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School of the Biological Sciences


Group Leader, CRUK Career Development Fellow, Department of Pathology

The Mahata laboratory investigates the mechanism of immune cell-mediated steroidogenesis (a process by which immune cells synthesise and secrete steroid hormones to regulate their function). The laboratory aims to uncover the role of steroid-producing immunocytes in regulating cancer inflammation and immunity, and exploit that knowledge for developing immunotherapy. Learn more


Research Areas

Cancer immunology
Type 2 immunity
Immune cell-mediated steroidogenesis
Steroid-producing immune cells


Flow cytometry
Gene expression analysis (qPCR, RNAseq)
Western blot
Enzyme-linked immunosorbent assay (ELISA)
CRISPR/Cas9 gene knockout

Areas for Collaboration

Steroids detection by chromatography mass-spectrometry
Inflammation driven cancer
Cancer immunosuppression
Type 2 immune responses (e.g. helminth infection, allergies and asthma, arthritis)
Tissue repair
CAR-T cell and adoptive cell therapy


Research Theme