Professor of Structural Biology, Department of Biochemistry
Ernest Laue studies the way chromatin structure controls gene expression, and studies the structure and function of protein complexes involved in chromatin remodelling. In particular, the group focuses on the Nucleosome Remodelling and Deacetylase (NuRD) complex, which plays a key role in controlling the differentiation of embryonic stem (ES) cells and the reprogramming of adult cells to a pluripotent state. Learn more
Research AreasGenome architecture
Chromosome/chromatin structure
Enhancer function
Gene regulation
Early development
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TechniquesSingle molecule tracking
Super-resolution imaging
Single cell Hi-C
Computational biology
Structural biology
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Research Theme
