Job opportunities at Gurdon and Milner Therapeutics Institutes

An exciting opportunity has arisen for a Facilities Manager to join our busy operations team which manage building, equipment and centralised activities in support of existing and upcoming research in the Institute. Recently, the Gurdon Institute has refocused its research direction, creating a Human Developmental Biology Hub within the School of Biological Sciences. This shift brings exciting new scientific talent to our community, and we need an enthusiastic, motivated individual to help integrate these groups and support their cutting-edge work.

As Shared Facilities Manager, you will: -Lead and oversee our shared tissue culture facilities and core scientific equipment with responsibility for procuring equipment and maintenance/service agreements. -Provide essential support for centralised activities and help maintain our research infrastructure. -Liaise with research groups, fostering collaboration and ensuring our researchers have the tools they need to excel. -Work as part of a small facilities team within a wider team of professional staff. You are: -Educated to degree level or equivalent, with extensive tissue culture experience. -A problem-solver who is adaptable, flexible, and responsive to the evolving needs of a dynamic research environment. -A team player with the confidence to ask questions, help out and take the lead when needed. -Knowledgeable and curious, familiar with biological research equipment and eager to master new technologies. -Familiar with health and safety regulations. -A natural communicator, able to engage with a wide range of professional and research staff, visiting academics and students.

The position is offered on a permanent, full-time basis, though we also welcome applications from individuals who wish to be considered for slightly less than full time hours. Although there may be flexibility over working hours, the role requires you to work onsite most of the time (Tennis Court Road, central Cambridge).

Why Join Us? This role places you at the centre of our mission, ensuring that as research directions evolve, we remain agile and equipped to support new scientific needs. This is your chance to play a pivotal role in the shaping of a new chapter in the life of this globally renowned institute.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please quote reference PR44715 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

This is an exciting new opportunity for a Research Assistant to join the Milner Therapeutics Institute Target Discovery Team, led by Dr Erica Bello.

The research of the Target Discovery Team focuses on the development and application of CRISPR screening technology to complex human in-vitro models of disease, aimed at identifying novel therapeutic targets.

The Milner Therapeutics Institute (MTI) is a purpose-built research institute at the University of Cambridge, and its overarching vision is to transform pioneering science into therapies. The MTI is breaking new ground in academic/business interactions and demonstrates a world-leading model of start-up companies, academics and pharma working side by side at the bench. The MTI environment offers a unique opportunity to work at the interface of academia and business, applying ground-breaking technologies to drug discovery and patient treatment.

The Research Assistant role will provide experimental support to researchers within the MTI's Target Discovery Team to help deliver projects aligned with the objectives of the Milner Institute. They will utilise molecular biology and tissue culture techniques, such as cloning, genotyping, CRISPR/Cas9 editing, CRISPR screening and cell differentiations, to assist researchers and develop novel experimental workflows.

The necessary training will be provided, and this role is a great opportunity to develop new laboratory skills to apply in a cutting-edge research environment. In addition to experimental support, the role will involve tasks related to maintenance and general running of the laboratory.

The role holder should hold (or be about to obtain) an Undergraduate or Masters degree in a relevant subject such as genetics, molecular biology, biomedical or biological sciences or biochemistry. They should also have practical experience in molecular biology and knowledge of research techniques, including a critical understanding of relevant theory and principles.

For the full requirements of the position, please read the further particulars by following the link below.

Interviews will be held in-person on the 26th, 27th and 28th February.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries can be directed to Dr Erica Bello eb956@cam.ac.uk

Please quote reference PR44711 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

A rare and exciting opportunity has arisen to join our busy and friendly research institute as a HR Administrator. The Gurdon Institute is a department of the University of Cambridge at the cutting edge of science, with 12 research groups, carrying out research on projects related to cancer and developmental biology.

We are looking for a friendly, flexible and enthusiastic team player, who is willing to learn and develop as part of a wider group of friendly and highly skilled professional services staff. If you think that describes you then this is an amazing opportunity to gain experience in a skilled environment, apply today or contact hr@gurdon.cam.ac.uk for an informal discussion about the role.

Main duties will include:

-Acting as first point of contact for HR-related queries.

-Providing HR administrative support.

-Updating HR systems for recruitment, sickness, annual leave, probation, staff reviews, staff records etc.

-Completing HR paperwork as required.

-Organise inductions for new members of the Institute.

-Setting up visitor agreements.

-Acting as secretary for the Wellbeing, Inclusivity, Diversity and Equality Committee.

-Provide cover for the reception team when required.

Essential skills for this post are:

-Educated to GCSE level or have equivalent practical experience.

-Previous HR administrative experience and be used to dealing with confidential information.

-Excellent communication and organisational skills.

-Competent user of Microsoft Office.

-High level of accuracy and attention to detail.

-Be able to communicate effectively with a range of colleagues across the Institute.

-Knowledge of university HR systems would be an advantage

Benefits of working at Cambridge include:

-Automatic pay progression and annual cost of living increases.

-Generous annual leave allowance of 36 days paid leave (including bank holidays) for full time employees.

-Generous maternity, adoption and shared parental leave entitlement and other family friendly schemes.

-An auto-enrolment pension scheme, with a generous employer contribution.

-Travel benefits and retail discounts at over 2,000 local and national stores.

The position is full time and it is available immediately.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please quote reference PR44597 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

The Strategic Partnership Manager is a brand-new role at the Milner Therapeutics Institute and an exciting opportunity for a motivated individual to lead the overall strategy and delivery of a new partnership between the Milner Therapeutics Institute, Cambridge University Health Partners (CUHP) and Flagship Pioneering.

The Milner Therapeutics Institute (MTI) is a purpose-built research institute at the University of Cambridge, with an overarching vision to convert pioneering science into therapies by driving academic¿industry partnerships. The MTI is breaking new ground in academic¿industry interactions and demonstrates a world-leading model of start-up companies, academics and pharma working side by side at the bench.

The Strategic Partnership Manager will act as a conduit between researchers across Cambridge and Flagship Pioneering companies, working closely with the Flagship Global Engagement team to align company challenges and priorities for external collaboration with academic and clinical expertise in Cambridge. They will devise and deliver a programme of events to faciliate introductions and create opportunity for new partnerships. They will support the initiation of these partnerships (e.g. through coordination with the Research Operations Office, Cambridge Enterprise and CUH), including research collaborations, consulting agreements, clinical trial facilitation as well as new projects with Flagship Pioneering, leveraging expertise and capabilities from the University, Research Institutes or NHS Trusts.

The role holder will need a PhD in biomedical science or equivalent. They will have experience in scientific project and business partnership management, including interdisciplinary research projects, and an ability to identify projects that are innovative and more likely to be of strong interest to external partners. For the full person specification, please follow the below link to the further particulars before applying.

Flagship Pioneering invents and builds bioplatform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $60 billion in aggregate value. Flagship's ambition is to create multiple high-impact companies through cutting-edge scientific exploration. Flagship has recently extended its presence and connections beyond its home base in Boston, USA to the UK. A notable step in this direction was the establishment of Quotient Therapeutics, the first Flagship company based outside the USA.

Cambridge University Health Partners (CUHP) aims to facilitate global investment and attract talent into the Cambridge ecosystem bringing together its members (Cambridge University, Anglia Ruskin University, Cambridge University hospitals, Cambridge and Peterborough Foundation Trust, Royal Papworth) alongside the life science companies and local authorities. CUHP's mission to improve health globally by supporting discovery of breakthrough innovations, rapid demonstration in real world populations and delivery of fabulous healthcare and economic growth aligns perfectly with Flagship's goal of expanding its global footprint and fostering international collaborations.

Fixed-term: The funds for this post are available for 1 years in the first instance.

Applications are welcome from internal candidates who would like to apply for the role on the basis of a secondment from their current role in the University.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries can be directed to Alison Schuldt, Head of Partnerships and Alliance, ajs52@cam.ac.uk.

Please quote reference PR44519 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

We are looking for a highly motivated post-doctoral scientist and a lab manager to join the laboratory of Dr. Sumru Bayin at the Gurdon Institute, and the Department of Physiology, Development and Neuroscience at the University of Cambridge. You will work in the Bayin Lab to explore the molecular mechanisms of neural stem cell behaviours during cerebellum development and upon injury using various techniques including but not limited to single cell genomics, and in vivo and in vitro stem cell assays, organoid models and mouse genetics.

The Bayin Lab is interested in identifying the molecular mechanisms that regulate self-renewal, differentiation and plasticity of neural stem/progenitor populations during development and homeostasis, in order to discover how to stimulate repair of the brain upon injury. The cerebellum, which is a folded hindbrain structure that is important for skilled motor movements and higher order cognitive functions, has emerged as a powerful system to study the regenerative responses in the brain. We have previously shown that the cerebellum can recover from the loss of at least two types of neurons via distinct regenerative mechanisms (Wojcinski, Nature Neuroscience, 2017; Bayin, eLife, 2018; Bayin, Science Advances, 2021, Bayin and Joyner, Development, 2022). However, the full repertoire of molecular and cellular mechanisms that regulate neonatal cerebellar development and injury response remain to be studied. Importantly, the regenerative potential of the neonatal cerebellum dramatically decreases once development ends, despite the presence of stem-like cells in the adult mouse cerebellum. This project involves using in vivo and in vitro approaches to identify mechanisms that control the developmental and regenerative responses of cerebellar progenitors in neonates and determine how it differs in adults in order to understand how we can facilitate efficient repair after injury to the brain. A variety of other projects on neural stem cell biology during brain development and pathologies are possible, depending on the candidate's interest and background.

Applicants must have (or expect to obtain) a PhD (or equivalent) in biological sciences, preferably in cell, developmental biology or in genetics. A strong background in molecular biology, stem cell biology and an interest in bioinformatics is required for the postdoctoral research post, and experience in genetics and in vivo models is desired. The lab manager is expected to do ordering, mouse colony management, lab organisation and maintenance, in addition to helping others with their projects when needed. Experience in histology, cell culture and molecular biology is required.

Importantly, we are looking for a highly motivated and enthusiastic team member who is a critical thinker, can work independently and has excellent communication skills with the ability to work collaboratively within and outside of the laboratory and promote a positive research culture within the laboratory.

Successful candidates who have not been awarded their PhD by the appointment date will be appointed as a Research Assistant at Grade 5 (£33,882-£34,866 per annum). Upon award of the PhD the individual will be promoted to Research Associate, Grade 7 (£36,924-£45,163 per annum).

Fixed-term: The funds for this post are available until 31 December 2026 in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please quote reference PR44275 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

This is a new role at the Milner Therapeutics Institute (MTI) within the Computational Biology and Artificial Intelligence (AI) group.

The Milner Therapeutics Institute (MTI) is a purpose-built research institute at the University of Cambridge. The overarching vision of the MTI is to transform pioneering science into therapies. The MTI is breaking new ground in academic/business interactions and demonstrates a world-leading model of start-up companies, academics and pharma working side by side at the bench. The MTI environment offers a unique opportunity to work at the interface of academia and business, applying ground-breaking technologies to drug discovery and patient treatment.

In partnership with the Korean Research Institute of Bioscience and Biotechnology (KRIBB), the MTI is engaged in an ambitious AI-based drug screening project aimed at supporting gene and cell therapy advancements. This collaborative project will leverage AI to develop screening tools for gene therapy vector materials, build a comprehensive digital bank of these materials, and predict transcription and translation processes to enhance gene therapy efficiency. This project presents an exceptional opportunity to work at the interface of computational biology and biopharmaceutical development.

The role holder will need to hold a Master's degree in bioinformatics, computational biology, biology, or a related scientific discipline. They should have foundational knowledge in computational analysis of biological or clinical data, and the ability to work collaboratively and communicate effectively within a multidisciplinary team. The full role specifications can be found in the Further Particulars document.

Please follow the below link to read the full person specification in the Further Particulars before applying.

Fixed-term: The funds for this post are available for 2 years in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries can be directed to Dr Namshik Han Head of Computational Biology and Artificial Intelligence, nh417@cam.ac.uk.

Please quote reference PR44235 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate in CRISPR phenotypic screening

The Milner Therapeutics Institute (MTI) at the University of Cambridge aims to accelerate translation of pioneering science into therapies. The newly established Functional Genomics Screening Laboratory (FGSL) at the MTI applies arrayed CRISPR screening in human cellular models to advance mechanistic understanding underlying tissue homeostasis and disease biology. Formed as a joint venture with the Medical Research Council and AstraZeneca, this new laboratory aligns with the MTI's vision of breaking the mould of how academia and industry interact. The FGSL is part of the UK Research and Innovation's Human Functional Genomics Initiative to facilitate innovative and collaborative research to drive new scientific discoveries.

We are seeking to recruit a biologist interested in phenotypic screening to join the FGSL team. You will be applying your expertise in characterising complex models such as stem cells, organoids, primary cells and co-cultures to design and implement arrayed CRISPR screens. The ideal candidate is proficient in developing a range of functional assays such as imaging and flow cytometry to identify key phenotype suitable for high-throughput screening. Previous experience in utilising automated or semi-automated liquid handlers for microplate-based assays is highly desirable.

This is a highly collaborative role where you will work closely with scientists and bioinformaticians from the MTI, AstraZeneca, small/medium enterprises and academic institutions. You will have the opportunity to develop new skills in areas including multi-modality screens, automation platform and bioinformatics analysis.

The MTI is a buoyant, vibrant and fast-paced environment and is ideal for those who thrive in the face of change. We welcome applications from recent PhD graduates or experienced postdocs that are enthusiastic to work as part of a dynamic team at the interface between academia and industry. We offer an engaging and supportive environment that fosters professional growth and career development.

To find out the full duties of the role and person specification, click below to view the further particulars.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries can be directed to Chun Hao Wong, FGSL lead, wc389@cam.ac.uk.

Please quote reference PR43930 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate in high-content imaging

The Milner Therapeutics Institute (MTI) at the University of Cambridge aims to accelerate translation of pioneering science into therapies. The newly established Functional Genomics Screening Laboratory (FGSL) at the MTI applies arrayed CRISPR screening in human cellular models to advance mechanistic understanding underlying tissue homeostasis and disease biology. Formed as a joint venture with the Medical Research Council and AstraZeneca, this new laboratory aligns with the MTI's vision of breaking the mould of how academia and industry interact. The FGSL is part of the UK Research and Innovation's Human Functional Genomics Initiative to facilitate innovative and collaborative research to drive new scientific discoveries.

We are seeking to recruit a scientist with experience in high-content imaging, both in the wet and dry lab, to join the FGSL team. You will be applying your expertise to design, implement and interpret arrayed CRISPR screens with imaging as well as other phenotypic endpoints. The ideal candidate will be proficient in a range of imaging assays such as fixed or live imaging, Cell Painting, and RNA imaging to identify key phenotype suitable for high-throughput screening. Previous experience in characterising complex models such as 3D or co-cultures using microscopy approaches is desirable. Programming experience in processing and analysing bioimage data is highly desirable.

This is a collaborative role where you will work closely with scientists and bioinformaticians from the MTI, AstraZeneca, small/medium enterprises and academic institutions. You will have the opportunity to develop new skills in areas including multi-modality screens, automation platform and complex model culture.

The MTI is a buoyant, vibrant and fast-paced environment and is ideal for those who thrive in the face of change. We welcome applications from recent PhD graduates or experienced postdocs that are enthusiastic to work as part of a dynamic team at the interface between academia and industry. We offer an engaging and supportive environment that fosters professional growth and career development.

To find out the full duties of the role and person specification, click below to view the further particulars.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries can be directed to Chun Hao Wong, FGSL lead, wc389@cam.ac.uk.

Please quote reference PR43931 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

A rare and exciting opportunity has arisen to join our busy and friendly research institute as a Finance/Accounts Assistant. The Gurdon Institute is a department of the University of Cambridge at the cutting edge of science, with 12 research groups, carrying out research on projects related to cancer and developmental biology.

We are looking for a friendly, flexible and highly numerate Finance/Accounts Assistant to join our Admin team. The successful candidate will have excellent organisational skills and experience of working in an accounts and ideally laboratory-based environment. Experience of working with research grants, would also be desirable. As the role involves liaising with members of the Institute at all levels and occasionally external agencies and sponsors, in addition to acting as a point of contact for financial queries, it is essential that you have excellent communication skills. You should be able to work as part of a team but also to work independently. Knowledge of university finance systems would be an advantage, to enable you to provide cover for the team during holidays of other team members.

We are seeking an enthusiastic team player, who is willing to learn and develop as part of a wider group of friendly and highly skilled professional services staff. If you think that describes you then this is an amazing opportunity to gain experience in a dynamic and skilled environment, apply today or contact hr@gurdon.cam.ac.uk for an informal discussion about the role.

Duties will include:

• Acting as first point of contact for finance enquiries.
• Raising and processing invoices and expense claims.
• Reconciling credit card statements.
• Running and reviewing UFS reports and issuing the information to grant holders.
• Acting as a point of contact for financial matters within the Institute.
• Maintaining, filing and archiving financial records and databases.
• Credit controlling of month end procedures.
• Providing cover for Stores and purchasing team.

Essential skills for this post are:

• Educated to GCSE level or have equivalent practical experience.
• Experience using Microsoft Office, particularly Excel.
• High level of accuracy and attention to detail in your work.
• Be able to communicate effectively with a range of colleagues across the Institute.

The position is permanent and available immediately.

We welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please quote reference PR43842 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.