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Homepage
Welcome to the Laue Research Group website. Our group carries out structural studies of proteins and complexes that are important in cellular control. Our principal tool is Nuclear Magnetic Resonance (NMR) spectroscopy, but we also use X-ray crystallography and mass spectrometry, as well as biochemical and molecular biological methods, to solve structural problems. Our projects are supported by the BBSRC, the CR-UK, the European Union and the Wellcome Trust. In 1997, the group moved into the New Building of the Department of Biochemistry and 1998 saw the installation in our New Building of four new or upgraded Bruker NMR machines: two 500 MHz, one 600 MHz and one 800 MHz. These form a Departmental NMR Facility funded by the EPSRC and the BBSRC. We are working on three main projects and potential students are welcome to contact me about them: Chromatin mediated transcriptional repression Structure studies of protein kinases and inhibitor design Structural studies of membrane proteins Our other main interest is in NMR method development. |
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