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School of the Biological Sciences

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DNA Sequencing is an essential tool in all areas of the Biological Sciences, supporting translational research, advances in disease diagnostics and treatment. Researchers use DNA sequencing to understand genetics variations and mutations that may play a role in development and disease.

Genomics Facilities across the School of Biological Sciences provide high quality DNA sequencing services using a variety of equipment and techniques. Our staff also offer support throughout experiments, from project design to library preparation, sequencing and analysis.

School-based Facilities open to all include:

 

Genomics Facility at the Department of Biochemistry


Equipment available in the facility:

  • Applied Biosystems 3730XL
  • Applied Biosystems 3130XL
  • Agilent Bioanalyzer
  • Covaris S220
  • Illumina MiSeq
  • Illumina NextSeq
  • Oxford Nanopore Mk1C
  • Sage Science Blue Pippin

Location

The facility is based in the Department of Biochemistry (see map)


Contact

Facility Manager: Shilo Titus

Email: Sequencing Team


Access

The DNA Sequencing facility is open to all members of the University.


More information and bookings

 

Genomics Facility at the Wellcome/Cancer Research UK Gurdon Institute


Sequencing equipment and techniques available in the facility:

  • Illumina NovaSeq 6000

Location

The facility is based in the Gurdon Institute (see map)


Contact

Academic Lead: Charles Bradshaw

Facility Technician Kay Harnish

Email: sequencing@gurdon.cam.ac.uk


Access

The facility is open to all members of the University and external members.


More information and bookings

 

Cambridge Genomic Services at the Department of Pathology


Sequencing equipment and techniques available in the facility:

  • Illumina NextSeq 500
  • Illumina Miseq
  • Access to NextSeq 2000
  • Chromium Controller (10X single-cell sequencing)
  • Oxford Nanopore
  • Agilent Tapestation and Agilent Bioanalyser
  • Covaris
  • Affymetrix Microarray platform
  • Illumina Microarray platform
  • Bioinformatic analysis

Location

The facility is based in the Department of Pathology (see map)


Contact

Academic Lead: Anton Enright

Facility Managers: Alexandra Karcanias and Julien Bauer

Email: cgs@path.cam.ac.uk


Access

The is open to all members of the University and external users.


More information and bookings

 

Genomics Facility at the Wellcome - MRC Cambridge Stem Cell Institute


Services available in the facility:

  • Project planning and advice about your NGS project
  • Covaris E220 shearing of DNA/RNA samples; chromatin samples
  • Sample QC
  • Library preparation and QC
  • Bespoke projects will be considered
  • Advice on choice of sequencing platform
  • Close interaction with Bioinformatics support facility

​The sequencing itself is not done in-house, but at CIGC in Cambridge which allows access to the latest Illumina sequencing technology.


Location

The facility is based in the Cambridge Stem Cell Institute (see map)


Contact

Genomics Facility Manager: Maike Paramor

Email: ngs-core@jcbc.cam.ac.uk


Access

The facility is open to all members of the University and external users from the academic and private sectors.


More information and booking