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Current jobs in the Department of Pharmacology at the University of Cambridge.
Updated: 1 min 21 sec ago

Facilities and Safety Manager

Fri, 17/03/2023 - 00:00

The Department of Pharmacology, University of Cambridge, is a thriving, friendly and dynamic community of staff and students, dedicated to the pursuit of world-class research, teaching and learning, and driven by curiosity, quality, collaboration and innovation. We offer a welcoming work environment where you can feel valued, encouraged to develop, and supported to achieve your full potential.

We are looking to recruit a Facilities and Safety Manager to join our friendly and dynamic operations team. The Facilities and Safety Manager is responsible for the day-to-day operation of highly serviced research facilities, and the management of a skilled support staff team enabling research and teaching activities in the Department. This includes the smooth operation of general building services, in conjunction with the Estates Division, the provision of specialised research infrastructure in combination with external contractors, and the management of Health and Safety by supporting and advising the Head of Department (HoD).

The technical support team covers a range of grades and specialist work areas, from cleaning and general building maintenance, to teaching laboratories and specialist imaging facilities. The Facilities and Safety Manager leads this team by setting the culture, managing workloads, coordinating activities, recruiting, reviewing and developing staff.

Cambridge is a world-leading University and this is an exciting opportunity for an enthusiastic and motivated individual to join our team. Alongside a competitive salary and 36 days of annual leave per annum, University staff are eligible for a comprehensive package of benefits and services including discounts on shopping, health care, financial services, and public transport.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check.

Applications are welcome from internal candidates who would like to apply for the role on the basis of a secondment from their current role in the University.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

If you have any questions about this vacancy or the application process, please contact the HR Team (HR@phar.cam.ac.uk).

Please quote reference PL35971 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs

Postdoctoral Researcher: Innovating Protein Interactions for Biology and Medicine (Fixed Term)

Tue, 14/03/2023 - 00:00

A talented and creative postdoc researcher is sought to work in Mark Howarth's group (https://www.phar.cam.ac.uk/research/Howarth/research) on an EPSRC-funded project. The project relates to the development of novel protein interactions for medical biotechnology and controlling cell behaviour. SpyTag is a genetically-encoded peptide created by the Howarth lab, which forms an irreversible covalent bond to its protein partner SpyCatcher. SpyTag provides a unique resource for molecular assembly and has been applied by hundreds of groups around the world for many areas of basic research and biotech. SpyTag has entered clinical trials for vaccines and is in development for CAR-T cell therapy of cancer.

This project will apply rational design and library-based selections to create new SpyTag-based technologies, enabling a novel toolbox of protein architectures for synthetic biology and control of cell behaviour. There will then be the opportunity to apply these new generation architectures towards one project of special interest to the appointee. The Howarth group currently works on areas including vaccines for global health (SARS-CoV-2, influenza and emerging viruses), immunology, force-dependent cell signalling (mechanobiology), and therapeutic targeting in the blood and GI tract (through antibodies/gastrobodies). According to the interest of the applicant, it may also be possible to apply X-ray crystallography or cryoEM for insight into the new resources. We will provide training in unfamiliar methods.

Responsibilities will include managing research activities, generating high quality data and developing scientific techniques. You will be expected to contribute intellectually to the direction of the research project. It is expected that you will present your data locally at lab meetings and seminars, and more widely at international scientific conferences. You will be expected to assist in drafting scientific manuscripts and may contribute to day-to-day supervision of Masters or PhD students.

You will hold a PhD, or be near completion of a PhD, in Biochemistry, Cell Biology, Chemical Biology or a related area. You will be skilled at presenting your data, verbally and in writing. You should be committed to collaborative and interdisciplinary research and be able to work both independently and as part of a team. Experience with recombinant protein expression and biophysical analysis is essential. Experience in cell biology methods (e.g. flow cytometry, immunoblotting, microscopy) or library-based screening will be advantageous.

Applications are particularly welcome from women, black and minority ethnic candidates.

The salary range if appointed as a Research Associate is Grade 7 £34,308 - £42,155 per annum, and the salary range if appointed as Research Assistant is Grade 5 £27,929 - £32,348 annum with promotion to Research Associate on attainment of PhD.

Fixed-term: The funds for this post are available for 2 years in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries are welcomed and should be directed to Prof Mark Howarth mh2186@cam.ac.uk.

If you have any questions about the application process please contact the HR team at hr@phar.cam.ac.uk.

Please quote reference PL35857 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs

Research Associate/Assistant (Fixed Term)

Fri, 10/03/2023 - 00:00

Applications are invited for a full-time post-doctoral position to select aptamers against specific bacterial outer membrane targets. The Mela laboratory has previously shown that DNA nanostructures can be functionalised with aptamers to create bacteria-specific drug-delivery vehicles that can potentiate their antimicrobial cargo. The successful candidate will build on this approach. The project will initially focus on the development of microfluidics-based SELEX for the identification of aptamers that bind to specific proteins on the outer membrane of bacteria. Once aptamers have been selected, their application will be two-fold. First, the aptamers will be combined with DNA nanostructures to create drug delivery vehicles in which the aptamers anchor antimicrobial-carrying nanostructures to specific proteins on the bacterial surface. Second, the potential of the aptamers themselves to have pharmacologically-relevant effects through binding and blocking their target proteins will be explored.

The post is associated with a Royal Society University Research Fellowship awarded to Dr Ioanna Mela, the aim of which is to explore DNA nanostructures as drug delivery vehicles. The position will be based primarily in the Department of Pharmacology at the University of Cambridge, but there will be opportunities to work with and in collaborating labs at the MRC-LMB (Dr Emmanuel Derivery), Department of Chemical Engineering and Biotechnology, University of Cambridge (Professor Clemens Kaminski) and Kyoto University (Professor Hiroshi Sugiyama). The work will also involve some DNA cloning, atomic force microscopy and fluorescence microscopy.

Applicants should have a first degree or PhD in an area relevant to the project. The key duties and responsibilities will include, but are not limited to: developing research objectives and conducting the research project, continually updating knowledge and understanding in the field, translating knowledge and advances to the research activity; supporting research activities and communication through participation at group meetings/seminars; contributing to the supervision of junior researchers and PhD students and acting as a mentor to less experienced colleagues; writing up research work for publication; dissemination of research results by presentation at national and international conferences. The successful candidate will have experience in DNA nanotechnology and/or aptamer selection, molecular biology and microbiology, and fluorescence microscopy. Some experience with DNA cloning and recombinant protein expression and purification is desirable but not essential. Experience working with microfluidics would be an asset.

The funds for this post are available for 42 months. The salary range if appointed as a Research Associate is £32,348 - £42,155 per annum and the salary range if appointed as Research Assistant is £27,929 - £32,348 per annum with promotion to Research Associate on attainment of PhD if applicable.

Informal enquiries about the position can be made to Dr Ioanna Mela (im337@cam.ac.uk).

The Department of Pharmacology holds an Athena SWAN bronze award, demonstrating a commitment to provide equal opportunities and to advance the representation of women in science subjects. We welcome applications from all qualified candidates irrespective of gender but, as women are currently under-represented at this level in our department, we strongly encourage applications from female candidates. Appointment will be based on merit alone.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

If you have any questions about this vacancy or the application process, please contact the HR Team (HR@phar.cam.ac.uk).

Please quote reference PL35773 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs

Research Assistant in cell biology of ageing (Part Time, Fixed Term)

Wed, 01/03/2023 - 00:00

We are seeking a part-time (0.5 FTE) Research Assistant to join the laboratory of Dr Delphine Larrieu (www.larrieulab.com) to contribute to our team's efforts to decipher the cellular mechanisms behind nuclear envelope dysfunction in normal ageing and in premature ageing syndromes (progeria).

This is a great opportunity to join a young, diverse and dynamic team in the Department of Pharmacology, central Cambridge.

The successful candidate will have a track record of effectively working as part of a team as their work will be contributing to several ongoing projects in the lab. Core duties will involve routine tissue culture, cloning and other molecular work, western blotting, immunofluorescence as well as biochemistry. Other responsibilities will include preparation of reagents, maintenance of lab stocks and assist in the day-to-day running of the laboratory.

The successful candidate will have: Degree or equivalent in life sciences; previous research laboratory experience; mammalian tissue culture - significant experience required; previous significant experience in molecular biology techniques: cloning, western blotting, protein analysis or immunofluorescence; fluorescence microscopy experience preferred; high attention to detail and good record keeping; good communication and organisational skills; reliability, efficiency, curiosity and enthusiasm.

Starting date: 1st April 2023. Please note that applicants may be invited for interview prior to the closing date.

Limited funding: The funds for this post are only available for one year from April.

The Department holds an Athena SWAN bronze award and is committed to provide equal opportunities and advance the representation of women in science. We welcome applications from all candidates irrespective of gender. Appointment will be based on merit alone.

Fixed-term: The funds for this post are available for 12 months in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please ensure that you upload your Curriculum Vitae (CV) and a brief statement outlining your research interests in the Upload section of the online application. Informal inquiries can be made by contacting Dr Delphine Larrieu (dl437@cam.ac.uk)

If you have any questions about the application process please contact the HR team at hr@phar.cam.ac.uk.

Please quote reference PL35674 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs

Research Assistant in G protein-coupled receptor pharmacology (Fixed Term)

Wed, 22/02/2023 - 00:00

Applications are invited for a Research Assistant position in the University of Cambridge, Department of Pharmacology, central Cambridge, working in the laboratory of Prof Graham Ladds.

The lab uses multidisciplinary approaches to investigate G protein-couped receptor (GPCR) signalling and enjoys collaborations with both academia and industry. This project has arisen through a direct collaboration with Takeda Pharmaceuticals. You can find more information about the lab and current projects at: https://www.phar.cam.ac.uk/research/Ladds and on twitter: @GPCR_Ladds.

The successful candidates should have a BSc in Pharmacology, Biochemistry, Medicine, or a related field. The project focusses upon GPCR pharmacology so knowledge of in the used of GPCR research would be an advantage. The appointee will be enthusiastic, methodical, work effectively as part of a team, be able to perform and analyse experiments with appropriate supervision of a Post-doctoral research associate, willing to engage with the research literature, and be able to write regular research reports. Experience of using GraphPad Prism is desired.

Funds are available for a fixed term of 12 months, after probationary review and is available immediately. The salary range for Research Assistant is £27,929-£32,348.

Key duties will be to assist our Post-doctoral research associate team studying how regulatory proteins receptor activity modifying proteins (RAMPs) contribute to the gastric inhibitory polypeptide (GIP) receptor pharmacology. We will be studying GIPR agonist bias and cellular trafficking. We are keen to explore new signalling pathways modulate by GIPR and to determine how RAMPs influence these responses. Training in these techniques will be provided. This work builds upon ongoing projects in the Ladds-GPCR lab. More details are available on request.

Interviews will take place in mid-March.

The expected starting date is April 2023, although there is some flexibility to start slightly earlier or later.

Fixed-term: The funds for this post are available for 12 months in the first instance.

The Department holds an Athena SWAN bronze award and is committed to provide equal opportunities and advance the representation of women in science. We welcome applications from all candidates irrespective of gender. Appointment will be based on merit alone.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

For the online application you will need to provide your personal details, names and e-mail addresses of two referees familiar with your academic performance, CV, your availability and a cover letter (including a description of your experience as it relates to the job specifications).

Informal inquiries can be made by contacting Prof Graham Ladds (grl30@cam.ac.uk).

If you have any questions about the application process please contact the HR team at hr@phar.cam.ac.uk.

Please quote reference PL35590 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs

Research Assistant/Associate in G protein-coupled receptor pharmacology (Fixed Term)

Wed, 22/02/2023 - 00:00

Applications are invited for a Postdoctoral Research Associate position in the University of Cambridge, Department of Pharmacology, central Cambridge, working in the laboratory of Prof Graham Ladds.

The lab uses multidisciplinary approaches to investigate G protein-couped receptor (GPCR) signalling and enjoys collaborations with both academia and industry. This project has arisen through a direct collaboration with Takeda Pharmaceuticals. You can find more information about the lab and current projects at: https://www.phar.cam.ac.uk/research/Ladds and on twitter: @GPCR_Ladds.

The successful candidates should have (or be close to completing) a PhD in Pharmacology, Biochemistry, Medicine, or a related field. The project focusses upon GPCR pharmacology so experience in the used of mammalian tissue culture and BRET-based assays for GPCR research would be an advantage. The appointee will be enthusiastic, methodical, work effectively as part of a team, be able to perform and analyse experiments with appropriate supervision, willing to engage with the research literature, and able to write regular research reports. Experience of using GraphPad Prism is desired but not essential.

Funds are available for a fixed term of 12 months, after probationary review and is available immediately. Successful candidates who have not been awarded their PhD by the appointment date will be appointed as a Research Assistant at Grade 5 (£27,929 - £32,348). Upon the award of the PhD the individual will be promoted to Research Associate, Grade 7 (£34,308 - £42,155).

Key duties will be to design, perform and analyse how the key regulatory proteins receptor activity modifying proteins (RAMPs) contribute to the gastric inhibitory polypeptide (GIP) receptor pharmacology. We will be studying GIPR agonist bias and cellular trafficking. We are keen to explore new signalling pathways modulate by GIPR and to determine how RAMPs influence these responses. Training in these techniques will be provided. This work builds upon ongoing projects in the Ladds-GPCR lab. More details are available on request.

Interviews will take place in mid-March.

The expected starting date is April 2023, although there is some flexibility to start slightly earlier or later.

Fixed-term: The funds for this post are available for 12 months in the first instance.

The Department holds an Athena SWAN bronze award and is committed to provide equal opportunities and advance the representation of women in science. We welcome applications from all candidates irrespective of gender. Appointment will be based on merit alone.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

For the online application you will need to provide your personal details, names and e-mail addresses of two referees familiar with your academic performance, CV, your availability and a cover letter (including a description of your experience as it relates to the job specifications).

Informal inquiries can be made by contacting Prof Graham Ladds (grl30@cam.ac.uk).

If you have any questions about the application process please contact the HR team at hr@phar.cam.ac.uk.

Please quote reference PL35591 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs

Assistant Teaching Professor (Fixed Term)

Tue, 21/02/2023 - 00:00

Applications are invited for a 5-year fixed-term University Assistant Teaching Professor in the Department of Pharmacology, University of Cambridge with effect from 1 July 2023 , or as soon as possible thereafter. The Department offers excellent facilities for teaching 2nd and 3rd year students on several different courses, as well as supporting research in a broad range of fields, including: cell signalling, cancer, pain, neuropharmacology, and vascular pharmacology.

The role holder will be based in Central Cambridge. The primary responsibility will be to provide teaching and administrative cover for University Teaching Officers during periods of academic and other types of leave. The key duties of the role will include but not be limited to: giving lectures and seminars, running practical classes, and supervising undergraduate project and dissertation students, as well as taking an active part in undergraduate examinations and administrative duties within the Department of Pharmacology. A full description of the teaching and research activities in the Department can be found at http://www.phar.cam.ac.uk.

The successful applicant will have a PhD in a relevant specialist subject area and a track record in teaching at a higher education institution.

Appointments will be made at University Assistant Professor level. The starting salary, depending upon experience, will be in the region of £43,414-£54,949 pa. Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure, a security check and a health assessment. Whether the outcome is satisfactory will be determined by the University.

Applications from agencies will not be considered.

The Department holds an Athena SWAN bronze award, demonstrating a commitment to provide equal opportunities and to advance the representation of women in science subjects. We particularly encourage applications from women and from other underrepresented groups. Appointment will be based on merit alone.

Fixed-term: The funds for this post are available for 5 years in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please ensure that in the Upload section of the online application you upload your Curriculum Vitae (CV) and a covering letter (maximum 2 pages outlining your professional, teaching and research experience and how you will contribute to our teaching). If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

If you have any questions about this vacancy or the application process, please contact the Head of Department, Prof Laura Itzhaki (lsi10@cam.ac.uk).

Please quote reference PL35578 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs

Research Assistant/Associate (Fixed Term)

Thu, 12/01/2023 - 00:00

Applications are invited for a researcher position in the laboratory of Dr Catherine Lindon at the Department of Pharmacology, University of Cambridge. We are seeking a motivated cell biologist to undertake studies of the mode of action of novel tools for Targeted Protein Degradation (TPD). Small molecule PROTACs harnessing the cellular ubiquitination machinery to destroy targets of clinical importance are at the forefront of a revolution in therapeutic strategies, yet there are still many parameters of the relevant ubiquitination pathways that are not well understood.

This study is a great opportunity to gain experience in a novel and rapidly expanding field and to contribute to important and timely research questions about how PROTACs find and ubiquitinate their targets, and what cellular factors modify the success of TPD strategies. This knowledge will feed into therapeutic strategies of the future. More information about the laboratory is available at: https://www.phar.cam.ac.uk/research/lindon.

The successful applicant should be about to obtain a PhD or have already obtained a PhD, ideally within the last 5 years. Experience in molecular cell biology is required, and experience in ubiquitin research would be preferred. You must be a careful and methodical worker, be able to take responsibility for your work, interact as part of a tightly knit team and be willing to work in a collaborative environment. You should be self-motivated and able to organise, perform and analyse experiments with minimal instruction. The role holder will be required to relocate to the Cambridge area (if not already resident there).

Key duties/responsibilities will include: developing research objectives, conducting the research project, writing up research for presentation and publication, continually updating knowledge and understanding in the research field, translating knowledge of advances in the subject area into research activity, managing own research/administrative activities and contributing to supervision of junior researchers in the lab.

The funds to begin in this post are available from approximately 1st May 2023 with flexibility in start date.

Successful candidates who have not yet been awarded their PhD by the appointment date will be appointed as a Research Assistant at Grade 5 (£27,929 - £32,348). Upon the award of the PhD the individual will be promoted to Research Associate, Grade 7 (£34,308 - £42,155).

Fixed-term: Funds for this post are available for 36-months.

The Department holds an Athena SWAN bronze award, demonstrating a commitment to provide equal opportunities and to advance the representation of women in science subjects. We welcome applications from all qualified candidates irrespective of gender but, as women are currently under-represented at this level in our department, we strongly encourage applications from female candidates. Appointment will be based on merit alone.

Applications will be assessed as and when they are submitted. Interviews will take place in late February.

The online application is to include your personal details, names and addresses of referees, as well as your CV, research publications list and cover letter.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries about the position can be made to Dr Catherine Lindon (acl34@cam.ac.uk)

For enquiries about the online application process, please contact the HR team by emailing hr@phar.cam.ac.uk.

Please quote reference PL34963 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs

Postdoctoral Research Associate (Fixed Term)

Tue, 10/01/2023 - 00:00

Applications are invited for a Postdoctoral Research Associate position in the Marti-Solano group at the Department of Pharmacology, University of Cambridge (https://www.phar.cam.ac.uk/research/marti/research).

Our group leverages a range of state-of-the-art computational biology techniques to study G protein coupled receptors (GPCRs), an extensive family of proteins found across human cells and tissues. Individual family members detect different signals reaching the cell membrane and convey their messages to signalling partners that activate a variety of physiological responses inside our cells. Due to their capacity to regulate cell responses, GPCRs have become the most common drug targets. However, there are still many aspects of GPCR function that remain unresolved, thus hampering our understanding of the key molecular mechanisms that underlie receptor signalling in cell physiology and in therapeutic responses.

We are looking for a PDRA who can help us address some of these fundamental questions by analysing how differences in GPCR pathway composition can diversify receptor signalling responses across biological systems. This analysis can heavily impact the way in which we study GPCR physiology and drug action, as well as help explain the complex clinical responses of currently available GPCR drugs. The ideal candidate will have a PhD or equivalent qualification obtained in the last 3 years in bioinformatics or computational biology, with strong skills processing, analysing, visualising, and critically interpreting biological data. They should be proficient in at least one scripting language (R or Python) and have working experience with network biology reconstruction and analysis tools like Cytoscape and iGraph. They should be familiar with databases including the Gene Expression Atlas, the Human Protein Atlas, STRING, Reactome, or ChEMBL and have some background knowledge in multi-omics data analysis, cell signalling and / or molecular biology.

The successful candidate will be highly motivated, have excellent time management, organisational and communication skills, and have experience publishing their work. They should be able to work well as part of a team and in a multidisciplinary research environment. The role holder will be required to relocate to the Cambridge area and key responsibilities will include: establishing research objectives together with the principal investigator, leading their research project on a day-to-day basis, presenting their research in internal meetings and international conferences, taking an active part in manuscript writing, and translating new knowledge in the subject area into research activity. They will have the opportunity to supervise more junior group members and will be encouraged to contribute to teaching and dissemination activities.

Online interviews will take place in mid-February.

The expected starting date is May 2023, although there is some flexibility to start slightly earlier or later.

The Department holds an Athena SWAN bronze award and is committed to provide equal opportunities and advance the representation of women in science. We welcome applications from all candidates irrespective of gender. Appointment will be based on merit alone.

Fixed-term: The funds for this post are available for 36 months in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

The application should include personal details, contacts for two referees, your CV, research publications list and cover letter. Informal enquiries about the position can be made to Dr Maria Marti-Solano (mm2402@cam.ac.uk).

For enquiries about the online application process please contact the HR Team, hr@phar.cam.ac.uk

Please quote reference PL34931 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs

Research Assistant/Associate (Fixed Term)

Tue, 20/12/2022 - 00:00

Applications are invited for a Research Associate position in the laboratory of Prof. Ewan St. John Smith at the Department of Pharmacology, University of Cambridge for an immediate start to work on a Wellcome Trust Discovery Award project in collaboration with Dr David Hughes at the University of Glasgow.

The project, ENDASCOP: Establishing Neuronal Drivers And the Spinal Circuitry of Osteoarthritis Pain, will use a combination of viral and transgenic animal technologies to elucidate the roles of sensory neuron subpopulations in a mouse model of osteoarthritis. Numerous techniques will be employed, including: surgery, behavioural analysis, retrograde tracing, neuronal culture, electrophysiology, and immunohistochemistry.

We are looking for a diligent, motivated, and innovative scientist to join our group (www.phar.cam.ac.uk/research/Smith). The role holder will be based in central Cambridge. The key duties and responsibilities will include, but are not limited to: developing and conducting the project, writing up research work for publication, managing own research and administrative activities, helping in the supervision of students and assisting in grant writing.

Successful candidates will likely have demonstrable experience in animal behaviour and/or surgery, and cellular electrophysiology; a valid Home Office Personal Licence is highly desirable, but not essential. You must be a careful and methodical worker, paying attention to accuracy and ready to take responsibility as part of a team. You should be self-motivated and able to organise, perform and analyse experiments with minimal instruction.

Applicants should have, or expect to obtain shortly, a PhD in neuroscience or related discipline. Successful candidates who have not been awarded their PhD by the appointment date will be appointed as a Research Assistant at Grade 5 (£27,929 - £32,348). Upon the award of the PhD the individual will be promoted to Research Associate, Grade 7 (£34,308 - £42,155).

The funds for this post are available initially for 36-months, but subject to extension to up to 96 months, should both parties agree.

The Department holds an Athena SWAN bronze award, demonstrating a commitment to provide equal opportunities and to advance the representation of women in science subjects. We welcome applications from all qualified candidates irrespective of gender but, as women are currently under-represented at this level in our department, we strongly encourage applications from female candidates. Appointment will be based on merit alone.

Applications will be assessed as and when they are submitted and it is anticipated that initial interviews will take place in February.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries about the position can be made to Prof. Ewan St. John Smith (es336@cam.ac.uk).

The online application is to include your personal details, names and addresses of referees, as well as your CV, research publications list and cover letter. For enquiries about the online application process please contact the HR Team, hr@phar.cam.ac.uk

Please quote reference PL34766 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs

Research Assistant/Lab Manager (Part Time, Fixed Term)

Tue, 20/12/2022 - 00:00

Applications are invited for a part-time (0.6 FTE) Research Assistant / Lab Manager position in the laboratory of Prof. Ewan St. John Smith at the Department of Pharmacology, University of Cambridge for an immediate start to work on a Wellcome Trust Discovery Award project in collaboration with Dr David Hughes at the University of Glasgow.

The project, ENDASCOP: Establishing Neuronal Drivers And the Spinal Circuitry of Osteoarthritis Pain, will use a combination of viral and transgenic animal technologies to elucidate the roles of sensory neuron subpopulations in a mouse model of osteoarthritis.

We are looking for a diligent, motivated, and innovative research assistant to join our group who will assist with the lab management aspects of this project; more information about the laboratory is available at www.phar.cam.ac.uk/research/Smith.

The role holder will be based in central Cambridge. The key duties and responsibilities will include, but are not limited to: mouse genotyping / colony management, processing of tissue for histological analysis, assisting with tissue dissection / cell culture, and general administrative activities to support the project, such as ordering reagents and maintaining lab databases.

Successful candidates will likely have demonstrable experience of working in a biological sciences research environment and some aspects of lab management / administration. You must be a careful and methodical worker, paying attention to accuracy. You should be self-motivated and able to work effectively in a team, as well as being able to work independently. Applicants should have, or expect to obtain shortly, a degree in neuroscience or a related discipline.

The funds for this post are available initially for 36-months, but subject to extension to up to 96 months, should both parties agree.

The Department holds an Athena SWAN bronze award, demonstrating a commitment to provide equal opportunities and to advance the representation of women in science subjects. We welcome applications from all qualified candidates irrespective of gender but, as women are currently under-represented at this level in our department, we strongly encourage applications from female candidates. Appointment will be based on merit alone.

Applications will be assessed as and when they are submitted and it is anticipated that initial interviews will take place in February.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries about the position can be made to Prof. Ewan St. John Smith (es336@cam.ac.uk).

The online application is to include your personal details, names and addresses of referees, as well as your CV and cover letter. For enquiries about the online application process please contact the HR Team at hr@phar.cam.ac.uk

Please quote reference PL34768 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Categories: Latest Jobs