http://www.jobs.cam.ac.uk/job/?unit=u00269&format=rss

We are inviting applications for a curious and motivated Postdoctoral Scientist (Research Associate) to join the de Hoz lab at the Department of Physiology, Development and Neuroscience. The de Hoz lab investigates systems neuroscience questions, specifically the role of cortico-subcortical loops in statistical learning. We focus on the auditory system and perform awake/asleep electrophysiology recordings (Neuropixels) and behaviour in mice, while assessing their mental state. We ask questions such as how are noisy sensory inputs recognized and represented in the brain? how are dynamic texture sounds (waterfall, fire) represented? What is the role of corticofugal projections in setting expectations? How does the auditory system integrate information over time? How does representation change with mental state (aroused, asleep, groggy)? We are a small, supportive, and dynamic group (www.dehozlab.org) made of a diversity of people united by a passion for science and the brain. The lab is now transitioning to the University of Cambridge, where this post will be held. We are looking for a person to perform the experiments and help setup the lab at PDN. This vibrant and interactive department spans systems neuroscience and plasticity questions, and is imbedded in the wider Cambridge neuroscience environment.

The key ingredient is to be passionate about the questions of the lab, to be independent, and a background in systems neuroscience. Ideally you would have experience with mouse behaviour and/or Neuropixels recordings and analysis, as well as with opto/chemogenetics. Being a pro with Python/MatLab helps.

Please refer to the further particulars document for a full list of the essential knowledge, skills and experience required for the role.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

To apply for this post, please submit a CV, a motivation letter detailing why you want to be part of this project and how this post will be a good stepping-stone for your career. We also need the contact details for two people who can provide a professional reference.

Informal enquiries about the position can be made to Livia de Hoz (ld749@cam.ac.uk and livia.dehoz@charite.de). If you feel that you don't have all necessary skills but are very interested in the research, please contact me.

Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will be appointed at Research Assistant level, which will be amended to Research Associate once the PhD has been awarded.

The funds for this post are available for 20 months, starting between October 2025 and March 2026.

The closing date for applications is 31st July 2025.

Please quote reference PM45891 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

The Department of Physiology, Development and Neuroscience is seeking to appoint a self-motivated, enthusiastic person to join our friendly Human Anatomy Centre team. The facility delivers first and second year anatomy and neuroanatomy courses to an intake of around 320 pre-clinical medical students each year, and supports both research projects and external courses for a wide range of medical professionals. This is an exciting opportunity for someone looking for an interesting and varied role within a busy teaching environment.

Reporting to the Human Anatomy Centre Manager, and working closely with the University Clinical Anatomists and the organisers of preclinical anatomy and neuroanatomy, the role-holder will provide valuable support to help ensure the smooth running of the Centre. Duties will be diverse and will include providing administrative support to the anatomy Course Organisers, as well as the body donation programme in the Centre.

The successful candidate will have excellent communication skills, with the ability to deal professionally and efficiently with enquiries from students, colleagues, bereaved relatives and medical professionals, and will work well in a small and inclusive team. They will also be highly organised and have a flexible approach to work, with an ability to move between tasks at short notice to meet deadlines. Proficiency in Microsoft Office and the ability to manage databases of sensitive and confidential data is also essential. Familiarity with medical terminology would be useful, but training in the work of the Centre will be provided, and a lack of directly related experience is not a bar to applying.

The appointment is offered on a permanent, full-time basis, though we also welcome applications from individuals who wish to be considered for part-time working (minimum 25 hours per week, over five days).

For informal enquiries please contact the Department's HR team at pdnhr@pdn.cam.ac.uk who will be happy to direct your enquiry.

Apply:

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

On the online form, in the suitability for the role section, you should explain the reasons for your application and how your knowledge, skills and experience match the requirements of the role. The full contact details for two professional referees should be provided; one of whom should be your current line manager. Please note that we will assume that you are happy for us to approach your referees at any stage, unless you indicate otherwise in the space provided on the form.

Closing date: Wednesday 21 May 2025.

Interviews will be held in person on Wednesday 4 June.

Please quote reference PM45845 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Applications are invited from an enthusiastic and highly motivated researcher to join the laboratory of Prof Amanda Sferruzzi-Perri. The Sferruzzi-Perri lab (https://www.pdn.cam.ac.uk/directory/amanda-sferruzzi-perri) focuses on understanding the aetiology of pregnancy complications and the regulation of developmental processes in a broader physiological and environmental contexts. The lab employs integrative approaches combining environmental mouse models and human pregnancy samples with cutting edge molecular, cellular and physiological techniques.

The successful candidate will join a collaborative multidisciplinary team investigating how placental development and function contribute to adverse pregnancy outcomes in cases affected by hypoxia or elevated heat exposure.

Candidates should hold a PhD (or be close to completion) or a first degree in a relevant field, with a strong background in pregnancy or developmental physiology research. A proven track record of research productivity and the ability to lead diverse but complementary projects to completion is essential.

Experience in in vivo experimentation with rodents, RNA sequencing (or other high-throughput technologies), bioinformatic analysis, and the handling of large datasets is essential. Proficiency in ex vivo tissue analysis, cell and organoid culture, and gene targeting (e.g., CRISPR/Cas9) is highly desirable. Additional experience in animal husbandry, possession of a Home Office Personal Licence, and handling of human clinical samples would be advantageous.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Applications should include a personal statement highlighting suitability to the post, detailed CV and the names and addresses of two academic referees. The position is available from September 2025 for 18 months in the first instance.

The closing date for applications is 30th May 2025.

For further details, please email Prof Sferruzzi-Perri at: ans48@cam.ac.uk.

Please quote reference PM45843 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

The GOdogs group is looking to appoint researcher to our group which studies the genetics of obesity, starting with canine genetics but with a strong programme of allied human comparative genetics and functional/molecular studies.

Whilst the focus of this recruitment drive is to find a candidate with genomics expertise, enquiries would also be welcome from molecular biologists interested in using their skills to pursue functional studies of new obesity genes (especially related to endocytosis and cell signalling).

We use GWAS and genetic approaches to identify novel genes responsible for obesity and other common conditions in pet dogs, then use comparative genomics to determine those genes also relevant to humans. Genes and variants responsible are studied in the molecular biology lab and by testing their effect on the physiology and eating behaviour of dogs. All our canine work is done with pet dogs, volunteered by their owners for study (not dedicated lab animals).

This post will be focussed on the genetics of appetite and obesity. Candidates should be of postdoctoral level with relevant experience of canine or/and human genomics, or molecular biology. Candidates without PhD but significant expertise in bioinformatics and genetics would also be considered.

For genetics-focussed candidates, subject knowledge in obesity/metabolism is welcome, but not essential. For molecular biology candidates, background knowledge relevant to understanding the molecular links between genes and obesity is more important.

We are a small group with diversity of background, interest and experience in which wider professional development and pursuit of your interests are encouraged alongside scientific rigour and excellence.

Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will be appointed at Research Assistant level, which will be amended to Research Associate once the PhD has been awarded.

Informal enquiries can be made to Dr Eleanor Raffan er311@cam.ac.uk. Candidates interested in part time or flexible working are encouraged to discuss this in advance of application.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

To apply for this post, please submit a CV and a covering letter detailing why you want to be part of this project and how this post will be a good stepping-stone for your career. We also need the contact details for two people who can provide a professional reference.

The closing date for applications is 26th May 2025.

Please quote reference PM45840 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Next Generation Fellow, Centre for Trophoblast Research

The Loke Centre for Trophoblast Research (CTR) was founded in 2007 as a Centre of excellence to promote scientific study of the placenta, early development and maternal-fetal interactions during pregnancy. It brings together over 30 Principal Investigators, many of whom are recognized international experts in their fields.

The Loke CTR has an opening for a Next Generation Fellow who will complement and synergise with our existing research programmes. Next Generation Fellowships are a springboard to a long and successful career in the field of placental and reproductive biology and highly flexible to suit individual needs, to enable the postholder to develop as an independent researcher. Holders are expected, and will be supported, to apply for Research Fellowship/Career Development Awards from research councils or other funders, or a faculty position during their tenure. Find out more about the fellowship on our website: https://www.trophoblast.cam.ac.uk/ngf-overview

The Next Generation Fellowships are a springboard to a long and successful career in the field of placental and reproductive biology. Many of our Next Generation Fellows have used the opportunity as a stepping stone to independent group leader positions: https://www.trophoblast.cam.ac.uk/next-generation-fellow-alumni.

What to expect

Next Generation Fellows will be mentored to develop and establish an independent research program that will complement that of other groups within the Centre for Trophoblast Research. Fellows will be expected to contribute fully to the activities of the Loke CTR and to their host department. They will supervise MPhil/masters, summer and/or undergraduate students. They may be a co-applicant on research grant applications to recruit, train and co-supervise postdoctoral researchers, research assistants, technical staff and PhD students.

The post holder will be expected to create a strong track record of publishing high impact papers and disseminate the results of their work in any ways that seem appropriate and effective (e.g. via conferences and seminars). They will be responsible for compliance with all the relevant laws (Home Office, HTA, HFEA).

Candidates should hold a PhD and have a high-quality publication track record in academic journals or equivalent. We welcome applications from across a diverse range of research relevant to our Grand Challenges https://www.trophoblast.cam.ac.uk/about-us/objectives.

Contract details

Appointments will be made on a fixed-term, full-time, basis for a period of 3 years (Grade 7, £37,174- £45,413 for appointments in 2025). There is a possibility of up to 1-year extension. The contract further includes research consumables/equipment of £60,000 per annum & travel support up to £750 over the duration of the fellowship.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

To apply to this post, candidates should first identify a research Sponsor from the list of Principal Investigators https://www.trophoblast.cam.ac.uk/people/principal-investigators within the Centre for Trophoblast Research, and discuss their research plans with them.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

In addition to this, please ensure that you upload the application documentations as follows:

• Curriculum Vitae (CV)

• Up to 3 letters of reference

• Letter of support from your chosen Loke CTR sponsor

• Loke CTR Next Generation Fellowship application form

The closing date for applications is 30th January 2026.

Please quote reference PM45775 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

The Department of Physiology, Development and Neuroscience (PDN) is seeking a Grants Assistant to support the Department's research groups. PDN is a large, welcoming, and inclusive Department with an exceptional international record in teaching and research, with a grant income in the order of £10 million annually.

Reporting to the Research Grants Administrator, the Grants Assistant will provide administrative support to those applying or considering applying for grants and Fellowships. They will also support those who have successfully secured research funding.

You will be educated to at least A Level standard or equivalent or possess a comparable level of practical experience. The successful candidate will be highly organised, computer literate, and have excellent attention to detail. Good communication and people skills are also prerequisites for the role, which involves interacting with a range of stakeholders in the Department, the wider University and externally. For more details, please see the Further Particulars.

The position is offered on a permanent, full-time basis, though we also welcome applications from individuals who wish to be considered for part-time working (minimum 30 hpw) or other flexible working arrangements.

Informal enquiries should be directed to Tracey Flack, pdnhr@pdn.cam.ac.uk.

Apply

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

On the online form, in the suitability for the role section, you should explain the reasons for your application and how your knowledge, skills and experience match the requirements of the role. The full contact details for two professional referees should be provided; one of whom should be your current line manager. Please note that we will assume that you are happy for us to approach your referees at any stage, unless you indicate otherwise in the space provided on the form.

The closing date for applications is midnight on 28 April 2024. Interviews will take place shortly after the closing date.

Please quote reference PM45639 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Project Title: Sex-dependent role of dopamine D3 receptors in the individual vulnerability to develop compulsive drug seeking and taking behaviour: preclinical investigations using a novel highly selective antagonist

Supervisor: Professor David Belin

Department/Institute: Physiology, Development & Neuroscience (PDN)

Industrial Partner: Shionogi

Project details:

The opioid epidemic that has been claiming the lives of over half a million people in the US in the past decade is reaching the UK. There are still no effective treatments for addiction to opiate and other drugs such as cocaine and alcohol, thereby limiting our ability to help those who suffer from this debilitating psychiatric disorder, in part due to our lack of understanding of the cellular mechanisms mediating the transition from controlled to compulsive drug seeking and taking behaviour, the hallmark of substance use disorder. Among candidate mechanisms, those downstream of the dopamine D3 receptor, whose expression is profoundly exacerbated by exposure to addictive drugs, have long stood out. However, the role of this receptor in compulsive drug-seeking behaviour has never been determined due to the lack of appropriate procedures in non-human species. Capitalising on a novel animal model of compulsive heroin-seeking habits developed by the Belin lab, a new multi-million-pound partnership with Shionogi has recently been launched to test, among others, the therapeutic potential, and the associated neural signature, of a new highly selective dopamine D3 receptor on drug-seeking habits, compulsive drug seeking and escalation of drug self-administration in male and female rats. This programme of research at the interface of Behavioural neuroscience, neuropharmacology and molecular biology will provide a unique opportunity for a PhD student to acquire a deep knowledge of the psychological and neural basis of substance use disorders while also acquiring a wide range of experimental skills in a very supportive environment.

The industrial partner is one of the few Big Pharma laboratories left investing in fundamental research in neuroscience and pursuing the development of novel treatments for CNS disorders. It has long been interested in expanding their drug discovery strategy to drug addiction. Shionogi has become a primary industrial partner of the Cambridge landscape and is very active in its collaboration with the Cambridge Neuroscience Community. Over the past five years, Shionogi has supported a new line of research into the role of peripheral mu opiate receptors in the behavioural effects of opiates in the context of a BBSRC-ICase studentship with the Belin that has proven very successful, thereby being a testament to the commitment of Shionogi to support research in the field of substance use disorders.

Applicants will be expected to have extensive experience with chronic intravenous self-administration procedures in rats.

Further information on the Cambridge Bioscience DTP PhD programme can be found at this link: https://bbsrcdtp.lifesci.cam.ac.uk/bbsrc-dtp-programme/icase-studentships. Full details of the University's entrance requirements and scholarships are specified in the following link: https://www.postgraduate.study.cam.ac.uk/.

Funding

Full funding covering Maintenance at the UKRI stipend rate (£20,780 for the academic year 2025/26) and the University Composition Fee at the Home UK rate (2025-26 £10,356) is provided for the studentship, with effect from 1 October 2025.

This studentship is only available to students who qualify for UK home fees. Please check your eligibility: https://www.postgraduate.study.cam.ac.uk/finance/fees/what-my-fee-status.

Fixed-term: The funds for this post are available for 4 years.

Application Process

To apply please visit: https://www.postgraduate.study.cam.ac.uk/courses/directory/blpdpdpdn and click 'Apply Now' selecting the following course:

• PhD in Physiology, Development & Neuroscience (Full-time)
• Start Date: 1st October 2025
• Project Supervisor: Professor David Belin
• Project Title: Include title as listed above
• Research Proposal: Include project details as listed above

Applications should include:

• Two academic references
• Transcript
• CV/resume
• Evidence of competence in English (If required - you can check using our tool)
• Statement of Interest outlining your suitability, why you are interested in a PhD in this area, your background and research interests.
• School of Biological Sciences - Widening Participation Questionnaire (applicants are asked to complete an additional form to provide contextual information about their previous study. Find out more about our use of contextual information here: https://www.postgraduate.study.cam.ac.uk/applying/contextual-data.

For queries related to this PhD studentship, please contact Professor David Belin email bdb26@cam.ac.uk.

Closing date

Completed applications (with ALL supporting documentation and references) to be submitted via the portal by 23:59pm (midnight) UK time on the 22nd of April 2025 at the latest. Interviews will be scheduled for the 1st of May.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Would you like to join a friendly and busy department? The Department of Physiology, Development and Neuroscience (PDN) is looking for a cleaner to join our team providing an efficient and reliable service to our buildings located in central Cambridge.

Our small team of cleaners make essential contributions to our community. You will work as part of the team providing a high standard of cleaning in all areas. Duties will include washing of scientific glassware, cleaning research and teaching laboratories, lecture theatres, offices, corridors, stairways and toilets.

No formal qualifications are required as training will be provided, however NVQ Level 1 Cleaning and Support Services Skills would be advantageous. Experience of laboratory and/or office cleaning would be beneficial. Good communication skills are essential as is the ability to follow written and verbal instructions from supervisors. A willingness to be flexible in approach and reliability are essential.

The position is offered on a permanent, part-time basis, 32 hours per week. The hours of work are flexible, between 7am and 4pm

The University is an accredited Real Living Wage (RLW) employer, and will ensure that employees are paid at least the prevailing RLW rate.

For more information about this post, please contact Katie Conran, Facilities and Operations Manager kc662@cam.ac.uk.

Apply:

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

On the online form, in the suitability for the role section, you should explain the reasons for your application and how your knowledge, skills and experience match the requirements of the role. The full contact details for two professional referees should be provided; please note that we will assume that you are happy for us to approach your referees at any stage, unless you indicate otherwise in the space provided on the form.

If you are unable to use the online system for your application, please contact Tracey Flack, pdnhr@pdn.cam.ac.uk.

The closing date for applications is midnight on 13 April 2025. Interviews will be held on 24 April 2025.

Please quote reference PM45497 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The Department of Physiology, Development & Neuroscience particularly welcomes applications from candidates from a BME background for this vacancy as they are currently under-represented in our department.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Applications are invited for a trainee laboratory technician to support the research work in the Loke Centre for Trophoblast Research (Loke CTR), starting in late July 2025. This is an exciting opportunity for somebody passionate about getting started in scientific research to join a vibrant and friendly team of researchers in the heart of Cambridge and work in a state-of-the-art laboratory.

About the role

The role will support the research activities of the groups operating in the Loke CTR shared laboratory space based in the department of Physiology, Development and Neuroscience (PDN). There are 6 research groups based permanently in the shared lab space, led by Prof Kathy Niakan, Prof Bill Colledge, Prof Erica Watson, Dr Thorsten Boroviak, Dr Courtney Hanna, and Dr Claire Senner. The role will provide direct support for approximately researchers across these groups, including the Loke CTR Next Generation Fellows.

This is an exciting role with varied responsibilities. You will support our tissue culture facilities, a molecular biology lab, histology preparation room, and placental, endometrial and human embryo shared facility. You will provide laboratory housekeeping to ensure a well-functioning laboratory environment, including performing tissue culture and histology techniques, preparing stock solutions, monitoring and replenishing stocks, and contributing to the health and safety culture of the research groups. You will also provide support for the Biology of the Human Uterus in Pregnancy and Disease Tissue Bank, which is used by Loke CTR researchers across the University with an interest in pregnancy and early development.

The Loke Centre for Trophoblast Research (Loke CTR)

The Loke Centre for Trophoblast Research (Loke CTR) is a centre of excellence to promote scientific study of the placenta, early development and maternal-fetal interactions during pregnancy. The Loke CTR unites 28 group leaders across 10 departments and affiliated institutes and provides diverse opportunities for scientific interaction through events, training and shared state-of-the-art facilities to support world leading trophoblast-related research across Cambridge.

What you will need You should be educated to a minimum of A-level or NVQ level 3 in a biological or other related subject and/or relevant laboratory experience in molecular biology. You should have a good understanding of molecular biology and previous research experience would be an advantage.

Good communication skills and the ability to work effectively within a team are essential. You should have meticulous documentation and note-keeping skills and be able to manage your time and work effectively.

The position is flexible to suit individual needs. We will make an appointment for 1 year in the first instances and welcome applications from candidates interested in full-time work or part-time work for a minimum of 3 days per week. Due to the nature of the work, you will be required to work on site.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

The closing date for applications is 21st April 2025.

To find out more about the Loke CTR please visit our website at: https://www.trophoblast.cam.ac.uk/

For an informal conversation about the role, please contact Erin Slatery, Loke CTR Executive Manager (execmgr.lokectr@pdn.cam.ac.uk). If you have any queries about the recruitment process, please contact Tracey Flack, Chief HR Administrator (pdnhr@pdn.cam.ac.uk).

Please quote reference PM45421 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

An exciting opportunity has arisen for a versatile custodian to join our friendly team in the Department of Physiology, Development and Neuroscience, providing an efficient, safe, reliable and welcoming service in our buildings located in central Cambridge.

The role holder will provide day to day support in the Department, supporting Reception, dealing with visitors and contractors, assisting with events, portering and supporting the facilities team with minor maintenance across our two buildings which consist of laboratories, classrooms, offices and lecture theatres.

The successful candidate will have good organisational and time management skills, as well as basic DIY and IT skills. You will have a flexible working approach and have good interpersonal, team-working and customer service skills. You will be willing to learn and whilst experience in a caretaking or similar role would be advantageous, it is not essential as training will be given.

For more information about this post, please contact Katie Conran, Facilities and Operations Manager kc662@cam.ac.uk.

This post is offered on a full-time basis, working 36.5 hours per week, Monday-Friday.

Fixed-term: The funds for this post are available for 12 months in the first instance.

Apply:

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

On the online form, in the suitability for the role section, you should explain the reasons for your application and how your knowledge, skills and experience match the requirements of the role. The full contact details for two professional referees should be provided, one of who should be your most recent line manager. Please note that we will assume that you are happy for us to approach your referees at any stage, unless you indicate otherwise in the space provided on the form.

The closing date for applications is 23 March 2025. Interviews will be held on Tuesday 1 April.

If you are unable to use the online system for your application, please contact Tracey Flack, pdnhr@pdn.cam.ac.uk.

Please quote reference PM45242 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Applications are invited for an enthusiastic and motivated Postdoctoral Research scientist to work on a Medical Research Council (MRC) funded project with Dr Erica Watson and Prof William Colledge.

The Watson lab is a developmental biology group based in the Department of Physiology, Development and Neuroscience at the University of Cambridge (https://www.pdn.cam.ac.uk/directory/watson-erica) and is a member of the Loke Centre for Trophoblast Research (https://www.trophoblast.cam.ac.uk). The over-arching goal of this lab is to explore the epigenetic mechanisms behind transgenerational inheritance of developmental and metabolic phenotypes in a genetic mouse model of abnormal folate metabolism. Key research avenues aim to uncover important epigenetic changes in the germ cells that result from abnormal folate metabolism and how these changes influence epigenetic stability, gene transcription, and fetoplacental development in the multiple generations that follow. The Watson lab is an inclusive and welcoming group, committed to mentoring and supporting career development of all members.

The Colledge lab is also based in the Department of Physiology, Development and Neuroscience. Professor Colledge is a reproductive physiologist who is interested in all aspects of mammalian fertility and has considerable experience of using transgenic mice as experimental models.

We are looking for a postdoctoral scientist to investigate sperm non-coding RNA (ncRNA) as a possible mediator of transgenerational inheritance of congenital malformations caused by abnormal folate metabolism. You will be the key person to manage the programme, run the experiments, analyse the data, and write manuscripts for publication.

The successful candidate should have completed (or will be about to complete) their PhD in a relevant field. They should have a background in molecular techniques and mouse embryo dissection, genotyping and phenotyping. They will have excellent organisational skills and a demonstrable aptitude for research. Experience in conducting zygote microinjections, embryo transfer, MeDIP-seq or RNA-seq (and/or other high-throughput technologies), and/or basic bioinformatic analysis is desirable but not essential. Animal husbandry experience and Home Office Training would be an advantage.

Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will be appointed at Research Assistant level, which will be amended to Research Associate once the PhD has been awarded.

Salary Ranges: Research Assistant: £32,296-£34,866, Research Associate: £36,924- £45,163

Fixed term: The funds for this post are available for 30 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a security check.

Apply

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

To apply for this post, please upload your CV and a letter detailing why you want to be a part of this project and how this post will be a good stepping-stone for your career. We also need the names and contact details for two people, who can provide a professional reference.

The deadline for applications is 31 March 2025 and we aim to hold in-person or Zoom interviews for the shortlisted candidates shortly after the closing date.

Informal enquiries can be made to Prof William Colledge, whc23@cam.ac.uk.

Please quote reference PM45144 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The Department of Physiology, Development and Neuroscience particularly encourages candidates from a BME background to apply for this vacancy.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

The Microscopy Bioscience Platform in the School of Biological Sciences is recruiting for an enthusiastic microscopy technician to join the Electron Microscopy team. The facility provides advanced imaging services, currently serving over 100 research groups in the University as well as external, commercial users. At present the centre has an FEI Verios 460 SEM and Tecnai G2 TEM with associated sample preparation equipment. This role will provide essential support to improve research throughput of our state-of the-art EM facility. The role holder will be responsible for assisting the Electron Microscopy Specialist and Lead Electron Microscopist in the delivery of a professional and comprehensive EM service. This will include all aspects of project design, from initial discussion of methodology, to sample preparation, imaging and data interpretation.

The role holder will work closely with the senior members of the team in order to achieve the platform's aims of providing access to advanced imaging capabilities in a sustainable environment through efficient cost recovery. This role requires a real enthusiasm for electron microscopy and would be ideal for someone who wishes to develop their microscopy skills with the guidance of our expert EM staff.

You should have practical experience of biological scientific research work, a high degree of precision in following protocols and excellent communication skills. Please refer to the further particulars document for a full list of the essential knowledge, skills and experience required for the role.

Informal enquiries are welcomed and should be addressed to Filomena Gallo, fg337@cam.ac.uk.

Limited funding: The funds for this post are available for 4 years in the first instance.

Apply

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

On the online form, in the suitability for the role section, you should explain the reasons for your application and how your knowledge, skills and experience match the requirements of the role. The full contact details for two professional referees should be provided, one of whom should be your current line manager. Please note that we will assume that you are happy for us to approach your referees at any stage, unless you indicate otherwise in the space provided on the form.

The closing date for applications is midnight on 14 March 2025. Interviews will take place w/c 6th April 2025.

Please quote reference PM45033 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

An exciting opportunity has arisen for a Departmental Administrator to join the Department of Physiology, Development & Neuroscience. The Department is a large, complex and welcoming Department with an exceptional record in teaching and research. This senior post is integral to the Department, with overall responsibility for the professional services team in all operational areas. The successful candidate will advise the joint Heads of Department and other senior academic staff on strategy, planning and policy issues. The role also involves the opportunity to contribute to School-wide projects and close collaboration with the other Departments in the School of Biological Sciences.

We are looking for an experienced administrator who has experience of managing people and budgets, as well as the ability to operate at a strategic level. The successful candidate will have excellent interpersonal and communication skills and the ability to build effective relationships at all levels.

The role holder will be educated to degree level (or have equivalent experience). They will have experience in management and administration in a complex organisation and the ability to lead teams and problem solve. Please refer to the further particulars document for a full list of the essential knowledge, skills and experience required for the role.

Informal enquiries are encouraged and should be addressed to Professor Bill Colledge (Joint HoD), pdnhod@pdn.cam.ac.uk or Olivia Speed (current DA), pdnadmin@pdn.cam.ac.uk.

Apply

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role.

The full contact details for two professional referees should be provided, one of whom should be your current line manager. Please note that we will assume that you are happy for us to approach your referees at any stage, unless you indicate otherwise in the space provided on the form.

The closing date for this post is Monday 3 March 2025, interviews will be held on 4 April.

Please quote reference PM44802 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Applications are invited for two Research Assistant positions in Dr. Keshavarzi's lab at the University of Cambridge, Department of Physiology, Development and Neuroscience. The lab's research, funded by the Wellcome Trust, focuses on the organisation and function of neural circuits underlying the sense of direction and self-motion, using mice. For more details, please visit the lab website https://www.keshavarzilab.com/. Projects

The two positions focus on distinct aspects of the lab's research, with opportunities for collaboration for candidates with overlapping skills and interests:

1. Neural Circuit Organisation in the Head Direction System: This project investigates the organisation of neural circuits in the head direction system, focusing on the retrosplenial cortex and its connections with cortical and thalamic areas. Techniques include patch-clamp recordings in brain slices, optogenetics, and neural tracing. Candidates may also participate in in vivo methods and behavioural experiments to connect circuit structure and function, particularly if pursuing a PhD in the lab.

2. Development and Testing of Behavioural Analysis Software: This project focuses on testing an open-source software, movement (https://movement.neuroinformatics.dev/index.html in collaboration with neuroinformaticians), for analysing animal behaviour. Responsibilities include evaluating movement and related tools and contributing to its publication. Strong programming skills (ideally Python) are required. Additional responsibilities involve maintaining the lab's behavioural acquisition software (Bonsai-based), with collaborator support. The role also offers opportunities to gain experimental skills, including behavioural training, surgical procedures, and in vivo electrophysiology (Neuropixels), ideal for transitioning into a research project and pursuing a PhD in the lab.

Both positions are suited for candidates seeking long-term commitment, with potential for extension and PhD application with the lab. Exceptional candidates may receive lab-funded PhD support.

Key Experience and Competencies

We are seeking two self-motivated individuals with experience in cellular neurophysiology or circuit/systems neuroscience research.

Essential Qualifications:

• Experienced in either Slice patch-clamp recording and data analysis (Position 1), or programming (Python, MATLAB) for data acquisition and analysis (Position 2).
• Undergraduate or master's degree in Neuroscience or a related field with evidence of academic excellence.
• Strong communication skills in English.

Desirable Skills:

• Experience with optogenetics, stereotactic surgery, quantitative animal behaviour, neural recording techniques.
• Expertise in building custom experimental setups.

Research Environment

Our lab fosters a welcoming, inclusive, and supportive research environment. We are committed to the career development of lab members and provide mentorship throughout their journey. The research assistants will join a vibrant multidisciplinary research environment, with regular interactions with other neuroscience groups in the department. Regular departmental seminars and events hosted by the Cambridge Neuroscience Network offer excellent opportunities for networking and scientific discussion.

How to Apply

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please submit the following documents:

• A CV, including overall grades for each degree.
• A cover letter addressing: Your motivation for joining the lab. How your skills align with the job description. Your research ambitions and career goals.
• Contact details for two referees.

For informal inquiries, contact Dr. Keshavarzi at sk2244@cam.ac.uk.

Closing Date: 21 February 2025. Applications will be reviewed on a rolling basis, and the position may close early once filled.

Start Date: Available from March 2025 for one year in the first instance.

Please quote reference PM44821 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The Department particularly welcomes applications from candidates from Black, Asian, or Minority Ethnic backgrounds.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

The Cardona Lab are pleased to invite applications for the position of Research Associate in the Experimental and Comparative Connectomics Laboratory. The primary purpose of the role is to support the research of Dr Albert Cardona, whose lab is interested in the neural circuit basis of behaviour. For details of recent projects in the lab, see https://tinyurl.com/cardonalabpubs . For a description of the lab's focus see https://www.pdn.cam.ac.uk/directory/albert-cardona.

The post holder will have a neuroscience background, with a Ph.D. in Neurobiology or related discipline, with extensive experience with patch-clamp recording of Drosophila larval neurons, ideally in mushroom body output neurons and dopaminergic neurons. The ideal candidate will also have ample experience with optogenetics and functional connectivity mapping in Drosophila, including experience with Drosophila genetics and its driver lines approach to monitoring and manipulating neuronal activity in individual neurons, as well as excellent data analysis skills, and experience with learning and memory paradigms in Drosophila.

Fixed Term: the funds for this post are available until 31 December 2025.

Informal enquiries about the position can be made to Dr Albert Cardona (ac2040@cam.ac.uk).

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

To apply for this post, please submit a CV and a covering letter detailing why you want to be part of this project and how this post will be a good stepping-stone for your career. We also need the contact details for two people who can provide a professional reference.

The closing date for applications is 5th February.

Please quote reference PM44798 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The Department of Physiology, Development & Neuroscience particularly encourages women and candidates from a Black, Asian or Minority Ethnic background to apply for this vacancy.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.