Bidesh Mahata

Group Leader, CRUK Career Development Fellow, Department of Pathology

The Mahata laboratory investigates the mechanism of immune cell-mediated steroidogenesis (a process by which immune cells synthesise and secrete steroid hormones to regulate their function). The laboratory aims to uncover the role of steroid-producing immunocytes in regulating cancer inflammation and immunity, and exploit that knowledge for developing immunotherapy. Learn more

 

Research Areas Steroidogenesis Cancer immunology Type 2 immunity Immune cell-mediated steroidogenesis Steroid-producing immune cells     Techniques Flow cytometry Gene expression analysis (qPCR, RNAseq) Western blot Enzyme-linked immunosorbent assay (ELISA) CRISPR/Cas9 gene knockout     Areas for Collaboration

Steroids detection by chromatography mass-spectrometry
Inflammation driven cancer
Cancer immunosuppression
Type 2 immune responses (e.g. helminth infection, allergies and asthma, arthritis)
Tissue repair
CAR-T cell and adoptive cell therapy

 

Research Theme