Research Associate- Dupree Group (Fixed Term)
Applications are invited from an enthusiastic and team-oriented researcher to join the laboratory of Professor Paul Dupree. The Dupree lab https://www.bioc.cam.ac.uk/dupree is internationally recognised as a leading team of researchers in plant cell wall biochemistry. We aim to understand how the biosynthesis and assembly of polysaccharides generates the remarkable plant cell wall that can be strong, and resistant to decay or, when appropriate, able to expand as the cells grow. We apply our discoveries in applications from human and animal dietary fibre, gut microbiome modulation, soil health and synthesis of cellulosic materials to replace petrochemicals in packaging and building construction.
The successful candidate will join a team working to understand the relationship between glucomannan structure and function, in a project selected as an ERC Advanced grant to Prof Dupree, and funded by UKRI.
Candidates should hold a PhD (or be close to completion) in Biochemistry or other relevant field, with a strong background in plant or carbohydrate biochemistry. A proven track record of research productivity and the ability to lead diverse but complementary projects to completion is essential.
Experience in Arabidopsis molecular genetics such as CRISPR/Cas9, molecular biological techniques, protein expression, carbohydrate structural analysis or enzyme assays would be desirable.
Fixed-term: The funds for this post are available immediately until 30 September 2027 in the first instance.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Informal enquiries are welcome to be sent to Professor Dupree: pd101@cam.ac.uk
For queries regarding the application process, please contact: personnel@bioc.cam.ac.uk
Please quote reference PH45944 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Research Associate in Functional Metagenomics- novel biocatalysts for a sustainable circular economy from ultrahigh throughput screening- Hollfelder Group (Fixed Term)
A postdoctoral position is available for 12 months in the first instance, with a possible extension, from 1 June 2025, to work with Professor Florian Hollfelder at the Department of Biochemistry, University of Cambridge. (https://hollfelder.bioc.cam.ac.uk/). The project is part of the Horizon Europe project BlueTools (https://www.bluetools-project.eu/) and involves collaborations with various EU and UK groups on harnessing marine microbiomes and marine culture collections for novel biocatalysts that may play a role in future sustainable processes with higher resource and energy efficiency.
We will develop ultrahigh throughput assays to screen metagenomic libraries for new catalysts for applications in recycling, bioremediation and green chemistry. Candidate enzymes are mechanistically investigated, structurally characterised and subsequently improved by directed evolution. Ultrahigh-throughput screening in microfluidic picoliter droplets allows us to interrogate enzyme libraries with more than 10 million members experimentally in a day, increasing the chances of success in catalyst discovery.
Applicants should thus have a first (or upper second) class degree in chemistry, biochemistry or a related, relevant subject, followed by a PhD. Familiarity with molecular and chemical biology techniques and specific skills in assay development, enzyme kinetics, DNA library generation, structural biology, organic synthesis, high-throughput screening, mechanistic enzymology, database searching and microfluidic engineering are advantages, as well as postdoctoral experience. Applications should contain a description of research interests as part of the cover letter, a detailed CV (with exam marks and all relevant practical experience) and a list of publications. Please also include the names and email addresses of at least two referees, who are familiar with your research work.
Fixed-term: The funds for this post are available for 12 months starting 1st June 2025 in the first instance.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Informal enquiries are welcome to be sent to Florian Hollfelder: fh111@cam.ac.uk
For queries regarding the application process, please contact: personnel@bioc.cam.ac.uk
Please quote reference PH45939 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
IT Manager
The Department of Biochemistry, a large and flourishing academic community that enjoys a world-class reputation for both teaching and research, is embedded in the School of the Biological Sciences. Biochemistry, one of the largest Departments in the University, is based in two centrally located buildings housing around 500 staff and students. The Department houses a mix of laboratories, teaching and office space.
A new and exciting opportunity has arisen for an enthusiastic and efficient individual to join the Department in a management role, and take responsibility for the IT service and infrastructure
Based in a busy and friendly professional services team, and reporting to the Departmental Administrator & General Manager, the successful candidate will join a dynamic and dedicated team, taking responsibility for the creation of the IT vision of the Department and its delivery through a team of IT professionals.
Through a combination of project work and the delivery of day-to-day services, the role holder will ensure that IT creates the digital environment to enable the Department to fulfill its goals in research, teaching and learning, as well as providing the tools to support the delivery of the department's administrative functions.
This highly visible role supports, influences and delivers a wide range of facilities and interacts with colleagues at all levels. Other key contacts will be the University Information Service (UIS), the School of the Biological Sciences (SBS) and its departments, procurement and equipment providers.
The ideal candidate will be able to demonstrate significant experience in the definition, approach, facilitation and delivery of medium-scale projects. The successful candidate will show evidence of strong operational leadership in the design, procurement, installation, operation, maintenance, and effective use of IT infrastructure and its performance.
A working knowledge of a majority the following will be required: the design, maintenance and operation of [Windows, Mac, Linux, Android, iOS] clients, networking, relevant server environment/s, centralised authentication service/s, automated installation of OS and software deployment, virtualisation and web.
Applicants should be educated to degree level (or equivalent) and have significant technical and management experience in either higher education or a commercial environment.
The ideal candidate will also demonstrate excellent interpersonal skills, clear and concise communication and financial acumen. Experience in scientific computing, including high performance computing, would be beneficial.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Interviews are expected to be held during the week commencing 2nd June 2025.
Informal discussions are welcome; please contact the Departmental Administrator & General Manager, Dr Katherine Wallington (email: da@bioc.cam.ac.uk).
For further assistance, please contact the Biochemistry HR team via email: personnel@bioc.cam.ac.uk
Please quote reference PH45617 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Receptionist & Administrative Assistant (Secretriat)
The Department of Biochemistry, a large and flourishing academic community that enjoys a world-class reputation for both teaching and research, is embedded in the School of the Biological Sciences. An exciting opportunity has arisen for an enthusiastic and efficient individual to join the Department as Receptionist & Administrative Assistant - a key member of the Department's Secretariat team.
Based in a busy and friendly professional services team, and reporting to the PA to the Head of Department, the successful candidate will join a dynamic and dedicated team of reception, clerical and general administrative support specialists who work as a team to underpin the Department's performance and reputation as a modern, progressive academic teaching and research institution.
The successful candidate will provide a friendly and welcoming front-of-house service to staff, students and visitors to the Department of Biochemistry across its two main sites in Tennis Court Road at the Hopkins and the Sanger Buildings. Routine reception duties (responding to calls, distributing mail, issuing keys and access cards, supporting security and safety procedures etc.) are enhanced by the opportunity to explore a wider range of administrative tasks. These may include assisting with the support of departmental committee business, helping with general administrative tasks, and being involved in departmental event planning, organisation and promotion. There is plenty of opportunity and scope to excel in various areas of administrative support, allowing for the opportunity to hone and develop a diverse skill set.
Overall, this is an excellent opportunity for an enthusiastic individual to be central to the smooth running of departmental operations and governance by providing an efficient, friendly and 'can-do' front of house and administrative support service.
Educated to at least GSCE-level or equivalent, the ideal candidate will be able to work on their own initiative, be well organised in prioritising their work, be flexible in their approach and have excellent communication and IT skills along with a strong sense of team playing and working flexibly across a varied workload. They will have a strong understanding of the need for confidentiality, maintaining professionalism and discretion in all undertakings.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Interviews are expected to be held on Wednesday 14th May 2025.
Informal discussions are welcome; please contact the Departmental Administrator & General Manager, Dr Katherine Wallington (email: da@bioc.cam.ac.uk).
For further assistance, please contact the Biochemistry HR team via email: personnel@bioc.cam.ac.uk
Please quote reference PH45480 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Research Assistant - Godlee Group (Fixed Term)
We are seeking to recruit a research assistant to work for the laboratory of Camilla Godlee in the Department of Biochemistry at the University of Cambridge, UK. Research in the Godlee lab focuses on host-pathogen interactions of bacterial infections. https://www.godleelab.com/ https://www.bioc.cam.ac.uk/research/faculty/camilla-godlee
The position would suit an ambitious and talented graduate who has recently completed a degree in Molecular or Cellular Biology or Biochemistry and is keen to gain further laboratory research experience.
The key responsibilities of the post are assisting with research projects, contributing to laboratory organisation, maintenance of laboratory stocks, ordering of reagents, and managing chemical and biological waste. There will also be the opportunity to pursue an independent research project.
The ideal candidate will have a strong aptitude for scientific research, excellent communication skills, good time-management and organisational abilities. The ability to work well in a team is essential. Previous research experience in eukaryotic cell biology, flow cytometry, fluorescence microscopy, infection biology or microbiology would be highly desirable. Training will be provided as required.
Applicants should submit a CV citing relevant experience, a cover letter explaining why they are suitable for the position and contact information for at least two referees.
Fixed-term: The successful candidate would be expected to start at the beginning of October 2025. The funds for this post are available until 31 August 2026 in the first instance.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Informal enquiries are welcome to be sent to Camilla Godlee: cbjg2@cam.ac.uk.
If you have any queries regarding the application process, please contact: personnel@bioc.cam.ac.uk
Please quote reference PH45450 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Secretary & Receptionist (Secretariat)
The Department of Biochemistry, a large and flourishing academic community that enjoys a world-class reputation for both teaching and research, is embedded in the School of the Biological Sciences. A new and exciting opportunity has arisen for an enthusiastic and efficient individual to join the Department as a Secretary & Receptionist - a key member of the Department's Secretariat team.
Based in a busy and friendly professional services team, and reporting to the PA to the Head of Department, the successful candidate will join a dynamic and dedicated team of reception, clerical and general administrative support specialists who work as a team to underpin the Department's performance and reputation as a modern, progressive academic teaching and research institution.
The successful candidate will provide a full secretarial service to departmental academics and/or senior management and will take an active role on reception in the Department's two buildings on a rotational basis. This is a key role in support of the smooth and efficient operation of the Department's work and time.
The successful candidate will contribute to the committee work of the Department and be central to the smooth running of operations and governance by providing an efficient, friendly and 'can-do' secretarial and reception service. Due to the nature of the role, the position is office-based, Monday to Friday.
Educated to at least A-level or equivalent, the ideal candidate will be experienced in administrative office work and have a clear understanding of general reception and secretarial responsibilities, along with a strong sense of team playing and working flexibly across a varied workload.
Fixed-term: The funds for this post are available for 3 years in the first instance.
Applications are welcome from internal candidates who would like to apply for the role on the basis of a secondment from their current role in the University.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Interviews are expected to be held on Monday 12th May 2025.
Informal discussions are welcome; please contact the Departmental Administrator & General Manager, Dr Katherine Wallington (email: da@bioc.cam.ac.uk).
For further assistance, please contact the Biochemistry HR team via email: personnel@bioc.cam.ac.uk
Please quote reference PH45464 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Research Associate - Pellegrini Group (Fixed Term)
Applications are invited for a Research Associate position in the laboratory of Professor Luca Pellegrini, in the Department of Biochemistry, University of Cambridge.
Work in the laboratory is focused on elucidating the structural basis for eukaryotic DNA replication (Rzechorzek et al, NAR, 2020; Evrin et al, EMBOJ, 2018; Villa et al, Mol Cell, 2016; Simon et al, Nat Comm, 2016; Simon et al, Nature, 2014) and associated DNA repair processes (Hanthi et al, Mol Cell, 2024; Appleby et al, Nat Comm, 2023; Lerner et al, EMBOJ, 2020; Brouwer et al, EMBOJ, 2018).
The aim of the project is to elucidate key molecular mechanisms of DNA synthesis by the human replisome, the dynamic multi-protein ensemble responsible for duplicating chromosomal DNA before cell division. To achieve this goal, the successful candidates will use a multi-disciplinary approach that includes preparative biochemistry of multi-protein complexes, protein engineering and state-of-the-art biophysical and structural techniques.
The project will advance our understanding of how our cells copy their DNA and thus maintain genomic stability across cellular generations. In addition to its biological importance, such information will have great medical relevance, as disease such as cancer and premature aging are promoted by errors in our genome caused by defective replication.
Applicants should submit a CV with list of relevant publications, a cover letter explaining why they are suitable for the position and contact information for at least two referees.
Fixed-term: The funds for this post are available until 31 May 2026 in the first instance.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Informal enquiries are welcomed and should be directed to Professor Luca Pellegrini via: lp212@cam.ac.uk
If you have any queries regarding the application process, please contact: personnel@bioc.cam.ac.uk
Please quote reference PH45305 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Research Associate (Bonfio) (Fixed Term)
We are seeking to recruit a postdoctoral research associate to work on a new project in the laboratory of Claudia Bonfio in the Department of Biochemistry at the University of Cambridge, UK.
The project will push the bounds of early Earth lipid chemistry, exploring pathways by which the vast array of diverse lipids now associated with biological membranes came into being.
Research in the Bonfio lab focuses on the chemical origins and properties of early lipid membranes and compartments (www.bonfiolab.eu).
The key responsibilities of the post will be conducting an independent research project, assisting with projects ongoing in the lab, and contributing to lab organisation and general lab duties.
Fixed-term: The funds for this post are available for 1 years in the first instance.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Informal enquiries are welcomed and should be directed to Dr Claudia Bonfio via: cb2036@cam.ac.uk
If you have any queries regarding the application process, please contact: personnel@bioc.cam.ac.uk
Please quote reference PH45191 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Research Laboratory Technician (Fixed Term)
Cambridge Centre for Proteomics core facility is currently looking to recruit a Research Laboratory Technician to perform sample preparation from user samples.
The successful candidate will be required to perform routine proteomics sample preparation (run SDS-PAGE gels, in-gel digestion, solution digestion, protein/peptide estimations, and employ sample clean-up techniques). They will also need to collect and log samples, perform routine health and safety tasks, maintain equipment and order lab consumables. The role-holder will be an integral member of CCP and will need to interact closely with other members of CCP and internal and external users of the service to provide help and guidance with sample preparation.
The role holder will have first degree in biochemistry, biology, chemistry or a related subject.
Fixed-term: The funds for this post are available for 3 years in the first instance.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Informal enquiries are welcomed and should be directed to Dr Mike Deery via: md289@cam.ac.uk
If you have any queries regarding the application process, please contact the Biochemistry HR Team: personnel@bioc.cam.ac.uk
Please quote reference PH45160 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
