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Jobs and studentships

4 Year PhD Studentship - Virology

From Jobs at the University of Cambridge. Published on Jan 28, 2015.

The Department of Pathology is offering a PhD Studentship commencing October 2015 and invites applications from UK and EU nationals**. Graduate students play a pivotal role in the continuing success of research in Cambridge and gaining a studentship in Cambridge is an excellent opportunity to start a research career in an environment committed to training outstanding research scientists of the future.

The project available is: Microenvironment Regulation of Human Papillomavirus Gene Expression and Disease supervised by Dr John Doorbar, http://www.path.cam.ac.uk/research/investigators/doorbar/research.html

Human Papillomaviruses are the primary cause of cervical and anal cancers, as well as around 50% of oropharyngeal cancers. Although the development of HPV-associated cancers is thought to involve the de-regulation of viral gene expression, the mechanisms that bring this about during neoplastic progression are unclear. The project will build on our observation that normal changes in the cellular microenvironment have a dramatic effect on viral mRNA processing and gene expression, and that these changes are linked to changes in viral copy number. The work will examine the mechanisms that underlie these changes and how such changes regulate disease severity.

Full details of the project and how to apply are available from the following link: http://www.path.cam.ac.uk/graduate/prospective-graduate-students/doorbar.html

Specific enquiries, and requests for more details of the project, can be made to John Doorbar at jd121@cam.ac.uk

Fixed-term: The funds for this post are available for 4 years and are joint funded by the MRC and the Department of Pathology.

**Research Council UK studentships are available to UK nationals and EU students who meet the UK residency requirements. Further information about eligibility for Research Council US funding can be found at the following website: http://www.mrc.ac.uk/skills-careers/studentships/studentship-guidance/student-eligibility-requirements/. Applications from ineligible candidates will not be considered.

The deadline for applications is Wednesday 11 February 2015. Applications received after this time will not be considered.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05236 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate - The Behavioural Ecology Group (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 28, 2015.

This position, based in central Cambridge at the Department of Zoology, University of Cambridge, is available for up to 28 months with a start date of 1 July 2015 to work with Prof Rebecca Kilner and her team. The project is funded by a European Research Council grant and will investigate whether parental care can drive evolutionary change.

Website nicrophorus.zoo.cam.ac.uk

Duties will include: Running a large-scale selection experiment Running or supervising complementary experiments in the lab or field Assisting in monitoring of beetle numbers at local field sites Collection and analysis of microsatellite data (or similar) Data collection, analysis and interpretation Preparation of manuscripts for publication

KNOWLEDGE, SKILLS AND EXPERIENCE FOR THE ROLE

Essential: A PhD in evolutionary ecology or behavioural ecology or entomology or closely related subjects Background knowledge (e.g. from degree course) of research methods and theory in behavioural ecology and evolutionary biology Ability to organise time, plan ahead and to work effectively independently. Good data handling and data analysis skills. Good communication skills (written and oral). Ability to work in a team and strong inter-personal skills.

Desirable: Some post-doctoral experience Any relevant laboratory experience, particularly in carrying out selection experiments or experimental evolution Experience in collecting and analysing microsatellite data (or similar) Experience of fieldwork with insects. Background knowledge (e.g. from degree course) of entomology or microbiology Interest in natural history. Some experience of managing others.

Deadline: 5pm Thursday 5 March 2015

Interview date: during week beginning 23 March 2015

Fixed-term: The funds for this post are available for up to 28 months.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PF05243 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Senior Building Services Technician

From Jobs at the University of Cambridge. Published on Jan 27, 2015.

Due to an internal promotion an opportunity has arisen for a versatile senior equipment/building services technician to compliment the existing team. The role holder will assist in the preventative maintenance/repair of our highly serviced building and electrical testing and fault finding of laboratory equipment.

The successful applicant must:- -Have a flexible approach to his/her workload to balance the needs of the research and work efficiently within a team environment -Be trained in an appropriate mechanical or electrical trade with experience working in building/maintenance services (or similar discipline) and laboratory research environment. -Be knowledgeable about associated regulations and legislation to comply with relevant Health & Safety legislation. -Experience with laboratory equipment is desirable. -Good communication skills, both verbal and written, and the ability to use computers are important.

Limited funding: The funds for this post are available for 18 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PR05233 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Senior Clinical Training Scholarship in Anaesthesia

From Jobs at the University of Cambridge. Published on Jan 27, 2015.

UNIVERSITY OF CAMBRIDGE DEPARTMENT OF VETERINARY MEDICINE THE QUEEN'S VETERINARY SCHOOL HOSPITAL

Start Date 3 August 2015

Scholarship award: £21,390.00 in year one.

The Scholarship is for one year in the first instance, renewable for periods of one year up to a total of three years.

The Scholarship provides an outstanding opportunity to receive specialist training in all aspects of veterinary anaesthesia. You will be required to register for a post-graduate qualification by enrolling onto the European Diploma in Veterinary Anaesthesia and Analgesia.

You will receive core training in all aspects of academic and clinical anaesthesia, pain management and peri-operative medicine (including critical care) in both small and large animals at the Queen's Veterinary School Hospital. You will also be required to undertake and publish a research project, and participate in the small-group teaching of veterinary students. The training programme is approved by the European College of Veterinary Anaesthesia and Analgesia.

You must be a Member of the Royal College of Veterinary Surgeons, or hold a veterinary degree qualifying you for membership. Membership will be required prior to commencing the Scholarship. A minimum of twelve months experience in a rotating internship or at least two years' experience in general practice is essential.

Informal discussion: contact Dr Jackie Brearley, jcb78@cam.ac.uk or Matthew McMillan mwm32@cam.ac.uk

Closing date: 8 March 2015

Interview date: 24 March 2015

Application form (SCTS1) and information pack about the Scholarship: download from link below.

Completed application form, curriculum vitae, covering letter: email vetmed@hermes.cam.ac.uk by closing date.

Please quote reference PP05229 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate/Senior Research Associate (Bioinformatician/Computational Biologist)

From Jobs at the University of Cambridge. Published on Jan 26, 2015.

Applications are invited for a Post-doctoral Research Associate or Senior Research Associate to investigate the regulation of chromatin, genome organisation, and gene expression in C. elegans through the analysis of high throughput sequencing data and other genome-wide data types. The successful applicant will work collaboratively within a lively research laboratory (http://www.gurdon.cam.ac.uk/~ahringerlab). A sound understanding of molecular biology and expertise in computational approaches for analysis of genome-wide information derived from high-throughput sequencing is essential. This should include an understanding of statistics and its application to large data sets. Applicants should have a PhD in a relevant subject.

Limited funding: The funds for this post are available until 30 September 2018 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made to Dr Julie Ahringer (ja219@cam.ac.uk).

Please quote reference PR05221 on your application and in any correspondence about this vacancy. The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Research Associate in Plant Biology (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 26, 2015.

The Department of Plant Sciences is searching for a highly motivated researcher to work in the lab of Prof Alex Webb. His lab have formed an interdisciplinary team to understand the function of the Poly(ADP-ribose) polymerases (PARPs) in stress tolerance of Arabidopsis. Data from our laboratories and others demonstrate that reduced PARP activity can increase stress tolerance. We aim to identify the mechanism(s) by which PARPs regulate stress tolerance. We also will study the sirtuins (SRTs), another class of NAD consuming enzymes that have close regulatory links with the PARPs and also Poly(ADP-ribose) glycohydrolase 1(PARG1) as this counters PARP activity.

PARPs add Poly(ADP-ribose) polymers to both DNA and proteins. The SRTs can act as deacetylases and are targets for the PARPs and thus the activity of these two enzymes are interwoven. PARGs remove Poly(ADPribose). Such is the complexity of these interactions, only a comprehensive and system wide analysis will reveal the mechanism by which PARPs regulate stress tolerance.

Our approach will be to investigate the consequence of PARPs, SRTs or PARG1 loss-of-function lines and perform molecular, phenotypic and mechanistic analyses. Molecular studies will comprise identification of the regions of DNA bound by the PARPs, SRTs and PARG1 and transcriptomic analysis in loss-of-function lines. Bioinformatic analyses of the data will identify direct targets and biological pathways under the control of the PARPs, SRTs and PARG1.

Phenotypic analysis in loss-of-function lines will determine the role of members of the PARPs, SRT and PARG gene families in stress tolerance and circadian regulation. The goal is to identify gene targets for crop improvement.

Mechanistic insight in to the mode of action of the NAD-consuming enzymes will be provided by analysis of the regulation of the HSP70 promoter, which is marker for chromatin regulation, in loss-of-function lines and analysis metabolic profiling of loss-of-function plants, with particular focus on NAD.

The applicant must possess a PhD in plant biology and a strong track record in plant biology research. The applicant must have experience of Arabidopsis molecular genetics, including RNA analysis, making transgenic lines and handling transgenic Arabidopsis plants. Experience of analysis of Arabidopsis mutants is essential. Experience of analysis of stress signalling and circadian rhythms in Arabidopsis is desirable.

Fixed-term: The funds for this post are available until 2 November 2017 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should provide a CV, the filename of which should be "CV-followed by your name", including contact details of two or more referees, and a covering letter addressing the selection criteria.

For further information contact Prof Alex Webb (aarw2@cam.ac.uk)

Please quote reference PD05220 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

J.C.T.S Small Animal Studies x 6

From Jobs at the University of Cambridge. Published on Jan 26, 2015.

UNIVERSITY OF CAMBRIDGE

DEPARTMENT OF VETERINARY MEDICINE

JUNIOR CLINICAL TRAINING SCHOLARSHIP SMALL ANIMAL STUDIES (6 SCHOLARSHIPS)

Scholarship award: £14,700 per annum

4 Scholarships to start on 1 July 2015

2 Scholarships to start on 2 November 2015

Fixed-term: 1 years.

Applications are invited for this one year post-graduate training programme based in the Queen's Veterinary School Small Animal Hospital. The scholarship is designed to provide a broad but intensive learning experience that acts to prepare individuals for Senior Clinical Training Programmes and potential specialisation. However, the scholarship will also benefit graduates seeking advanced training and experience prior to beginning practice. Scholars will rotate through a variety of small animal disciplines including Soft Tissue Surgery, Orthopaedics, Internal Medicine, Oncology, Neurology, Diagnostic Imaging, Anaesthesia and Clinical Pathology and will be an integral part of the out of hours care of animals within the hospital especially within the intensive care unit. Candidates must be Members of the Royal College of Veterinary Surgeons and should have experience of small animal general practice in the UK. New graduates may be considered. Informal enquiries: contact Matthew McMillan (programme supervisor) via email at mwm32@cam.ac.uk.

The deadline for applications is 1st March 2015.

Interviews will be held on 19th March 2015

An application form (JCTS1) and information pack can be downloaded from the link below.

Please send a completed application form, curriculum vitae, and covering letter by email to vetmed@hermes.cam.ac.uk clearly stating which Scholarship you are applying for (1 July or 1 November)

Please quote reference PP05225 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Post-doctoral Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 23, 2015.

A postdoctoral research associate position is available to work in the laboratory of Dr Tony Jackson based in the University of Cambridge, Department of Biochemistry, Tennis Court Road, Central Cambridge. The post is funded by the British Heart Foundation for up to three years. The project will study the sodium channel ß3-subunit, its role in sodium channel assembly and cardiac arrhythmias.

We are looking for an experienced ion channel electrophysiologist, ideally with expertise in single channel patch-clamp, general cell and molecular biological methods and a willingness to use primary animal tissues.

Candidates should have a PhD or the equivalent in a relevant science.

The work is a collaborative project between Dr A.P. Jackson and Prof. C-L. Huang (Dept. Physiology, Development and Neuroscience) and Dr A.J. Thompson (Dept. Pharmacology). It builds on recent evidence that the ß3-subunit can cross-link the heart-specific sodium channel Nav 1.5 and may help stabilise sodium channels on the plasma membranes of cardiomyocytes (see: Namadurai et al., Open Biol. 2015 5:140192. DOI: 10.1098/rsob.140192). The importance of this clustering will be investigated using cell biological and electrophysiological approaches, in primary cells derived from wild-type and ß3-knockout mice (see: Hakim, P et al., Acta. Physiol. 2010, 198, 47-59).

Fixed-term: The funds for this post are available for up to three years.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For all enquires please contact the Biochemistry Personnel - personnel@bioc.cam.ac.uk

Please quote reference PH05214 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Research Associate (Imaging filopodia)

From Jobs at the University of Cambridge. Published on Jan 23, 2015.

The Gallop laboratory seeks to understand the molecular mechanisms underlying the formation of distinct types of actin structure at different times and places in cells. We are a lively and interdisciplinary team that uses biochemistry, single molecule biophysics, superresolution and in vivo imaging.

A position will become available in June 2014 to use timelapse and super-resolution microscopy to measure the kinetics of protein recruitment and molecular architecture of cytoskeletal regulators in filopodia in vivo in Drosophila and/or Xenopus. The position involves collaborating within the group to generate new knock-in animals expressing fluorescently-tagged actin regulatory proteins using the CRISPR/Cas9 method, and visualising expression, localisation and actin dynamics by using high temporal and spatial resolution microscopy.

The successful applicant will have, or soon expect to receive, a PhD and previous experience in either Drosophila genetics or Xenopus developmental biology and take pride in acquiring beautiful and meaningful microscopy images. A first author paper in an international journal and experience in neuronal systems is a particular advantage. We are a multi-disciplinary team so the ability to communicate well with a variety of colleagues is important.

Limited funding: The funds for this post are available for 18 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries to Jenny Gallop j.gallop@gurdon.cam.ac.uk are welcomed, with formal application using the online University system

Please quote reference PR05211 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 22, 2015.

Applications are invited for a Naked Mole-Rat Initiative funded Postdoctoral Research Associate position in the laboratory of Dr Ewan St. John Smith at the Department of Pharmacology, University of Cambridge. We are looking for a motivated and innovative scientist to carry out research on a project focusing on the cellular and molecular basis of central chemoreceptor function in the naked mole-rat: more specifically, how carbon dioxide modulates circuits involved in respiratory function and fear. Dr Smith's lab uses a combination of electrophysiology, fluorescent imaging, immunohistochemistry and molecular biology to determine the key players in central chemoreception.

The role holder will be based in Central Cambridge. The key duties and responsibilities will include but not be limited to: developing research objectives and conducting the research project, writing up research work for presentation and publication, continually updating knowledge and understanding in the above field, translating knowledge of advances in the subject area into research activity, managing own research and administrative activities, assisting in the preparation of proposals and applications to external bodies (e.g. for funding and contractual purposes), communicating material of a specialist or highly technical nature.

Applicants should have, or expect to obtain shortly, a PhD in neuroscience or a related discipline. Successful candidates will be expected to have demonstrable experience in one or more of the following areas: patch-clamp electrophysiology, brain slice/neuronal culture methodology, neuroanatomy and live-cell imaging methods. You must be a careful and methodical worker, paying attention to accuracy and ready to take responsibility individually as well as part of a team. You should be self-motivated and able to organise, perform and analyse experiments with minimal instruction.

The funds for this post are available for 12 months in the first instance with effect from 1st April 2015 (a later start date is negotiable). The starting salary will be £28,695 pa. Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) and a security check. Whether the outcome is satisfactory will be determined by the University.

Informal enquiries about the position should be made to Dr Ewan St. John Smith (es336@cam.ac.uk).

The Department holds an Athena SWAN bronze award, demonstrating a commitment to provide equal opportunities and to advance the representation of women in science subjects. We welcome applications from all qualified candidates irrespective of gender but, as women are currently under-represented at this level in our department, we strongly encourage applications from female candidates. Appointment will be based on merit alone.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The online application is to include your personal details, names and addresses of referees, as well as your CV, research publications list and cover letter. For enquiries about the online application process please contact Ms Anna Osipova at recruitment@phar.cam.ac.uk.

Applications will be assessed as and when they are submitted and interviews will take place up to 10th March 2015.

Please quote reference PL05202 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Marie Curie ESR in Human Vision and Learning

From Jobs at the University of Cambridge. Published on Jan 19, 2015.

An early stage researcher position is available to work on visual perception and learning at the Adaptive Brain Lab (http://www.abg.psychol.cam.ac.uk). The project forms part of the ABC (http://www.adaptivebrain.eu) and PRISM network (www.prism-network.eu) that aims to uncover how the brain learns to represent objects and make optimal perceptual decisions. We aim to shed light on how we perceive 3D shapes, and learn to assign them into meaningful categories. The successful applicant will combine behavioural paradigms, with state-of-the-art brain imaging and computational modelling. They will receive multi-disciplinary research training at the interface between psychology, neuroscience, computer science, engineering and industrial design.

If desired, they will be able to apply for the Ph.D. programme in Cambridge. Applicants should have a Masters and/or First Degree, together with a strong academic track record, in a relevant area (e.g., Psychology, Neuroscience, Mathematics, Engineering, Computer Science, Physics). They must satisfy the eligibility requirements that apply to all Marie Curie Early Stage Researchers: they cannot be in possession of a PhD qualification, and should not have resided in the UK for more than 12 months before appointment. Please note this does not preclude residents of the UK (which includes UK/EU nationals and those with settlement or permanent residence in the UK) from applying for this position provided you meet these requirements.

The salary will comprise of a living allowance of €45,714 per annum and a mobility allowance of either €10,105.20 per annum or €14,436 per annum depending on individual family circumstances. Please note that the amounts stated are subject to employer deductions.

Informal enquiries should be directed to Professor Zoe Kourtzi (zk240@cam.ac.uk) or Dr Andrew Welchman (aew69@cam.ac.uk).

Further details may be downloaded below.

Fixed-term: The funds for this post are available for up to 20 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

If you do not hear from us within 4 weeks of the closing date please assume your application has been unsuccessful.

Please quote reference PJ05113 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

4-Year Targeted BBSRC DTP PhD Studentship

From Jobs at the University of Cambridge. Published on Jan 16, 2015.

The Department of Pathology is offering a PhD Studentship commencing October 2015 and invites applications from UK and EU nationals. Graduate students play a pivotal role in the continuing success of research in Cambridge and gaining a studentship in Cambridge is an excellent opportunity to start a research career in an environment committed to training outstanding research scientists of the future.

The project available is: Small GTPase signalling networks and subversion by pathogenic bacteria, supervised by Dr Daniel Humphreys, http://www.path.cam.ac.uk/research/investigators/humphreys/research.html

Small GTPases are master regulators of mammalian signalling networks regulating membrane trafficking and the actin cytoskeleton. Given their importance it is not surprising that a central paradigm in bacterial pathogenicity is small GTPase manipulation by pathogen-encoded virulence effectors that are injected into the host cell where they facilitate infection (e.g. Salmonella, Shigella, E.coli). The PhD project will use interdisciplinary approaches to unravel new small GTPase biology and discover how pathogens hijack the signalling mechanisms to cause disease. This is especially important given the health threat posed to humans and food chain animals by bacterial pathogens that continue to develop multidrug resistance. Understanding the basis of disease will not only illuminate fundamental biology but also has the potential to identify new therapeutic targets and augment our anti-infectives arsenal.

Specific enquiries, and requests for more details of the project, can be made to Daniel Humphreys at dh309@cam.ac.uk

Fixed-term: The funds for this post are available for 4 years.

Funding notes 4-year targeted BBSRC DTP PhD studentship within the theme of World-Class Underpinning Bioscience, including two rotational projects and a 12-week professional internship (PIPS). The studentship will cover a stipend at the standard Research Council rate (£13,863 per annum for 2014-2015), research costs and tuition fees at the UK/EU rate, and is available for UK and EU students who meet the UK residency requirements. http://bbsrcdtp.lifesci.cam.ac.uk/prospective

The deadline for applications is Sunday 15 February 2015. Applications received after this time will not be considered.

Full details of the project and how to apply are available from the following link:
http://www.path.cam.ac.uk/graduate/prospective-graduate-students/humphreys.html

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05150 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Horticultural Facility Manager

From Jobs at the University of Cambridge. Published on Jan 16, 2015.

Applications are invited for the position of Horticultural Facility Manager at The Sainsbury Laboratory, a basic research Institute within the University of Cambridge which focuses on plant developmental biology and computational modelling of plant development. When full, the Institute will have some 120 researchers and around 30 support staff.

As part of the Support Services team, the role-holder will report directly to the Facilities Manager and supervise two other team members, to keep the £4 million plant growth facility properly supported and operational. The research Horticultural Facility comprises of six glasshouse areas and forty-five growth chambers. The importance of maintaining good horticultural practice within the facility is paramount to the Institute's success, and so the day to day activities of the role-holder are essential to the research activities of the Institute.

The successful candidate must have at least a HND in Horticulture (or equivalent), substantial professional horticultural experience and PA1 and PA6 pesticide handling certificates.

Good observation and problem solving skills are essential, as well as knowledge of glasshouse environments and local and statutory Health and Safety requirements. Previous experience of growing plants under experimental conditions in a research environment would be advantageous.

The role holder will have a service orientated approach and excellent communication / interpersonal skills. A key requirement for the role is the ability to build positive working relationships with colleagues at all levels in research, support and administration. A flexible approach to work is also essential, including providing support and assistance to other members of the Support Services team. A license for forklift operation would be desirable.

The Further Information document for this post can be found on the Job Opportunities page or at http://www.slcu.cam.ac.uk/ along with information about the Sainsbury Laboratory.

Interviews are likely to take place during the week commencing 16 February 2015.

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within three weeks of the closing date, please consider your application as unsuccessful on this occasion.

Fixed-term: The funds for this post are available until 31 December 2016 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please also send a copy of your CV and a covering letter to: enquiries@slcu.cam.ac.uk

Please quote reference PT05162 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Domestic Assistants (Part Time)

From Jobs at the University of Cambridge. Published on Jan 14, 2015.

The Department of Pathology has two part-time, early morning, positions available for Domestic Assistants based at its site in central Cambridge with responsibilities for cleaning, portering and general housekeeping. Duties will include cleaning offices, laboratories, meeting rooms, toilets, canteen, lavatories and other communal areas. We can offer up to 15 hours a week for each position, Monday to Friday.

The post is managed through the Department's Facilities Office. A Domestic Services Supervisor co-ordinates the day-to-day activities of each Assistant. The Department is split across two sites, and on occasions the post holder will be required to provide cover at its other site in Addenbrooke's Hospital.

Experience of cleaning and an NVQ 1 or 2 in Cleaning Methods would be helpful, although full training will be given. Good communication skills are essential, along with the ability to follow both written and verbal instructions and to understand user and safety instructions regarding the use of chemicals and laboratory hazards. Due to the nature of the work, you will need to have a good level of physical fitness.

A welcoming manner, reliability, professionalism and a high level of attention to detail are also required.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a security check.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05107 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Clinical Skills Centre Facilitator (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 14, 2015.

University of Cambridge Department of Veterinary Medicine West Cambridge Site

Limit of Tenure: Three years in the first instance

The Department has just opened a brand new purpose-built Clinical Skills Centre (CSC) for the teaching and learning of a wide range of practical clinical skills to 200 veterinary students, e.g. catheter placement, reading of X rays, suturing, use of anaesthetic machines, rectal examination of equines and bovines, etc.

The resources in the CSC are used for practical skills teaching sessions led by academic staff as a complement to didactic and rotation teaching and learning, in order to reinforce techniques and good practice. The CSC also provides a resource for students to reinforce their own practical skills learning on an open access basis

This role reports to the Clinical Skills Centre Co-ordinator, who is the academic member of staff responsible for the CEC and for co-ordinating clinical skills strategy. The CSC is a recent innovation and there will be substantial ongoing work in developing Standard Operating Procedures and other management systems, and in equipping the CSC so that it can be used to its full potential.

The role will co-ordinate and manage the use of equipment, resources and time in the Clinical Skills Centre, will assist in the development of standard operating procedures; will support and facilitate clinical skills teaching and engage in the development of clinical skills teaching in the Clinical Skills Centre and elsewhere in the Department as required; and will manage a small consumables budget.

You must be a veterinary nurse registered with the Royal College of Veterinary Surgeons.

The following are essential:

  • Good IT skills.
  • Experience in the training of veterinary nurses or veterinary students is desirable.
  • Experience in using and having responsibility for care and maintenance of range of equipment commonly used in veterinary practice.
  • Excellent verbal and written communication skills in order to prepare and maintain documentation to a high standard and to communicate with academic and nursing colleagues and with veterinary students.
  • Significant post-registration nursing experience.
  • Experience of referral standard veterinary medical and surgical techniques.
  • Excellent level of practical skills in order to pass these on to students.
  • Excellent organisational skills.
  • Ability to organise own time and work.
  • Ability to address skills learning in a creative and innovative manner.

Closing date for applications: 8th February 2015

Interview date: 24th February 2015

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Department website: www.vet.cam.ac.uk

Further information: click on link below

Informal enquiries: Dr Jackie Brearley, jcb78@cam.ac.uk

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PP05137 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant - Bioinformatician (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 14, 2015.

Fixed-term: The funds for this post are available until 30 June 2017 in the first instance.

The Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute provides outstanding scientists with the opportunity and resources to undertake ground-breaking research into the fundamental properties of mammalian stem cells.

A new post has become available to support the growing computational biology community within the Cambridge Stem Cell Institute. The post holder will form part of a team of bioinformaticians dedicated to the application of modern bioinformatics techniques to stem cell research. The post holder will interact with bench scientists across the Cambridge stem cell community and the SCI IT service team. The projects aim to understand the molecular mechanisms regulating stem cell fate decisions at multiple layers.

The vacant post is at the Research Assistant level and the post holder will have a key role in managing the Bioinformatics infrastructure of the Stem Cell Institute. Candidates are expected to have a strong background in bioinformatics or computer science.

The ideal candidate will have experiences in analysis and interpretation of next-generation sequencing data and a good working knowledge of LINUX, such as using or managing job schedulers and resource management in a cluster environment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Sunday 15th February 2015.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Informal enquiries are also welcome via email: cscrjobs@cscr.cam.ac.uk.

Interviews will be held on the 26th or 27th February 2015. If you have not been invited for interview by 24th February 2015 , you have not been successful on this occasion.

Please quote reference PS04969 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Support Service Technician

From Jobs at the University of Cambridge. Published on Jan 14, 2015.

Based in Central Cambridge, you will enjoy working as part of a small friendly Bio-facility team. The Support Service maintains the essential provision of clean cages, drinking water bottles and materials to the animal technicians for the daily animal husbandry requirements.

After initial training you will be able to operate simple machinery, including dismantling and reassembling equipment for washing and sterilisation. You will be responsible for the in-house cleaning and some basic husbandry procedures. You will also be involved in the collection and delivery of stores, maintaining stocks and disposal of waste.

You should have a good general education and have ideally worked with or cared for animals. Previous experience would be beneficial but not essential as training will be provided.

The post is available immediately and subject to the satisfactory completion of a 3 month probationary period.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a security check.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Sunday 22nd February 2015.

Interviews will be held on the Monday 2nd March 2015. If you have not been invited for interview by 26th February 2015 , you have not been successful on this occasion.

Please quote reference PS05112 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

PhD Studentship (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 13, 2015.

PhD Studentship Department of Biochemistry, University of Cambridge

Single Cell Analysis in Microfluidic Droplets

A graduate studentship leading to the award of a PhD is available from 1 October 2015 (or later) to work at Cambridge University in the Biochemistry Department with Dr. F. Hollfelder (http://www.bioc.cam.ac.uk/hollfelder).

Single-cell studies promise to resolve ensemble measurements to give insight on cellular heterogeneity. Moving beyond averaging of populations this experimental approach provides more meaningful insight into the intrinsic cellular processes and the cellular responses to outside influences. We will study single cells compartmentalized in microfluidic droplets, thousands of cells can be studied by optical and transcriptomic analysis to identify interesting phenotypic characteristics, as a prelude to decipher molecular mechanisms, e.g. of cell diversification. The project will involve collaboration with Dr. Kevin Chalut (at the Stem Cell Institute - http://www.stemcells.cam.ac.uk/researchers/principal-investigators/kevin-chalut) and Dr. Sarah Teichmann (at the Department of Physics and the Euopean Bioinformatics Institute Single Cell Genomics Centre - http://www.ebi.ac.uk/~saraht/).

Applicants should have a first or upper second class degree in biochemistry, biotechnology, chemistry or a related, relevant subject. Specific skills in cell and molecular biology or, alternatively, microengineering techniques, microfluidics, soft lithography and applied physics are advantages.

This project is fully funded by the BBSRC for up to 48 months. Studentships are only available to citizens of the EU or the European Economic Area. To qualify for the full rate of the studentship UK residency requirements must be met (see e.g.

http://www.mrc.ac.uk/Fundingopportunities/Applicanthandbook/Studentships/Eligibility/index.htm#P17968 or http://www.bbsrc.ac.uk/web/FILES/Guidelines/studentshipeligibility.pdf).

The full stipend will be paid at RCUK rates for the 4 year duration of the award.

Fixed-term: The funds for this post are available for 4 years in the first instance.

Applications should contain a description of your research interests (e.g. as part of the cover letter) and your detailed CV (with exam marks and all relevant practical experience). Please also include the names and email-addresses of at least two referees, who know you from your courses or laboratory research work. Send your application by 20 February 2015 by email to fh111@cam.ac.uk.

Informal inquiries can be made by contacting Dr Florian Hollfelder - fh111@cam.ac.uk

Please quote reference PH05115 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

PhD Studentship: Protein Engineering by Phenotypic Screening in Microfluidic Droplets (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 13, 2015.

PhD Studentship in Chemical Biology and Protein Engineering Department of Biochemistry, University of Cambridge

Protein Engineering by Phenotypic Screening in Microfluidic Droplets

A graduate studentship leading to the award of a PhD is available from 1 October 2015 (or later) to work at Cambridge University in the Biochemistry Department (with Dr. F. Hollfelder - http://www.bioc.cam.ac.uk/hollfelder) and at MedImmune (with Dr. R. Minter - http://www.medimmune.com/).

Antibodies are usually raised against purified proteins, e.g. by affinity panning. In many cases this approach has led to valuable therapeutics, but good binders can also be therapeutically inactive, if the binding event is not linked to a biological effect. In a radical departure from conventional antibody screening, we will co-compartmentalise one antibody species with a single cell in pico- to nanolitre droplets that are generated at high speed (> >1kHz) in microfluidic devices. In this way we can screen millions of clones for their ability to alter cellular behaviour. Such an approach will be uniquely valuable to raise therapeutic molecules against targets that are relatively unstable, difficult to handle or cannot be produced in vitro, so that affinity panning is not an option. In the course of the studentship this new technology will be developed and applied and validated by addressing currently undruggable targets.

Candidates will be mainly based in the Biochemistry Department (in central Cambridge), but also work for extended secondments at MedImmune's Granta Park Site (near Cambridge) and/or in their US headquarters (Gaithersburg, Maryland) and thus receive training in a basic science as well as an industrial context.

Applicants should have a first or upper second class degree in biochemistry, biotechnology, chemistry or a related, relevant subject. Specific skills in protein engineering, directed evolution, cloning, DNA manipulation (including preparation and handling of DNA libraries) and familiarity with other molecular biology techniques (e.g. phage or ribosome display) are advantages.

This project is fully funded by the BBSRC (via a CASE award) for up to 48 months. Studentships are only available to citizens of the EU or the European Economic Area. To qualify for the full rate of the studentship UK residency requirements must be met (see e.g.

http://www.mrc.ac.uk/Fundingopportunities/Applicanthandbook/Studentships/Eligibility/index.htm#P17968 or http://www.bbsrc.ac.uk/web/FILES/Guidelines/studentshipeligibility.pdf).

The full stipend will be paid at RCUK rates for the 4 year duration.

Fixed-term: The funds for this post are available for 4 years in the first instance.

Applications should contain a description of your research interests (e.g. as part of the cover letter) and your detailed CV (with exam marks and all relevant practical experience). Please also include the names and email-addresses of at least two referees, who know you from your courses or laboratory research work. Send your application by 15 February 2015 by email to fh111@cam.ac.uk.

Informal inquiries can be made by contacting Dr Florian Hollfelder - fh111@cam.ac.uk

Please quote reference PH05109 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate in Virus-Host Interactions x 4

From Jobs at the University of Cambridge. Published on Jan 13, 2015.

Limit of tenure applies

Applications are invited for four postdoctoral vacancies in virus-host interactions.

Positions 1-3 are funded by a Programme grant from the Wellcome Trust and are available immediately and until 31/12/2019. The postholders will join a multi-disciplinary team studying poxvirus inhibition of host innate immunity.

Positions 1 and 2 will work in Prof Geoffrey L. Smith's laboratory based in central Cambridge and will study vaccinia virus proteins that block innate immune signalling and the contributions of these proteins to virus virulence and immunogenicity. Position 3 will work in Dr Stephen C. Graham's laboratory based at the Department's Addenbrooke's Hospital site and will use structural and biophysical techniques to characterise vaccinia virus immunomodulatory proteins alone or in complex with cellular binding partners.

Candidates should hold a PhD, or equivalent qualification, and have a track record of success in biomedical research. For the posts in Prof Geoffrey L. Smith's laboratory experience in virology, innate immunity and cell biology will be advantageous. For the position in Dr. Stephen C. Graham's laboratory experience in protein expression, purification, characterisation and structure solution by X-ray crystallography will be advantageous.

Post 4 will investigate subversion of autophagy by influenza and other viruses in the laboratory of Dr Rupert Beale based at the Department's Addenbrooke's Hospital site. Candidates will be expected to have a PhD in a relevant field, a strong background in molecular and cellular biology and an interest in host:pathogen interactions. Experience of molecular virology would be an advantage. This position is funded by a programme grant from the Medical Research Council and is available from 1/04/2015 until 31/03/2019 in the first instance.

For all the positions the ability to work both as part of a team, and independently, coupled with excellent communication, organizational and problem solving skills are required. The duties/responsibilities of these posts include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures.

The generic role description for a Research Associate is available at the following link: http://www.hr.admin.cam.ac.uk/files/researchassociate.pdf

The closing date for all applications is 10 February 2015. Interviews will be held on the 16-18 February 2015. Please specify which position you are applying for in your covering letter.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05065 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 12, 2015.

A postdoctoral position is available for 12 months (with a possibility of extension) from 1st March 2015 (or later) to work with Dr Florian Hollfelder in the University of Cambridge, Department of Biochemistry, Tennis Court Road, Central Cambridge on evolution and ancestral reconstruction of highly promiscuous enzymes (namely members of the alkaline phosphatase that catalyse up to 6 chemically distinct activities). We will base directed evolution of new generalists and specialists on measurement of fitness landscapes of randomised protein populations: such distribution functions for multiple activities will be gathered by ultrahigh-throughput screening of >106 clones in picolitre droplet compartments during in vitro and in vivo evolution cycles, followed by systematic characterization of multiple fitness traits such as expression level, stability or reaction kinetics. These approaches will enable a dynamic picture of protein evolution at various levels from transition state recognition, protein biophysics to population genetics. The project involves collaboration with the groups of Erich Bornberg-Bauer at Münster (http://ieb.uni-muenster.de/bioinf/people/ebb) and Nobu Tokuriki at Vancouver (http://www.msl.ubc.ca/faculty/tokuriki).

Candidates should have skills in molecular and chemical biology, protein engineering, yeast display, library selection techniques, in vitro protein expression and kinetic analysis of enzymes or alternatively micro engineering and droplet microfluidics.

Candidates should have a PhD or the equivalent in a relevant science.

Fixed-term: The funds for this post are available for 12 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made by contacting Dr Florian Hollfelder - fh111@cam.ac.uk

Please quote reference PH05098 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 12, 2015.

A postdoctoral position is available for 12 months (with a possibility of extension) from 1st March 2015 (or later) to work in the group of Dr Florian Hollfelder in the University of Cambridge, Department of Biochemistry, Tennis Court Road, Central Cambridge on identification and protein engineering of protease enzymes as potential therapeutics. The project will explore the substrate promiscuity of existing proteases to adapt them for new targets and develop new therapeutic molecules. To this end directed evolution of protease will be carried out using ultra-high-throughput screening in microfluidic droplets. Kinetic and biophysical analysis will be used to analyse the mechanisms of substrate recognition of the new biocatalysts. This project is a collaboration with Drs. Nat Gordon, Lutz Jermutus and others at MedImmune, the biologics arm of AstraZeneca based in Cambridge.

Candidates should have skills in molecular and chemical biology, protein engineering and kinetic analysis of enzymes.

Candidates should have a PhD or the equivalent in a relevant science.

Fixed-term: The funds for this post are available for 12 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made by contacting Dr Florian Hollfelder - fh111@cam.ac.uk

Please quote reference PH05105 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Cleaner (Part Time)

From Jobs at the University of Cambridge. Published on Jan 12, 2015.

We are looking to recruit an additional person to join our team of cleaners that provides cleaning to a high standard to the entire Department. The duties will include thorough cleaning of all areas, including research laboratories, offices, teaching and meeting rooms, kitchen, communal areas, stairways, and toilets. You will be required to work 15 hours per week, 6.00 - 9.00 am Monday to Friday.

No formal qualifications are required although NVQ 1 Cleaning Methods would be advantageous. Experience of laboratory and/or office cleaning, including experience using scrubber/polishing equipment would be beneficial. A good standard of English is required to ensure an ability to read and follow written and verbal instructions from supervisors and to understand user and safety instructions regarding the use of cleaning products and machinery. Due to the nature of the work, you also need to have a good level of physical fitness.

Please note that the building is currently undergoing a significant refurbishment, which is due for completion in August 2015.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Interviews to be held in early February.

Any queries should be directed to jobs@gen.cam.ac.uk

Please quote reference PC05083 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Two University Lectureships

From Jobs at the University of Cambridge. Published on Jan 12, 2015.

Applications are invited for two research-oriented, tenure-track University Lectureships. The posts are available from 1 October 2015 or as soon as possible thereafter. Based in central Cambridge, the Department of Genetics is a world class research and teaching environment with particular strengths in quantitative approaches to genomics, epigenetics, population and evolutionary genetics, cell and developmental biology and has numerous links with other local institutions. We are searching for outstanding scientists undertaking cutting edge and fundable research in any field of contemporary genetics relating to or complementing our existing research programmes. (http://www.gen.cam.ac.uk/research-groups/research-by-subject).

The successful applicants will have a PhD in a relevant subject area and will have demonstrated the potential to achieve international recognition for their research. Applicants will also have an aptitude and enthusiasm for teaching at undergraduate and graduate level and will be expected to contribute to the teaching and other academic activities in the Department. They will be expected to contribute to the design and delivery of undergraduate and graduate lecture courses and to perform other academic duties such as Departmental administration, examinations and other forms of assessment.

Appointments will be made at University Lecturer level with a probationary period of five years, with appointment to the retiring age thereafter. The starting salary, depending on experience, will be in the range of £38,511 - £48,743 per annum. Once an offer of employment has been accepted, the successful candidates will be required to undergo a health assessment, with a satisfactory outcome determined by the University.

Prospective candidates are invited to contact the Head of Department, Professor Anne Ferguson Smith, for informal enquires (Tel: +44 (0) 1223 339984, e-mail: head@gen.cam.ac.uk).

The Department is committed to the Athena SWAN scheme to provide equal opportunities and to advance the representation of women in science. We welcome applications from all qualified candidates irrespective of gender and we strongly encourage applications from female candidates. Appointment will be based on merit alone. The Department strongly supports DORA (http://am.ascb.org/dora/) and will assess research on its quality rather than on the basis of the journal in which it is published.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that in the Upload section of the online application you upload your Curriculum Vitae (CV), research publications list, highlighting your 3 most important published outputs and a covering letter of no more than 2 pages, outlining current and future research plans, with an emphasis on how the proposed research fits within the research profile of the Department, and how you might contribute to our teaching. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

Please quote reference PC05079 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate

From Jobs at the University of Cambridge. Published on Jan 09, 2015.

A 2.5 year Research Associate position to study the control of mitosis is available in the laboratory of Dr Jonathon Pines at the Gurdon Institute, University of Cambridge. The focus of the research project is on the Spindle Assembly Checkpoint and how this regulates the Anaphase Promoting Complex/Cyclosome. A PhD and a strong background in biochemistry is essential; some experience of protein purification and in vitro reconstitution assays would be an advantage.

Limited funding: The funds for this post are available until 30 September 2017 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please upload a covering letter explaining your suitability for the role and a CV.

Please quote reference PR05091 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity. Benefits include generous maternity/paternity leave, flexible working and funds for returning carers and other family friendly schemes.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 09, 2015.

Applications are invited for a full time postdoctoral position in the laboratory of Prof. Christine Watson, based at Department of Pathology, central Cambridge, to investigate non-apoptotic cell death mechanisms in mammalian cell culture and in vivo. Ambitious, enthusiastic individuals are invited to apply for this position which is funded by the Medical Research Council.

Candidates will be expected to have a PhD in a relevant field with a track record of publishing in high quality journals, a strong background in molecular and cell biology, expertise in imaging and genetic modification technology, and an interest in signaling and mechanisms of cell death in normal and cancer cells. Ability to work both as part of a team, and independently, coupled with excellent communication, organizational and problem solving skills are essential. The duties/responsibilities of this post include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures.

Specific enquiries, and requests for more details of the project, can be made to Christine Watson at cjw53@cam.ac.uk.

Fixed-term: The funds for this post are available until 13 May 2017 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK04787 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate in Molecular Virology x 2 (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 09, 2015.

Limit of tenure applies

Applications are invited for two postdoctoral vacancies in molecular virology to join a multi-disciplinary team studying vaccinia virus: host interactions. Both positions will work in Prof Geoffrey L. Smith's laboratory based in central Cambridge.

Post 1 will study vaccinia virus proteins that block innate immune signalling and the contributions of these proteins to virus virulence and immunogenicity. This post is funded by a programme grant from the Wellcome Trust and is available immediately and for a period of 12 months from the date of appointment. Experience in virology, innate immunity and cell biology will be advantageous.

Post 2 will study how vaccinia virus exploits actin and microtubule-based transport to spread within and between cells. This position is funded by a grant from the Medical Research Council and is available immediately and until 31/12/2015. Experience in virology and cell biology will be advantageous.

Candidates should hold a PhD, or equivalent qualification. The ability to work both as part of a team, and independently, coupled with excellent communication, organizational and problem solving skills are required. The duties/responsibilities of these posts include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures.

The closing date for both positions is 30 January 2015 and interviews will be held on 5th or 6th February 2015. Please specify which position you are applying for in your covering letter.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05099 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 09, 2015.

Fixed-term: The funds for this post are available until 31 July 2016 in the first instance.

Location: Central Cambridge

The Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute (SCI) comprises 200 researchers spanning fundamental science through to clinical applications. Our goal is to advance disease modelling, drug discovery and regenerative medicine through understanding the genetic and biochemical mechanisms that control stem cell fate.

The full time position advertised is for a postdoctoral research associate with a PhD in mammalian biology to work with Kevin Chalut and Jenny Nichols investigating the physical biology and biomechanics of the early mouse embryo. Specifically, the researcher will be exploring how cell mechanics drives early fate decisions.

We are looking for a highly motivated researcher with extensive experience in mouse embryology. In particular, a practical understanding of early mouse development, transgenic technology and chimaera generation is essential.

It would be helpful for the researcher to have some background in physical sciences or engineering but it is not necessary; experience with atomic force microscopy is preferred.

The main duties and responsibilities will include managing breeding programmes for the provision of specifically staged embryos, embryo manipulation, measurements of physical properties, confocal microscopy and live imaging.

The successful candidate will be expected to participate in lab meetings, departmental seminars and writing up experimental findings for publication.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Sunday 8th February 2015.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Informal enquiries are also welcome via e-mail to cscrjobs@cscr.cam.ac.uk.

Interviews will be held on the Monday 16th February 2015. If you have not been invited for interview by 12th February 2015, you have not been successful on this occasion.

Please quote reference PS05089 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 08, 2015.

Molecular Parasitology: MRC funded postdoctoral research position

Targeted investigation of the molecular composition and function of the apical complex in Toxoplasma.

Skill sets: Molecular biology, cell biology, tissue culture, microscopy.

A position is available for a post-doctoral research worker to apply state-of-the-art technologies to investigate the molecular composition and function of the apical complex in Toxoplasma gondii. Protein discovery, tagging, knockdown and knockout strategies will be employed to examine the molecular behaviour and mechanisms associated with the function of this iconic feature of apicomplexan parasites. The outcomes of this project will contribute to better understanding of the apical complex's significance to invasion, cell replication, and other aspects of apicomplexan biology.

The position will be based in the Department of Biochemistry, Tennis Court Road at the University of Cambridge (central Cambridge) in the laboratory of Dr Ross Waller.

Candidates should have a PhD in cell and molecular biology, preferably with experience in parasitology and a track record of publishing in high quality journals. Ability to work both as part of a team, and independently, coupled with excellent communication, organizational and problem solving skills are required.

The host laboratory provides cell culture, molecular biology, and wide-field fluorescence microscopy facilities, and provides access to super-resolution and electron microscopy, as well as advanced proteomics. The project is supported by a technician.

The position is available from 1st March 2015, and is funded for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made by contacting Ross Waller (rfw26@cam.ac.uk).

Please quote reference PH05081 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 07, 2015.

Applications are invited for a Postdoctoral Research Associate to join a multidisciplinary team in Cambridge, where the group focuses on a range of algal molecular biology and biotechnology projects. The research effort builds on extensive complementary expertise in groups at the Universities of York, Reading and Cambridge, as well as close collaboration with several companies. The aim is to develop new production platforms for high value diterpenoids, pathways and enzymes for the biosynthesis of which have been identified at York. These genes will be overexpressed in different production hosts including higher plants, yeast and algae.

The PDRA will work in the group of Prof Alison Smith to carry out metabolic engineering of microalgae to express genes for enzymes of plant diterpenoid biosynthesis. The approach taken will involve a synthetic biology pipeline, including the establishment of regulatory genetic circuits.

The successful candidate must have a PhD in molecular biology, microbiology, biochemistry or a closely related field, or have submitted a PhD thesis in one of these fields by the start of the appointment. Research experience in molecular biology (ideally including synthetic biology approaches), and genetic engineering of microorganisms, together with a good knowledge of regulation of gene expression and metabolism is essential. Experience with laboratory handling of microalgae or microbiology, and/or analysis of RNA seq data, is highly desirable.

Fixed-term: The funds for this post are available for 5 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should provide a CV, the filename of which should be "CV-followed by your name", including contact details of two or more referees, and a covering letter addressing the selection criteria.

For further information contact Prof Alison Smith (as25@cam.ac.uk) or see http://www.plantsci.cam.ac.uk/research/alisonsmith

Please quote reference PD05074 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

BBSRC Targeted PhD Studentship in Human Ageing

From Jobs at the University of Cambridge. Published on Jan 07, 2015.

Applications are invited for a 4-year BBSRC Targeted PhD studentship starting in October 2015 to conduct research under the supervision of Dr Jon Simons and Professor Zoe Kourtzi at the Department of Psychology, University of Cambridge. The Research Project is titled: "Neurocognitive Analysis of Ageing and Human Memory" The project will investigate the ability of older adults to recollect the context in which events were experienced, and explore potential strategies that might enhance learning and retention, leading to reduced age-related decline. These strategies might include the use of deep, elaborative learning tasks that can promote the formation of rich, vivid memory traces. Neuroimaging data could be used to explore the brain networks that might support age-resistant elaborative memory processes, investigating the hypothesis that brain regions linked to effective learning may be, in relative terms at least, less disrupted by the ageing process than other areas. If successful, the results of this project could be applied to develop learning and memory-related cognitive training techniques that could produce potentially long-lasting enhancement of remembering in older adults.

PhD students will have the opportunity to gain experience in a range of interdisciplinary cognitive neuroscience methods used in the Memory Laboratory (http://www.memlab.psychol.cam.ac.uk) and Adaptive Brain Laboratory (http://www.abg.psychol.cam.ac.uk) during two first-year placements, including behavioural studies, functional neuroimaging (fMRI), electrophysiology (EEG/MEG), and brain stimulation (TMS/tDCS), before completing their PhD studies in the Memory Laboratory under the supervision of Dr Simons and Professor Kourtzi. Students will be provided with an extensive training in research methods and techniques, and will be a member of the Cambridge Graduate Programme in Cognitive and Brain Sciences which includes regular theoretical seminars and courses.

Eligibility and Funding: Candidates should have a first or upper second class degree in psychology, neuroscience or in another related subject (e.g., physiology, mathematics, computer science, engineering) and meet the University of Cambridge entrance requirements - see: http://www.admin.cam.ac.uk/students/gradadmissions/prospec/studying/entryreq/index.html. All applicants must meet the BBSRC funding eligibility requirements outlined at: http://www.bbsrc.ac.uk/web/FILES/Guidelines/studentship_eligibility.pdf

UK and EU students who meet the UK residency requirements will be eligible for a full studentship, which includes University fees as well as an annual stipend at UK Research Council rates (£13,863 for year 2014/15). Students from EU countries who do not meet the residency requirements may still be eligible for a fees-only award. Candidates from Overseas are not eligible for this studentship and should not apply. Informal enquiries about the project may be made to Dr Jon Simons (jss30@cam.ac.uk).

To apply please e-mail (i) a covering letter outlining your suitability, why you are interested in pursuing a PhD in this area, and any other information relevant to the application, (ii) your CV stating your citizenship and years of residence in the UK (iii) copies of your academic transcripts and (iv) contact details for two academic referees (one of whom should be a project supervisor) to Dr Rachel MacDonald (rmm73@cam.ac.uk) by 30 January 2015. Please add 'BBSRC Ageing Studentship' to the subject line of your e-mail. Shortlisted candidates will be invited to an interview in February 2015. Once the successful applicant is informed of the outcome, they will be asked to complete the University's GRADSAF application form. The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

BBSRC PhD Studentship

From Jobs at the University of Cambridge. Published on Jan 05, 2015.

A BBSRC PhD studentship fully funded for four years is available in the laboratory of Professor Paul Dupree. The project is in partnership with Novozymes, the world's largest enzyme discovery and production company.

The industrial collaborative project aims to develop tools and understanding with application to the bioenergy, biorefining and dietary uses of plants. The project goal is to understand the role of the plant cell wall polysaccharide xylan in preventing enzymatic digestion of cellulose microfibrils. Our recent discoveries propose new models for xylan interaction with cellulose (Busse Wicher et al. 2014). The new models suggest new types of enzymes may be involved in plant cell wall deconstruction. The project will use the extensive range of specific recombinant hydrolases and polysaccharide oxidases (e.g. cellulases, xylanases, LPMOs) available from Novozymes, and also the extensive panel of plants with modified plant cell wall synthesis available in the laboratory of Paul Dupree.

The student will spend at least three months in Novozymes, Copenhagen, gaining experience of industrial enzyme discovery and development.

The project will start during the 2015-2016 academic year.

Busse-Wicher M et al. (2014) The pattern of xylan acetylation suggests xylan may interact with cellulose microfibrils as a two-fold helical screw in the secondary plant cell wall of Arabidopsis thaliana. Plant J. 79(3):492-506.

Please contact Professor Paul Dupree - pd101@cam.ac.uk for any enquiries.

BBSRC studentship eligibility conditions apply.

http://www.bioenergy.novozymes.com

Please quote reference PH04924 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Principal Clinical Oncologist / Clinical Veterinarian in Oncology

From Jobs at the University of Cambridge. Published on Dec 22, 2014.

Principal Clinical Oncologist / Clinical Veterinarian in Oncology

Principal Clinical Oncologist Grade 11 Stipend £58,172.00 or

Clinical Veterinarian in Oncology Grade 9 £38,511.00 to £48,743.00

Limit of Tenure 3 years in the first instance

The Department wishes to appoint an individual, to further develop the national and international reputation of the Department of Veterinary Medicine and the University of Cambridge for excellence in research and the teaching of Veterinary Oncology by supporting and maintaining the high standard of clinical service provision.

The Principal Clinical Oncologist / Clinical Veterinarian in Oncology will play a key role in developing the Cancer Therapy Unit as a stand-alone veterinary facility and will promote the clinical service and research aspects of this nationally and internationally.

S/he will be responsible for the day-to-day organisation and management of the Oncology service and will be responsible for developing, with the support of the Clinical Services Manager, the business aspects of the Cancer Therapy Unit, and to this end will formulate medium and long-term strategies for the management and direction of the Oncology service. This will include agreeing and meeting annual targets for the sustainability of staffing and the profitability of the Unit.

The role will take a lead in the training of postgraduate Senior Clinical Training Scholars and clinical rotation teaching of students. The roleholder will participate personally in the service work of The Queens' Veterinary Hospital, including its out of hours emergency work.

Applicants appointed at the Principal level should be a member of the Royal College of Veterinary Surgeons, and hold a Diploma of the European or American College of Veterinary Internal Medicine ¿ subspeciality Oncology and have substantial experience at a senior level in veterinary clinical oncology. An in-depth understanding of the requirements of veterinary referral hospital work is essential. Applicants considered for appointment to the Clinical Veterinarian in Oncology should be a member of the Royal College of Veterinary Surgeons, and hold a Diploma of the European or American College of Veterinary Internal Medicine subspeciality Oncology, but candidates who have completed an approved Residency training programme in Medical Oncology and who are eligible to sit the ECVIM-Onc certifying examination, will also be considered. Documented undergraduate teaching experience is desirable.

Closing date for applications 5th February 2015

Interview date 18th February 2015

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should submit a CHRIS/6, CV, covering letter outlining suitability for the role and contact details for two references. Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application. Further particulars for the role and information about the Department www.vet.cam.ac.uk

Please quote reference PP05036 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate (Drosophila Gene Function Analyst)

From Jobs at the University of Cambridge. Published on Dec 19, 2014.

FlyBase (http://flybase.org/) seeks a research assistant/associate to join our group at the University of Cambridge, UK. This is a fly-related post away from the bench, assisting Drosophila research by contributing to the FlyBase database of genetic and genomic data. If you have been frustrated by the lack of simple summaries of fly gene function in the FlyBase gene reports, here is your opportunity to fix that, by soliciting, editing and writing such summaries.

The primary aim of FlyBase-Cambridge is to identify biological data from scientific articles concerning Drosophila and to record these data in a systematic manner. Curated data are subsequently integrated into the FlyBase database and website to aid the international research community. The successful applicant will contribute to this effort by editing and writing short gene function summaries, and also making sure these functions are represented with the standardized terms of Gene Ontology annotation (geneontology.org). Liaison with other members of the Gene Ontology consortium will ensure accurate and up to date annotations.

Depending on their previous experience, the successful applicant may also highlight sets of genes involved in a pathway or function, or liaise with the Drosophila research community and FlyBase's software developers to improve the display and searching of Gene Function and Gene Ontology annotations in FlyBase.

Essential skills/experience include:

  • a biological sciences degree
  • research experience using Drosophila
  • excellent written English
  • strong self-motivation and ability to work as part of a team

Useful skills/experience include:

  • familiarity with databases
  • programming
  • knowledge of biomedical ontologies
  • annotation/curation experience

Limited funding: The funds for this post are available for 18 months in the first instance.

Interviews are anticipated to occur the week of 16 February 2015.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please upload a covering letter explaining your suitability for the role and a CV.

Please quote reference PR05021 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Trainee Horticultural Technician

From Jobs at the University of Cambridge. Published on Dec 16, 2014.

Each year vacancies under the Trainee Technician scheme are available for people wishing to pursue a career in horticulture by gaining practical experience. The training is for a period of one year starting at the beginning of September. Based within the 40-acre Botanic Garden, the trainees are able to learn and perform the wide range of horticultural skills that are required to maintain a diverse collection of over 8,000 plants, which is of international importance. The scheme is demanding and is intended for those wishing to gain experience in practical horticulture, collection management and plantsmanship. Trainees are part of the staff of the Botanic Garden and receive a salary.

Trainees who successfully complete the scheme will be awarded a Certificate of Higher Education in Practical Horticulture and Plantsmanship by the University of Cambridge Institute of Continuing Education, which works closely with the Botanic Garden. This award attracts 120 credits (Credit Accumulation Transfer [CAT] Points) at FHEQ level 4 (first-year undergraduate level). By the end of the course, students should be able to:

  1. Demonstrate a critical understanding of the roles of botanic gardens
  2. Discuss and review issues relating to plant diversity and conservation
  3. Demonstrate their ability and skill to cultivate and manage plant collections according to scientific principles

The trainees work with experienced Garden staff and rotate between the horticultural sections in the Garden: Trees and Shrubs; Demonstration and Display; Systematic Beds; Alpine and Woodland; Experimental; Glasshouse; Landscape and Machinery. Trainees work on each section, enabling them to experience how the management of each section changes with the seasons. The trainees form a significant proportion of the Garden's workforce and are central to its horticultural operations. The practical training is augmented by a weekly programme including talks, seminars, demonstrations, plant identifications, and visits to other gardens and sites of botanical significance. Trainees must attend all teaching sessions during the year in order to complete the qualification. There is an emphasis on plant diversity, basic taxonomic training and plant identification utilising the plant collections.

Fixed-term: 12 months.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Interviews are expected to be held during the week beginning 30 March 2015.

For any questions relating to this post, please contact admin@botanic.cam.ac.uk

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate (Computational) (Fixed Term)

From Jobs at the University of Cambridge. Published on Dec 16, 2014.

Applications are invited for a Post-doctoral Research Associate position in the group of Dr Sebastian Schornack (http://www.schornacklab.net) at the Sainsbury Laboratory (SLCU), Cambridge University, to use computational approaches in comparative studies of organ specific oomycete colonisation processes in barley, wheat, Medicago and Nicotiana plants.

The overall aim of this project is to elucidate general and organ specific processes (in leaves and roots) using differential transcriptomics and microscopical image analyses. The successful candidate will be broadly responsible for bioinformatics based analysis of obtained sequence and microscopy image information and will identify sets of specifically regulated pathogen and host genes. The successful post holder will be able to develop further research objectives and proposals such as evolutionary aspects of colonisation processes in the frame of our general research.

Candidates must have or be close to obtaining a PhD in a relevant discipline, e.g. computer science, statistics, theoretical physics or bioinformatics. Salary will be commensurate with knowledge and experience. The current salary scale is £28,695 to £37,394 p.a. (Research Associate) or £24,775 to £27,864 p.a. (Research Assistant), depending on experience and qualifications. Exceptional Master's degree applicants may be considered for this position but will be appointed on the Research Assistant scale.

The successful applicant should have expertise in computational approaches for analysis of genome-wide information derived from next generation sequencing. Previous knowledge of plant science is not a prerequisite and candidates from animal or microbial sciences are encouraged to apply. However, a keen interest in transcriptome and genome based studies of plant-microbe-interactions is essential. The successful candidate will be fully involved in the basic research in these areas whilst also writing up their research work for presentation and publication. The post holder may be required to assist in the supervision of student projects, provide instructions to students and deliver seminars relating to their research area.

Good communication skills are essential as the post holder will need to work well in a team and collaborate with other researchers in the Institute. Candidates would ideally have published or submitted papers in this area. Candidates should demonstrate a history of science communication (e.g. presentations, outreach activities, teaching).

Information about the Sainsbury Laboratory and the generic further particulars for the role can be found at: http://www.slcu.cam.ac.uk/

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within three weeks of the closing date, please consider your application as unsuccessful on this occasion.

Fixed-term: The funds for this post are available for 2 years in the first instance.

Please ensure that you upload a copy of your full CV, a supporting statement and contact information of three referees.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PT04991 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

MRC 4-yr PhD Programme in Stem Cell Biology and Medicine: 'Physical Biology of Stem Cells'

From Jobs at the University of Cambridge. Published on Oct 30, 2014.

Programme Overview:

This studentship is targeted to applicants with a Physical Sciences, Mathematical or Computational Sciences background, who are interested in applying their training to aspects of stem cell biology.

This programme provides students with an opportunity to spend time in three different labs during their first 'rotation' year, before deciding where to undertake their thesis work for years 2-4.

Physical Biology of Stem Cells:

Stem cells are defined by their dual capacity to self-renew and differentiate into somatic cells. Great inroads have been made towards understanding how stem cells generate tissue and sustain cell turnover in tissue. At this time most of the inroads have been made by studying the individual biochemistry of the stem cell; much less progress has been made in understanding their function across scales - from molecules to tissue - or how they interact with their physical environment.

In studying the physical biology of stem cells, the aim is to identify and characterise the importance of physical, chemical, mathematical, and engineering considerations in the function of stem cells. This could include mathematical modelling of homeostasis in tissues, engineering controlled environments to control stem cell function, imaging and biotechnology, using single molecule approaches to study molecular interactions, systems biology, or investigating the importance of the stem cell's response to forces in its environment. The research generated by the MRC studentships should provide new foundations for biomedical discovery, biotechnological and biopharmaceutical exploitation, and clinical applications in regenerative medicine.

Qualification Eligibility:

We welcome applications from those who hold (or expect to be awarded) a relevant first degree at the highest level. You should have a passion for scientific research, specifically with a Physical Sciences, Mathematical or Computational Sciences background.

Financial Support:

All applicants must meet the MRC funding eligibility requirements outlined at http://www.mrc.ac.uk/skills-careers/studentships/studentship-guidance/student-eligibility-requirements/

Application Process:

Please visit http://www.stemcells.cam.ac.uk/studentships/phy-biol-2015/ for full details. Please note you will be required to complete and submit a departmental application form, provide two references and upload copies of your transcripts as part of the application process.

Application Deadline: 4th February 2015

Interview Date: 4th March 2015

Visit http://www.physbio.group.cam.ac.uk/ for details of the current Cambridge Physical Biology network.

Please email cscr-phd@cscr.cam.ac.uk for any further questions.

Please quote reference PS04621 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

PhD Studentship

From Jobs at the University of Cambridge. Published on Oct 23, 2014.

Project Title: Genotypic and environmental factors affecting canopy expansion and duration in potato

Supervisor: Professor Howard Griffiths with Dr David Firman NIAB ¿ Cambridge University Farm

Project outline:

The yield of potato crops is affected by the size and longevity of the leaf canopy and better quantification of the effects of factors influencing canopy duration will enhance crop models, enable yield improvement and guide breeding of new varieties. Important factors known to affect canopy expansion and duration include stem density, temperature and soil conditions including nutrient and moisture content. The extent to which each of these factors affect yield can vary considerably but by understanding their influence on the parameters and output of crop models, it should be possible to predict the effects more effectively than through use of empirical experiments alone. Potato breeding has generally achieved limited improvement in yield compared with other major crops which is at least partly due to the large number of other traits breeders select for. Quantifying genetic variation in some key characteristics of canopy expansion and duration will help determine the extent to which light interception could be increased in new varieties leading to improvements in yield.

Our research group has a strong interest in using data from field experiments and commercial crops to inform crop models for predicting yield, water and nutrient use. We are interested in establishing the role of environmental and genetic factors that affect crop growth. Close interaction with members of Cambridge University Potato Growers Association provides access to all sectors of the potato industry and enables rapid adoption of research findings into practice.

This project is expected to involve collating historical data on canopy production and duration from a range of varieties and environmental conditions and complementing this with new data from field experiments and commercial crops from a wide range of varieties. Analysis of these datasets will be carried out to derive characteristics of canopy expansion and duration and quantify the effects of genotype and environmental factors on these characteristics. The project is an opportunity to develop a broad range of skills in agronomy, data analysis, modelling and understanding of potato production in practice.

This studentship is fully funded by CUPGRA (Cambridge University Potato Growers Association). CUPGRA encourages study and research on potatoes and promotes the interchange of scientific research and field practice for innovative, sound commercial production of potatoes through its association with the Agronomy Research Group at NIAB-CUF.

The studentship will cover a stipend at the standard Research Council rate, research costs and tuition fees at the UK rate.

For informal discussion on the project please contact Dr David Firman david.firman@niab.com

Applications should include two academic referees, CV and cover letter and be emailed to Megan Cooper (mc661@cam.ac.uk).

Please quote reference PD04553 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.