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School of the Biological Sciences


Professor, Department of Biochemistry

Sarah Lummis studies the Cys-loop or pentameric ligand-gated ion channel (pLGIC) family of neurotransmitter-gated channels, which provide rapid signal transmission at neuronal synapses. Dysfunctional Cys-loop receptors are responsible for a range of neuronal diseases, including epilepsy, schizophrenia, learning and attention deficit and drug addiction, and they are the targets for muscle relaxants, Alzheimer's drugs, anti-convulsants, tranquilizers, smoking cessation agents and anti-emetics. Learn more


Research Areas

Neurotransmitter receptors
Ligand gated ion channels
Cys-loop receptors
5-HT3 receptors


Molecular biology
Fluorescent imaging
Ligand binding


Research Themes