIHR Health Protection Research Unit in Radiation Threats and Hazards and the MRC Toxicology Unit. This includes Maintenance and the University Composition Fee (Home Fee rate only) with effect from 1 October 2025.

This studentship is open to UK citizens or overseas students who meet the UK residency requirements (home fees) or who are able to augment the funds to cover the extra costs associated with international student fees. Full details of the University's entrance requirements are specified here: http://www.graduate.study.cam.ac.uk/application-process/entry-requirements.

All formal applications will need to be made through the University Application Portal: https://www.postgraduate.study.cam.ac.uk/courses/directory/bltopdtox

If you have any queries regarding the application process, please contact hradmin@mrc-tox.cam.ac.uk

Further information can be found on our website: https://www.mrc-tox.cam.ac.uk

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Applications are invited for an enthusiastic and motivated Postdoctoral Research scientist to work on a Medical Research Council (MRC) funded project with Dr Erica Watson and Prof William Colledge.

The Watson lab is a developmental biology group based in the Department of Physiology, Development and Neuroscience at the University of Cambridge (https://www.pdn.cam.ac.uk/directory/watson-erica) and is a member of the Loke Centre for Trophoblast Research (https://www.trophoblast.cam.ac.uk). The over-arching goal of this lab is to explore the epigenetic mechanisms behind transgenerational inheritance of developmental and metabolic phenotypes in a genetic mouse model of abnormal folate metabolism. Key research avenues aim to uncover important epigenetic changes in the germ cells that result from abnormal folate metabolism and how these changes influence epigenetic stability, gene transcription, and fetoplacental development in the multiple generations that follow. The Watson lab is an inclusive and welcoming group, committed to mentoring and supporting career development of all members.

The Colledge lab is also based in the Department of Physiology, Development and Neuroscience. Professor Colledge is a reproductive physiologist who is interested in all aspects of mammalian fertility and has considerable experience of using transgenic mice as experimental models.

We are looking for a postdoctoral scientist to investigate sperm non-coding RNA (ncRNA) as a possible mediator of transgenerational inheritance of congenital malformations caused by abnormal folate metabolism. You will be the key person to manage the programme, run the experiments, analyse the data, and write manuscripts for publication.

The successful candidate should have completed (or will be about to complete) their PhD in a relevant field. They should have a background in molecular techniques and mouse embryo dissection, genotyping and phenotyping. They will have excellent organisational skills and a demonstrable aptitude for research. Experience in conducting zygote microinjections, embryo transfer, MeDIP-seq or RNA-seq (and/or other high-throughput technologies), and/or basic bioinformatic analysis is desirable but not essential. Animal husbandry experience and Home Office Training would be an advantage.

Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will be appointed at Research Assistant level, which will be amended to Research Associate once the PhD has been awarded.

Salary Ranges: Research Assistant: £32,296-£34,866, Research Associate: £36,924- £45,163

Fixed term: The funds for this post are available for 30 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a security check.

Apply

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

To apply for this post, please upload your CV and a letter detailing why you want to be a part of this project and how this post will be a good stepping-stone for your career. We also need the names and contact details for two people, who can provide a professional reference.

The deadline for applications is 31 March 2025 and we aim to hold in-person or Zoom interviews for the shortlisted candidates shortly after the closing date.

Informal enquiries can be made to Prof William Colledge, whc23@cam.ac.uk.

Please quote reference PM45144 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The Department of Physiology, Development and Neuroscience particularly encourages candidates from a BME background to apply for this vacancy.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

SCHOLARSHIP AWARD: £28,738.00 (Subject to change)

A three-year Senior Clinical Training Scholarship in Small Animal Medicine (Residency) is available, to start on 11 August 2025. The training programme covers all aspects of small animal medicine, including cardiology, oncology, medical neurology, diagnostic imaging and clinical pathology, and is approved by the European College of Veterinary Internal Medicine.

The Scholar will register for the Diploma of the European College of Veterinary Internal Medicine. The training programme requires participation in the Department's clinical service, including the out-of-hours rota, in addition to small-group teaching of veterinary students.

An applicant must be a Member of the Royal College of Veterinary Surgeons, or hold a veterinary degree that qualifies them for membership. Completion of an appropriate internship or a minimum of two years' experience in small animal practice, during which you have gained knowledge of UK veterinary regulations and practices, is essential.

Closing date for applications: Midnight on Monday, 10 February 2025.

Interviews will be held early April 2025.

Informal enquiries should be directed to Nick Bexfield, Clinical Director of Small Animal Services, by email: nb289@cam.ac.uk

A SCTS application form (SCTS1) and information pack can be downloaded from the following website: https://www.vet.cam.ac.uk/job

Applicants should supply a completed SCTS Application Form (SCTS1), Curriculum Vitae and Covering Letter giving reasons for wishing to undertake this SCTS in the Department of Veterinary Medicine, University of Cambridge.

Applications should be submitted via e-mail to vetmed@vet.cam.ac.uk with the above documents as one attachment no later than the closing date stated.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Please note: The ability to take up this Scholarship is contingent upon you being able to evidence your right to work in the UK, or through gaining the right to work via the UK immigration system. Evidence will need to be provided before an offer can be made. Regrettably, this Scholarship is not suitable for sponsorship via the Skilled Worker or Temporary Worker visa routes as the minimum requirements cannot be met.

As part of a collaboration with the University of Oxford, the University of Cambridge is seeking a highly motivated Postdoctoral Research Associate or Research Assistant (with an Undergraduate level degree as a minimum) to join the laboratory of Professor Elizabeth Soilleux on a newly funded, exciting CRUK-funded project, developing and validating a new diagnostic test for T-cell lymphoma. The test is likely to be adopted into clinical practice during the later stages of the 3-year project.

This 3-year role focuses on careful validation of tissue-based staining and provides an opportunity to interface with and understand clinical services and healthcare challenges. It provides opportunities to learn about tissue morphology, as well as gaining experience in automated and manual tissue handling and staining processes, primarily using immunohistochemistry, immunofluorescence and high sensitivity in situ hybridisation. Corroborative approaches using cell culture and molecular techniques will also be important.

There will be opportunities to present data at conferences and to write both primary research and review papers. The successful applicant will be expected to provide singlehanded or collaborative supervision to undergraduate students and Masters students, within a supportive and collegial laboratory environment.

Key Responsibilities:

• Cell culture
• Molecular biology (nucleic acid extraction, PCR, RT-PCR, Q-PCR).
• Collating and clinicopathologically annotating cohorts of patient biopsy samples, in collaboration with clinical colleagues, as needed.
• Automated (and occasionally) manual staining by immunohistochemistry, in situ hybridisation and immunofluorescence.
• Ensuring compliance of the laboratory with Human Tissue Act (England and Wales, 2004).
• Providing Human Tissue Act training and mentorship to other laboratory members, principally students.
• Liaising with industrial and academic collaborators, both nationally and internationally.
• Supervising or co-supervising student projects, as appropriate.

Essential Requirements:

• A Relevant Undergraduate Degree (Appointment at Research Assistant Level).
• Strong molecular biology skills, including nucleic acid extraction and PCR.
• A willingness to work with a broad range of academic, clinical and industrial collaborators.
• Excellent organisational and communication skills, with the ability to work effectively in multidisciplinary teams.

Desirable:

• Experience in training or mentoring students or other laboratory members.
• A strong track record in writing manuscripts for publication.
• PhD (or equivalent experience) in spatial imaging, tissue-based research approaches (including immunohistochemistry/ in situ hybridisation) or molecular biology (Essential for appointment at Research Associate Level).
• A Masters Degree

Please read attached further particulars document for more information.

Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will be appointed at Research Assistant level, which will be amended to Research Associate once the PhD has been awarded. Those with equivalent experience to a PhD, but who have not undertaken or not yet completed a doctoral qualification will be eligible to be appointed at Research Assistant level.

Click the 'Apply' button below to register for an account with our recruitment system and apply online.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Applications are welcome from internal candidates who would like to apply for the role on the basis of a secondment from their current role in the University.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Any informal queries regarding this position should be directed to Professor Elizabeth Soilleux : ejs17@cam.ac.uk

Queries regarding the application process should be directed to Miss Ellie Watson (HR Administrator): ew649@cam.ac.uk

Please quote reference PK45055 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Applications are invited for a Postdoctoral Research Associate position in the group of Dr Erik Clark at the Department of Genetics in central Cambridge. We are looking for a talented and enthusiastic individual to join a small interdisciplinary team investigating the robust patterning of the early Drosophila embryo. The role will involve developing and applying cutting-edge imaging approaches in Drosophila and Tribolium embryos, plus computational analysis of the resulting data.

Your primary responsibility will be to establish and optimise new techniques in the lab, including live imaging of gene expression in Drosophila embryos and multiplexed fixed imaging of gene expression in Tribolium embryos. Significant previous experience with Drosophila and Tribolium husbandry, advanced imaging, and image analysis is essential for the role. Experience with CRISPR/Cas9 would also be helpful.

The context of the project is the evolution of anteroposterior patterning networks across insects. A background in and enthusiasm for insect evolutionary developmental biology is highly desirable for the role.

The role will involve independently leading your own project while teaching and learning from other lab members and external collaborators. A friendly, collaborative attitude and good organisational and communication skills are essential.

Suitable applicants should hold a PhD in a relevant scientific discipline. They should be able to demonstrate a thorough working knowledge of relevant wet-lab, imaging, and computational techniques, and be confident in delivering training in these techniques to other lab members. They should also have experience in presenting research to different audiences, contributing to publications, and helping to lead group discussions.

The position is fixed term for a period of 18 months in the first instance and is available from 1st April 2025.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries about the role are welcome and should be directed to Dr Erik Clark ec491@cam.ac.uk

Please quote reference PC45080 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

A research assistant position is available in the Luginbuehl group funded by the ERC Starting Grant "Harnessing mechanisms for plant carbon delivery to symbiotic soil fungi for sustainable food production". This project explores carbon transfer in the arbuscular mycorrhizal symbiosis with the aim to optimize symbiotic nutrient exchange in the model crop rice. The post is available at 50% for two years in the first instance, with the possibility of further extension.

The successful candidate will work closely with other members of the team. The candidate will generate stable transformants of rice and other plant species and will be involved in plant management and maintenance as well as molecular biology experiments.

Preferred start date: 1st April 2025.

Fixed-term: The funds for this post are available for 2 years in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please notice that if you have not received any news from us 1 month after the closing date you should consider that on this occasion your application has not been successful.

Please quote reference PD45058 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

The Department of Genetics is one of 13 departments within the School of Biological Sciences. The main building of the Genetics Department is home to 22 research groups, 117 staff and 30-40 undergraduate students, and comprises laboratories, teaching classrooms, offices and support facilities on 4 floors. The Genetics Department teaches at all levels of undergraduate education and provides input to many undergraduate courses. The successful applicant will be part of the professional support staff team and be responsible for providing technical support for teaching activities across the Department.

We are looking for a proactive and responsible Technician who is confident working with different research groups and leading the organisation and provision of resources for laboratory based practical teaching classes. The ideal applicant will have practical experience of supporting biological research with a high degree of accuracy and be able to demonstrate knowledge of the principles, processes and general concepts related to Laboratory Technician work.

A key element of the role supports staff across the Department by monitoring the stock of consumables, ordering replacements and assisting with the maintenance of laboratory equipment. The role holder will be responsible for purchasing laboratory consumables and minor equipment to an agreed budget by placing orders through the University's financial system (CUFS), checking supplies and specifications with end users, resolving issues with suppliers and requesting quotes.

As this role interacts with academics, research staff and students, strong communication skills are essential with an aptitude for identifying technical support needs and resolving problems quickly. The role holder will also support our Department Safety Officer to ensure that health and safety procedures are observed at all times.

The role is based in the Department of Genetics but requires some movement between other local Departments when setting up practical classes in shared teaching facilities. Therefore, short periods of physically strenuous activity will also be required.

The position is offered on a permanent basis, subject to satisfactory completion of a 6 month probation period. This is a part-time role working 22 hours per week, Monday to Friday.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

For informal enquiries about the role please contact Amie Baker, aew47@cam.ac.uk

Please quote reference PC45063 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Supervisors: Anne E. Willis and Ritwick Sawarkar (MRC Toxicology Unit), Giandomenico Turchiano and Roberto Nitsch (AstraZeneca)

PhD Studentship: Enhancing Genome Editing Efficiency and Stability through Analysis of DNA Mobility Post-Double Strand Breaks

Applications are invited for a 3.5 year PhD studentship based within the MRC Toxicology Unit, University of Cambridge, with extended industry experience at AstraZeneca (Cambridge, UK). The student will be working on a collaborative project jointly supervised by Anne E. Willis and Ritwick Sawarkar (MRC Toxicology Unit), Giandomenico Turchiano and Roberto Nitsch (AstraZeneca).

We are seeking a highly motivated individual to undertake a combined experimental/computational project on CRISPR/ Cas9-related therapeutics using human models. This is a mixed wet/dry lab project combining human cell genomics, microscopy and sequencing-based approaches. The purpose of the studentship is to apply molecular cell biology approaches to (i) understand mechanisms of CRISPR off-targets and (ii) advance the scientific understanding of DNA mobility post-double strand breaks.

This studentship offers a unique training opportunity for engagement with leading academic and industry partners to understand the mechanism by which CRISPR therapeutics may cause genomics off-targeting. Rotating between laboratories at the University of Cambridge and AstraZeneca the student will gain experience in a breadth of experimental and analytical techniques, including: molecular biology, cell culture, microscopic assays, DNA sequencing, and statistical data analyses.

Applicants should have or shortly expect to obtain a first or good upper second-class degree from a UK university, or an equivalent standard from an overseas university, in a relevant subject such as Biomedical Science. Strong analytical skills, in addition to creativity, curiosity, enthusiasm, and the ability to work in a team are essential.

This studentship is open to UK citizens or overseas students who meet the UK residency requirements (home fees) or are able to augment the funds to cover the extra costs associated with international student fees. Full details of the University's entrance requirements are specified here: http://www.graduate.study.cam.ac.uk/application-process/entry-requirements.

REFERENCES: 1) 1. Turchiano et al. Quantitative evaluation of chromosomal rearrangements in gene-edited human stem cells by CAST-Seq. Cell Stem Cell 2021 2) Selvaraj et al. High-efficiency transgene integration by homology-directed repair in human primary cells using DNA-PKcs inhibition. Nat. Biotech. 2024

All formal applications will need to be made through the University Application Portal: https://www.postgraduate.study.cam.ac.uk/courses/directory/bltopdtox

Your online application must include a CV (including full details of all University course grades to date), contact details for two academic or professional referees and a personal statement of interest.

Full funding covering Maintenance and the University Composition Fee (Home Fee rate) is provided for the studentship, with effect from 1 October 2025.

If you have any queries regarding the application process, please contact hradmin@mrc-tox.cam.ac.uk

Further information can be found on our website: https://www.mrc-tox.cam.ac.uk

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

The Microscopy Bioscience Platform in the School of Biological Sciences is recruiting for an enthusiastic microscopy technician to join the Electron Microscopy team. The facility provides advanced imaging services, currently serving over 100 research groups in the University as well as external, commercial users. At present the centre has an FEI Verios 460 SEM and Tecnai G2 TEM with associated sample preparation equipment. This role will provide essential support to improve research throughput of our state-of the-art EM facility. The role holder will be responsible for assisting the Electron Microscopy Specialist and Lead Electron Microscopist in the delivery of a professional and comprehensive EM service. This will include all aspects of project design, from initial discussion of methodology, to sample preparation, imaging and data interpretation.

The role holder will work closely with the senior members of the team in order to achieve the platform's aims of providing access to advanced imaging capabilities in a sustainable environment through efficient cost recovery. This role requires a real enthusiasm for electron microscopy and would be ideal for someone who wishes to develop their microscopy skills with the guidance of our expert EM staff.

You should have practical experience of biological scientific research work, a high degree of precision in following protocols and excellent communication skills. Please refer to the further particulars document for a full list of the essential knowledge, skills and experience required for the role.

Informal enquiries are welcomed and should be addressed to Filomena Gallo, fg337@cam.ac.uk.

Limited funding: The funds for this post are available for 4 years in the first instance.

Apply

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

On the online form, in the suitability for the role section, you should explain the reasons for your application and how your knowledge, skills and experience match the requirements of the role. The full contact details for two professional referees should be provided, one of whom should be your current line manager. Please note that we will assume that you are happy for us to approach your referees at any stage, unless you indicate otherwise in the space provided on the form.

The closing date for applications is midnight on 14 March 2025. Interviews will take place w/c 6th April 2025.

Please quote reference PM45033 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Remote sensing of fire effects on soil organic carbon

Wildfire occurrence and severity are known to be influenced by ecosystem hydrology, with peatland fires depending on soil moisture. Recent work has demonstrated the large impact of wildfires on soil drying, which can have implications for further wildfires and long-term carbon fluxes from peatlands.

This postdoctoral research associate post will use remote sensing data to assess wildfire occurrence, severity and ecosystem recovery, combined with remote sensing of soil moisture and plant water content.

The post will initially be for 9 months with the possibility of a 15-month extension. It will be based in Cambridge but allow for travel to Stanford University in California to collaborate with other researchers, Prof. Alexandra Konings, and spend time with Adam Pellegrini's Stanford-based lab. Collaborations at Cambridge will include Prof. David Edwards.

Skills required: extensive Python/R experience evaluating remote sensing datasets at the global scale. Familiarity with MODIS, SMAP, VOD and other products evaluating ecosystem water content and wildfires. Familiarity with peatland distribution maps and carbon fluxes.

Fixed-term: The funds for this post are available for 9 months in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please notice that if you have not received any news from us 1 month after the closing date you should consider that on this occasion your application has not been successful.

Please quote reference PD45057 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

People are at the heart of everything we do at Pathology, so why not join our Central Services Domestic team as a Domestic Assistant (Part-Time). We can offer a welcoming work environment where you can feel valued, encouraged to develop, and supported to achieve your full potential.

You will support the Domestic Team in undertaking cleaning and portering services at the Downing Site of the Department of Pathology which will include cleaning laboratories, the library, toilets, the canteen and common room/areas to maintain the appearance of the Department to a high standard.

Ideally you will have some relevant experience of laboratory or office cleaning, although an aptitude for this type of work is more important as full training will be provided. Good communication skills with the ability to follow written and verbal instructions, particularly regarding the safe use of chemicals, the ability to prioritise your workload with the minimum of supervision and to work both independently and as part of a team are essential. Please see attached Further Particulars document.

What we Offer

*Our Professional Services staff play a fundamental role in the School's academic vision of the pursuit of education and research at the highest levels of excellence. The University of Cambridge offers excellent benefits, extensive opportunities in a stimulating environment.

*The University salary structure includes automatic service-related pay progression in many of its grades and an annual cost of living increase. In addition to this, employees are rewarded for outstanding contribution through a number of regular pay progression schemes. Staff also benefit from a generous annual leave entitlement.

*The University offers employees a wide range of competitive benefits, from health care cash plans to childcare, a cycle to work scheme, to shopping and insurance discounts.

*University-led initiatives in the areas of equality, diversity and wellbeing include staff and students networks. These include the Women's Staff Network, the Disabled Staff Network, the Black, Asian and Minority Ethnic Staff Network, Parents and Carers and the LGBT+ Network. We also hold a wide range of Equality and Diversity events on a regular basis.

*Wellbeing at Cambridge is a University-wide initiative aiming at supporting and maximising the health and wellbeing of staff. It encompasses a network of Wellbeing Advocates, who provide guidance and general signposting about wellbeing issues, including mental or physical health and Dignity @ Work concerns.

*The University offer a range of family-friendly policies, including maternity, adoption and shared parental leave. In addition, workplace nurseries, childcare vouchers, a childcare salary sacrifice scheme and a high-quality holiday play scheme are available to help support University employees with caring responsibilities.

Contact Caius Liu for an informal chat on cl870@cam.ac.uk and check out our website: https://www.path.cam.ac.uk/

Temporary cover: This post is fixed-term to cover Maternity Leave for 12 months or until the return of the post holder, whichever is the earlier.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

We welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Any informal queries regarding this position should be directed to Mr Caius Liu (Facilities Manager) : cl870@cam.ac.uk

Queries regarding the application process should be directed to Miss Ellie Watson (HR Administrator): ew649@cam.ac.uk

Please quote reference PK45031 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

An exciting opportunity for a Postdoctoral Research Associate has emerged within the Department of Pathology's Ferguson Laboratory. The successful applicant will join a three-year research project, defining cellular and molecular details of how viruses are detected by the human innate immune system. You will be primarily working in the lab of Dr Brian Ferguson whilst also working in collaboration with structural biologists in the Chaplin Lab (University of Leicester) and clinical researchers in the Thomas Lab (CIITID, Cambridge). We provide a supportive research environment that focuses on research excellence, integrity, and respect.

Further information about the Ferguson Lab is available here: www.fergusonlab.path.cam.ac.uk

Role Overview

The successful applicant will use cellular, molecular and biochemical tools to understand how DNA viruses are sensed by the innate immune system. We are particularly interested in defining how the DNA repair machinery interfaces with viral nucleic acid sensing and how DNA viruses combat these processes using immunomodulatory proteins.

Key focuses of the project will be in determining the molecular complexes that are formed during infection and DNA damage, which are responsible for initiating an antiviral response. This project also aims as to understand how different DNA virus families counter these host innate immune sensing mechanisms. Approaches taken to answer these questions will include CRISPR engineering of mammalian cells, proteomics, transcriptomics, virus engineering and defining intracellular signalling mechanisms following receptor stimulation and/or infection.

Key Responsibilities

*Production and analysis of recombinant DNA viruses

*Development of engineered cell lines for signalling complex analysis

*Investigation of cell signalling processes

*Analysis of proteomic and transcriptomic datasets

*Driving collaborations with collaborative (structural and clinical) labs

*High quality record keeping

*Presentation of data at local and international meetings

The successful candidate must have (or be close to submitting) a PhD in Virology, Immunology or Cell Signalling. Those who have not yet submitted would be appointed at Research Assistant level, which would be amended to Research Associate upon submission. The successful applicant will also be proficient in cell biology or molecular virology (please check Further particulars document attached).

Ideally, successful applicant will have an interest in innate immunity, experience in proteomics, have experience with CRISPR engineering of mammalian cells and/or have specific experience with poxviruses or adenoviruses.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Applications are welcome from internal candidates who would like to apply for the role on the basis of a secondment from their current role in the University.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Any informal queries regarding this position should be directed to Dr Brian Ferguson : bf234@cam.ac.uk

Queries regarding the application process should be directed to Miss Ellie Watson: ew649@cam.ac.uk

Please quote reference PK45022 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

We are seeking a creative and motivated postdoctoral researcher to work on an ESRC-funded project at Dr Deborah Talmi's Emotional Cognition Lab at the Department of Psychology, University of Cambridge (https://dtalmi.wixsite.com/emotional-cognition), working collaboratively with Prof Rik Henson at the MRC Cognition and Brain Sciences Unit (https://www.mrc-cbu.cam.ac.uk/people/rik.henson) and Prof Emily Holmes (Uppsala, Sweden).

This post will involve conducting innovative computational research on human memory, contrasting two theories on how memory changes when experiences are traumatic. The primary objective of this position is to develop temporal context models which can integrate new empirical evidence collected at the lab as part of this ongoing project.

Please note there is a requirement for this position to work from the office in central Cambridge

The successful candidate(s) will have

_ a strong quantitative background

_ demonstrable interest in computational neuroscience and/or mathematical psychology

_ obtained (or be close to the completion of) a PhD or equivalent in computational neuroscience, computational cognitive science, physics, mathematics, computer science, machine learning, statistics, engineering or a related field.

Ideally candidates will have:

_ previous experience in computational neuroscience of memory, especially with model-based analyses of behavioural data

_ hands-on experience with how experimental data is collected in humans

_ sufficient programming skills to run numerical simulations and use large-scale optimization packages

Fixed-term: The funds for this post are available until 1 October 2026 in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

For informal inquiries, please contact Deborah Talmi: dt492@cam.ac.uk

Closing Date: Wednesday 26th February 2025 at 12 Midnight

Planned interview date: 7 March 2025

Please quote reference PJ45024 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

This role is an excellent opportunity for a driven ambitious individual to develop their skills and experience as the Innovation Pathway Manager (Ideation) at the Milner Therapeutics Institute (MTI). The role holder will become a key connector for research-based innovation, working closely with other stakeholders in the Cambridge NeuroWorks ARIA Activation Partnership.

The partnership comprises a consortium of organisations (Cambridge University Health Partners, several departments of the University of Cambridge, Babraham Research Campus, Cambridge & Peterborough NHS Foundation Trust, Cambridge Network, and Vellos). The partners will provide creative talent with access to the expertise and resources needed to progress a new generation of neuro-technologies designed to treat conditions such as depression, dementia, chronic pain, epilepsy and injuries to the nervous system.

The Innovation Pathway Manager (Ideation) will implement, nurture and develop an inclusive neurotechnology community and ensure compliance and smooth operation throughout each phase of the programme. This role directly impacts the development and validation of novel neurotechnology concepts through structured support and access to curated expertise.

The Innovation Pathway Manager will work closely with the "What If" Leads (Milner Institute Directors; Head of Entrepreneurship; COO of Vellos), the Innovation Pathway Manager (Proof of Concept) counterpart role at the Maxwell Centre, and Cambridge NeuroWorks team members. They will plan and support the development of the "What If" ideation and experimental pathway programme, building upon trend scanning, ideation, venture feasibility assessments, planning experimental setups, managing resource allocation, and fosters community engagement with both internal and external stakeholders.

The Milner Therapeutics Institute (MTI) is a purpose-built research institute at the University of Cambridge, with an overarching vision to convert pioneering science into therapies by driving academic-industry partnerships. The MTI is breaking new ground in academic/industry interactions and demonstrates a world-leading model of start-up companies, academics and pharma working side by side at the bench. The MTI environment offers a unique opportunity to work at the interface of academia and industry, applying ground-breaking technologies to drug discovery and patient treatment.

The ideal candidate is educated to Masters/PhD level or demonstrate equivalent senior practical experience, relevant to neurosciences / medical sciences / health tech, and has worked in research / entrepreneurial environments. They will possess highly developed organisational and project management skills, with the ability to communicate effectively with stakeholders at all levels.

If you are looking for a challenge and opportunity to develop yourself, your network, the programme and the impact it unlocks, then you will find this role very rewarding.

Fixed term (subject to funding, current end date 30 September 2027)

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries can be directed to Alexandra Huener, Head of Entrepreneurship ah930@cam.ac.uk.

Please quote reference PR44929 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

The University of Cambridge is seeking a highly motivated Research Assistant or Postdoctoral Research Associate to join the laboratories of Professor Ian Goodfellow and Dr Jenny Molloy on an exciting Wellcome Trust funded project focused on putting genomic surveillance at the heart of outbreak response. The ARTIC Network is a global initiative aimed at enhancing pathogen detection and outbreak response through real-time genome sequencing. This role focuses on developing and validating sequencing protocols for infectious disease surveillance, particularly in resource-limited environments.

Key Responsibilities:

• Design, optimize, and implement sequencing protocols suitable for outbreak investigations and pathogen surveillance.

• Develop and produce training materials to support the deployment of sequencing methodologies.

• Conduct field testing of sequencing workflows in collaboration with international partners.

• Organize and deliver hands-on training workshops to support capacity building in genomic surveillance.

• Contribute to open-access dissemination of methodologies, including protocol development and bioinformatics workflows.

• Work collaboratively within the ARTIC Network, engaging with global public health and research organizations.

Essential Requirements:

• A PhD (or equivalent experience) in molecular biology, virology, genomics, bioinformatics, or a related field.

• Experience in next-generation sequencing (NGS), particularly amplicon-based or metagenomic approaches.

• Strong molecular biology skills, including PCR, library preparation, and nucleic acid extraction.

• Experience in training or capacity-building initiatives, preferably in low-resource settings.

• Excellent organizational and communication skills, with the ability to work effectively in international, multidisciplinary teams.

Desirable Skills:

• Experience in developing field-adapted sequencing protocols.

• Familiarity with bioinformatics tools and pipelines for pathogen genomics.

• Previous involvement in outbreak response or infectious disease surveillance projects.

• Willingness to travel for collaborative visits and training workshops.

This is an exciting opportunity to contribute to real-world infectious disease outbreak response and genomic surveillance efforts, ensuring equitable access to cutting-edge sequencing technologies.

Applications are welcome from internal candidates who would like to apply for the role on the basis of a secondment from their current role in the University.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will be appointed at Research Assistant level, which will be amended to Research Associate once the PhD has been awarded.

Fixed-term: The funds for this post are available for 18 months in the first instance (with an opportunity to extend up to 48 months).

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Please quote reference PK44942 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Applications are invited for a fully-funded 4-year PhD studentship based in the Department of Pathology at the University of Cambridge under the supervision of Dr Arwen Altenburg starting October 2025.

Major histocompatibility complex (MHC) class I molecules play an essential role in alerting immune cells to cellular changes in infected and cancer cells. They do this by presenting peptides derived from pathogen and tumour proteins to immune cells. To evade immune detection, viruses have evolved strategies to manipulate MHC class I or other proteins in the antigen processing and pathway. Our research explores the MHC class I pathway in virus infections to enhance our understanding of MHC class I biology and virus-host interactions. Through the characterisation of these dynamics, we aim to enable future innovation of vaccines and therapeutics.

For more information please see here: https://www.path.cam.ac.uk/graduate/fully-funded-studentships

Funding* will cover the student's stipend at the current Research Council rate and University Fees. The studentship will be funded for four years from October 2025.

The studentships are available to students who qualify for UK Home fees. Please check for eligibility details; https://www.postgraduate.study.cam.ac.uk/finance/fees/what-my-fee-status.

Applicants should hold (or expect to obtain) the equivalent of a UK 2.1 or higher in an undergraduate honours or Masters degree in a relevant subject. The studentship is open to those eligible for the Home rate of University fees.

All applications should be made online via the University's Applicant Portal; https://apply.postgraduate.study.cam.ac.uk/applicant/login?dswid=6631 for a PhD in Pathology (BLPA22). Applications should include academic transcripts, CV, statement of purpose and 2 references. An application is only complete when all supporting documents, including the 2 academic references, are submitted. It is the applicant's responsibility to ensure their referees submit their references before the closing date (2nd March 2025). Please also explain your motivation why you wish to pursue a PhD in this area, outline your research interests and background, and describe the qualities and experience you will bring to the role.

Please quote reference PK44971 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Somatic evolution of the immune response to chronic inflammation and liver cancer progression through single-cell multiomics

Applications are invited for a fully-funded 4-year PhD studentship based in the Department of Pathology at the University of Cambridge under the supervision of Dr Heather Machado starting October 2025.

Our body's immune system is one of the most powerful tools in the fight against cancer. An improved understanding of how the adaptive immune system evolves in the context of cancer, including the effects of chronic inflammation and the phenotypic changes from premalignancy to cancer progression, could lead to improved cancer outcomes. However, these immune dynamics are difficult to study directly in humans due to longitudinal sampling constraints. To overcome these obstacles, this project will apply state-of-the-art lineage tracing techniques and single-cell multiomics to track CD8+ T cell dynamics in an inflammatory premalignancy and the resulting liver cancer.

For more information please see here: https://www.path.cam.ac.uk/graduate/fully-funded-studentships

Funding* will cover the student's stipend at the current Research Council rate and University Fees. The studentship will be funded for four years from October 2025.

The studentships are available to students who qualify for UK Home fees.

Please check for eligibility details; https://www.postgraduate.study.cam.ac.uk/finance/fees/what-my-fee-status.

Applicants should hold (or expect to obtain) the equivalent of a UK 2.1 or higher in an undergraduate honours or Masters degree in a relevant subject. The studentship is open to those eligible for the Home rate of University fees.

All applications should be made online via the University's Applicant Portal for a PhD in Pathology (BLPA22). Applications should include academic transcripts, CV, statement of purpose and 2 references. An application is only complete when all supporting documents, including the 2 academic references, are submitted. It is the applicant's responsibility to ensure their referees submit their references before the closing date. Please also explain your motivation why you wish to pursue a PhD in this area, outline your research interests and background, and describe the qualities and experience you will bring to the role.

Please quote reference PK44919 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.