Anton Enright

University Assistant Professor and Group Leader, Department of Pathology

Anton Enright aims to detect, predict and describe the functions of genes, proteins and regulatory non-coding RNAs as well as their interactions in living organisms and their implications for disease. Learn more.

Research Areas

Computational Genomics

Non-coding RNAs and disease

Epitranscriptomics

Techniques

High performance computing

Bioinformatics

High-throughput genomics

Research Theme

Publications

Journal articles

2023

McGeoghan, F., Camera, E., Maiellaro, M., Menon, M., Huang, M., Dewan, P., Ziaj, S., Caley, MP., Donaldson, M., Enright, AJ. and O'Toole, EA., 2023. RNA sequencing and lipidomics uncovers novel pathomechanisms in recessive X-linked ichthyosis. Front Mol Biosci, v. 10
Doi: http://doi.org/10.3389/fmolb.2023.1176802

2022

Protasio, AV., Dongen, SV., Collins, J., Quintais, L., Ribeiro, DM., Sessler, F., Hunt, M., Rinaldi, G., Collins, JJ., Enright, AJ. and Berriman, M., 2022. Correction: MiR-277/4989 regulate transcriptional landscape during juvenile to adult transition in the parasitic helminth Schistosoma mansoni. PLoS Negl Trop Dis, v. 16
Doi: http://doi.org/10.1371/journal.pntd.0010521

Dumetz, F., Enright, AJ., Zhao, J., Kwok, CK. and Merrick, CJ., 2022. The in vivo RNA structurome of the malaria parasite Plasmodium falciparum, a protozoan with an A/U-rich transcriptome. PLoS One, v. 17
Doi: 10.1371/journal.pone.0270863

Shmeleva, EV., Gomez de Agüero, M., Wagner, J., Enright, AJ., Macpherson, AJ., Ferguson, BJ. and Smith, GL., 2022. Smallpox vaccination induces a substantial increase in commensal skin bacteria that promote pathology and influence the host response. PLoS Pathog, v. 18
Doi: 10.1371/journal.ppat.1009854

2021

Groves, I., Drane, ELA., Michalski, M., Monahan, J., Scarpini, C., Smith, S., Bussotti, G., Várnai, C., Schoenfelder, S., Fraser, P., Enright, A. and Coleman, N., 2021. Three-dimensional interactions between integrated HPV genomes and cellular chromatin dysregulate host gene expression in early cervical carcinogenesis
Doi: 10.1101/2021.02.03.429496

2020

López-Leal, R., Díaz-Viraqué, F., Catalán, RJ., Saquel, C., Enright, A., Iraola, G. and Court, FA., 2020. Schwann cell reprogramming into repair cells increases miRNA-21 expression in exosomes promoting axonal growth. J Cell Sci, v. 133
Doi: http://doi.org/10.1242/jcs.239004

Enjalbert, F., Dewan, P., Caley, MP., Jones, EM., Morse, MA., Kelsell, DP., Enright, AJ. and O'Toole, EA., 2020. 3D model of harlequin ichthyosis reveals inflammatory therapeutic targets. J Clin Invest, v. 130
Doi: http://doi.org/10.1172/JCI132987

Larrea, E., Fernandez-Mercado, M., Guerra-Assunção, JA., Wang, J., Goicoechea, I., Gaafar, A., Ceberio, I., Lobo, C., Okosun, J., Enright, AJ., Fitzgibbon, J. and Lawrie, CH., 2020. Identification of Recurrent Mutations in the microRNA-Binding Sites of B-Cell Lymphoma-Associated Genes in Follicular Lymphoma. Int J Mol Sci, v. 21
Doi: http://doi.org/10.3390/ijms21228795

2019

Morgan, M., Kabayama, Y., Much, C., Ivanova, I., Di Giacomo, M., Auchynnikava, T., Monahan, JM., Vitsios, DM., Vasiliauskaitė, L., Comazzetto, S., Rappsilber, J., Allshire, RC., Porse, BT., Enright, AJ. and O'Carroll, D., 2019. A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis. Cell Res, v. 29
Doi: http://doi.org/10.1038/s41422-018-0128-1

Nazarie, FW., Shih, B., Angus, T., Barnett, MW., Chen, S-H., Summers, KM., Klein, K., Faulkner, GJ., Saini, HK., Watson, M., Dongen, SV., Enright, AJ. and Freeman, TC., 2019. Visualization and analysis of RNA-Seq assembly graphs. Nucleic Acids Res, v. 47
Doi: http://doi.org/10.1093/nar/gkz599

Leger, A., Amaral, P., Pandolfini, L., Capitanchik, C., Capraro, F., Barbieri, I., Migliori, V., Luscombe, N., Enright, A., Tzelepis, K., Ule, J., Fitzgerald, T., Birney, E., Leonardi, T. and Kouzarides, T., 2019. RNA modifications detection by comparative Nanopore direct RNA sequencing
Doi: 10.1101/843136

Capalbo, L., Bassi, Z., Geymonat, M., Todesca, S., Copoiu, L., Enright, A., Callaini, G., Riparbelli, MG., Yu, L., Choudhary, J., Ferrero, E., Wheatley, S., Douglas, M., Mishima, M. and D’Avino, PP., 2019. The midbody interactome reveals new unexpected roles for PP1 phosphatases in cytokinesis
Doi: 10.1101/569459

2018

Bitetti, A., Mallory, AC., Golini, E., Carrieri, C., Carreño Gutiérrez, H., Perlas, E., Pérez-Rico, YA., Tocchini-Valentini, GP., Enright, AJ., Norton, WHJ., Mandillo, S., O'Carroll, D. and Shkumatava, A., 2018. MicroRNA degradation by a conserved target RNA regulates animal behavior. Nat Struct Mol Biol, v. 25
Doi: http://doi.org/10.1038/s41594-018-0032-x

Amaral, PP., Leonardi, T., Han, N., Viré, E., Gascoigne, DK., Arias-Carrasco, R., Büscher, M., Pandolfini, L., Zhang, A., Pluchino, S., Maracaja-Coutinho, V., Nakaya, HI., Hemberg, M., Shiekhattar, R., Enright, AJ. and Kouzarides, T., 2018. Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci. Genome Biology, v. 19
Doi: 10.1186/s13059-018-1405-5

Vasiliauskaitė, L., Berrens, RV., Ivanova, I., Carrieri, C., Reik, W., Enright, AJ. and O'Carroll, D., 2018. Defective germline reprogramming rewires the spermatogonial transcriptome. Nat Struct Mol Biol, v. 25
Doi: http://doi.org/10.1038/s41594-018-0058-0

Schor, IE., Bussotti, G., Maleš, M., Forneris, M., Viales, RR., Enright, AJ. and Furlong, EEM., 2018. Non-coding RNA Expression, Function, and Variation during Drosophila Embryogenesis. Curr Biol, v. 28
Doi: http://doi.org/10.1016/j.cub.2018.09.026

Nazarie, F., Shih, B., Angus, T., Barnett, M., Chen, S-H., Summers, K., Klein, K., Faulkner, G., Saini, H., Watson, M., Dongen, SV., Enright, A. and Freeman, T., 2018. Visualisation and analysis of RNA-Seq assembly graphs
Doi: 10.1101/409573

2017

White, RJ., Collins, JE., Sealy, IM., Wali, N., Dooley, CM., Digby, Z., Stemple, DL., Murphy, DN., Billis, K., Hourlier, T., Fullgrabe, A., Davis, MP., Enright, AJ. and Busch-Nentwich, EM., 2017. A high-resolution mRNA expression time course of embryonic development in zebrafish ELIFE, v. 6
Doi: http://doi.org/10.7554/eLife.30860.001

Protasio, AV., van Dongen, S., Collins, J., Quintais, L., Ribeiro, DM., Sessler, F., Hunt, M., Rinaldi, G., Collins, JJ., Enright, AJ. and Berriman, M., 2017. MiR-277/4989 regulate transcriptional landscape during juvenile to adult transition in the parasitic helminth Schistosoma mansoni PLoS neglected tropical diseases, v. 11
Doi: 10.1371/journal.pntd.0005559

Morgan, M., Much, C., Digiacomo, M., Azzi, C., Ivanova, I., Vitsios, DM., Pistolic, J., Collier, P., Moreira, PN., Benes, V., Enright, AJ. and O'Carroll, D., 2017. mRNA 3′ Uridylation and Poly(A) Tail Length Sculpt the Mammalian Maternal Transcriptome Nature, v. 72
Doi: http://doi.org/10.1097/OGX.0000000000000499

Wu, Q., Ferry, QRV., Baeumler, TA., Michaels, YS., Vitsios, DM., Habib, O., Arnold, R., Jiang, X., Maio, S., Steinkraus, BR., Tapia, M., Piazza, P., Xu, N., Holländer, GA., Milne, TA., Kim, J-S., Enright, AJ., Bassett, AR. and Fulga, TA., 2017. In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering. Nat Commun, v. 8
Doi: http://doi.org/10.1038/s41467-017-00686-2

Vasiliauskaitė, L., Vitsios, D., Berrens, RV., Carrieri, C., Reik, W., Enright, AJ. and O'Carroll, D., 2017. A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming. Nat Struct Mol Biol, v. 24
Doi: http://doi.org/10.1038/nsmb.3413

Davis, MP., Carrieri, C., Saini, HK., van Dongen, S., Leonardi, T., Bussotti, G., Monahan, JM., Auchynnikava, T., Bitetti, A., Rappsilber, J., Allshire, RC., Shkumatava, A., O'Carroll, D. and Enright, AJ., 2017. Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution. EMBO Rep, v. 18
Doi: http://doi.org/10.15252/embr.201744059

Iraci, N., Gaude, E., Leonardi, T., Costa, ASH., Cossetti, C., Peruzzotti-Jametti, L., Bernstock, JD., Saini, HK., Gelati, M., Vescovi, AL., Bastos, C., Faria, N., Occhipinti, LG., Enright, AJ., Frezza, C. and Pluchino, S., 2017. Extracellular vesicles are independent metabolic units with asparaginase activity Nature Chemical Biology,
Doi: http://doi.org/10.1038/nchembio.2422

Morgan, M., Much, C., DiGiacomo, M., Azzi, C., Ivanova, I., Vitsios, DM., Pistolic, J., Collier, P., Moreira, PN., Benes, V., Enright, AJ. and O'Carroll, D., 2017. mRNA 3' uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome. Nature, v. 548
Doi: http://doi.org/10.1038/nature23318

Vitsios, DM., Davis, MP., van Dongen, S. and Enright, AJ., 2017. Large-scale analysis of microRNA expression, epi-transcriptomic features and biogenesis. Nucleic Acids Res, v. 45
Doi: http://doi.org/10.1093/nar/gkw1031

Vitsios, DM., Kentepozidou, E., Quintais, L., Benito-Gutiérrez, E., van Dongen, S., Davis, MP. and Enright, AJ., 2017. Mirnovo: genome-free prediction of microRNAs from small RNA sequencing data and single-cells using decision forests. Nucleic Acids Res, v. 45
Doi: 10.1093/nar/gkx836

Ivanova, I., Much, C., Di Giacomo, M., Azzi, C., Morgan, M., Moreira, PN., Monahan, J., Carrieri, C., Enright, AJ. and O'Carroll, D., 2017. The RNA m6A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence. Mol Cell, v. 67
Doi: http://doi.org/10.1016/j.molcel.2017.08.003

Ranzani, M., Kemper, K., Michaut, M., Krijgsman, O., Aben, N., Iyer, V., Wong, K., Roumeliotis, T., Velasco-Herrera, MDC., Nsengimana, J., Turner, G., Thompson, N., Shahrabi, A., Sjoberg, M., Rashid, M., Speak, A., Grinkevich, V., Behan, F., Tamborero, D., Iorio, F., van Dongen, S., Bignell, G., Alsinet, C., Chen, S., Supper, E., Dutton-Regester, K., Pritchard, A., Wong, C., Enright, A., Newton-Bishop, J., McDermott, U., Hayward, N., Choudhary, J., Yusa, K., Wessels, L., Garnett, M., Peeper, D. and Adams, D., 2017. A screen for combination therapies inBRAF/NRASwild type melanoma identifies nilotinib plus MEK inhibitor as a synergistic combination
Doi: http://doi.org/10.1101/195354

Gutiérrez-Vázquez, C., Enright, AJ., Rodríguez-Galán, A., Pérez-García, A., Collier, P., Jones, MR., Benes, V., Mizgerd, JP., Mittelbrunn, M., Ramiro, AR. and Sánchez-Madrid, F., 2017. 3' Uridylation controls mature microRNA turnover during CD4 T-cell activation. RNA, v. 23
Doi: http://doi.org/10.1261/rna.060095.116

White, R., Collins, J., Sealy, I., Wali, N., Dooley, C., Digby, Z., Stemple, D., Murphy, D., Hourlier, T., Füllgrabe, A., Davis, M., Enright, A. and Busch-Nentwich, E., 2017. A high-resolution mRNA expression time course of embryonic development in zebrafish
Doi: 10.1101/107631

2016

Robertson, KA., Hsieh, WY., Forster, T., Blanc, M., Lu, H., Crick, PJ., Yutuc, E., Watterson, S., Martin, K., Griffiths, SJ., Enright, AJ., Yamamoto, M., Pradeepa, MM., Lennox, KA., Behlke, MA., Talbot, S., Haas, J., Dölken, L., Griffiths, WJ., Wang, Y., Angulo, A. and Ghazal, P., 2016. An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway. PLoS Biol, v. 14
Doi: 10.1371/journal.pbio.1002364

Vargel, Ö., Zhang, Y., Kosim, K., Ganter, K., Foehr, S., Mardenborough, Y., Shvartsman, M., Enright, AJ., Krijgsveld, J. and Lancrin, C., 2016. Activation of the TGFβ pathway impairs endothelial to haematopoietic transition. Sci Rep, v. 6
Doi: http://doi.org/10.1038/srep21518

Furió-Tarí, P., Tarazona, S., Gabaldón, T., Enright, AJ. and Conesa, A., 2016. spongeScan: A web for detecting microRNA binding elements in lncRNA sequences. Nucleic Acids Res, v. 44
Doi: http://doi.org/10.1093/nar/gkw443

Bussotti, G., Leonardi, T., Clark, MB., Mercer, TR., Crawford, J., Malquori, L., Notredame, C., Dinger, ME., Mattick, JS. and Enright, AJ., 2016. Improved definition of the mouse transcriptome via targeted RNA sequencing. Genome research, v. 26
Doi: http://doi.org/10.1101/gr.199760.115

Lewis, MA., Buniello, A., Hilton, JM., Zhu, F., Zhang, WI., Evans, S., van Dongen, S., Enright, AJ. and Steel, KP., 2016. Exploring regulatory networks of miR-96 in the developing inner ear. Sci Rep, v. 6
Doi: 10.1038/srep23363

2015

Pavlopoulos, GA., Malliarakis, D., Papanikolaou, N., Theodosiou, T., Enright, AJ. and Iliopoulos, I., 2015. Visualizing genome and systems biology: technologies, tools, implementation techniques and trends, past, present and future. Gigascience, v. 4
Doi: 10.1186/s13742-015-0077-2

Murray, MJ., Raby, KL., Saini, HK., Bailey, S., Wool, SV., Tunnacliffe, JM., Enright, AJ., Nicholson, JC. and Coleman, N., 2015. Solid tumors of childhood display specific serum microRNA profiles. Cancer Epidemiol Biomarkers Prev, v. 24
Doi: 10.1158/1055-9965.EPI-14-0669

Witte, S., Bradley, A., Enright, AJ. and Muljo, SA., 2015. High-density P300 enhancers control cell state transitions. BMC Genomics, v. 16
Doi: http://doi.org/10.1186/s12864-015-1905-6

Vitsios, DM. and Enright, AJ., 2015. Chimira: analysis of small RNA sequencing data and microRNA modifications. Bioinformatics, v. 31
Doi: http://doi.org/10.1093/bioinformatics/btv380

Clark, MB., Mercer, TR., Bussotti, G., Leonardi, T., Haynes, KR., Crawford, J., Brunck, ME., Cao, KA., Thomas, GP., Chen, WY., Taft, RJ., Nielsen, LK., Enright, AJ., Mattick, JS. and Dinger, ME., 2015. Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing. Nat Methods, v. 12
Doi: http://doi.org/10.1038/nmeth.3321

Murray, MJ., Raby, KL., Saini, HK., Bailey, S., Wool, SV., Tunnacliffe, JM., Enright, AJ., Nicholson, JC. and Coleman, N., 2015. Solid Tumors of Childhood Display Specific Serum microRNA Profiles CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, v. 24
Doi: 10.1158/1055-9965.EPI-14-0669

2014

Cossetti, C., Iraci, N., Mercer, TR., Leonardi, T., Alpi, E., Drago, D., Alfaro-Cervello, C., Saini, HK., Davis, MP., Schaeffer, J., Vega, B., Stefanini, M., Zhao, C., Muller, W., Garcia-Verdugo, J., Mathivanan, S., Bachi, A., Enright, AJ., Mattick, JS. and Pluchino, S., 2014. Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells Molecular Cell, v. 56
Doi: http://doi.org/10.1016/j.molcel.2014.11.009

Murray, MJ., Bailey, S., Raby, KL., Saini, HK., de Kock, L., Burke, GA., Foulkes, WD., Enright, AJ., Tischkowitz, M. and Coleman, N., 2014. Serum levels of mature microRNAs in DICER1-mutated pleuropulmonary blastoma VIRCHOWS ARCHIV, v. 465

Murray, MJ., Raby, KL., Saini, HK., Bailey, S., Wool, SV., Tunnacliffe, JM., Enright, AJ., Nicholson, JC. and Coleman, N., 2014. Solid tumours of childhood display specific serum microRNA profiles VIRCHOWS ARCHIV, v. 465

Wright, DW., Angus, T., Enright, AJ. and Freeman, TC., 2014. Visualisation of BioPAX Networks using BioLayout Express (3D). F1000Res, v. 3
Doi: 10.12688/f1000research.5499.1

Cossetti, C., Iraci, N., Mercer, TR., Leonardi, T., Alpi, E., Drago, D., Alfaro-Cervello, C., Saini, HK., Davis, MP., Schaeffer, J., Vega, B., Stefanini, M., Zhao, CJ., Muller, W., Garcia-Verdugo, JM., Mathivanan, S., Bachi, A., Enright, AJ., Mattick, JS. and Pluchino, S., 2014. Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells Molecular Cell, v. 56
Doi: http://doi.org/10.1016/j.molcel.2014.11.009

Camps, C., Saini, HK., Mole, DR., Choudhry, H., Reczko, M., Guerra-Assunção, JA., Tian, Y-M., Buffa, FM., Harris, AL., Hatzigeorgiou, AG., Enright, AJ. and Ragoussis, J., 2014. Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia. Mol Cancer, v. 13
Doi: http://doi.org/10.1186/1476-4598-13-28

Murray, MJ., Bailey, S., Raby, KL., Saini, HK., de Kock, L., Burke, GAA., Foulkes, WD., Enright, AJ., Coleman, N. and Tischkowitz, M., 2014. Serum levels of mature microRNAs in DICER1-mutated pleuropulmonary blastoma. Oncogenesis, v. 3
Doi: 10.1038/oncsis.2014.1

2013

Bussotti, G., Notredame, C. and Enright, AJ., 2013. Detecting and comparing non-coding RNAs in the high-throughput era. Int J Mol Sci, v. 14
Doi: 10.3390/ijms140815423

Davis, MPA., van Dongen, S., Abreu-Goodger, C., Bartonicek, N. and Enright, AJ., 2013. Kraken: a set of tools for quality control and analysis of high-throughput sequence data. Methods, v. 63
Doi: http://doi.org/10.1016/j.ymeth.2013.06.027

Di Giacomo, M., Comazzetto, S., Saini, H., De Fazio, S., Carrieri, C., Morgan, M., Vasiliauskaite, L., Benes, V., Enright, AJ. and O'Carroll, D., 2013. Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis. Mol Cell, v. 50
Doi: http://doi.org/10.1016/j.molcel.2013.04.026

Lupini, L., Bassi, C., Ferracin, M., Bartonicek, N., D'Abundo, L., Zagatti, B., Callegari, E., Musa, G., Moshiri, F., Gramantieri, L., Corrales, FJ., Enright, AJ., Sabbioni, S. and Negrini, M., 2013. miR-221 affects multiple cancer pathways by modulating the level of hundreds messenger RNAs. Front Genet, v. 4
Doi: http://doi.org/10.3389/fgene.2013.00064

Hanning, JE., Saini, HK., Murray, MJ., van Dongen, S., Davis, MPA., Barker, EM., Ward, DM., Scarpini, CG., Enright, AJ., Pett, MR. and Coleman, N., 2013. Lack of correlation between predicted and actual off-target effects of short-interfering RNAs targeting the human papillomavirus type 16 E7 oncogene. Br J Cancer, v. 108
Doi: 10.1038/bjc.2012.564

Clare, S., John, V., Walker, AW., Hill, JL., Abreu-Goodger, C., Hale, C., Goulding, D., Lawley, TD., Mastroeni, P., Frankel, G., Enright, AJ., Vigorito, E. and Dougan, G., 2013. Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice. Infect Immun, v. 81
Doi: 10.1128/IAI.00969-12

Howe, K., Clark, MD., Torroja, CF., Torrance, J., Berthelot, C., Muffato, M., Collins, JE., Humphray, S., McLaren, K., Matthews, L., McLaren, S., Sealy, I., Caccamo, M., Churcher, C., Scott, C., Barrett, JC., Koch, R., Rauch, G-J., White, S., Chow, W., Kilian, B., Quintais, LT., Guerra-Assunção, JA., Zhou, Y., Gu, Y., Yen, J., Vogel, J-H., Eyre, T., Redmond, S., Banerjee, R., Chi, J., Fu, B., Langley, E., Maguire, SF., Laird, GK., Lloyd, D., Kenyon, E., Donaldson, S., Sehra, H., Almeida-King, J., Loveland, J., Trevanion, S., Jones, M., Quail, M., Willey, D., Hunt, A., Burton, J., Sims, S., McLay, K., Plumb, B., Davis, J., Clee, C., Oliver, K., Clark, R., Riddle, C., Elliot, D., Threadgold, G., Harden, G., Ware, D., Begum, S., Mortimore, B., Kerry, G., Heath, P., Phillimore, B., Tracey, A., Corby, N., Dunn, M., Johnson, C., Wood, J., Clark, S., Pelan, S., Griffiths, G., Smith, M., Glithero, R., Howden, P., Barker, N., Lloyd, C., Stevens, C., Harley, J., Holt, K., Panagiotidis, G., Lovell, J., Beasley, H., Henderson, C., Gordon, D., Auger, K., Wright, D., Collins, J., Raisen, C., Dyer, L., Leung, K., Robertson, L., Ambridge, K., Leongamornlert, D., McGuire, S., Gilderthorp, R., Griffiths, C., Manthravadi, D., Nichol, S., Barker, G., Whitehead, S., Kay, M., Brown, J., Murnane, C., Gray, E., Humphries, M., Sycamore, N., Barker, D., Saunders, D., Wallis, J., Babbage, A., Hammond, S., Mashreghi-Mohammadi, M., Barr, L., Martin, S., Wray, P., Ellington, A., Matthews, N., Ellwood, M., Woodmansey, R., Clark, G., Cooper, JD., Tromans, A., Grafham, D., Skuce, C., Pandian, R., Andrews, R., Harrison, E., Kimberley, A., Garnett, J., Fosker, N., Hall, R., Garner, P., Kelly, D., Bird, C., Palmer, S., Gehring, I., Berger, A., Dooley, CM., Ersan-Ürün, Z., Eser, C., Geiger, H., Geisler, M., Karotki, L., Kirn, A., Konantz, J., Konantz, M., Oberländer, M., Rudolph-Geiger, S., Teucke, M., Lanz, C., Raddatz, G., Osoegawa, K., Zhu, B., Rapp, A., Widaa, S., Langford, C., Yang, F., Schuster, SC., Carter, NP., Harrow, J., Ning, Z., Herrero, J., Searle, SMJ., Enright, A., Geisler, R., Plasterk, RHA., Lee, C., Westerfield, M., de Jong, PJ., Zon, LI., Postlethwait, JH., Nüsslein-Volhard, C., Hubbard, TJP., Roest Crollius, H., Rogers, J. and Stemple, DL., 2013. The zebrafish reference genome sequence and its relationship to the human genome. Nature, v. 496
Doi: http://doi.org/10.1038/nature12111

Murray, MJ., Saini, HK., Siegler, CA., Hanning, JE., Barker, EM., van Dongen, S., Ward, DM., Raby, KL., Groves, IJ., Scarpini, CG., Pett, MR., Thornton, CM., Enright, AJ., Nicholson, JC., Coleman, N. and CCLG, , 2013. LIN28 Expression in malignant germ cell tumors downregulates let-7 and increases oncogene levels. Cancer Res, v. 73
Doi: 10.1158/0008-5472.CAN-12-2085

Hanning, JE., Saini, HK., Murray, MJ., Caffarel, MM., van Dongen, S., Ward, D., Barker, EM., Scarpini, CG., Groves, IJ., Stanley, MA., Enright, AJ., Pett, MR. and Coleman, N., 2013. Depletion of HPV16 early genes induces autophagy and senescence in a cervical carcinogenesis model, regardless of viral physical state. J Pathol, v. 231
Doi: 10.1002/path.4244

2012

van Dongen, S. and Enright, AJ., 2012. Metric distances derived from cosine similarity and Pearson and Spearman correlations

Lu, D., Davis, MPA., Abreu-Goodger, C., Wang, W., Campos, LS., Siede, J., Vigorito, E., Skarnes, WC., Dunham, I., Enright, AJ. and Liu, P., 2012. MiR-25 regulates Wwp2 and Fbxw7 and promotes reprogramming of mouse fibroblast cells to iPSCs. PLoS One, v. 7
Doi: http://doi.org/10.1371/journal.pone.0040938

Selcuklu, SD., Donoghue, MTA., Rehmet, K., de Souza Gomes, M., Fort, A., Kovvuru, P., Muniyappa, MK., Kerin, MJ., Enright, AJ. and Spillane, C., 2012. MicroRNA-9 inhibition of cell proliferation and identification of novel miR-9 targets by transcriptome profiling in breast cancer cells. J Biol Chem, v. 287
Doi: http://doi.org/10.1074/jbc.M111.335943

Hu, M., Ayub, Q., Guerra-Assunção, JA., Long, Q., Ning, Z., Huang, N., Romero, IG., Mamanova, L., Akan, P., Liu, X., Coffey, AJ., Turner, DJ., Swerdlow, H., Burton, J., Quail, MA., Conrad, DF., Enright, AJ., Tyler-Smith, C. and Xue, Y., 2012. Exploration of signals of positive selection derived from genotype-based human genome scans using re-sequencing data. Hum Genet, v. 131
Doi: http://doi.org/10.1007/s00439-011-1111-9

Guerra-Assunção, JA. and Enright, AJ., 2012. Large-scale analysis of microRNA evolution. BMC Genomics, v. 13
Doi: http://doi.org/10.1186/1471-2164-13-218

Gurha, P., Abreu-Goodger, C., Wang, T., Ramirez, MO., Drumond, AL., van Dongen, S., Chen, Y., Bartonicek, N., Enright, AJ., Lee, B., Kelm, RJ., Reddy, AK., Taffet, GE., Bradley, A., Wehrens, XH., Entman, ML. and Rodriguez, A., 2012. Targeted deletion of microRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction. Circulation, v. 125
Doi: http://doi.org/10.1161/CIRCULATIONAHA.111.044354

Parts, L., Hedman, ÅK., Keildson, S., Knights, AJ., Abreu-Goodger, C., van de Bunt, M., Guerra-Assunção, JA., Bartonicek, N., van Dongen, S., Mägi, R., Nisbet, J., Barrett, A., Rantalainen, M., Nica, AC., Quail, MA., Small, KS., Glass, D., Enright, AJ., Winn, J., MuTHER Consortium, , Deloukas, P., Dermitzakis, ET., McCarthy, MI., Spector, TD., Durbin, R. and Lindgren, CM., 2012. Extent, causes, and consequences of small RNA expression variation in human adipose tissue. PLoS Genet, v. 8
Doi: 10.1371/journal.pgen.1002704

Davis, MPA., Abreu-Goodger, C., van Dongen, S., Lu, D., Tate, PH., Bartonicek, N., Kutter, C., Liu, P., Skarnes, WC., Enright, AJ. and Dunham, I., 2012. Large-scale identification of microRNA targets in murine Dgcr8-deficient embryonic stem cell lines. PLoS One, v. 7
Doi: http://doi.org/10.1371/journal.pone.0041762

2011

Puri, V., Goyal, A., Sankaranarayanan, R., Enright, AJ. and Vaidya, T., 2011. Evolutionary and functional insights into Leishmania META1: evidence for lateral gene transfer and a role for META1 in secretion. BMC Evol Biol, v. 11
Doi: http://doi.org/10.1186/1471-2148-11-334

Tripathi, R., Saini, HK., Rad, R., Abreu-Goodger, C., van Dongen, S. and Enright, AJ., 2011. Messenger RNA and microRNA profiling during early mouse EB formation. Gene Expr Patterns, v. 11
Doi: 10.1016/j.gep.2011.03.004

De Fazio, S., Bartonicek, N., Di Giacomo, M., Abreu-Goodger, C., Sankar, A., Funaya, C., Antony, C., Moreira, PN., Enright, AJ. and O'Carroll, D., 2011. The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature, v. 480
Doi: http://doi.org/10.1038/nature10547

Mayoral, RJ., Deho, L., Rusca, N., Bartonicek, N., Saini, HK., Enright, AJ. and Monticelli, S., 2011. MiR-221 influences effector functions and actin cytoskeleton in mast cells. PLoS One, v. 6
Doi: http://doi.org/10.1371/journal.pone.0026133

Bateman, A., Agrawal, S., Birney, E., Bruford, EA., Bujnicki, JM., Cochrane, G., Cole, JR., Dinger, ME., Enright, AJ., Gardner, PP., Gautheret, D., Griffiths-Jones, S., Harrow, J., Herrero, J., Holmes, IH., Huang, H., Kelly, KA., Kersey, P., Kozomara, A., Lowe, TM., Marz, M., Moxon, S., Pruitt, KD., Samuelsson, T., Stadler, PF., Vilella, AJ., Vogel, J., Williams, KP., Wright, MW. and Zwieb, C., 2011. RNAcentral: A vision for an international database of RNA sequences RNA, v. 17
Doi: http://doi.org/10.1261/rna.2750811

2010

Rasmussen, KD., Simmini, S., Abreu-Goodger, C., Bartonicek, N., Di Giacomo, M., Bilbao-Cortes, D., Horos, R., Von Lindern, M., Enright, AJ. and O'Carroll, D., 2010. The miR-144/451 locus is required for erythroid homeostasis. J Exp Med, v. 207
Doi: http://doi.org/10.1084/jem.20100458

Bartonicek, N. and Enright, AJ., 2010. SylArray: a web server for automated detection of miRNA effects from expression data. Bioinformatics, v. 26
Doi: http://doi.org/10.1093/bioinformatics/btq545

Santhakumar, D., Forster, T., Laqtom, NN., Fragkoudis, R., Dickinson, P., Abreu-Goodger, C., Manakov, SA., Choudhury, NR., Griffiths, SJ., Vermeulen, A., Enright, AJ., Dutia, B., Kohl, A., Ghazal, P. and Buck, AH., 2010. Combined agonist-antagonist genome-wide functional screening identifies broadly active antiviral microRNAs. Proc Natl Acad Sci U S A, v. 107
Doi: http://doi.org/10.1073/pnas.1008861107

Guerra-Assunção, JA. and Enright, AJ., 2010. MapMi: automated mapping of microRNA loci. BMC Bioinformatics, v. 11
Doi: http://doi.org/10.1186/1471-2105-11-133

Sudbery, I., Enright, AJ., Fraser, AG. and Dunham, I., 2010. Systematic analysis of off-target effects in an RNAi screen reveals microRNAs affecting sensitivity to TRAIL-induced apoptosis. BMC Genomics, v. 11
Doi: http://doi.org/10.1186/1471-2164-11-175

Piipari, M., Down, TA., Saini, H., Enright, A. and Hubbard, TJP., 2010. iMotifs: an integrated sequence motif visualization and analysis environment. Bioinformatics, v. 26
Doi: http://doi.org/10.1093/bioinformatics/btq026

Fabani, MM., Abreu-Goodger, C., Williams, D., Lyons, PA., Torres, AG., Smith, KGC., Enright, AJ., Gait, MJ. and Vigorito, E., 2010. Efficient inhibition of miR-155 function in vivo by peptide nucleic acids. Nucleic Acids Res, v. 38
Doi: http://doi.org/10.1093/nar/gkq160

Murray, MJ., Saini, HK., van Dongen, S., Palmer, RD., Muralidhar, B., Pett, MR., Piipari, M., Thornton, CM., Nicholson, JC., Enright, AJ. and Coleman, N., 2010. The two most common histological subtypes of malignant germ cell tumour are distinguished by global microRNA profiles, associated with differential transcription factor expression. Mol Cancer, v. 9
Doi: 10.1186/1476-4598-9-290

Palmer, RD., Murray, MJ., Saini, HK., van Dongen, S., Abreu-Goodger, C., Muralidhar, B., Pett, MR., Thornton, CM., Nicholson, JC., Enright, AJ., Coleman, N. and Children's Cancer and Leukaemia Group, , 2010. Malignant germ cell tumors display common microRNA profiles resulting in global changes in expression of messenger RNA targets. Cancer Res, v. 70
Doi: 10.1158/0008-5472.CAN-09-3301

2009

Theocharidis, A., van Dongen, S., Enright, AJ. and Freeman, TC., 2009. Network visualization and analysis of gene expression data using BioLayout Express(3D). Nat Protoc, v. 4
Doi: http://doi.org/10.1038/nprot.2009.177

Lewis, MA., Quint, E., Glazier, AM., Fuchs, H., De Angelis, MH., Langford, C., van Dongen, S., Abreu-Goodger, C., Piipari, M., Redshaw, N., Dalmay, T., Moreno-Pelayo, MA., Enright, AJ. and Steel, KP., 2009. An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice. Nat Genet, v. 41
Doi: http://doi.org/10.1038/ng.369

Manakov, SA., Grant, SGN. and Enright, AJ., 2009. Reciprocal regulation of microRNA and mRNA profiles in neuronal development and synapse formation. BMC Genomics, v. 10
Doi: http://doi.org/10.1186/1471-2164-10-419

Mishima, Y., Abreu-Goodger, C., Staton, AA., Stahlhut, C., Shou, C., Cheng, C., Gerstein, M., Enright, AJ. and Giraldez, AJ., 2009. Zebrafish miR-1 and miR-133 shape muscle gene expression and regulate sarcomeric actin organization. Genes Dev, v. 23
Doi: http://doi.org/10.1101/gad.1760209

2008

van Dongen, S., Abreu-Goodger, C. and Enright, AJ., 2008. Detecting microRNA binding and siRNA off-target effects from expression data. Nat Methods, v. 5
Doi: http://doi.org/10.1038/nmeth.1267

Saini, HK., Enright, AJ. and Griffiths-Jones, S., 2008. Annotation of mammalian primary microRNAs. BMC Genomics, v. 9
Doi: http://doi.org/10.1186/1471-2164-9-564

Skrabanek, L., Saini, HK., Bader, GD. and Enright, AJ., 2008. Computational prediction of protein-protein interactions. Mol Biotechnol, v. 38
Doi: http://doi.org/10.1007/s12033-007-0069-2

Griffiths-Jones, S., Saini, HK., van Dongen, S. and Enright, AJ., 2008. miRBase: tools for microRNA genomics. Nucleic Acids Res, v. 36
Doi: http://doi.org/10.1093/nar/gkm952

Saini, HK., Enright, AJ. and Griffiths-Jones, S., 2008. Annotation of mammalian primary microRNAs BMC Genomics, v. 9
Doi: 10.1186/1471-2164-9-564

Raza, S., Robertson, KA., Lacaze, PA., Page, D., Enright, AJ., Ghazal, P. and Freeman, TC., 2008. A logic-based diagram of signalling pathways central to macrophage activation. BMC Syst Biol, v. 2
Doi: http://doi.org/10.1186/1752-0509-2-36

2007

O'Carroll, D., Mecklenbrauker, I., Das, PP., Santana, A., Koenig, U., Enright, AJ., Miska, EA. and Tarakhovsky, A., 2007. A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway. Genes Dev, v. 21
Doi: 10.1101/gad.1565607

Rodriguez, A., Vigorito, E., Clare, S., Warren, MV., Couttet, P., Soond, DR., van Dongen, S., Grocock, RJ., Das, PP., Miska, EA., Vetrie, D., Okkenhaug, K., Enright, AJ., Dougan, G., Turner, M. and Bradley, A., 2007. Requirement of bic/microRNA-155 for normal immune function. Science, v. 316
Doi: 10.1126/science.1139253

Vigorito, E., Perks, KL., Abreu-Goodger, C., Bunting, S., Xiang, Z., Kohlhaas, S., Das, PP., Miska, EA., Rodriguez, A., Bradley, A., Smith, KGC., Rada, C., Enright, AJ., Toellner, K-M., Maclennan, ICM. and Turner, M., 2007. microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity, v. 27
Doi: 10.1016/j.immuni.2007.10.009

Kamburov, A., Goldovsky, L., Freilich, S., Kapazoglou, A., Kunin, V., Enright, AJ., Tsaftaris, A. and Ouzounis, CA., 2007. Denoising inferred functional association networks obtained by gene fusion analysis. BMC Genomics, v. 8
Doi: http://doi.org/10.1186/1471-2164-8-460

Mazière, P. and Enright, AJ., 2007. Prediction of microRNA targets. Drug Discov Today, v. 12
Doi: http://doi.org/10.1016/j.drudis.2007.04.002

Saini, HK., Griffiths-Jones, S. and Enright, AJ., 2007. Genomic analysis of human microRNA transcripts. Proc Natl Acad Sci U S A, v. 104
Doi: http://doi.org/10.1073/pnas.0703890104

Freeman, TC., Goldovsky, L., Brosch, M., van Dongen, S., Mazière, P., Grocock, RJ., Freilich, S., Thornton, J. and Enright, AJ., 2007. Construction, visualisation, and clustering of transcription networks from microarray expression data. PLoS Comput Biol, v. 3
Doi: http://doi.org/10.1371/journal.pcbi.0030206

2006

Giraldez, AJ., Mishima, Y., Rihel, J., Grocock, RJ., Van Dongen, S., Inoue, K., Enright, AJ. and Schier, AF., 2006. Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science, v. 312
Doi: http://doi.org/10.1126/science.1122689

Griffiths-Jones, S., Grocock, RJ., van Dongen, S., Bateman, A. and Enright, AJ., 2006. miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res, v. 34
Doi: http://doi.org/10.1093/nar/gkj112

Blow, MJ., Grocock, RJ., van Dongen, S., Enright, AJ., Dicks, E., Futreal, PA., Wooster, R. and Stratton, MR., 2006. RNA editing of human microRNAs. Genome Biol, v. 7
Doi: http://doi.org/10.1186/gb-2006-7-4-r27

2005

Goldovsky, L., Cases, I., Enright, AJ. and Ouzounis, CA., 2005. BioLayout(Java): versatile network visualisation of structural and functional relationships. Appl Bioinformatics, v. 4
Doi: http://doi.org/10.2165/00822942-200504010-00009

John, B., Enright, AJ., Aravin, A., Tuschl, T., Sander, C. and Marks, DS., 2005. Human microRNA targets (vol 2, pg 1862, 2005) PLOS BIOLOGY, v. 3
Doi: 10.1371/journal.pbio.0030264

Goldovsky, L., Janssen, P., Ahrén, D., Audit, B., Cases, I., Darzentas, N., Enright, AJ., López-Bigas, N., Peregrin-Alvarez, JM., Smith, M., Tsoka, S., Kunin, V. and Ouzounis, CA., 2005. CoGenT++: an extensive and extensible data environment for computational genomics. Bioinformatics, v. 21
Doi: http://doi.org/10.1093/bioinformatics/bti579

Smith, M., Kunin, V., Goldovsky, L., Enright, AJ. and Ouzounis, CA., 2005. MagicMatch--cross-referencing sequence identifiers across databases. Bioinformatics, v. 21
Doi: http://doi.org/10.1093/bioinformatics/bti548

John, B., Enright, AJ., Aravin, A., Tuschl, T., Sander, C. and Marks, DS., 2005. Erratum: Human microRNA targets (PLoS Biology 2:11 DOI: 10.1371/journal.pbio.0020363) PLoS Biology, v. 3
Doi: http://doi.org/10.1371/journal.pbio.0030264

Giraldez, AJ., Cinalli, RM., Glasner, ME., Enright, AJ., Thomson, JM., Baskerville, S., Hammond, SM., Bartel, DP. and Schier, AF., 2005. MicroRNAs regulate brain morphogenesis in zebrafish. Science, v. 308
Doi: http://doi.org/10.1126/science.1109020

2004

Bader, GD. and Enright, AJ., 2004. Intermolecular interactions and biological pathways

Pereira-Leal, JB., Enright, AJ. and Ouzounis, CA., 2004. Detection of functional modules from protein interaction networks. Proteins, v. 54
Doi: http://doi.org/10.1002/prot.10505

Pfeffer, S., Zavolan, M., Grässer, FA., Chien, M., Russo, JJ., Ju, J., John, B., Enright, AJ., Marks, D., Sander, C. and Tuschl, T., 2004. Identification of virus-encoded microRNAs. Science, v. 304
Doi: http://doi.org/10.1126/science.1096781

John, B., Enright, AJ., Aravin, A., Tuschl, T., Sander, C. and Marks, DS., 2004. Human MicroRNA targets. PLoS Biol, v. 2
Doi: http://doi.org/10.1371/journal.pbio.0020363

2003

Iliopoulos, I., Enright, AJ., Poullet, P. and Ouzounis, CA., 2003. Mapping functional associations in the entire genome of Drosophila melanogaster using fusion analysis. Comp Funct Genomics, v. 4
Doi: http://doi.org/10.1002/cfg.287

Enright, AJ., John, B., Gaul, U., Tuschl, T., Sander, C. and Marks, DS., 2003. MicroRNA targets in Drosophila. Genome Biol, v. 5
Doi: http://doi.org/10.1186/gb-2003-5-1-r1

Enright, A., John, B., Gaul, U., Tuschl, T., Sander, C. and Marks, D., 2003. Genome Biology, v. 4
Doi: 10.1186/gb-2003-4-11-p8

Ouzounis, CA., Coulson, RMR., Enright, AJ., Kunin, V. and Pereira-Leal, JB., 2003. Classification schemes for protein structure and function. Nat Rev Genet, v. 4
Doi: http://doi.org/10.1038/nrg1113

Janssen, P., Enright, AJ., Audit, B., Cases, I., Goldovsky, L., Harte, N., Kunin, V. and Ouzounis, CA., 2003. COmplete GENome Tracking (COGENT): a flexible data environment for computational genomics. Bioinformatics, v. 19
Doi: http://doi.org/10.1093/bioinformatics/btg161

Enright, AJ., Kunin, V. and Ouzounis, CA., 2003. Protein families and TRIBES in genome sequence space. Nucleic Acids Res, v. 31
Doi: http://doi.org/10.1093/nar/gkg495

Kunin, V., Cases, I., Enright, AJ., de Lorenzo, V. and Ouzounis, CA., 2003. Myriads of protein families, and still counting. Genome Biol, v. 4
Doi: http://doi.org/10.1186/gb-2003-4-2-401

Iliopoulos, I., Tsoka, S., Andrade, MA., Enright, AJ., Carroll, M., Poullet, P., Promponas, V., Liakopoulos, T., Palaios, G., Pasquier, C., Hamodrakas, S., Tamames, J., Yagnik, AT., Tramontano, A., Devos, D., Blaschke, C., Valencia, A., Brett, D., Martin, D., Leroy, C., Rigoutsos, I., Sander, C. and Ouzounis, CA., 2003. Evaluation of annotation strategies using an entire genome sequence. Bioinformatics, v. 19
Doi: http://doi.org/10.1093/bioinformatics/btg077

2002

Enright, AJ., 2002. Computational analysis of protein function within complete genomes

Enright, AJ., Van Dongen, S. and Ouzounis, CA., 2002. An efficient algorithm for large-scale detection of protein families. Nucleic Acids Res, v. 30
Doi: http://doi.org/10.1093/nar/30.7.1575

2001

Boucher, L., Ouzounis, CA., Enright, AJ. and Blencowe, BJ., 2001. A genome-wide survey of RS domain proteins. RNA, v. 7

Iliopoulos, I., Enright, AJ. and Ouzounis, CA., 2001. Textquest: document clustering of Medline abstracts for concept discovery in molecular biology. Pac Symp Biocomput,
Doi: http://doi.org/10.1142/9789814447362_0038

Enright, AJ. and Ouzounis, CA., 2001. BioLayout--an automatic graph layout algorithm for similarity visualization. Bioinformatics, v. 17
Doi: http://doi.org/10.1093/bioinformatics/17.9.853

Coulson, RM., Enright, AJ. and Ouzounis, CA., 2001. Transcription-associated protein families are primarily taxon-specific. Bioinformatics, v. 17
Doi: http://doi.org/10.1093/bioinformatics/17.1.95

Enright, AJ. and Ouzounis, CA., 2001. Functional associations of proteins in entire genomes by means of exhaustive detection of gene fusions. Genome Biol, v. 2
Doi: http://doi.org/10.1186/gb-2001-2-9-research0034

2000

McLysaght, A., Enright, AJ., Skrabanek, L. and Wolfe, KH., 2000. Estimation of synteny conservation and genome compaction between pufferfish (Fugu) and human. Yeast, v. 17
Doi: http://doi.org/10.1002/(SICI)1097-0061(200004)17:1<22::AID-YEA5>3.0.CO;2-S

Promponas, VJ., Enright, AJ., Tsoka, S., Kreil, DP., Leroy, C., Hamodrakas, S., Sander, C. and Ouzounis, CA., 2000. CAST: an iterative algorithm for the complexity analysis of sequence tracts. Complexity analysis of sequence tracts. Bioinformatics, v. 16
Doi: http://doi.org/10.1093/bioinformatics/16.10.915

Enright, AJ. and Ouzounis, CA., 2000. GeneRAGE: a robust algorithm for sequence clustering and domain detection. Bioinformatics, v. 16
Doi: http://doi.org/10.1093/bioinformatics/16.5.451

1999

Enright, AJ., Iliopoulos, I., Kyrpides, NC. and Ouzounis, CA., 1999. Protein interaction maps for complete genomes based on gene fusion events. Nature, v. 402
Doi: http://doi.org/10.1038/47056

Groves, IJ., Drane, ELA., Michalski, M., Monahan, JM., Scarpini, CG., Smith, SP., Bussotti, G., Várnai, C., Schoenfelder, S., Fraser, P., Enright, AJ. and Coleman, N., Short- and long-range cis interactions between integrated HPV genomes and cellular chromatin dysregulate host gene expression in early cervical carcinogenesis. PLoS Pathogens, v. 17
Doi: http://doi.org/10.1371/journal.ppat.1009875

Kouzarides, T., Pandolfini, L., Amaral, P., Capitanchik, C., Capraro, F., Migliori, V., Miano, V., Toolan-Kerr, P., Sideri, T., Enright, A., Tzelepis, K., van Werven, F., Luscombe, N., Barbieri, I., Ule, J., Fitzgerald, T., Birney, E. and Leonardi, T., RNA modifications detection by comparative Nanopore direct RNA sequencing Nature Communications,

Murray, M., Small non-coding RNA sequencing reveals global dysregulation of piwi-interacting RNA (piRNA) expression in gonadal malignant germ cell tumours. Andrology,

D'Avino, P. and Halcrow, E., Midbody proteins display distinct temporal dynamics during cytokinesis Cells,

Manakov, SA., Morton, A., Enright, AJ. and Grant, SGN., A Neuronal Transcriptome Response Involving Stress Pathways is Buffered by Neuronal microRNAs. Frontiers in Neuroscience, v. 6
Doi: http://doi.org/10.3389/fnins.2012.00156

Miska, EA., Le Pen, J., Kosalka, J., Kneuss, E., Di Domenico, T. and Rudolph, K., Terminal uridylytransferases target RNA viruses as part of the innate immune system in animals Nature Structural and Molecular Biology,

D'Avino, P., The midbody interactome reveals new unexpected roles for PP1 phosphatases in cytokinesis Nature Communications,

Amaral, P., Leonardi, T., Han, N., Viré, E., Gascoigne, D., Arias-Carrasco, R., Büscher, M., Zhang, A., Pluchino, S., Maracaja-Coutinho, V., Nakaya, H., Hemberg, M., Shiekhattar, R., Enright, A. and Kouzarides, T., Genomic positional conservation identifies topological anchor point (tap)RNAs linked to developmental loci Genome Biology, v. 19
Doi: 10.1186/s13059-018-1405-5

Internet publications

2018

Le Pen, J., Jiang, H., Di Domenico, T., Kneuss, E., Kosalka, J., Morgan, M., Much, C., Rudolph, K., Enright, A., O'Carroll, D., Wang, D. and Miska, E., 2018. Terminal uridylyltransferases target RNA viruses as part of the innate immune system in animals
Doi: 10.1101/209114

2016

Amaral, P., Leonardi, T., Han, N., Viré, E., Gascoigne, D., Arias-Carrasco, R., Büscher, M., Zhang, A., Pluchino, S., Maracaja-Coutinho, V., Nakaya, H., Hemberg, M., Shiekhattar, R., Enright, A. and Kouzarides, T., 2016. Genomic positional conservation identifies topological anchor point (tap)RNAs linked to developmental loci
Doi: 10.1101/051052

Book chapters

2014

van Dongen, S. and Enright, AJ., 2014. Detecting microRNA signatures using gene expression analysis
Doi: http://doi.org/10.1007/978-3-642-30574-0_9

2007

Enright, AJ. and Griffiths-Jones, S., 2007. miRBase: A database of microRNA sequences, targets and nomenclature
Doi: http://doi.org/10.1017/CBO9780511541766.014

Conference proceedings

2020

Kang, ASW. and Enright, AJ., 2020. Locating patterns in Nanopore currents using time-warped signal representation of consensus nucleotides for demultiplexing and motif detection. Annu Int Conf IEEE Eng Med Biol Soc, v. 2020
Doi: http://doi.org/10.1109/EMBC44109.2020.9176358

2014

Leonardi, T., Iraci, N., Enright, AJ. and Pluchino, S., 2014. Characterisation of microRNA promoters in the murine genome FEBS JOURNAL, v. 281

Iraci, N., Leonardi, T., Enright, AJ. and Pluchino, S., 2014. Mechanisms of mobile ncRNAs in neural stem/precursor cells FEBS JOURNAL, v. 281

Iraci, N., Cossetti, C., Mercer, T., Leonardi, T., Alpi, E., Drago, D., Alfaro-cervello, C., Saini, H., Davis, M., Schaeffer, J., Muller, W., Manuel Garcia-verdugo, J., Mathivanan, S., Bachi, A., Enright, A., Mattick, J. and Pluchino, S., 2014. Extracellular vesicles from neural stem cells transfer the IFN-gamma/IFNGR1 complex to activate Stat1-dependent signalling in target cells JOURNAL OF NEUROIMMUNOLOGY, v. 275
Doi: 10.1016/j.jneuroim.2014.08.513

2013

Malouf, C., Bartonicek, N., Bacon, W., Kapeni, C., Enright, A. and Ottersbach, K., 2013. DECIPHERING THE ROLE OF MICRORNAS IN EARLY STAGES OF HAEMATOPOIESIS EXPERIMENTAL HEMATOLOGY, v. 41
Doi: 10.1016/j.exphem.2013.05.151

2012

Burrows, J., Saini, HK., Murray, MJ., van Dongen, S., Davis, M., Barker, EM., Enright, AJ., Pett, MR. and Coleman, N., 2012. There is no correlation between the predicted and actual off-target effects of siRNAs targeting the human papillomavirus type 16 E7 oncogene JOURNAL OF PATHOLOGY, v. 226

Murray, M., Saini, HK., Siegler, CA., Burrows, JE., Barker, EM., van Dongen, S., Pett, MR., Thornton, CM., Enright, AJ., Nicholson, JC. and Coleman, NC., 2012. Let-7 Down-regulation Links Over-expression of LIN28 and MYCN in Malignant Germ Cell Tumours JOURNAL OF PATHOLOGY, v. 226

2010

Matthew, MJ., Saini, HK., Van Dongen, S., Abreu-Goodger, C., Palmer, RD., Muralidhar, B., Pett, MR., Nicholson, JC., Enright, AJ. and Coleman, N., 2010. Malignant germ cell tumors display common microRNA profiles resulting in global changes in expression of mRNA targets CANCER RESEARCH, v. 70
Doi: http://doi.org/10.1158/1538-7445.AM10-3424

2008

Enright, AJ., 2008. Analysis of microRNA function through computation and experiment IMMUNOLOGY, v. 125

Anton Enright

University Assistant Professor and Group Leader, Department of Pathology

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