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School of the Biological Sciences

 

 

Head of Department, Department of Biochemistry, and Deputy Director, Gurdon Institute 

Eric Miska studies non-coding RNA, epigenetics, and genome stability. Learn more. 

 

Research Areas


Non-coding RNA 
Epigenetics
Genome stability 
 
 
 

Techniques


Caenorhabditis elegans 
Genetic screens
Biochemical approaches
Molecular biology approaches 
 
 
   

 

Research Theme


    

 

Publications

Journal articles

2022

  • Carruthers, M., Edgley, D., Saxon, A., Gabagambi, N., Shechonge, A., Miska, E., Durbin, R., Bridle, J., Turner, G. and Genner, M., 2022. Ecological speciation promoted by divergent regulation of functional genes within African cichlid fishes
    Doi: 10.1101/2022.01.07.475335
  • Navarro, IC., Suen, KM., Bensaddek, D., Tanpure, A., Lamond, A., Balasubramanian, S. and Miska, E., 2022. Identification of putative reader proteins of 5-methylcytosine and its derivatives in <i>Caenorhabditis elegans</i> RNA
    Doi: 10.1101/2022.01.24.477592
  • Vernaz, G., Hudson, AG., Santos, ME., Fischer, B., Carruthers, M., Shechonge, AH., Gabagambi, NP., Tyers, AM., Ngatunga, BP., Malinsky, M., Durbin, R., Turner, GF., Genner, MJ. and Miska, E., 2022. Epigenetic Divergence during Early Stages of Speciation in an African Crater Lake Cichlid Fish Nature Ecology and Evolution,
    Doi: 10.1038/s41559-022-01894-w
  • Erhard, F., Saliba, AE., Lusser, A., Toussaint, C., Hennig, T., Prusty, BK., Kirschenbaum, D., Abadie, K., Miska, EA., Friedel, CC., Amit, I., Micura, R. and Dölken, L., 2022. Time-resolved single-cell RNA-seq using metabolic RNA labelling Nature Reviews Methods Primers, v. 2
    Doi: 10.1038/s43586-022-00157-z
  • Navarro, IC., Suen, KM., Bensaddek, D., Tanpure, A., Lamond, A., Balasubramanian, S. and Miska, EA., 2022. Identification of putative reader proteins of 5-methylcytosine and its derivatives in Caenorhabditis elegans RNA. Wellcome Open Res, v. 7
    Doi: 10.12688/wellcomeopenres.17893.1
  • Efstathiou, S., Ottens, F., Schütter, L-S., Ravanelli, S., Charmpilas, N., Gutschmidt, A., Le Pen, J., Gehring, NH., Miska, EA., Bouças, J. and Hoppe, T., 2022. ER-associated RNA silencing promotes ER quality control. Nat Cell Biol, v. 24
    Doi: 10.1038/s41556-022-01025-4
  • Navarro, IC., Suen, KM., Bensaddek, D., Tanpure, A., Lamond, A., Balasubramanian, S. and Miska, EA., 2022. Identification of putative reader proteins of 5-methylcytosine and its derivatives in <i>Caenorhabditis elegans</i> RNA. Wellcome open research, v. 7
    Doi: http://doi.org/10.12688/wellcomeopenres.17893.1
  • 2021

  • Puntambekar, S., Newhouse, R., San-Miguel, J., Chauhan, R., Vernaz, G., Willis, T., Wayland, MT., Umrania, Y., Miska, EA. and Prabakaran, S., 2021. Author Correction: Evolutionary divergence of novel open reading frames in cichlids speciation. Sci Rep, v. 11
    Doi: http://doi.org/10.1038/s41598-021-88187-7
  • Medhi, R., Price, J., Furlan, G., Gorges, B., Sapetschnig, A. and Miska, E., 2021. RNA uridyl transferases TUT4/7 differentially regulate miRNA variants depending on the cancer cell-type
    Doi: 10.1101/2021.07.12.451846
  • Riehl, K., Riccio, C., Miska, E. and Hemberg, M., 2021. TransposonUltimate: software for transposon classification, annotation and detection
    Doi: 10.1101/2021.04.30.442214
  • Vernaz, G., Hudson, A., Emília Santos, M., Fischer, B., Carruthers, M., Shechonge, A., Gabagambi, N., Tyers, A., Ngatunga, B., Malinsky, M., Durbin, R., Turner, G., Genner, M. and Miska, E., 2021. Epigenetic Divergence during Early Stages of Speciation in an African Crater Lake Cichlid Fish
    Doi: 10.1101/2021.07.30.435319
  • Ramakrishna, NB. and Miska, EA., 2021. Who watches the watchmen? RNAi pathway-derived ribosomal small RNAs burgeon in absence of piRNAs. Dev Cell, v. 56
    Doi: http://doi.org/10.1016/j.devcel.2021.08.002
  • Ramakrishna, NB., Murison, K., Miska, EA. and Leitch, HG., 2021. Epigenetic Regulation during Primordial Germ Cell Development and Differentiation. Sex Dev, v. 15
    Doi: http://doi.org/10.1159/000520412
  • Ziv, O., Farberov, S., Lau, JY., Miska, E., Kudla, G. and Ulitsky, I., 2021. Structural features within the NORAD long noncoding RNA underlie efficient repression of Pumilio activity
    Doi: 10.1101/2021.11.19.469243
  • Medhi, R., Price, J., Furlan, G., Gorges, B., Sapetschnig, A. and Miska, EA., 2021. RNA uridyl transferases TUT4/7 differentially regulate miRNA variants depending on the cancer cell-type. RNA,
    Doi: 10.1261/rna.078976.121
  • Parada, GE., Munita, R., Georgakopoulos-Soares, I., Fernandes, HJR., Kedlian, VR., Metzakopian, E., Andres, ME., Miska, EA. and Hemberg, M., 2021. MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development. Genome Biol, v. 22
    Doi: http://doi.org/10.1186/s13059-020-02246-2
  • Berkyurek, AC., Furlan, G., Lampersberger, L., Beltran, T., Weick, E-M., Nischwitz, E., Cunha Navarro, I., Braukmann, F., Akay, A., Price, J., Butter, F., Sarkies, P. and Miska, EA., 2021. The RNA polymerase II subunit RPB-9 recruits the integrator complex to terminate Caenorhabditis elegans piRNA transcription. EMBO J, v. 40
    Doi: http://doi.org/10.15252/embj.2020105565
  • Sun, L., Li, P., Ju, X., Rao, J., Huang, W., Ren, L., Zhang, S., Xiong, T., Xu, K., Zhou, X., Gong, M., Miska, E., Ding, Q., Wang, J. and Zhang, QC., 2021. In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs. Cell, v. 184
    Doi: http://doi.org/10.1016/j.cell.2021.02.008
  • 2020

  • Svardal, H., Quah, FX., Malinsky, M., Ngatunga, BP., Miska, EA., Salzburger, W., Genner, MJ., Turner, GF. and Durbin, R., 2020. Ancestral Hybridization Facilitated Species Diversification in the Lake Malawi Cichlid Fish Adaptive Radiation. Molecular biology and evolution, v. 37
    Doi: 10.1093/molbev/msz294
  • Lewis, S., Ross, L., Bain, SA., Pahita, E., Smith, SA., Cordaux, R., Miska, EM., Lenhard, B., Jiggins, FM. and Sarkies, P., 2020. Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods
    Doi: 10.1101/2020.01.27.920108
  • Lewis, A., Berkyurek, AC., Greiner, A., Sawh, AN., Vashisht, A., Merrett, S., Flamand, MN., Wohlschlegel, J., Sarov, M., Miska, EA. and Duchaine, TF., 2020. A Family of Argonaute-Interacting Proteins Gates Nuclear RNAi. Mol Cell, v. 78
    Doi: http://doi.org/10.1016/j.molcel.2020.04.007
  • Bista, I., McCarthy, SA., Wood, J., Ning, Z., Detrich Iii, HW., Desvignes, T., Postlethwait, J., Chow, W., Howe, K., Torrance, J., Smith, M., Oliver, K., Vertebrate Genomes Project Consortium, , Miska, EA. and Durbin, R., 2020. The genome sequence of the channel bull blenny, Cottoperca gobio (Günther, 1861). Wellcome Open Res, v. 5
    Doi: 10.12688/wellcomeopenres.16012.1
  • Suen, KM., Braukmann, F., Butler, R., Bensaddek, D., Akay, A., Lin, C-C., Milonaitytė, D., Doshi, N., Sapetschnig, A., Lamond, A., Ladbury, JE. and Miska, E., 2020. DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans Nature Communications,
  • Parada, G., Munita, R., Georgakopoulos-Soares, I., Fernandez, H., Metzakopian, E., Andres, ME., Miska, E. and Hemberg, M., 2020. MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development
    Doi: 10.1101/2020.02.12.945683
  • Chauve, L., Le Pen, J., Hodge, F., Todtenhaupt, P., Biggins, L., Miska, EA., Andrews, S. and Casanueva, O., 2020. High-Throughput Quantitative RT-PCR in Single and Bulk C. elegans Samples Using Nanofluidic Technology. J Vis Exp,
    Doi: http://doi.org/10.3791/61132
  • Berkyurek, A., Furlan, G., Lampersberger, L., Beltran, T., Weick, E-M., Nischwitz, E., Navarro, IC., Braukmann, F., Akay, A., Price, J., Butter, F., Sarkies, P. and Miska, E., 2020. The RNA Polymerase II core subunit RPB-9 directs transcriptional elongation at piRNA loci in<i>Caenorhabditis elegans</i>
    Doi: 10.1101/2020.05.01.070433
  • van Steenwyk, G., Gapp, K., Jawaid, A., Germain, P-L., Manuella, F., Tanwar, DK., Zamboni, N., Gaur, N., Efimova, A., Thumfart, KM., Miska, EA. and Mansuy, IM., 2020. Involvement of circulating factors in the transmission of paternal experiences through the germline. EMBO J, v. 39
    Doi: http://doi.org/10.15252/embj.2020104579
  • Puntambekar, S., Newhouse, R., San-Miguel, J., Chauhan, R., Vernaz, G., Willis, T., Wayland, MT., Umrania, Y., Miska, EA. and Prabakaran, S., 2020. Evolutionary divergence of novel open reading frames in cichlids speciation. Sci Rep, v. 10
    Doi: http://doi.org/10.1038/s41598-020-78555-0
  • 2019

  • Van Haute, L., Lee, S-Y., McCann, B., Powell, C., Bansal, D., Garone, C., Shin, S., Kim, J-S., Frye, M., Gleeson, J., Miska, E., Rhee, H-W. and Minczuk, M., 2019. NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs
    Doi: 10.1101/626960
  • Lin, C-C., Suen, KM., Jeffrey, P-A., Wieteska, L., Stainthorp, A., Seiler, C., Koss, H., Molina-París, C., Miska, E., Ahmed, Z. and Ladbury, J., 2019. Receptor tyrosine kinases regulate signal transduction through a liquid–liquid phase separated state
    Doi: 10.1101/783720
  • Bezler, A., Braukmann, F., West, SM., Duplan, A., Conconi, R., Schütz, F., Gönczy, P., Piano, F., Gunsalus, K., Miska, EA. and Keller, L., 2019. Tissue- and sex-specific small RNAomes reveal sex differences in response to the environment. PLoS Genet, v. 15
    Doi: http://doi.org/10.1371/journal.pgen.1007905
  • Akay, A., Jordan, D., Navarro, IC., Wrzesinski, T., Ponting, CP., Miska, EA. and Haerty, W., 2019. Identification of functional long non-coding RNAs in C. elegans. BMC Biol, v. 17
    Doi: http://doi.org/10.1186/s12915-019-0635-7
  • Maori, E., Navarro, IC., Boncristiani, H., Seilly, DJ., Rudolph, KLM., Sapetschnig, A., Lin, C-C., Ladbury, JE., Evans, JD., Heeney, JL. and Miska, EA., 2019. A Secreted RNA Binding Protein Forms RNA-Stabilizing Granules in the Honeybee Royal Jelly Molecular Cell,
    Doi: 10.1016/j.molcel.2019.03.010
  • Matsushima, W., Herzog, VA., Neumann, T., Gapp, K., Zuber, J., Ameres, SL. and Miska, EA., 2019. Publisher Correction: Sequencing cell-type-specific transcriptomes with SLAM-ITseq. Nat Protoc, v. 14
    Doi: http://doi.org/10.1038/s41596-019-0224-9
  • LeBoeuf, AC., Waridel, P., Brent, CS., Gonçalves, AN., Menin, L., Ortiz, D., Riba-Grognuz, O., Koto, A., Soares, ZG., Privman, E., Miska, EA., Benton, R. and Keller, L., 2019. Oral transfer of chemical cues, growth proteins and hormones in social insects. Elife, v. 8
    Doi: http://doi.org/10.7554/eLife.51082
  • 2018

  • Frézal, L., Demoinet, E., Braendle, C., Miska, E. and Félix, M-A., 2018. Natural Genetic Variation in a Multigenerational Phenotype in C. elegans. Curr Biol, v. 28
    Doi: http://doi.org/10.1016/j.cub.2018.05.091
  • Malinsky, M., Svardal, H., Tyers, AM., Miska, EA., Genner, MJ., Turner, GF. and Durbin, R., 2018. Whole-genome sequences of Malawi cichlids reveal multiple radiations interconnected by gene flow. Nat Ecol Evol, v. 2
    Doi: 10.1038/s41559-018-0717-x
  • Weng, C., Kosalka, J., Berkyurek, AC., Stempor, P., Feng, X., Mao, H., Zeng, C., Li, W-J., Yan, Y-H., Dong, M-Q., Morero, NR., Zuliani, C., Barabas, O., Ahringer, J., Guang, S. and Miska, EA., 2018. The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans. Genes and Development,
    Doi: 10.1101/gad.319293.118
  • Lewis, SH., Quarles, KA., Yang, Y., Tanguy, M., Frezal, L., Smith, SA., Sharma, PP., Cordaux, R., Gilbert, C., Giraud, I., Collins, DH., Zamore, PD., Miska, EA., Sarkies, P. and Jiggins, FM., 2018. Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements Nature Ecology & Evolution, v. 2
    Doi: 10.1038/s41559-017-0403-4
  • 2017

  • Cording, A., Gormally, M., Bond, PJ., Carrington, M., Balasubramanian, S., Miska, EA. and Thomas, B., 2017. Selective inhibitors of trypanosomal uridylyl transferase RET1 establish druggability of RNA post-transcriptional modifications. RNA Biol, v. 14
    Doi: 10.1080/15476286.2015.1137422
  • Huber, SM., van Delft, P., Tanpure, A., Miska, EA. and Balasubramanian, S., 2017. 2'-$\textit{0}$-Methyl-5-hydroxymethylcytidine: A Second Oxidative Derivative of 5-Methylcytidine in RNA Journal of the American Chemical Society, v. 139
    Doi: http://doi.org/10.1021/jacs.6b12180
  • Bellon, A., Iyer, A., Bridi, S., Lee, FCY., Ovando-Vázquez, C., Corradi, E., Longhi, S., Roccuzzo, M., Strohbuecker, S., Naik, S., Sarkies, P., Miska, E., Abreu-Goodger, C., Holt, CE. and Baudet, M-L., 2017. miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA Cell Reports, v. 18
    Doi: http://doi.org/10.1016/j.celrep.2016.12.093
  • Balasubramanian, S., van Delft, P., Akay, A., Bueschl, C., Rudolph, K., Domenico, T., Schuhmacher, R. and Miska, E., 2017. The profile and dynamics of RNA modifications in animals Chembiochem : a European journal of chemical biology, v. 18
    Doi: http://doi.org/10.1002/cbic.201700093
  • McMurchy, AN., Stempor, P., Gaarenstroom, T., Wysolmerski, B., Dong, Y., Aussianikava, D., Appert, A., Huang, N., Kolasinska-Zwierz, P., Sapetschnig, A., Miska, EA. and Ahringer, J., 2017. A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress. Elife, v. 6
    Doi: 10.7554/eLife.21666
  • Akay, A., Di Domenico, T., Suen, KM., Nabih, A., Parada, GE., Larance, M., Medhi, R., Berkyurek, , Zhang, X., Wedeles, CJ., Rudolph, , Engelhardt, J., Hemberg, M., Ma, P., Lamond, AI., Claycomb, JM. and Miska, , 2017. The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription Developmental Cell, v. 42
    Doi: http://doi.org/10.1016/j.devcel.2017.07.002
  • McMurchy, AN., Stempor, P., Gaarenstroom, T., Wysolmerski, B., Dong, Y., Aussianikava, D., Appert, A., Huang, N., Kolasinska-Zwierz, P., Sapetschnig, A., Miska, EA. and Ahringer, J., 2017. Correction: A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress. Elife, v. 6
    Doi: 10.7554/eLife.32516
  • 2016

  • Gapp, K. and Miska, EA., 2016. tRNA fragments: novel players in intergenerational inheritance. Cell Res, v. 26
    Doi: 10.1038/cr.2016.24
  • Rainey, SM., Martinez, J., McFarlane, M., Juneja, P., Sarkies, P., Lulla, A., Schnettler, E., Varjak, M., Merits, A., Miska, EA., Jiggins, FM. and Kohl, A., 2016. Wolbachia Blocks Viral Genome Replication Early in Infection without a Transcriptional Response by the Endosymbiont or Host Small RNA Pathways. PLoS Pathog, v. 12
    Doi: 10.1371/journal.ppat.1005536
  • Lightfoot, HL., Miska, EA. and Balasubramanian, S., 2016. Identification of small molecule inhibitors of the Lin28-mediated blockage of pre-let-7g processing Organic and Biomolecular Chemistry, v. 14
    Doi: http://doi.org/10.1039/c6ob01945e
  • LeBoeuf, AC., Waridel, P., Brent, CS., Gonçalves, AN., Menin, L., Ortiz, D., Riba-Grognuz, O., Koto, A., Soares, ZG., Privman, E., Miska, EA., Benton, R. and Keller, L., 2016. Oral transfer of chemical cues, growth proteins and hormones in social insects. Elife, v. 5
    Doi: http://doi.org/10.7554/eLife.20375
  • 2015

  • Huber, SM., van Delft, P., Mendil, L., Bachman, M., Smollett, K., Werner, F., Miska, EA. and Balasubramanian, S., 2015. Formation and abundance of 5-hydroxymethylcytosine in RNA. Chembiochem, v. 16
    Doi: http://doi.org/10.1002/cbic.201500013
  • Sarkies, P., Selkirk, ME., Jones, JT., Blok, V., Boothby, T., Goldstein, B., Hanelt, B., Ardila-Garcia, A., Fast, NM., Schiffer, PM., Kraus, C., Taylor, MJ., Koutsovoulos, G., Blaxter, ML. and Miska, EA., 2015. Ancient and novel small RNA pathways compensate for the loss of piRNAs in multiple independent nematode lineages. PLoS Biol, v. 13
    Doi: 10.1371/journal.pbio.1002061
  • Sapetschnig, A., Sarkies, P., Lehrbach, NJ. and Miska, EA., 2015. Tertiary siRNAs mediate paramutation in C. elegans. PLoS Genet, v. 11
    Doi: 10.1371/journal.pgen.1005078
  • Akay, A., Sarkies, P. and Miska, EA., 2015. E. coli OxyS non-coding RNA does not trigger RNAi in C. elegans. Sci Rep, v. 5
    Doi: 10.1038/srep09597
  • Ashe, A., Sarkies, P., Le Pen, J., Tanguy, M. and Miska, EA., 2015. Antiviral RNA Interference against Orsay Virus Is neither Systemic nor Transgenerational in Caenorhabditis elegans. J Virol, v. 89
    Doi: http://doi.org/10.1128/JVI.03664-14
  • Malinsky, M., Challis, RJ., Tyers, AM., Schiffels, S., Terai, Y., Ngatunga, BP., Miska, EA., Durbin, R., Genner, MJ. and Turner, GF., 2015. Genomic islands of speciation separate cichlid ecomorphs in an East African crater lake. Science, v. 350
    Doi: 10.1126/science.aac9927
  • 2014

  • Bassett, AR., Akhtar, A., Barlow, DP., Bird, AP., Brockdorff, N., Duboule, D., Ephrussi, A., Ferguson-Smith, AC., Gingeras, TR., Haerty, W., Higgs, DR., Miska, EA. and Ponting, CP., 2014. Considerations when investigating lncRNA function in vivo. Elife, v. 3
    Doi: 10.7554/eLife.03058
  • Brawand, D., Wagner, CE., Li, YI., Malinsky, M., Keller, I., Fan, S., Simakov, O., Ng, AY., Lim, ZW., Bezault, E., Turner-Maier, J., Johnson, J., Alcazar, R., Noh, HJ., Russell, P., Aken, B., Alföldi, J., Amemiya, C., Azzouzi, N., Baroiller, J-F., Barloy-Hubler, F., Berlin, A., Bloomquist, R., Carleton, KL., Conte, MA., D'Cotta, H., Eshel, O., Gaffney, L., Galibert, F., Gante, HF., Gnerre, S., Greuter, L., Guyon, R., Haddad, NS., Haerty, W., Harris, RM., Hofmann, HA., Hourlier, T., Hulata, G., Jaffe, DB., Lara, M., Lee, AP., MacCallum, I., Mwaiko, S., Nikaido, M., Nishihara, H., Ozouf-Costaz, C., Penman, DJ., Przybylski, D., Rakotomanga, M., Renn, SCP., Ribeiro, FJ., Ron, M., Salzburger, W., Sanchez-Pulido, L., Santos, ME., Searle, S., Sharpe, T., Swofford, R., Tan, FJ., Williams, L., Young, S., Yin, S., Okada, N., Kocher, TD., Miska, EA., Lander, ES., Venkatesh, B., Fernald, RD., Meyer, A., Ponting, CP., Streelman, JT., Lindblad-Toh, K., Seehausen, O. and Di Palma, F., 2014. The genomic substrate for adaptive radiation in African cichlid fish. Nature, v. 513
    Doi: 10.1038/nature13726
  • Weick, E-M. and Miska, EA., 2014. piRNAs: from biogenesis to function. Development, v. 141
    Doi: 10.1242/dev.094037
  • Sakaguchi, A., Sarkies, P., Simon, M., Doebley, A-L., Goldstein, LD., Hedges, A., Ikegami, K., Alvares, SM., Yang, L., LaRocque, JR., Hall, J., Miska, EA. and Ahmed, S., 2014. Caenorhabditis elegans RSD-2 and RSD-6 promote germ cell immortality by maintaining small interfering RNA populations. Proc Natl Acad Sci U S A, v. 111
    Doi: 10.1073/pnas.1406131111
  • Peden, AS., Mac, P., Fei, YJ., Castro, C., Jiang, G., Murfitt, KJ., Miska, EA., Griffin, JL., Ganapathy, V. and Jorgensen, EM., 2014. Erratum: Betaine acts on a ligand-gated ion channel in the nervous system of the nematode C. elegans. Nat Neurosci, v. 17
    Doi: http://doi.org/10.1038/nn1214-1840f
  • Harding, JL., Horswell, S., Heliot, C., Armisen, J., Zimmerman, LB., Luscombe, NM., Miska, EA. and Hill, CS., 2014. Small RNA profiling of Xenopus embryos reveals novel miRNAs and a new class of small RNAs derived from intronic transposable elements. Genome Res, v. 24
    Doi: 10.1101/gr.144469.112
  • Peden, AS., Mac, P., Fei, Y-J., Castro, C., Jiang, G., Murfitt, KJ., Miska, EA., Griffin, JL., Ganapathy, V. and Jorgensen, EM., 2014. Betaine acts on a ligand-gated ion channel in the nervous system of the nematode C. elegans (vol 16, pg 1794, 2013) NATURE NEUROSCIENCE, v. 17
    Doi: 10.1038/nn1214-1840f
  • Weick, E-M., Sarkies, P., Silva, N., Chen, RA., Moss, SMM., Cording, AC., Ahringer, J., Martinez-Perez, E. and Miska, EA., 2014. PRDE-1 is a nuclear factor essential for the biogenesis of Ruby motif-dependent piRNAs in C. elegans. Genes Dev, v. 28
    Doi: 10.1101/gad.238105.114
  • Gapp, K., Jawaid, A., Sarkies, P., Bohacek, J., Pelczar, P., Prados, J., Farinelli, L., Miska, E. and Mansuy, IM., 2014. Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice. Nat Neurosci, v. 17
    Doi: 10.1038/nn.3695
  • Simon, M., Sarkies, P., Ikegami, K., Doebley, A-L., Goldstein, LD., Mitchell, J., Sakaguchi, A., Miska, EA. and Ahmed, S., 2014. Reduced insulin/IGF-1 signaling restores germ cell immortality to Caenorhabditis elegans Piwi mutants. Cell Rep, v. 7
    Doi: 10.1016/j.celrep.2014.03.056
  • Sapetschnig, A. and Miska, EA., 2014. Getting a grip on piRNA cluster transcription. Cell, v. 157
    Doi: 10.1016/j.cell.2014.05.022
  • Sarkies, P. and Miska, EA., 2014. Small RNAs break out: the molecular cell biology of mobile small RNAs. Nat Rev Mol Cell Biol, v. 15
    Doi: 10.1038/nrm3840
  • 2013

  • Castro, C., Krumsiek, J., Lehrbach, NJ., Murfitt, SA., Miska, EA. and Griffin, JL., 2013. A study of Caenorhabditis elegans DAF-2 mutants by metabolomics and differential correlation networks. Mol Biosyst, v. 9
    Doi: http://doi.org/10.1039/c3mb25539e
  • Dvinge, H., Git, A., Gräf, S., Salmon-Divon, M., Curtis, C., Sottoriva, A., Zhao, Y., Hirst, M., Armisen, J., Miska, EA., Chin, S-F., Provenzano, E., Turashvili, G., Green, A., Ellis, I., Aparicio, S. and Caldas, C., 2013. The shaping and functional consequences of the microRNA landscape in breast cancer. Nature, v. 497
    Doi: http://doi.org/10.1038/nature12108
  • Sarkies, P., Ashe, A., Le Pen, J., McKie, MA. and Miska, EA., 2013. Competition between virus-derived and endogenous small RNAs regulates gene expression in Caenorhabditis elegans. Genome Res, v. 23
    Doi: 10.1101/gr.153296.112
  • Sarkies, P. and Miska, EA., 2013. RNAi pathways in the recognition of foreign RNA: antiviral responses and host-parasite interactions in nematodes. Biochem Soc Trans, v. 41
    Doi: 10.1042/BST20130021
  • Sarkies, P. and Miska, EA., 2013. Molecular biology. Is there social RNA? Science, v. 341
    Doi: http://doi.org/10.1126/science.1243175
  • Mok, Y., Schwierzeck, V., Thomas, DC., Vigorito, E., Rayner, TF., Jarvis, LB., Prosser, HM., Bradley, A., Withers, DR., Mårtensson, I-L., Corcoran, LM., Blenkiron, C., Miska, EA., Lyons, PA. and Smith, KGC., 2013. MiR-210 is induced by Oct-2, regulates B cells, and inhibits autoantibody production. J Immunol, v. 191
    Doi: 10.4049/jimmunol.1301289
  • Ashe, A., Bélicard, T., Le Pen, J., Sarkies, P., Frézal, L., Lehrbach, NJ., Félix, M-A. and Miska, EA., 2013. A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity. Elife, v. 2
    Doi: 10.7554/eLife.00994
  • Tanguy, M. and Miska, EA., 2013. Antiviral RNA interference in animals: piecing together the evidence. Nat Struct Mol Biol, v. 20
    Doi: http://doi.org/10.1038/nsmb.2708
  • Peden, AS., Mac, P., Fei, Y-J., Castro, C., Jiang, G., Murfitt, KJ., Miska, EA., Griffin, JL., Ganapathy, V. and Jorgensen, EM., 2013. Betaine acts on a ligand-gated ion channel in the nervous system of the nematode C. elegans. Nat Neurosci, v. 16
    Doi: 10.1038/nn.3575
  • Akay, A., Craig, A., Lehrbach, N., Larance, M., Pourkarimi, E., Wright, JE., Lamond, A., Miska, E. and Gartner, A., 2013. RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans. Open Biol, v. 3
    Doi: 10.1098/rsob.130151
  • 2012

  • Castro, C., Sar, F., Shaw, WR., Mishima, M., Miska, EA. and Griffin, JL., 2012. A metabolomic strategy defines the regulation of lipid content and global metabolism by Δ9 desaturases in Caenorhabditis elegans. BMC Genomics, v. 13
    Doi: http://doi.org/10.1186/1471-2164-13-36
  • Vasquez-Rifo, A., Jannot, G., Armisen, J., Labouesse, M., Bukhari, SIA., Rondeau, EL., Miska, EA. and Simard, MJ., 2012. Developmental characterization of the microRNA-specific C. elegans Argonautes alg-1 and alg-2. PLoS One, v. 7
    Doi: http://doi.org/10.1371/journal.pone.0033750
  • Jovanovic, M., Reiter, L., Clark, A., Weiss, M., Picotti, P., Rehrauer, H., Frei, A., Neukomm, LJ., Kaufman, E., Wollscheid, B., Simard, MJ., Miska, EA., Aebersold, R., Gerber, AP. and Hengartner, MO., 2012. RIP-chip-SRM--a new combinatorial large-scale approach identifies a set of translationally regulated bantam/miR-58 targets in C. elegans. Genome Res, v. 22
    Doi: http://doi.org/10.1101/gr.133330.111
  • Bagijn, MP., Goldstein, LD., Sapetschnig, A., Weick, E-M., Bouasker, S., Lehrbach, NJ., Simard, MJ. and Miska, EA., 2012. Function, targets, and evolution of Caenorhabditis elegans piRNAs. Science, v. 337
    Doi: http://doi.org/10.1126/science.1220952
  • Ashe, A., Sapetschnig, A., Weick, E-M., Mitchell, J., Bagijn, MP., Cording, AC., Doebley, A-L., Goldstein, LD., Lehrbach, NJ., Le Pen, J., Pintacuda, G., Sakaguchi, A., Sarkies, P., Ahmed, S. and Miska, EA., 2012. piRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegans. Cell, v. 150
    Doi: http://doi.org/10.1016/j.cell.2012.06.018
  • Kamminga, LM., van Wolfswinkel, JC., Luteijn, MJ., Kaaij, LJT., Bagijn, MP., Sapetschnig, A., Miska, EA., Berezikov, E. and Ketting, RF., 2012. Differential impact of the HEN1 homolog HENN-1 on 21U and 26G RNAs in the germline of Caenorhabditis elegans. PLoS Genet, v. 8
    Doi: http://doi.org/10.1371/journal.pgen.1002702
  • Lehrbach, NJ., Castro, C., Murfitt, KJ., Abreu-Goodger, C., Griffin, JL. and Miska, EA., 2012. Post-developmental microRNA expression is required for normal physiology, and regulates aging in parallel to insulin/IGF-1 signaling in C. elegans. RNA, v. 18
    Doi: http://doi.org/10.1261/rna.035402.112
  • Armisen, J., Shaw, WR. and Miska, EA., 2012. Identification and Expression Profiling of Small RNA Populations Using High-Throughput Sequencing
    Doi: http://doi.org/10.1002/9783527644582.ch8
  • 2011

  • Lehrbach, NJ. and Miska, EA., 2011. Regulation of pre-miRNA Processing. Adv Exp Med Biol, v. 700
    Doi: http://doi.org/10.1007/978-1-4419-7823-3_7
  • Lightfoot, HL., Bugaut, A., Armisen, J., Lehrbach, NJ., Miska, EA. and Balasubramanian, S., 2011. A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing. Biochemistry, v. 50
    Doi: http://doi.org/10.1021/bi200851d
  • Félix, M-A., Ashe, A., Piffaretti, J., Wu, G., Nuez, I., Bélicard, T., Jiang, Y., Zhao, G., Franz, CJ., Goldstein, LD., Sanroman, M., Miska, EA. and Wang, D., 2011. Natural and experimental infection of Caenorhabditis nematodes by novel viruses related to nodaviruses. PLoS Biol, v. 9
    Doi: http://doi.org/10.1371/journal.pbio.1000586
  • 2010

  • Jovanovic, M., Reiter, L., Picotti, P., Lange, V., Bogan, E., Hurschler, BA., Blenkiron, C., Lehrbach, NJ., Ding, XC., Weiss, M., Schrimpf, SP., Miska, EA., Großhans, H., Aebersold, R. and Hengartner, MO., 2010. Erratum: A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans (Nature Methods (2010) 7 (837-842)) Nature Methods, v. 7
    Doi: http://doi.org/10.1038/nmeth1210-1025a
  • Shaw, WR., Armisen, J., Lehrbach, NJ. and Miska, EA., 2010. The conserved miR-51 microRNA family is redundantly required for embryonic development and pharynx attachment in Caenorhabditis elegans. Genetics, v. 185
    Doi: http://doi.org/10.1534/genetics.110.117515
  • Clark, AM., Goldstein, LD., Tevlin, M., Tavaré, S., Shaham, S. and Miska, EA., 2010. The microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans. Nucleic Acids Res, v. 38
    Doi: http://doi.org/10.1093/nar/gkq083
  • Kaufman, EJ. and Miska, EA., 2010. The microRNAs of Caenorhabditis elegans. Semin Cell Dev Biol, v. 21
    Doi: http://doi.org/10.1016/j.semcdb.2010.07.001
  • Jovanovic, M., Reiter, L., Picotti, P., Lange, V., Bogan, E., Hurschler, BA., Blenkiron, C., Lehrbach, NJ., Ding, XC., Weiss, M., Schrimpf, SP., Miska, EA., Grosshans, H., Aebersold, R. and Hengartner, MO., 2010. A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans. Nat Methods, v. 7
    Doi: http://doi.org/10.1038/nmeth.1504
  • Hanina, SA., Mifsud, W., Down, TA., Hayashi, K., O'Carroll, D., Lao, KQ., Miska, EA. and Surani, MA., 2010. Genome-Wide Identification of Targets and Function of Individual MicroRNAs in Mouse Embryonic Stem Cells PLOS GENET, v. 6
    Doi: 10.1371/journal.pgen.1001163
  • Jovanovic, M., Reiter, L., Picotti, P., Lange, V., Bogan, E., Hurschler, BA., Blenkiron, C., Lehrbach, NJ., Ding, XC., Weiss, M., Schrimpf, SP., Miska, EA., Grosshans, H., Aebersold, R. and Hengartner, MO., 2010. A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans (vol 7, pg 837, 2010) NAT METHODS, v. 7
    Doi: http://doi.org/10.1038/nmeth1210-1025a
  • Lehrbach, NJ. and Miska, EA., 2010. REGULATION OF pre-miRNA PROCESSING ADV EXP MED BIOL, v. 700
  • 2009

  • Wilczynska, A., Minshall, N., Armisen, J., Miska, EA. and Standart, N., 2009. Two Piwi proteins, Xiwi and Xili, are expressed in the Xenopus female germline. RNA, v. 15
    Doi: http://doi.org/10.1261/rna.1422509
  • Armisen, J., Gilchrist, MJ., Wilczynska, A., Standart, N. and Miska, EA., 2009. Abundant and dynamically expressed miRNAs, piRNAs, and other small RNAs in the vertebrate Xenopus tropicalis. Genome Res, v. 19
    Doi: http://doi.org/10.1101/gr.093054.109
  • Lehrbach, NJ., Armisen, J., Lightfoot, HL., Murfitt, KJ., Bugaut, A., Balasubramanian, S. and Miska, EA., 2009. LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans. Nat Struct Mol Biol, v. 16
    Doi: http://doi.org/10.1038/nsmb.1675
  • Avril-Sassen, S., Goldstein, LD., Stingl, J., Blenkiron, C., Le Quesne, J., Spiteri, I., Karagavriilidou, K., Watson, CJ., Tavaré, S., Miska, EA. and Caldas, C., 2009. Characterisation of microRNA expression in post-natal mouse mammary gland development. BMC Genomics, v. 10
    Doi: 10.1186/1471-2164-10-548
  • 2008

  • Sassen, S., Miska, EA. and Caldas, C., 2008. MicroRNA: implications for cancer. Virchows Arch, v. 452
    Doi: http://doi.org/10.1007/s00428-007-0532-2
  • Lykke-Andersen, K., Gilchrist, MJ., Grabarek, JB., Das, P., Miska, E. and Zernicka-Goetz, M., 2008. Maternal Argonaute 2 is essential for early mouse development at the maternal-zygotic transition. Mol Biol Cell, v. 19
    Doi: http://doi.org/10.1091/mbc.e08-02-0219
  • Hayashi, K., Chuva de Sousa Lopes, SM., Kaneda, M., Tang, F., Hajkova, P., Lao, K., O'Carroll, D., Das, PP., Tarakhovsky, A., Miska, EA. and Surani, MA., 2008. MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis. PLoS One, v. 3
    Doi: 10.1371/journal.pone.0001738
  • Miska, EA., 2008. MicroRNAs--keeping cells in formation. Nat Cell Biol, v. 10
    Doi: http://doi.org/10.1038/ncb0508-501
  • Choi, PS., Zakhary, L., Choi, W-Y., Caron, S., Alvarez-Saavedra, E., Miska, EA., McManus, M., Harfe, B., Giraldez, AJ., Horvitz, HR., Schier, AF. and Dulac, C., 2008. Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron, v. 57
    Doi: http://doi.org/10.1016/j.neuron.2007.11.018
  • Lehrbach, NJ. and Miska, EA., 2008. Functional genomic, computational and proteomic analysis of C. elegans microRNAs. Brief Funct Genomic Proteomic, v. 7
    Doi: http://doi.org/10.1093/bfgp/eln024
  • Atherton, HJ., Jones, OAH., Malik, S., Miska, EA. and Griffin, JL., 2008. A comparative metabolomic study of NHR-49 in Caenorhabditis elegans and PPAR-alpha in the mouse. FEBS Lett, v. 582
    Doi: http://doi.org/10.1016/j.febslet.2008.04.020
  • Das, PP., Bagijn, MP., Goldstein, LD., Woolford, JR., Lehrbach, NJ., Sapetschnig, A., Buhecha, HR., Gilchrist, MJ., Howe, KL., Stark, R., Matthews, N., Berezikov, E., Ketting, RF., Tavaré, S. and Miska, EA., 2008. Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline. Mol Cell, v. 31
    Doi: http://doi.org/10.1016/j.molcel.2008.06.003
  • 2007

  • Miska, EA., Alvarez-Saavedra, E., Abbott, AL., Lau, NC., Hellman, AB., McGonagle, SM., Bartel, DP., Ambros, VR. and Horvitz, HR., 2007. Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. PLoS genetics, v. 3
    Doi: http://doi.org/10.1371/journal.pgen.0030215
  • Blenkiron, C. and Miska, EA., 2007. miRNAs in cancer: approaches, aetiology, diagnostics and therapy. Hum Mol Genet, v. 16 Spec No 1
    Doi: http://doi.org/10.1093/hmg/ddm056
  • Lujambio, A., Ropero, S., Ballestar, E., Fraga, MF., Cerrato, C., Setién, F., Casado, S., Suarez-Gauthier, A., Sanchez-Cespedes, M., Git, A., Spiteri, I., Das, PP., Caldas, C., Miska, E. and Esteller, M., 2007. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res, v. 67
    Doi: http://doi.org/10.1158/0008-5472.CAN-06-4218
  • Rodriguez, A., Vigorito, E., Clare, S., Warren, MV., Couttet, P., Soond, DR., van Dongen, S., Grocock, RJ., Das, PP., Miska, EA., Vetrie, D., Okkenhaug, K., Enright, AJ., Dougan, G., Turner, M. and Bradley, A., 2007. Requirement of bic/microRNA-155 for normal immune function. Science, v. 316
    Doi: 10.1126/science.1139253
  • O'Carroll, D., Mecklenbrauker, I., Das, PP., Santana, A., Koenig, U., Enright, AJ., Miska, EA. and Tarakhovsky, A., 2007. A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway. Genes Dev, v. 21
    Doi: 10.1101/gad.1565607
  • Miska, EA., Alvarez-Saavedra, E., Abbott, AL., Lau, NC., Hellman, AB., McGonagle, SM., Bartel, DP., Ambros, VR. and Horvitz, HR., 2007. Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. PLoS Genet, v. 3
    Doi: http://doi.org/10.1371/journal.pgen.0030215
  • Vigorito, E., Perks, KL., Abreu-Goodger, C., Bunting, S., Xiang, Z., Kohlhaas, S., Das, PP., Miska, EA., Rodriguez, A., Bradley, A., Smith, KGC., Rada, C., Enright, AJ., Toellner, K-M., Maclennan, ICM. and Turner, M., 2007. microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity, v. 27
    Doi: 10.1016/j.immuni.2007.10.009
  • Miska, EA. and Ahringer, J., 2007. RNA interference has second helpings. Nat Biotechnol, v. 25
    Doi: 10.1038/nbt0307-302
  • Blenkiron, C., Goldstein, LD., Thorne, NP., Spiteri, I., Chin, S-F., Dunning, MJ., Barbosa-Morais, NL., Teschendorff, AE., Green, AR., Ellis, IO., Tavaré, S., Caldas, C. and Miska, EA., 2007. MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol, v. 8
    Doi: http://doi.org/10.1186/gb-2007-8-10-r214
  • Lujambic, A., Ropero, S., Ballestar, E., Fraga, MF., Cerrato, C., Setien, F., Casado, S., Suarez-Gauthier, A., Sanchez-Cespedes, M., Git, A., Spiteri, I., Das, PP., Caldas, C., Miska, E. and Esteller, M., 2007. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells (vol 67, pg 1424, 2007) CANCER RES, v. 67
  • 2006

  • Abbott, AL., Alvarez-Saavedra, E., Miska, EA., Lau, NC., Bartel, DP., Horvitz, HR. and Ambros, V., 2006. The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans (vol 9, pg 403, 2005) DEV CELL, v. 10
    Doi: http://doi.org/10.1016/j.devcel.2006.01.010
  • Abbott, AL., Alvarez-Saavedra, E., Miska, EA., Lau, NC., Bartel, DP., Horvitz, HR. and Ambros, V., 2006. Erratum: The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans (Developmental Cell (2005) vol. 9 (403-414) 10.1016/ j.devcel.2006.01.010.) Developmental Cell, v. 10
    Doi: http://doi.org/10.1016/j.devcel.2006.01.010
  • 2005

  • Alvarez-Saavedra, EA. and Miska, EA., 2005. Caenorhabditis elegans and friends in Los Angeles. Genome Biol, v. 6
    Doi: 10.1186/gb-2005-6-11-358
  • Wienholds, E., Kloosterman, WP., Miska, E., Alvarez-Saavedra, E., Berezikov, E., de Bruijn, E., Horvitz, HR., Kauppinen, S. and Plasterk, RHA., 2005. MicroRNA expression in zebrafish embryonic development. Science, v. 309
    Doi: http://doi.org/10.1126/science.1114519
  • Wienholds, E., Kloosterman, WP., Miska, E., Alvarez-Saavedra, E., Berezikov, E., de Bruijn, E., Horvitz, HR., Kauppinen, S. and Plasterk, RHA., 2005. MicroRNA expression in zebrafish embryonic development MECH DEVELOP, v. 122
  • Wienholds, E., Kloosterman, WP., Miska, E., Alvarez-Saavedra, E., Berezikov, E., De Bruijn, E., Horvitz, HR., Kauppinen, S. and Plasterk, RHA., 2005. Cell biology: MicroRNA expression in zebrafish embryonic development Science, v. 309
    Doi: http://doi.org/10.1126/science.1114519
  • Abbott, AL., Alvarez-Saavedra, E., Miska, EA., Lau, NC., Bartel, DP., Horvitz, HR. and Ambros, V., 2005. The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev Cell, v. 9
    Doi: http://doi.org/10.1016/j.devcel.2005.07.009
  • Lu, J., Getz, G., Miska, EA., Alvarez-Saavedra, E., Lamb, J., Peck, D., Sweet-Cordero, A., Ebert, BL., Mak, RH., Ferrando, AA., Downing, JR., Jacks, T., Horvitz, HR. and Golub, TR., 2005. MicroRNA expression profiles classify human cancers. Nature, v. 435
    Doi: http://doi.org/10.1038/nature03702
  • Alvarez-Garcia, I. and Miska, EA., 2005. MicroRNA functions in animal development and human disease. Development, v. 132
    Doi: http://doi.org/10.1242/dev.02073
  • Miska, EA., 2005. How microRNAs control cell division, differentiation and death. Curr Opin Genet Dev, v. 15
    Doi: http://doi.org/10.1016/j.gde.2005.08.005
  • Alvarez-Saavedra, EA. and Miska, EA., 2005. Caenorhabditis elegans and friends in Los Angeles. Genome biology, v. 6
  • 2004

  • Miska, EA., Alvarez-Saavedra, E., Townsend, M., Yoshii, A., Sestan, N., Rakic, P., Constantine-Paton, M. and Horvitz, HR., 2004. Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol, v. 5
    Doi: http://doi.org/10.1186/gb-2004-5-9-r68
  • 2002

  • Kirsh, O., Seeler, J-S., Pichler, A., Gast, A., Müller, S., Miska, E., Mathieu, M., Harel-Bellan, A., Kouzarides, T., Melchior, F. and Dejean, A., 2002. The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase. EMBO J, v. 21
    Doi: 10.1093/emboj/21.11.2682
  • Wolf, D., Rodova, M., Miska, EA., Calvet, JP. and Kouzarides, T., 2002. Acetylation of beta-catenin by CREB-binding protein (CBP). J Biol Chem, v. 277
    Doi: 10.1074/jbc.M201196200
  • 2001

  • Bannister, AJ., Zegerman, P., Partridge, JF., Miska, EA., Thomas, JO., Allshire, RC. and Kouzarides, T., 2001. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain NATURE, v. 410
  • Miska, EA., Langley, E., Wolf, D., Karlsson, C., Pines, J. and Kouzarides, T., 2001. Differential localization of HDAC4 orchestrates muscle differentiation NUCLEIC ACIDS RES, v. 29
  • 2000

  • Huang, EY., Zhang, J., Miska, EA., Guenther, MG., Kouzarides, T. and Lazar, MA., 2000. Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway. Genes Dev, v. 14
  • Grimes, JA., Nielsen, SJ., Battaglioli, E., Miska, EA., Speh, JC., Berry, DL., Atouf, F., Holdener, BC., Mandel, G. and Kouzarides, T., 2000. The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex. J Biol Chem, v. 275
    Doi: 10.1074/jbc.275.13.9461
  • Bannister, AJ., Miska, EA., Görlich, D. and Kouzarides, T., 2000. Acetylation of importin-alpha nuclear import factors by CBP/p300. Curr Biol, v. 10
    Doi: 10.1016/s0960-9822(00)00445-0
  • Bannister, AJ. and Miska, EA., 2000. Regulation of gene expression by transcription factor acetylation. Cell Mol Life Sci, v. 57
    Doi: http://doi.org/10.1007/pl00000758
  • 1999

  • Sparrow, DB., Miska, EA., Langley, E., Reynaud-Deonauth, S., Kotecha, S., Towers, N., Spohr, G., Kouzarides, T. and Mohun, TJ., 1999. MEF-2 function is modified by a novel co-repressor, MITR. EMBO J, v. 18
    Doi: 10.1093/emboj/18.18.5085
  • Miska, EA., Karlsson, C., Langley, E., Nielsen, SJ., Pines, J. and Kouzarides, T., 1999. HDAC4 deacetylase associates with and represses the MEF2 transcription factor. EMBO J, v. 18
    Doi: 10.1093/emboj/18.18.5099
  • Brehm, A., Nielsen, SJ., Miska, EA., McCance, DJ., Reid, JL., Bannister, AJ. and Kouzarides, T., 1999. The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth. EMBO J, v. 18
    Doi: 10.1093/emboj/18.9.2449
  • 1998

  • Brehm, A., Miska, EA., McCance, DJ., Reid, JL., Bannister, AJ. and Kouzarides, T., 1998. Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature, v. 391
    Doi: 10.1038/35404
  • Matsushima, W., Herzog, V., Neumann, T., Gapp, K., Zuber, J., Ameres, S. and Miska, E., SLAM-ITseq: Sequencing cell type-specific transcriptomes without cell sorting Development,
  • Burton, N., Riccio, C., Dallaire, A., Price, J., Jenkins, B., Koulman, A. and Miska, E., Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection Nature Communications,
    Doi: http://doi.org/10.1101/675132
  • Ziv, O., Gabryelska, MM., Lun, ATL., Gebert, LFR., Sheu-Gruttadauria, J., Meredith, LW., Liu, Z-Y., Kwok, CK., Qin, C-F., Macrae, IJ., Goodfellow, I., Marioni, JC., Kudla, G. and Miska, EA., COMRADES determines in vivo RNA structures and interactions Nature Methods,
  • Huch Ortega, M., Aloia, L., Miska, E. and Brand, A., Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration Nature Cell Biology,
    Doi: 10.1038/s41556-019-0402-6
  • Matsushima, W., Brink, K., Schroeder, J., Miska, EA. and Gapp, K., Mature sperm small-RNA profile in the sparrow: implications for transgenerational effects of age on fitness. Environmental Epigenetics, v. 5
    Doi: http://doi.org/10.1093/eep/dvz007
  • Baudet, M., Zivraj, KH., Abreu-Goodger, C., Muldal, A., Armisen, J., Blenkiron, C., Goldstein, LD., Miska, E. and Holt, CE., miR-124 acts through coREST to control the onset of Sema3A sensitivity in navigating retinal growth cones Nature Neuroscience,
  • Gapp, K., Parada, G., Gross, F., Corcoba, A., Kaur, J., Grau, E., Hemberg, M., Bohacek, J. and Miska, E., Single paternal Dexamethasone challenge programs offspring metabolism and reveals multiple candidates in RNA-mediated inheritance iScience,
  • Burton, N., Riccio, C., Dallaire, A., Price, J., Jenkins, B., Koulman, A. and Miska, E., Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection Nature Communications,
    Doi: http://doi.org/10.1038/s41467-020-15555-8
  • Chandrasekaran, V., Desai, N., Burton, N., Yang, H., Jon, P., Miska, E. and Ramakrishnan, V., Visualising formation of the active site in the mitochondrial ribosome eLife,
    Doi: 10.7554/eLife.68806
  • Lewis, S., Ross, L., Bain, S., Pahita, E., Smith, S., Cordeux, R., Miska, E., Lenhard, B., Jiggins, F. and Sarkies, P., Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods PLoS Genetics,
  • Vernaz, G., Malinsky, M., Svardal, H., Du, M., Tyers, A., Santos, E., Durbin, R., Genner, M., Turner, G. and Miska, E., Mapping epigenetic divergence in the massive radiation of Lake Malawi cichlid fishes Nature Communications,
  • Dallaire, A., Manley, BF., Wilkens, M., Bista, I., Quan, C., Evangelisti, E., Bradshaw, CR., Ramakrishna, NB., Schornak, S., Butter, F., Paszkowski, U. and Miska, E., Transcriptional activity and epigenetic regulation of transposable elements in the symbiotic fungus Rhizopagus irregularis Genome Research,
  • Gapp, K., van Steenwyk, G., Germain, P-L., Matsushima, W., Rudolph, K., Manuella, F., Roszkowski, M., Vernaz, G., Ghosh, T., Pelczar, P., Mansuy, I. and Miska, E., Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal trauma Molecular Psychiatry,
  • Burton, N., Willis, A., Fisher, K., Braukmann, F., Price, J., Stevens, L., Baugh, LR., Reinke, A. and Miska, E., Intergenerational adaptations to stress are evolutionarily conserved, stress-specific, and have deleterious trade-offs eLife,
    Doi: 10.7554/eLife.73425
  • Miska, EA. and Ferguson-Smith, AC., Transgenerational inheritance: Models and mechanisms of non-DNA sequence-based inheritance. Science, v. 354
    Doi: 10.1126/science.aaf4945
  • Braukmann, F., Jordan, D., Jenkins, B., Koulman, A. and Miska, E., SID-2 negatively regulates development likely independent of nutritional dsRNA uptake RNA Biology,
  • Dias De Vasconcelos Almeida, M., Vernaz, G., Putman, A. and Miska, E., Taming transposable elements in vertebrates: from epigenetic silencing to domestication Trends in Genetics,
  • Ziv, O., Price, J., Shalamova, L., Kamenova, T., Goodfellow, I., Weber, F. and Miska, E., The short- and long-range RNA-RNA Interactome of SARS-CoV-2 Molecular Cell,
  • Navarro, IC., Tuorto, F., Jordan, D., Legrand, C., Price, J., Braukmann, F., Hendrick, A., Akay, A., Kotter, A., Helm, M., Lyko, F. and Miska, E., Translational adaptation to heat stress is mediated by 5-methylcytosine RNA modification in Caenorhabditis elegans The EMBO Journal,
  • Venkataraman, GG., Miska, EA. and Jordan, DJ., Processive and Distributive Non-Equilibrium Networks Discriminate in Alternate Limits Journal of Statistical Mechanics: Theory and Experiment,
  • Kranse, O., Beasley, H., Adams, S., Pires-daSilva, A., Bell, C., Lilley, C., Urwin, P., Bird, D., Miska, E., Smant, G., Gheysen, G., Jones, J., Viney, M., Abad, P., Maier, T., Baum, T., Siddique, S., Williamson, V., Akay, A. and Eves-Van Den Akker, S., Towards genetic modification of plant-parasitic nematodes: delivery of macromolecules to adults and expression of exogenous mRNA in second stage juveniles G3: Genes, Genomes, Genetics,
    Doi: 10.1093/g3journal/jkaa058
  • Ramakrishna, NB., Battistoni, G., Surani, A., Hannon, G. and Miska, E., Mouse Primordial Germ Cell-Like Cells Lack piRNAs Developmental Cell,
    Doi: 10.1016/j.devcel.2022.11.004
  • Braukmann, F., Jordan, D. and Miska, E., Artificial and natural RNA interactions between bacteria and $\textit{C. elegans}$ RNA Biology, v. 14
    Doi: http://doi.org/10.1080/15476286.2017.1297912
  • Matsushima, W., Herzog, VA., Neumann, T., Gapp, K., Zuber, J., Ameres, SL. and Miska, EA., Sequencing cell-type-specific transcriptomes with SLAM-ITseq. Nature Protocols,
    Doi: http://doi.org/10.1038/s41596-019-0179-x
  • Berkyurek, AC., Furlan, G., Lampersberger, L., Beltran, T., Weick, E-M., Nischwitz, E., Navarro, IC., Braukmann, F., Akay, A., Price, J., Butter, F., Sarkies, P. and Miska, E., The RNA Polymerase II subunit RPB-9 recruits Integrator to terminate C. elegans piRNA transcription The EMBO Journal,
  • Van Haute, L., Lee, S-Y., McCann, BJ., Powell, CA., Bansal, D., Vasiliauskaitė, L., Garone, C., Shin, S., Kim, J-S., Frye, M., Gleeson, JG., Miska, EA., Rhee, H-W. and Minczuk, M., NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs. Nucleic Acids Research,
    Doi: http://doi.org/10.1093/nar/gkz559
  • Lampersberger, L., Conte, F., Ghosh, S., Xiao, Y., Price, J., Jordan, D., Matus, DQ., Sarkies, P., Beli, P., Miska, EA. and Burton, NO., Loss of the E3 ubiquitin ligases UBR-5 or HECD-1 restores Caenorhabditis elegans development in the absence of SWI/SNF function. Proc Natl Acad Sci U S A, v. 120
    Doi: 10.1073/pnas.2217992120
  • Bista, I., Wood, JMD., Desvignes, T., McCarthy, SA., Matschiner, M., Ning, Z., Tracey, A., Torrance, J., Sims, Y., Chow, W., Smith, M., Oliver, K., Haggerty, L., Salzburger, W., Postlethwait, JH., Howe, K., Clark, MS., William Detrich, H., Christina Cheng, C-H., Miska, EA. and Durbin, R., Genomics of cold adaptations in the Antarctic notothenioid fish radiation Nature Communications, v. 14
    Doi: 10.1038/s41467-023-38567-6
  • tanguy, M., Veron, L., Stempor, P., Ahringer, J., Sarkies, P. and Miska, EA., An alternative STAT signaling pathway acts in viral immunity in Caenorhabditis elegans mBio,
  • Durbin, R., Miska, E. and McCarthy, S., Genomics of cold adaptations in the Antarctic notothenioid fish radiation Nature Communications,
  • Miska, EA., Le Pen, J., Kosalka, J., Kneuss, E., Di Domenico, T. and Rudolph, K., Terminal uridylytransferases target RNA viruses as part of the innate immune system in animals Nature Structural and Molecular Biology,
  • Internet publications

    2022

  • Bista, I., Wood, J., Desvignes, T., McCarthy, S., Matschiner, M., Ning, Z., Tracey, A., Torrance, J., Sims, Y., Chow, W., Smith, M., Oliver, K., Haggerty, L., Salzburger, W., Postlethwait, J., Howe, K., Clark, M., Detrich, W., Cheng, C-HC., Miska, E. and Durbin, R., 2022. Genomics of cold adaptations in the Antarctic notothenioid fish radiation
    Doi: 10.1101/2022.06.08.494096
  • 2021

  • Dallaire, A., Manley, BF., Wilkens, M., Bista, I., Quan, C., Evangelisti, E., Bradshaw, CR., Ramakrishna, NB., Schornack, S., Schornack, S., Butter, F., Paszkowski, U. and Miska, EA., 2021. Transcriptional activity and epigenetic regulation of transposable elements in the symbiotic fungus <i>Rhizophagus irregularis</i>
    Doi: 10.1101/2021.03.30.436303
  • 2020

  • Ziv, O., Price, J., Shalamova, L., Kamenova, T., Goodfellow, I., Weber, F. and Miska, E., 2020. The short- and long-range RNA-RNA Interactome of SARS-CoV-2
    Doi: 10.1101/2020.07.19.211110
  • Vernaz, G., Malinsky, M., Svardal, H., Du, M., Tyers, A., Santos, E., Durbin, R., Genner, M., Turner, G. and Miska, E., 2020. Mapping epigenetic divergence in the massive radiation of Lake Malawi cichlid fishes
    Doi: 10.1101/2020.11.24.383034
  • 2019

  • Svardal, H., Quah, FX., Malinsky, M., Ngatunga, B., Miska, E., Salzburger, W., Genner, M., Turner, G. and Durbin, R., 2019. Ancestral hybridisation facilitated species diversification in the Lake Malawi cichlid fish adaptive radiation
    Doi: 10.1101/738633
  • Matsushima, W., Brink, K., Schroeder, J., Miska, EA. and Gapp, K., 2019. Mature sperm small RNA profile in the sparrow: implications for transgenerational effects of age on fitness
    Doi: http://doi.org/10.1101/520759
  • Protasio, AV., Rawlinson, KA., Miska, EA., Berriman, M. and Rinaldi, G., 2019. Evidence for transposable element control by Argonautes in a parasitic flatworm lacking the piRNA pathway
    Doi: 10.1101/670372
  • Georgakopoulos-Soares, I., Parada, G., Wong, HY., Miska, E., Kwok, CK. and Hemberg, M., 2019. Alternative splicing modulation by G-quadruplexes
    Doi: 10.1101/700575
  • Braukmann, F., Jordan, D. and Miska, EA., 2019. A genetic pathway encoding double-stranded RNA transporters and interactors regulates growth and plasticity in<i>Caenorhabditis elegans</i>
    Doi: 10.1101/694414
  • 2018

  • Malinsky, M., Svardal, H., Tyers, A., Miska, E., Genner, M., Turner, G. and Durbin, R., 2018. Whole-genome sequences of Malawi cichlids reveal multiple radiations interconnected by gene flow
    Doi: http://doi.org/10.1038/s41559-018-0717-x
  • Akay, A., Jordan, D., Navarro, I., Wrzesinski, T., Ponting, C., Miska, E. and Haerty, W., 2018. Identification of functional long non-coding RNAs in C. elegans
    Doi: http://doi.org/10.1101/383919
  • Le Pen, J., Jiang, H., Di Domenico, T., Kneuss, E., Kosalka, J., Morgan, M., Much, C., Rudolph, K., Enright, A., O'Carroll, D., Wang, D. and Miska, E., 2018. Terminal uridylyltransferases target RNA viruses as part of the innate immune system in animals
    Doi: 10.1101/209114
  • Gapp, K., van Steenwyk, G., Germain, PL., Matsushima, W., Rudolph, KLM., Manuella, F., Roszkowski, M., Vernaz, G., Ghosh, T., Pelczar, P., Mansuy, IM. and Miska, EA., 2018. Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal trauma
    Doi: 10.1101/386037
  • 2017

  • Matsushima, W., Herzog, V., Neumann, T., Gapp, K., Zuber, J., Ameres, S. and Miska, E., 2017. SLAM-ITseq: Sequencing cell type-specific transcriptomes without cell sorting
    Doi: 10.1101/235093
  • Tanguy, M., Véron, L., Stempor, P., Ahringer, J., Sarkies, P. and Miska, E., 2017. An alternative STAT signaling pathway acts in antiviral immunity in <i>Caenorhabditis elegans</i>
    Doi: 10.1101/110940
  • Book chapters

    2021

  • Miska, EA. and Rechavi, O., 2021. Can brain activity transmit transgenerationally?
    Doi: http://doi.org/10.1016/bs.ctdb.2021.03.001
  • 2007

  • Alvarez Garcia, I. and Miska, EA., 2007. The microRNAs of C. elegans
    Doi: http://doi.org/10.1017/CBO9780511541766.004
  • Conference proceedings

    2019

  • Dallaire, A., Ramakrishna, N., Manley, B., Paszkowski, U. and Miska, E., 2019. Small regulatory RNAs and epigenetic control of Arbuscular Mycorrhizal Symbiosis MOLECULAR PLANT-MICROBE INTERACTIONS, v. 32
  • 2016

  • Fisher, B., Sandovici, I., Braukmann, F., Frederiksen, H., Constancia, M., Miska, E. and Acerini, C., 2016. Effects of Developmental Bisphenol A Exposure on Spermatozoal microRNA Expression HORMONE RESEARCH IN PAEDIATRICS, v. 86
  • 2015

  • Miska, E., 2015. Transgenerational epigenetic inheritance and RNAe FEBS JOURNAL, v. 282
  • 2010

  • Miska, E., 2010. The complex life of small RNA NEW BIOTECHNOLOGY, v. 27
    Doi: 10.1016/j.nbt.2010.01.304
  • 2008

  • Miska, EA., Lehrbach, NJ. and Das, P., 2008. Small RNAs in germline development and human cancer CELLULAR ONCOLOGY, v. 30
  • 2007

  • Miska, EA., 2007. Microrna expression profiles classify human cancers CYTOMETRY PART B-CLINICAL CYTOMETRY, v. 72B
  • 1999

  • Brehm, A., Miska, E., Reid, J., Bannister, A. and Kouzarides, T., 1999. The cell cycle-regulating transcription factors E2F-RB. Br J Cancer, v. 80 Suppl 1
  • Datasets
  • Puntambekar, S., Newhouse, R., San Miguel Navas, J., Chauhan, R., Willis, T., Wayland, MT., Urmania, Y., Vernaz, G., Miska, EA. and Prabakaran, S., Research Data Supporting "Rapid speciation of cichlids fishes may be explained by novel open reading frames"
  • Theses / dissertations

    2022

  • Riccio, C., 2022. Duplication is a prominent mechanism of recent gene birth in Caenorhabditis elegans
  • Clark, B., Elkin, J., Marconi, A., Turner, G., Smith, A., Joyce, D., Miska, E., Juntti, S. and Santos, E., 2022. <i>oca2</i> targeting using CRISPR/Cas9 in the Malawi cichlid <i>Astatotilapia calliptera</i>
    Doi: 10.1101/2022.01.01.474687
  • Ramakrishna, NB., Small Non-Coding RNAs in the Developing Human Germline
  • Matsushima, W., Analyses of RNA dynamics in Mus musculus
  • Medhi, R., Terminal uridyl transferases: TUT4/7-mediated RNA metabolism in cancer
  • Parada Gonzalez, GE., Computational analyses of non-canonical architectural and structural features associated with alternative splicing
  • Working papers

    2017

  • McMurchy, A., Stempor, P., Gaarenstroom, T., Wysolmerski, B., Dong, Y., Aussianikava, D., Appert, A., Huang, N., Kolasinska-Zwierz, P., Sapetschnig, A., Miska, E. and Ahringer, J., 2017. A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress
    Doi: 10.1101/112847