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All living organisms regenerate as part of everyday life to maintain tissue and organs, however more complex animals such as mammals and humans have limited capabilities. Researchers in Cambridge are working together to learn lessons across tissues, systems and scales to make human limb and organ regeneration possible.

 

 

 

Collaboration and Engagement

With the view to develop cross-disciplinary concepts focussed on fundamental questions in regenerative bioscience, the Reproduction, Development and Lifelong Health Research Theme organised a workshop bringing together scientists who work on tissue growth and regeneration from diverse perspectives to learn from each other and better understand how we can unlock regenerative potential across different tissues, scales and organisms. 

Speakers spanned 7 Departments: Cambridge Stem Cell Institute, Genetics, Gurdon Institute, Pharmacology, Plant Sciences, Sainsbury Laboratory and Zoology. The meeting comprised a series of short talks and included areas such as plant growth, human development, animal tissue regeneration and evolutionary perspectives. Members of the University can find out more on the School Information Hub.

 

people in a room with screen at the back      people sitting at tables in a room

Complex tissue regeneration across scales and systems workshop, Pitt Building, May 2022

Key Collaborators

Maria Alcolea, Cambridge Stem Cell Institute

Can Aztekin, EPFL

Sumru Bayin, Gurdon Institute

Elia Benito Gutierrez, Zoology

David Fernandez-Antoran, Gurdon Institute

Andrew Gillis, Zoology

Dino Giussani, Physiology, Development and Neuroscience

Jim Haseloff, Plant Sciences

Henrik Jonsson, Sainsbury Laboratory

Walid Khaled, Cambridge Stem Cell Institute

Golnar Kolahgar, Physiology, Development and Neuroscience

Emma Rawlins, Gurdon Institute

Andrew Sharkey, Pathology

Sanjay Sinha, Cambridge Stem Cell Institute

Ben Steventon, Genetics

Mekayla Storer, Cambridge Stem Cell Institute

Catherine Wilson, Pharmacology

Work with us

We welcome opportunities to collaborate with industry partners, policy makers and academics. If you are interested in working with us, please contact Dr Abi Herrmann, Research Strategy Facilitator.

Key Publications

To regenerate or not to regenerate: Vertebrate model organisms of regeneration-competency and -incompetency

Aztekin, CStorer, MAWound Rep Reg2022113. doi:10.1111/wrr.13000


Single-cell morphometrics reveals ancestral principles of notochord development

Andrews TGR, Pönisch W, Paluch EK, Steventon BJ, Benito-Gutierrez E.  Development 15 August 2021; 148 (16): dev199430. doi: https://doi.org/10.1242/dev.199430


High-Throughput 3D Phenotyping of Plant Shoot Apical Meristems From Tissue-Resolution Data

Åhl H, Zhang Y, Jönsson H. Frontiers in Plant Science 2022 Apr 18; 13:827147.

doi: 10.3389/fpls.2022.827147