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Current jobs in the MRC Toxicology Unit at the University of Cambridge.
Updated: 17 min 11 sec ago

Proteomics Technical Lead (Fixed Term)

Mon, 15/01/2024 - 00:00

We are looking to appoint a Proteomics Technical Lead to join the Proteomics Facility at the MRC Toxicology Unit, University of Cambridge. The facility performs a fundamental role in tackling proteomic-based problems for the Unit's scientific programmes.

As the Proteomics Technical Lead you will work on several projects in response to the needs of our researchers and actively participate in mass spectrometry/proteomics method development. You will be responsible for sample preparation, reporting results to scientists, operating and maintaining specialist equipment and general laboratory management.

You will ideally be skilled in a broad range of methods in proteomics and biological mass spectrometry and chromatography and have excellent communication skills to enable to you work on projects which are often transient and time critical. You will need to have a degree in a scientific discipline, preferably with a PhD. You will also be an excellent communicator and team player, with the ability to manage a laboratory including health and safety, purchasing and equipment maintenance.

The Medical Research Council Toxicology Unit is an internationally renowned institution focussed on the delivery of field-changing mechanistic insights into toxicology and disease and is based in the newly refurbished Gleeson building, central Cambridge.

Fixed-term: The funds for this post are available until 31 March 2027 in the first instance. Funded by the MRC.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

If you have any queries regarding the application process, please contact hradmin@mrc-tox.cam.ac.uk

Further information can be found on our website: https://www.mrc-tox.cam.ac.uk

Please quote reference PU40131 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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Executive Assistant (Fixed Term)

Tue, 19/12/2023 - 00:00

An opportunity has arisen for an experienced Executive Assistant to join the MRC Toxicology Unit at the University of Cambridge.

The successful candidate will play a vital role providing full administrative support to the Unit Director and ensuring the smooth running of the Director's Office. Main duties will involve optimising the Director's time by expert management of the diary and travel arrangements, dealing with correspondence, arranging meetings, servicing committees including the taking of minutes and working with people at all levels to build effective working relationships. Other duties will include financial administration, providing support for HR and facilities management and arranging general events. The post holder will also have line management responsibility for administrative staff.

You will have significant experience of working as a PA/Executive Assistant at a senior level, be able to demonstrate excellent communication skills - particularly written, have a keen eye for detail, the ability to apply sound judgement and to work in a discreet and confidential manner. It is expected that you will be educated to the level of HND/HNC/Level 4/5 vocational qualification or have equivalent level of practical experience. Line management experience is essential. Experience of working in a research environment would be beneficial.

Fixed-term: The funds for this post are available for 12 months in the first instance, funded by the MRC

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

If you have any queries regarding the application process, please contact hradmin@mrc-tox.cam.ac.uk

Further information can be found on our website: https://www.mrc-tox.cam.ac.uk

Please quote reference PU39871 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs

Research Associate (Fixed Term)

Mon, 18/12/2023 - 00:00

The Mennella research group at the University of Cambridge is focussed on investigating pathways that are regulated during airway cell differentiation and mucociliary clearance. These are key processes protecting the lung epithelial surface, when it is exposed to particulate matter, aerosols and infectious agents. We are a strong and diverse team of researchers spanning multiple scientific disciplines, including imaging, omics and AI based data analysis.

We are looking for a highly independent research associate with significant experience in airway or stem cell biology and primary cellular models to join our group for a collaborative project with Elizabeth McInnes, a toxicological pathologist at the agrochemical company Syngenta. The project will evaluate the potential mechanisms of cellular and molecular toxicity of plant protection products in the airway. The project will focus on developing New Alternative Methodologies (NAMs) to replace laboratory animal studies, to predict toxicity in plant protection products, using advanced imaging technologies (super-resolution microscopy and Volume EM) and omics tools (transcriptomics and proteomics).

The project offers an exciting opportunity to integrate airway molecular and cell biology methods with high-throughput imaging, sequencing and protein-protein interactions methods, to enable characterisation/obtain novel insights into multiprotein signalling complexes that regulate airway defence. We are particularly interested in candidates who are enthusiastic about combining screening with mechanistic followups. The ideal candidate will have track record of timely project delivery, strong communication skills and an excellent work ethic. Expertise in (high-throughput) fluorescence imaging and analysis of RNA sequencing data are particularly welcome.

The Mennella lab is based at the MRC Toxicology Unit, an internationally renown institution focussed on the delivery of field-changing mechanistic insights into toxicology and disease. The Unit is equipped with state-of-the-art facilities including super resolution microscopy, a bioinformatics facility, mass spectrometry, advanced flow cytometry and offers excellent opportunities for postdoctoral development.

Applicants must hold a PhD in a relevant discipline such as molecular biology, cell biology and virology. The ability to work both independently and as part of a team, together with excellent communication and critical thinking skills are also essential.

Fixed-term: The funds for this post are available for 12 months with potential for follow up projects.

Interviews will be held in early January. Start date February, 2024.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

If you have any queries regarding the application process, please contact hradmin@mrc-tox.cam.ac.uk

Further information can be found on our website: https://www.mrc-tox.cam.ac.uk

Please quote reference PU39781 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs

Research Associates - Computational Biologist / Bioinformatician (Fixed Term)

Wed, 08/11/2023 - 00:00

The Patil lab at the MRC Toxicology Unit is looking to appoint two postdoctoral researchers to join their team.

We are a diverse team spanning multiple scientific disciplines, including microbiology, metabolomics, and bioinformatics. We are looking for two computational biologist / bioinformaticians to work on metabolism-centred modelling of microbial evolution and interactions. We are particularly interested in candidates enthusiastic for developing new tools for model-guided microbiome engineering.

The MRC Toxicology Unit offers excellent research infrastructure and support for personal development. Candidates will be encouraged to bring their own ideas to the project and learn new skills in, for example, metabolomics.

Candidates should have a PhD in a relevant discipline such as computational biology or metabolic engineering and have a strong research background in metabolic modelling. A good publication record in peer-reviewed journals is required.

Informal enquiries are invited and can be directed to Kiran R. Patil (kp533@mrc-tox.cam.ac.uk).

Relevant publications:

  1. Jouhten P., Konstantinidis D., Pereira F., Andrejev S., Grkovska K., Castillo S., Ghiachi P., Beltran G., Almaas E., Mas A., Warringer J., Gonzalez R., Morales P., Patil, K. R.. Predictive evolution of metabolic phenotypes using model¿designed environments. Mol Syst Biol 18:e10980 (2022)

  2. Konstantinidis, D., F. Pereira, E. M. Geissen, K. Grkovska, E. Kafkia, P. Jouhten, Y. Kim, S. Devendran, M. Zimmermann and K. R. Patil¿. Adaptive laboratory evolution of microbial co-cultures for improved metabolite secretion. Mol Syst Biol 17(8): e10189. (2021)

Fixed-term: These posts are funded for two years in the first instance. Further extension may be possible depending on the availability of funds.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

If you have any queries regarding the application process, please contact hradmin@mrc-tox.cam.ac.uk

Further information can be found on our website: https://www.mrc-tox.cam.ac.uk

Please quote reference PU39356 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs