Research Assistant (Fixed Term)
The Functional Genomics Screening Laboratory (FGSL) is seeking a highly motivated research assistant with broad skills in molecular and cellular biology.
About the FGSL:
The FGSL is a partnership between the Milner Therapeutics Institute (MTI), the Medical Research Council and AstraZeneca. The newly established lab, located in the MTI, aims to accelerate novel target discovery in health and disease through CRISPR screening. Leveraging arrayed screening to systematically perturb individual genes in a microtitre plate format, the FGSL forms cross-functional partnerships to interrogate the genome at scale. The lab aligns with the MTI's vision of breaking the mould of how academia and industry interact. The FGSL is part of the UK Research and Innovation's Human Functional Genomics Initiative, aiming to facilitate innovative and collaborative research to drive new scientific discoveries.
Key responsibilities:
The post holder will support a diverse range of arrayed CRISPR screening projects in non-oncology research areas. Working closely with our team of wet and dry lab scientists, the successful applicant will utilise their molecular and cellular biology skills to support CRISPR screening experiments. Typical tasks will include culturing human cellular models, such as primary cells, stem cells, co-cultures or organoids; assisting the run of high-throughput screening; and supporting the operations of the labs.
Why join us?
The MTI offers a buoyant, vibrant, and fast-paced environment that fits individuals who thrive amidst change and innovation. You will work at the dynamic interface between academia and industry, engaging with researchers from diverse sectors to foster knowledge exchange and drive pioneering functional genomics research.
We welcome applications from BSc and MSc graduates with an adaptive mindset, who are eager to learn and are interested in playing a supportive role to help the team to achieve goals. You will be part of an engaging and supportive environment that prioritises professional growth and career development. The role offers the unique opportunity to be involved in a variety of screening projects and will equip the successful applicant with transferable skills in the field of functional genomics, as well as laboratory operations.
Additional information:
Fixed-term: The funds for this post are available for 3 years in the first instance.
Application process:
To find out the full duties of the role and person specification, click below to view the further particulars.
In person interviews will be held between 21st and 31st July 2025.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Informal enquiries can be directed to Chun Hao Wong, FGSL lead, wc389@cam.ac.uk
Please quote reference PR46151 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Research Associate x 2 (Fixed Term)
The Functional Genomics Screening Laboratory (FGSL) is seeking two research associates to perform high-throughput CRISPR phenotypic screening in complex models.
About the FGSL:
The FGSL is a partnership between the Milner Therapeutics Institute (MTI), the Medical Research Council and AstraZeneca. The newly established lab, located in the MTI, aims to combine know-how and experience to accelerate novel target discovery in health and disease. Leveraging arrayed screening to systematically perturb individual genes in a microtitre plate format, the FGSL forms cross-functional partnerships to interrogate the genome at scale. The lab aligns with the MTI's vision of breaking the mould of how academia and industry interact. The FGSL is part of the UK Research and Innovation's Human Functional Genomics Initiative, aiming to facilitate innovative and collaborative research to drive new scientific discoveries.
Key responsibilities:
Working closely in a team, the post holder will design and implement arrayed CRISPR screens in human cellular models. This will include primary cells, stem-cells, co-cultures or organoids in non-oncology research areas. Working with academic and industry collaborators across the UK, the successful candidate will scope and optimise a range of functional assays such as high-content imaging, flow cytometry or ELISAs to characterise the phenotypic changes upon CRISPR editing. The role will involve designing and performing high-throughput screening workflows that encompass gene editing, phenotypic assays and automated liquid handlers.
Why join us?
The MTI offers a buoyant, vibrant, and fast-paced environment that fits individuals who thrive amidst change and innovation. As part of our team, you will work at the dynamic interface between academia and industry, engaging with researchers from diverse sectors to foster knowledge exchange and drive pioneering functional genomics research.
You will be part of an engaging and supportive environment that prioritises professional growth and career development. The role offers the unique opportunity to enhance a variety of transferable scientific skills such as culturing and perturbing complex cell models, applying laboratory automation in biological experiments, and analysing multi-parametric data to support phenotypic-driven target discovery.
Application process:
To find out the full duties of the role and person specification, click below to view the further information document.
Interviews will be held in-person between the 21st-31st July.
Additional information:
Fixed-term: The funds for this post are available for 3 years in the first instance.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Informal enquiries can be directed to Chun Hao Wong, FGSL lead, wc389@cam.ac.uk
Please quote reference PR46150 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
