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Research Associate (Chalut & Franklin Lab) (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 05, 2015.

Fixed-term: The funds for this post are available for 3 years in the first instance.

The Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute (SCI) comprises 200 researchers spanning fundamental science through to clinical applications (http://www.stemcells.cam.ac.uk/). Our goal is to advance disease modelling, drug discovery and regenerative medicine through understanding the mechanisms that control stem cell fate.

We are seeking an enthusiastic and highly motivated person to join the SCI to be co-supervised by Dr. Kevin Chalut and Prof. Robin Franklin. This project, which is also a collaboration with Dr. Ulrich Keyser in the Department of Physics, will investigate the role of the mechanical and material properties of the cell nucleus in regulating cell fate decisions. This BBSRC-funded project, continues our recently published work (Pagliara, et al., Nature Materials, 2014), which outlined the role of force-induced changes in nuclear shape and volume during stem cell differentiation.

We are seeking motivated researcher with a proven track record of successful research. The candidate must have a PhD in Physics or Biology or at the interface. It is essential that the candidate is driven to use principles of physics to better biological questions. The successful applicant should have experience in molecular biology techniques, cell culture and advanced microscopy. It would be beneficial for the candidate to have experience in biophysical techniques such as microfabrication and/or atomic force microscopy. In this collaborative project the candidate will need to show their ability to work within a highly interdisciplinary team.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Sunday 5th April 2015.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Informal enquiries are also welcome via email: cscrjobs@cscr.cam.ac.uk.

Interviews will be held on Thursday 16th April 2015. If you have not been invited for interview by 13th April 2015, you have not been successful on this occasion.

Please quote reference PS05553 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Junior Clinical Training Scholarship Farm Animal Health and Production (2 Scholarships available)

From Jobs at the University of Cambridge. Published on Mar 04, 2015.

UNIVERSITY OF CAMBRIDGE DEPARTMENT OF VETERINARY MEDICINE

Fixed-term: One-year Junior Clinical Training Scholarship

Scholarship award: £14,700

Start date 1 August 2015

Applications are invited for this 12-month Scholarship programme, which provides an opportunity for new graduates or recently qualified veterinarians to receive high-quality postgraduate training in farm animal studies under the supervision of experienced farm animal clinicians in the Cambridge Farm Animal Veterinary Services ambulatory and referral practice at the University of Cambridge. The emphasis of the programme is on gaining practical clinical experience in farm animal medicine and herd health, and will allow the Scholar to identify specific fields of farm animal work in which to specialise, either in preparation for Senior Clinical Training Scholarship programmes, or for specialist private practice.

The internship will cover:

  • Case management of individual production animals, including emergency and critical care, surgery, anaesthesia, diagnostics, internal medicine and obstetrics

  • Involvement in a busy and expanding first opinion farm animal practice

  • Training and practice in population medicine and herd health management, with an emphasis on evidence-based medicine

  • Experience in teaching and communication

  • Basic tuition in research methods and scientific writing

  • Opportunity to design and undertake research projects

An applicant must be a Member of the Royal College of Veterinary Surgeons, or hold a veterinary degree qualifying him/ her for membership.

Closing date: 31 March 2015

Interview date: 17 April 2015

Informal enquiries about scholarship programme: contact Ian McCrone, ism27@cam.ac.uk, 01223 764964 or Paul Wood, pw371@cam.ac.uk, 07500 883637.

Application form (JCTS1) and information pack: download from link below.

Completed application form, curriculum vitae, covering letter: send to Melissa Large, Department of Veterinary Medicine, Madingley Road, Cambridge, CB3 OES, or via email to vetmed@hermes.cam.ac.uk

Please quote reference PP05538 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Marie-Sklodowska-Curie ITN PhD Studentship

From Jobs at the University of Cambridge. Published on Mar 03, 2015.

A 3-year EU-funded PhD studentship is available in the laboratory of Dr Martin Welch. Applications are invited for a PhD studentship position ("Early Stage Researcher" or ESR) to be funded by the Marie-Sklodowska-Curie Innovative Training Network "INTEGRATE ¿ Interdisciplinary Training Network for Validation of Gram-Negative Antibacterial Targets" within the Horizon 2020 Programme of the European Commission. Researchers are required to undertake trans-national mobility (i.e., move from one country to another) when taking up the appointment.

Project Title: The glyoxylate shunt as a target for antibacterial intervention in Gram-negative bacteria.

The junction between the TCA cycle and the glyoxylate shunt is widely regarded as one of the most important metabolic branchpoints in the whole of microbial metabolism, and is increasingly being recognized as a major new target for the development of antibacterial compounds (Munoz-Elias & MacKinney, Nature Medicine 11, 638 - 44 (2005) & Sharma et al. Nat Struct Biol. 7(8):663-8 (2000)). In addition, carbon flux through the glyoxylate shunt plays a central role in regulating virulence in the Gram-negative "superbug", Pseudomonas aeruginosa (Chung et al, Open Biology (2013)). Indeed, mutants defective in isocitrate lyase (ICL; the first enzyme of the glyoxylate shunt) display impaired fitness in vivo. Consequently, compounds that target the enzymes of the glyoxylate shunt, or which reduce the flux of carbon directed through this pathway, may have the dual effect of reducing tissue damage (by blocking virulence) and diminishing the metabolic fitness of the organism in the niche. However, the branchpoint between the TCA cycle and glyoxylate shunt in P. aeruginosa differs markedly from the canonical organisation in E. coli, and nothing is known about its enzymology. The aim of this PhD project is to purify the enzymes involved, and to characterize these in considerable detail as potential targets for antimicrobial intervention. The kinetic parameters of each P. aeruginosa branchpoint enzyme (which includes two isocitrate dehydrogenases (ICD and IDH), a kinase/phosphatase (AceK) and ICL) will be determined, as will the impact of putative allosteric regulators. HTP screening of compound libraries (including natural product and Diversity oriented synthesis (DoS) libraries, available in-house) will be carried out to identify inhibitors/activators of each enzyme. We will characterize the nature of the inhibition/activation mechanisms (competitive, non-competitive, etc.) and attempt to co-crystallize these compounds as complexes bound to their cognate target enzymes.

The appointed ESR will spend at three months seconded to Aptuit (Verona, Italy) and five months seconded with the University of Helsinki (Finland) to allow them to learn and apply new techniques.

Shortlisted candidates will be invited the INTEGRATE Recruitment Event in Verona (Italy) on 5-6 May 2015. The Recruitment Committee will subsequently interview each candidate. In order to cover (part of) your travel and lodging costs, shortlisted candidates will receive a lump sum of €250.

The project will start during the 2015-2016 academic year.

An online application form is available by clicking;

http://www.cdr.fi/news-and-events/integrate-etn-student-application-form

The deadline for applications routed through the above website is March 9th, but Dr welch will still consider applications from exceptional individuals until the end of April. If you wish to apply for this position after March 9th, or if you have any queries regarding the position, please contact Dr Welch directly - mw240@cam.ac.uk .The Welch lab website can be found at: http://www.bioc.cam.ac.uk/people/uto/welch

Please quote reference PH05532 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate [Temporary Cover] (Maternity Cover)

From Jobs at the University of Cambridge. Published on Mar 03, 2015.

A temporary postdoctoral research associate position is available for a period of 6 months to work in the laboratory of Professor Ernest Laue at the Department of Biochemistry, University of Cambridge, Tennis Court Road, Central Cambridge.

The Laue group is interested in the way chromatin structure controls epigenetic inheritance, and the study of proteins and complexes involved in chromatin assembly/disassembly. Our current research is focussed on studies of the Nucleosome Remodelling Deacetylase complex (NuRD), as part of the EU FP7 project '4DCellfate'. NuRD plays a key role in controlling the differentiation of embryonic stem (ES) cells and the reprogramming of adult cells to a pluripotent state.

We are looking for an experienced biochemist with expertise in the expression/purification of protein complexes. The project will involve expression of NuRD complexes in insect cells, e.g. using the MultiBac system. The project would also suit a structural biologist, ideally with some background in X-ray crystallography or Electron Microscopy (EM), who has good expertise in biochemical methods.

Applicants should have a PhD or equivalent in a relevant area of science.

Maternity cover: This post is fixed-term for 6 months or the return of the post holder, whichever is the earlier.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For all informal inquiries, please contact Professor Laue - e.d.laue@bioc.cam.ac.uk

Please quote reference PH05520 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Curator/ University Lecturer in Vertebrate Palaeontology (Tenure Track Position)

From Jobs at the University of Cambridge. Published on Mar 03, 2015.

We seek to recruit an outstanding scientist to join the staff of the Department and Museum of Zoology at Cambridge. The successful candidate will combine excellence in research with a commitment to teaching at both undergraduate and graduate levels. In addition he/she will have the ability to engage with the work of the Museum in collections development, outreach and public engagement.

We seek a candidate with the ambition and ability to fund and lead a world-class research group. For this post, we are likely to appoint a candidate whose research is collections-based. The appointee will take overall academic responsibility for the vertebrate palaeontology collections, working with professional collections management staff, who will undertake the routine management of the collections.

The selection criteria for this post are:

Essential

An outstanding research record, documented by publication and by the demonstrated ability to attract research funding.

An innovative and focused research agenda in vertebrate palaeontology.

Experience of working with Museum collections, and an engagement with the process of biological and, when appropriate, geological curation.

The training and expertise to contribute broadly to undergraduate teaching in the area of vertebrate evolutionary biology.

Desirable

Curatorial experience in a major research museum.

Taxonomic expertise relating to an area relevant to the Museum's existing collections.

A programme of research that will enhance and develop the collections of the Museum.

Demonstrated excellence in teaching undergraduates and supervising research students.

A track record of commitment to wider responsibilities in a current or previous institution (for example, in research leadership, museum development, or public engagement).

The duties and responsibilities of this post will be:

To conduct research in some area of Vertebrate Evolutionary Biology and Palaeontology.

To teach undergraduate and graduate students in Evolutionary Biology and related disciplines.

To take curatorial responsibility for the vertebrate palaeontology collections.

To promote outreach and public engagement

Appointment will be from 1st Oct 2015, with some possibility for flexibility.

Appointment will be for a probationary period of five years with appointment to the retiring age thereafter, subject to satisfactory performance.

The Department would particularly welcome applications from women as we have an historical imbalance in the number of women holding academic staff positions.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PF05523 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 02, 2015.

Applications are invited for a postdoctoral researcher to work in the laboratory of Dr Catherine Lindon, Department of Pharmacology, University of Cambridge on a project studying ubiquitination events in the cell cycle. The project will involve large-scale preparation of cells and biochemical purification of ubiquitinated material for proteomic profiling, alongside time-resolved single cell assays to probe cell fates associated with specific ubiquitination events.

The role holder will be based in Central Cambridge. The key duties and responsibilities will include but not be limited to: developing research objectives and conducting the research project, analysing and communicating results to the team, writing up research work for presentation and publication, continually updating knowledge and understanding in the field, translating knowledge of advances in the subject area into research activity, managing own research and administrative activities, communicating material of a specialist or highly technical nature, supervising PhD students and undergraduate lab projects. The role holder will be strongly encouraged and need to be prepared to apply for fellowship funding where possible as well as assist in the preparation of proposals and applications to external bodies for funding.

The work will suit a researcher with a PhD in molecular cell biology and research background in the study of ubiquitin pathways. Successful candidates will be expected to have knowledge of literature in the ubiquitin field and demonstrable experience in one or more of the following areas: mammalian cell culture, proteomics, quantitative time-lapse imaging. Preference will be given to candidates with previous experience in using proteomics to study post-translational modifications.

To prospective candidates: You must be a careful and methodical worker, paying attention to accuracy and ready to take responsibility individually as well as part of a team. You should be self-motivated and able to organise, perform and analyse experiments with minimal instruction. You will be expected to present and discuss the work both within the research group and with wider audiences.

The funds for this post are available for up to 3 years with effect from 1st May 2015 or as soon as possible thereafter. The starting salary, depending on experience, will be in the range of £28,695 - £37,394 per annum.

Informal enquiries about the position can be made to Dr Catherine Lindon (acl34@cam.ac.uk).

The Department holds an Athena SWAN bronze award, demonstrating a commitment to provide equal opportunities and to advance the representation of women in science subjects. We welcome applications from all qualified candidates irrespective of gender but, as women are currently under-represented at this level in our department, we strongly encourage applications from female candidates. Appointment will be based on merit alone.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The online application is to include your personal details, names and addresses of referees, as well as your CV, research publications list and cover letter. For enquiries about the online application process please contact Ms Anna Osipova at recruitment@phar.cam.ac.uk.

Interviews will take place in April 2015.

Please quote reference PL05508 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Fieldwork Research Technician (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 02, 2015.

An exciting opportunity is available in the Department of Plant Sciences to help establish and work on a whole-lake experiment in Sudbury, Ontario; Canada's "City of Lakes" on the doorstep of the vast boreal wilderness.

We are seeking a highly motivated and independent person to spend much of the next 2.5 years based in the field, measuring water quality and monitoring phytoplankton and aquatic invertebrate communities. The postholder will be working out of the Vale Living with Lakes Centre (http://www3.laurentian.ca/livingwithlakes/), an award-winning and internationally recognized centre of excellence in studying aquatic ecosystems. Lab work will include identifying and enumerating samples collected in the field. Accommodation will be organized by the postholder in Sudbury, a vibrant city of 150,000 people, where they will be primarily based.

The postholder will possess a biological subject qualification to A-level standard at a minimum. They should have some experience sampling water quality, practical knowledge of both lab and field equipment, basic data management skills, and some ability to identify aquatic organisms. Experience working for extended periods in remote locations often under physically challenging conditions (i.e. cold and wet) is highly desirable. The postholder should also be comfortable on the open water, and possess or be willing to acquire first aid and other safety training.

Fixed-term: The funds for this post are available for 30 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should provide a CV, the filename of which should be "CV-followed by your name", including contact details of two or more referees, and a covering letter addressing the selection criteria.

For further information contact Dr Andrew Tanentzap (ajt65@cam.ac.uk)

Please quote reference PD05510 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Software Developer (Fixed Term)

From Jobs at the University of Cambridge. Published on Feb 27, 2015.

Applications are invited for a software developer to work on InterMine (intermine.org), an open-source data mining project based in the Cambridge Systems Biology Centre at the University of Cambridge. This role will involve creating new features for the InterMine data warehouse platform as part of an exciting synthetic biology project that aims to enable the end-to-end design, construction and validation of large DNA constructs for academic and industrial application supporting a wide range of fundamental and biotechnology related research in the UK and beyond.

The successful applicant will help create tools to query and display complex biological data.

InterMine is a JVM-based application with a PostgreSQL datastore and interfaces written in HTML5 and JavaScript. Specific technologies we use include: Java, Clojure, Python, Angular, React, Backbone and others where appropriate. We care about RESTful services and open standards. We are designing a next generation interface to complex data for the modern web.

Applicants should have experience and interest in some of these technologies, and a background in open source software would be advantageous. Some knowledge of biology would be helpful. Previous experience with source control software, unit testing and build tools is required.

Informal enquiries should be directed to Julie Sullivan (j.sullivan@gen.cam.ac.uk).

Fixed-term: The funds for this post are available until 15 February 2016 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that in the Upload section of the online application you upload your Curriculum Vitae (CV) and a covering letter, explaining why you are suited to the position.

Please quote reference PC05507 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Software Developer / Bioinformatician (Fixed Term)

From Jobs at the University of Cambridge. Published on Feb 27, 2015.

Applications are invited for a software developer to work on InterMine (intermine.org), an open-source data mining project based in the Cambridge Systems Biology Centre at the University of Cambridge. This role will involve creating new features for the InterMine data warehouse platform as part of an exciting project. The successful applicant will be part of a UK consortium that is developing new methods for the emerging field of Synthetic Biology and will be responsible for maintaining the current synthetic biology InterMine, adding new data, tools and features as required.

InterMine is a JVM-based application with a PostgreSQL datastore and interfaces written in HTML5 and JavaScript. Specific technologies we use include: Java, Python, Tomcat, Lucene, Git and Travis. We care about RESTful services and open standards. We are designing a next generation interface to complex data for the modern web.

Applicants should have experience and interest in some of these technologies, and a background in open source software would be advantageous. Knowledge of and interest in synthetic biology and/or bioinformatics would be an advantage. Previous experience with source control software, unit testing and build tools is required.

Informal enquiries should be directed to Julie Sullivan (j.sullivan@gen.cam.ac.uk).

Fixed-term: The funds for this post are available until 30 June 2017 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that in the Upload section of the online application you upload your Curriculum Vitae (CV) and a covering letter, explaining why you are suited to the position.

Please quote reference PC05506 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Laboratory Research Technician (Fixed Term)

From Jobs at the University of Cambridge. Published on Feb 27, 2015.

The Department of Plant Sciences is seeking to appoint a Research Laboratory Technician to carry out experimental work under the supervision of Prof Alex Webb. The successful candidate will be involved in generation of new Arabidopsis lines by introduction of reporter genes into transformation or crossing.

The role will require ability to set up experiments under minimal supervision with due care and attention. Day to day tasks will include testing and maintenance of the Arabidopsis lines, phenotyping of mutants, designing experimental approaches, recording data and RNA sequencing. The successful candidate will be responsible for following and ensuring strict safety procedures and safety checks.

The ideal candidate will have an A-Level or equivalent in a biological subject with experience in academic or commercial molecular biology, genetics and microbiology laboratories. It is important that the successful applicant has communication and interpersonal skills at a level that allows clear understanding between all group members and role holder of requirements and potential problems.

More information about the Webb lab is available here http://www.plantsci.cam.ac.uk/research/alexwebb

Fixed-term: The funds for this post are available until 2 November 2017 in the first instance. We wish the successful applicant to start in April 2015.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For further information contact Prof Alex Webb (aarw2@cam.ac.uk)

Please quote reference PD05504 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Glasswasher/Cleaner (Part Time)

From Jobs at the University of Cambridge. Published on Feb 27, 2015.

You will work as part of a team of cleaners providing a glass washing service and cleaning of a high standard in a large, friendly Department. The role will include washing of scientific glassware, cleaning research and teaching laboratories, lecture theatres, offices, corridors, stairways and toilets.

No formal qualifications are required although cleaning experience would be advantageous, as would experience of laboratory cleaning.

You should have a good level of oral communication skills with the ability to understand and follow written and verbal instructions including safety instructions regarding the use of cleaning chemicals. A willingness to be flexible in approach and reliability are essential.

Hours of work are 32 per week.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For informal queries please contact Phil Garrett, email pg101@cam.ac.uk, 01223 333764.

Closing date is midnight on Sunday 15 March 2015.

Please quote reference PM05502 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Data Technician (Fixed Term)

From Jobs at the University of Cambridge. Published on Feb 26, 2015.

Cambridge Centre for Proteomics (CCP) is currently looking to recruit a Research Data Technician within its core facility unit. The core facility offers proteomics services to users from the University of Cambridge and other worldwide academic and industrial groups.

The successful candidate will be required to analyse proteomics data using standard proteomic packages including Proteome Discoverer, Mascot and Scaffold and apply common statistical methods to datasets. Some degree of programming literacy is essential, preferably R/Bioconductor. The role-holder will be an integral member of CCP and will need to interact closely with other members of CCP and internal and external users of the service to provide interpretation of results from complex datasets.

The successful candidate will have a first degree in computer or biological sciences or statistics and previous experience in working with high throughput mass spectrometry data sets would be advantageous.

Fixed-term: The funds for this post are available for 2 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For all inquiries, please contact Mike Deery, md289@cam.ac.uk.

Please quote reference PH05266 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Accounts Administrator

From Jobs at the University of Cambridge. Published on Feb 26, 2015.

We are looking for a self directed and motivated individual to take joint responsibility with the Research Grants Administrator for the operational management of the Accounts office in PDN. PDN has an annual spend of £14m, split equally between departmental accounts and research grants. The successful candidate will oversee the department accounts (excluding research grants) and manage two accounts staff. You will take responsibility for the delivery of all operational activities including overseeing the processing of all financial transactions and monitoring budgets.

The successful candidate will be a team player with strong management and communication skills (both oral and written), enjoy problem solving, be able to prioritise effectively and work to tight deadlines. An excellent knowledge of the University's Oracle finance system will be critical and you should be AAT qualified (or equivalent).

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Closing date: midnight on Sunday 15 March 2015. Interviews will be held on Monday 30 March 2015.

Please quote reference PM05490 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Programmer and Laboratory Manager

From Jobs at the University of Cambridge. Published on Feb 23, 2015.

A Programmer and Laboratory Manager is sought to support the Adaptive Brain Laboratory at the University of Cambridge.

The role involves facilitating the work of the research team by providing computing and technical support for around 15 individuals. The post also involves facilitating interactions within a network of top European research laboratories (www.adaptivebrain.eu).

Applicants should have a degree in a science or engineering subject and have significant experience in maintaining networked PCs and writing computer code. Excellent organization skills, the ability to provide training and support to others, and the ability to maintain strong local and international working relationships are essential.

Fixed-term: The funds for this post are available for 12 months in the first instance.

Further information may be downloaded below.

Informal enquiries about this position may be sent to Professor Zoe Kourtzi, zk240@cam.ac.uk

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

If you do not hear from us within 4 weeks of the closing date please assume your application has been unsuccessful.

Please quote reference PJ05458 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Feb 18, 2015.

A postdoctoral research associate position is available for up to twelve months to work in the laboratory of Dr A.P. Jackson, University of Cambridge, Department of Biochemistry, Tennis Court Road, Cambridge. The project will study the role of sodium channel ß-subunits in the structure and assembly of the pain-sensing sodium channel Nav 1.7, and its potential for drug targeting.

We are looking for an experienced structural biologist, ideally with some background in ion channel structure and a familiarity with general molecular biological methods. The work is a collaborative project between Dr A.P. Jackson, Dr DY Chirgadze (Dept. Biochemistry), Prof. C-L. Huang (Dept. Physiology, Development and Neuroscience) and the Antibody Discovery and Protein Engineering Department, MedImmune. It builds on recent evidence that some ß-subunits can cross-link sodium channels together on the neuronal plasma membrane (see: Namadurai et al., Open Biol. 2015 5:140192. DOI: 10.1098/rsob.140192). The basis of this cross-linking, and the role of ß-subunits in modulating drug binding will be investigated using structural and functional methods.

Skills required in tissue culture and basic molecular biology, experience with X-ray crystallography would be an advantage.

Applicants should have a PhD or the equivalent in a relevant science.

The University values diversity and is committed to equality of opportunity.

Fixed-term: The funds for this post are available for up to 12 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For all informal inquiries, please contact Dr A.P. Jackson - apj10@cam.ac.uk

Please quote reference PH05392 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate - Lysosomal Membrane Fusion (fixed term)

From Jobs at the University of Cambridge. Published on Feb 17, 2015.

Applications are invited for a Research Assistant/Associate (fixed term) to investigate the molecular basis of lysosomal membrane fusion. The successful applicant will join a multidisciplinary team that aims to define, at atomic resolution, how cells regulate the docking and fusion of lysosomes with organelles such as late endosomes or autophagosomes. Understanding this process will help us understand a range of processes important for health, from processing of peptides implicated in neurodegeneration to infection of cells by Ebola virus.

The post will be held at the Department of Pathology in the laboratory of Dr Stephen Graham, located on the Cambridge Biomedical Campus. Candidates should have a PhD, or expect to obtain one shortly, and should have a strong background in cell biology and biochemistry. Prior experience in eukaryotic membrane trafficking, quantitative mass spectrometry (SILAC, iTRAQ and/or proximity-based biotinylation), and immunofluorescence microscopy would be advantageous. This post would be ideal for a skilled biochemist/cell biologist looking to obtain experience in protein chemistry, biophysics and/or structural biology.

The ability to work both independently and as part of a team, coupled with excellent communication, organizational and problem solving skills are required. The duties/responsibilities of this post include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures as outlined on the Further Information Document.

Fixed-term: The funds for this post are available immediately for 18 months or until 31/12/2016 in the first instance.

The closing date for all applications is Thursday 19th March, 2015 and interviews will be held on Friday 27th March.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05435 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate - Bioinformatician

From Jobs at the University of Cambridge. Published on Feb 16, 2015.

Applications are invited for a two-year Research Associate - Bioinformatician position based at the Addenbrooke's Hospital site in Cambridge, jointly funded by Departments of Pathology (a grant award from Kay Kendall Leukaemia Fund) and Medical Genetics, University of Cambridge, between 1 April 2015 and 31 March 2017.

The successful candidate will develop and implement bioinformatic tools to analyze next generation sequencing (exome, targeted resequencing, CHIP-Seq) and large scale genotyping data from cancer and germline genetic studies in the research laboratories of Professor Ming-Qing Du (Pathology) and Professor Eamonn Maher (Medical Genetics). Applicants should have a PhD in a relevant subject, an excellent knowledge of a programming or scripting language, and significant experience in bioinformatic analyses, ideally in next generation sequencing data analyses. The post-holder will work closely with other bioinformaticians in the Biomedical Research Centre, should be highly motivated, and have the ability to plan and conduct high quality bioinformatic analyses within a multidisciplinary team.

The ability to work both as part of a team, and independently, coupled with excellent communication, organizational and problem solving skills are required. The duties/responsibilities of this post include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures as outlined in the Research Associate Further Information document.

Further information about the research group can be found at the group's website (http://www.path.cam.ac.uk/pages/du/; http://medgen.medschl.cam.ac.uk/professor-eamonn-maher/research-profile/). Informal enquires may be made to Professor Ming-Qing Du (mailto:mqd20@cam.ac.uk)

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05408 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Human Resources Administrator

From Jobs at the University of Cambridge. Published on Feb 16, 2015.

University of Cambridge Department of Veterinary Medicine West Cambridge Site

We wish to appoint an HR Administrator from 1 May 2015 or as soon as possible after that date. The role will work closely with other team members to cover all administrative aspects of HR in the Department, in accordance with good HR practice, in order to provide an efficient and effective service to PIs and line managers in the Department. This includes recruitment; payroll; undertaking specific projects, in particular those relating to the Department's Athena SWAN initiatives; and administering periodic and annual exercises which also underpin Athena SWAN. The role holder is responsible for providing advice to managers and other staff in areas that fall within the remit of this role, in line with the University's policies and procedures.

The following are essential:

  • education to A level standard
  • a basic knowledge of employment law and principles of best practice HR
  • strong IT skills including Word, Excel, Powerpoint and Outlook, and ability to use and grasp new technologies
  • excellent communication and interpersonal skills with the ability to deliver the highest level of customer service to job applicants
  • ability to empathise with staff, to deliver the highest level of customer service, and use tact, discretion and diplomacy
  • several years' experience of working in an administrative role in an HR environment
  • ability to prioritise workload to meet multiple deadlines, forward plan and manage a number of task effectively and at the same time
  • ability to work independently with little supervision and to manage own workload
  • accuracy and attention to detail, ability to maintain this under pressure
  • experience of working effectively as part of a team
  • excellent written and spoken English
  • excellent administrative and organisational skills
  • excellent note taking skills
  • proactive and ability to use initiative
  • ability to maintain confidentiality

The following are desirable:

  • education to degree level
  • hold or working towards CIPD qualification
  • knowledge of University HR systems (RAS, Web Recruitment, CHRIS) desirable

Closing date for applications: 9 March 2015

Interview date: 26 March 2015

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Department website: www.vet.cam.ac.uk Further information about the role: click on link below To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not done so already) and log in before completing the online application form.

Please quote reference PP05413 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Senior Clinical Training Scholarships in Small Animal Medicine (Two Scholarships, one funded by Alice Noakes Trust)

From Jobs at the University of Cambridge. Published on Feb 16, 2015.

UNIVERSITY OF CAMBRIDGE DEPARTMENT OF VETERINARY MEDICINE

TO START 1 JULY 2015 AND 1 AUGUST 2015

SCHOLARSHIP AWARD £21,390.00 (Year one)

Two Scholarships are available, to start on 1 July and 1 August 2015. The Scholarship provides an outstanding opportunity to study for a postgraduate qualification. The training programme covers all aspects of small animal medicine, including clinical nutrition, oncology and clinical pathology, and is approved by the European College of Veterinary Medicine.

The Scholarship is for one year in the first instance, renewable for periods of one year up to a total of three years. It is subject to an initial monitoring period of six months, and review on an annual basis.

The Scholar will be required to register for a Diploma in the appropriate field. The training programme requires participation in the Department's clinical service, including the out-of-hours rota and first opinion practice, in addition to small-group teaching of veterinary students.

An applicant must be a Member of the Royal College of Veterinary Surgeons, or hold a veterinary degree qualifying her/him for membership. Completion of a recognised internship or a minimum of two years' experience in small animal practice is essential.

Informal enquiries: contact Professor Michael Herrtage on mh10001@cam.ac.uk

Closing Date: 8th March 2015

Interview date: 26th March 2015

Fixed-term: 3 years.

Application form (SCTS1) and information pack: download from link below

Completed application form, curriculum vitae, covering letter: send to Melissa Large, Department of Veterinary Medicine, Madingley Road, Cambridge, CB3 OES, or email to vetmed@hermes.cam.ac.uk

Please quote reference PP05417 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Post-doctoral Research Associate/Research Assistant (Fixed Term)

From Jobs at the University of Cambridge. Published on Feb 16, 2015.

Applications are invited for a Post-doctoral Research Associate/Research Assistant position in the Department of Psychology at the University of Cambridge.

This 18-month project will examine decision-making in adults with Autism Spectrum Conditions (ASCs). The research will focus on how people make choices between options which differ on multiple dimensions (e.g., two products differing in quality and price).

You will use a combination of behavioural tasks, eye-tracking, and mathematical modelling to establish how people sample and integrate information about competing options in order to produce a decision, and how these processes differ in individuals with ASCs.

The post-holder must have a PhD in Psychology or a closely related discipline (Research Associate) or be in the process of submitting their thesis (Research Assistant) and have demonstrable experience of conducting, analyzing, and interpreting behavioural studies of human decision-making. This should include working independently to programme experimental tasks, recruiting and running heterogeneous participant samples, and using a range of statistical techniques for data analysis. Previous experience of eye-tracking will be very advantageous, as will practical experience of mathematically modelling experimental data; familiarity with research into ASCs would also be helpful. The salary range if appointed as a Research Associate is £28,695 - £37,394 per annum and the salary range if appointed as a Research Assistant is £24,775 - £28,695 per annum.

Further information may be downloaded below.

Informal enquires should be directed to Dr William Matthews, email: wjm22@cam.ac.uk

Fixed-term: The funds for this post are available for 18 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo an enhanced Disclosure and Barring Service check.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

If you do not hear from us within 4 weeks of the closing date please assume your application has been unsuccessful.

Please quote reference PJ05396 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate - Cell Biology of Infection

From Jobs at the University of Cambridge. Published on Feb 13, 2015.

Applications are invited for a 3-year Post-doctoral Research Associate (fixed term) funded by the Medical Research Council to work on the host cell biology underlying typhoid disease. Salmonella pose a major global health threat. Understanding the cell biology of disease is crucial to develop new anti-infectives and combat infectious disease.

The successful applicant will join Dr. Daniel Humphreys at the Department of Pathology located in central Cambridge to address the cellular mechanisms by which the typhoid pathogen Salmonella Typhi reprogrammes human cell biology to establish intracellular infection, and why it fails to do so in non-human animal cells.

The project involves a multidisciplinary approach involving pathogen genomics, primary cell culture and cultured cell engineering, fluorescence imaging and manipulation of infected cells, and innovative biochemical reconstitution approaches. The applicant will work in a collaborative environment, interacting with Prof. Vassilis Koronakis at the Department of Pathology and Prof. Gordon Dougan at the Wellcome Trust Sanger Institute.

Applicants must have or be about to receive a relevant PhD and have a good track record in this field. An interest in membrane trafficking and the cytoskeleton, as well as experience of fluorescence microscopy, infection, molecular genetics and cell culture is desirable. The ability to work both as part of a team, and independently, coupled with excellent communication, organizational and problem solving skills are required. The duties/responsibilities of this post include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures.

Fixed-term: The funds for this post are available immediately for 36 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05384 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (RNA biology: non-coding RNA and DNA methylation)

From Jobs at the University of Cambridge. Published on Feb 10, 2015.

Applications are invited for a postdoctoral researcher in the laboratory of Professor Eric Miska. We are looking for an outstanding individual to lead a research project which will help us solve key problems regarding the role of non-coding RNAs in genome stability and transgenerational epigenetic inheritance. In addition, this post will offer the opportunity to work on collaborative projects with other group members. We are particularly interested in applicants with prior experience in human cell culture, molecular biology, RNA biology, cell biology and computational biology. Expertise in DNA methylation, biochemistry, and mouse husbandry for this post is essential. For more information about the group, please visit: http://www.ericmiskalab.org.

Limited funding: The funds for this post are available for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PR05346 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Research Associate (RNA proteomic approaches)

From Jobs at the University of Cambridge. Published on Feb 10, 2015.

Applications are invited for a postdoctoral researcher in the laboratory of Professor Eric Miska. We are looking for an outstanding individual to lead a research project which will help us solve key problems regarding the role of non-coding RNAs in genome stability and transgenerational epigenetic inheritance. In addition, this post will offer the opportunity to work on collaborative projects with other group members. We are particularly interested in applicants with prior experience in human cell culture, molecular biology, RNA biology, cell biology and computational biology. Experience in cancer biology, cell signalling, proteomics and post-translational modification, eg phosphorylation, is essential.

For more information about the group, please visit: http://www.ericmiskalab.org.

Limited funding: The funds for this post are available for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PR05345 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Research Career Development Fellow

From Jobs at the University of Cambridge. Published on Feb 09, 2015.

Applications are invited for Research Career Development Fellowships in the Sainsbury Laboratory. The positions are open to applicants of any nationality. With the intention of nurturing the next generation of researchers in the field of plant science, the Fellowships provide an opportunity for talented junior investigators to develop their own research programme and become creative leaders in the field.

The Sainsbury Laboratory is a new Research Institute located in central Cambridge, providing an outstanding scientific environment. It has excellent resources and core facilities, with state-of-the-art equipment including growth rooms, glasshouses, microscopy and computing facilities. It provides a collaborative research atmosphere where researchers can take risks in a supportive environment. We are seeking to appoint Career Development Fellows who can both contribute to and benefit from this environment. In particular we are looking for scientists with imaginative research ideas that will contribute to our understanding of plant development, by elucidating the links between genotype and phenotype in any appropriate study system.

Applicants will typically have between 3 and 6 years of postdoctoral experience in a field related to the overall scientific focus of the Laboratory in plant development and its computational modelling. Applicants should be able to provide strong evidence of their potential to develop independent research programmes.

Fellowships are for five years. Successful applicants will receive an initial three years of funding, with extension for a further two years contingent on a successful scientific review and will hold an appointment with the University of Cambridge. Funds include full salary, ranging from £38,511 to £48,743, an additional 30% Gatsby distinction award, benefits and £40,000 p.a. of unrestricted research support. As they develop into independent researchers, Fellows will be encouraged to apply for external funding. Fellows can apply for Research Group Leader positions within the Laboratory at any time.

Further details about the post, guidance on how to apply and information about the Sainsbury Laboratory are available on the Sainsbury Laboratory web site: http://www.slcu.cam.ac.uk/

Applications can be submitted electronically at any time as a single pdf file including a full CV, a research proposal for five years, and the names of at least three referees. Completed applications should be sent by e-mail to enquiries@slcu.cam.ac.uk.

Fixed-term: The funds for this post are available for 5 years.

There is no fixed closing date- applications will be assessed throughout the year.

Please quote reference PT05330 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Career Development Fellow - Computational Modelling of Developmental Systems

From Jobs at the University of Cambridge. Published on Feb 09, 2015.

Applications are invited for Research Career Development Fellowships in the Sainsbury Laboratory. The positions are open to applicants of any nationality. With the intention of nurturing the next generation of interdisciplinary researchers in the field of plant developmental biology, the Fellowships provide an opportunity for talented junior investigators to develop their own research program and become creative leaders in the field. The Sainsbury Laboratory is a new Research Institute, providing an outstanding scientific environment. It has excellent resources and core facilities, with state-of-the-art equipment including high performance computing, growth rooms, glasshouses and microscopy. It provides a collaborative research atmosphere where researchers can take risks in a supportive environment. We are seeking to appoint Career Development Fellows who can both contribute to and benefit from this environment. In particular we are looking for scientists with computational or mathematical modeling expertise and imaginative research ideas that will contribute to our understanding of plant development by elucidating the links between genotype and phenotype. Experience with plant systems is not required. Applications are welcome from researchers wishing to move into plant biology from any other study system.

Applicants will typically have between 3 and 6 years of postdoctoral experience and should be able to provide strong evidence of their potential to develop independent research programs. Fellowships are for five years. Successful applicants will receive an initial three years of funding, with extension for a further two years contingent on a successful scientific review and will hold an appointment with the University of Cambridge. Funds include full salary, ranging from £38,511 to £48,743, an additional 30% Gatsby distinction award, benefits and £40,000 p.a. of unrestricted research support. As they develop into independent researchers, Fellows will be encouraged to apply for external funding. Fellows can apply for Research Group Leader positions within the Laboratory at any time.

Further details about the post, guidance on how to apply and information about the Sainsbury Laboratory are available on the Sainsbury Laboratory web site: http://www.slcu.cam.ac.uk/

Applications can be submitted electronically at any time as a single pdf file including a full CV, a research proposal for five years, and the names of at least three referees. Completed applications should be sent by e-mail to enquiries@slcu.cam.ac.uk.

Fixed-term: The funds for this post are available for 5 years.

There is no fixed closing date - applications will be assessed throughout the year.

Please quote reference PT05341 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Business and Operations Manager

From Jobs at the University of Cambridge. Published on Feb 09, 2015.

The University of Cambridge offers the best of all academic worlds - a tradition of excellence and a clear agenda for continuous development. Our legacy of life-changing research and innovation keeps us at the cutting-edge, and stem cell biology and regenerative medicine is one such area where we excel. This is your chance to use your management expertise to contribute to the success of a new dynamic, world-leading institute: the Stem Cell Institute.

You will play a key part in the effective and efficient delivery of our research vision as you lead our administrative and facility teams. We'll look to you to service committees while developing management systems and delivering change initiatives. HR processes, reporting and supporting funding applications will all fall within your remit. Your main challenge will be driving the relocation of all 25 groups into a new state-of-the-art building at the Cambridge Biomedical Campus in 2018.

You will be outstanding in staff management, both leading teams and building consensus. Your considerable experience of managing HR and finance functions, ideally within a University environment, will be matched by an understanding of scientific working environments. Above all, you will have an aptitude for finding solutions to both practical and strategic challenges that will ensure the operational success of the Institute.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Sunday 15th March 2015.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Interviews will be held on Tuesday 31st March 2015. If you have not been invited for interview by 27th March 2015, you have not been successful on this occasion.

Please quote reference PS04037 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate - Bioinformatician (Fixed Term)

From Jobs at the University of Cambridge. Published on Feb 09, 2015.

Fixed-term: The funds for this post are available until 31 January 2018 in the first instance.

The Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute (SCI) comprises 200 researchers spanning fundamental science through to clinical applications. Our goal is to advance disease modelling, drug discovery and regenerative medicine through understanding the genetic and biochemical mechanisms that control stem cell fate.

Applications are invited for a computational biologist to join the research group of Dr Paul Bertone at the Wellcome Trust - Medical Research Council Stem Cell Institute at the University of Cambridge. We apply state-of-the-art experimental and computational methods toward understanding the biological properties and biomedical potential of stem cells.

The project will bridge the research groups of Dr Paul Bertone and Dr Michaela Frye, and will focus on elucidating the role of RNA methylation in regulating protein translation and regulating stem cell fate. Experimental data will be drawn from human ES and neural stem cell culture, genome editing techniques, in vitro viral infections, RNA-seq, miCLIP, ribosome profiling, histology, imaging and flow cytometry. This arrangement provides an excellent environment for research and career development, as the post holder will benefit from the resources and expertise of both experimental and computational laboratories to lead this multidisciplinary project.

The successful candidate will be required to communicate effectively with experimentalists and organize collaborative projects. The post holder will have the opportunity to initiate their own computational projects, but will also coordinate with colleagues in the Frye lab and contribute to the design and execution of related studies. He or she will have a strong publication record and enjoy working on ambitious projects at the frontiers of genomics and biotechnology. Projects will apply large-scale gene expression profiling, comparative genomics and regulatory systems modelling. The study will make use of neural stem cells as an experimental platform, and therefore knowledge of neural development would be beneficial.

Candidates will have a solid background in computation and current knowledge of eukaryotic genomics. Expertise in statistical methods and Unix scripting are essential. Additional experience with high-throughput sequencing data, numerical computing or regulatory systems modelling is desirable but not required. Applicants should hold a PhD in a relevant field (e.g. Bioinformatics, Applied Mathematics, Computer Science, Biomedical Engineering, or Neuroscience/Biochemistry/Molecular Biology with a computational component).

Previous experience in stem cell biology is not necessary. Start date is flexible but can be as early as May 2015.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Monday 23rd March 2015.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Interviews will be held 1-3 April 2015. If you have not been invited for interview by 30th March 2015, you have not been successful on this occasion.

Please quote reference PS05338 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Drosophila Literature Analyst Research Assistant/Associate (Part Time, Fixed Term)

From Jobs at the University of Cambridge. Published on Feb 06, 2015.

FlyBase (flybase.org) seeks a part-time (50-75%) literature analyst to join our group at the University of Cambridge, UK (www.gen.cam.ac.uk/research/flybase.html). This is an office-based post away from the bench, assisting fruit fly (Drosophila) research by contributing to the FlyBase database of genetic and genomic data.

The primary aim of FlyBase-Cambridge is to identify biological data from scientific articles concerning Drosophila and to record these data in a systematic manner. Curated data are subsequently integrated into the FlyBase database and website to aid the international research community. The successful applicant will contribute to this effort in one or more ways, depending on their expertise. Possible roles include: rapid reading of Drosophila review articles to record genes mentioned therein; recording information about Drosophila models of human disease; focused analysis and annotation of sets of related genes: or contributing to revisions of existing data in the database.

Essential skills/experience include: a biological sciences degree, research experience using Drosophila, strong organizational skills and the ability to work with attention to detail. Applicants must also have good communication skills, including excellent English and strong self-motivation as well as the ability to work in a team.

Useful skills/experience include: familiarity with databases, programming, annotation/curation experience.

Informal enquiries to Dr. Steven Marygold - sjm41@gen.cam.ac.uk.

Fixed-term: The funds for this post are available until 31 March 2016 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that in the Upload section of the online application you upload your Curriculum Vitae (CV) and a covering letter, explaining why you are suited to the position.

Please quote reference PC05326 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Feb 03, 2015.

We are seeking a Research Associate to work on a project investigating biases in adults' Theory of Mind funded by the ESRC. The Principal Investigator (PI) is Professor Nicola Clayton and the Co-Investigator is Professor Robert Lurz.

The person appointed will primarily be responsible for the designing, programming and running of experiments. These experiments will seek to test the nature and the extent of adults' ability to reason about what others see and believe as well as the causes of any biases adults show in such tasks. This work will involve ensuring that the experiments meet ethical guidelines, recruiting and testing participants as well as data collection and analysis. Where appropriate the post holder will be responsible for writing and publishing manuscripts relating to these experiments and communicating their results at academic conferences. The post holder will also be required to organise and run public engagement activities closely related to the research outcomes. In addition, the post holder will be required to liaise with the PI and Co-Investigator to ensure that the research being undertaken is appropriate and that the conditions of the grant are met. The post holder will also be required, where necessary, to supervise undergraduate and graduate students, research assistants and visiting researchers.

The post holder must have a PhD in Experimental Psychology or a closely related discipline. The post holder should be capable of working in an international multi-disciplinary team. They are expected to have extensive experience of designing and running experiments on social cognition (preferably testing adults). The post holder should be able to code experiments using appropriate software and to analyse data using appropriate statistical techniques. Knowledge of the literature on adult Theory of Mind is essential and on comparative cognition and philosophical approaches to testing Theory of Mind is desirable.

Further information may be downloaded below.

Informal enquiries about this post may be directed to Professor Nicola Clayton (nsc22@cam.ac.uk).

Fixed-term: The post will start from 1 May 2015 and funds for this post are available for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

If you do not hear from us within 4 weeks of the closing date please assume your application has been unsuccessful.

Please quote reference PJ05291 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate - The Behavioural Ecology Group (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 28, 2015.

This position, based in central Cambridge at the Department of Zoology, University of Cambridge, is available for up to 28 months with a start date of 1 July 2015 to work with Prof Rebecca Kilner and her team. The project is funded by a European Research Council grant and will investigate whether parental care can drive evolutionary change.

Website nicrophorus.zoo.cam.ac.uk

Duties will include: Running a large-scale selection experiment Running or supervising complementary experiments in the lab or field Assisting in monitoring of beetle numbers at local field sites Collection and analysis of microsatellite data (or similar) Data collection, analysis and interpretation Preparation of manuscripts for publication

KNOWLEDGE, SKILLS AND EXPERIENCE FOR THE ROLE

Essential: A PhD in evolutionary ecology or behavioural ecology or entomology or closely related subjects Background knowledge (e.g. from degree course) of research methods and theory in behavioural ecology and evolutionary biology Ability to organise time, plan ahead and to work effectively independently. Good data handling and data analysis skills. Good communication skills (written and oral). Ability to work in a team and strong inter-personal skills.

Desirable: Some post-doctoral experience Any relevant laboratory experience, particularly in carrying out selection experiments or experimental evolution Experience in collecting and analysing microsatellite data (or similar) Experience of fieldwork with insects. Background knowledge (e.g. from degree course) of entomology or microbiology Interest in natural history. Some experience of managing others.

Deadline: 5pm Thursday 5 March 2015

Interview date: during week beginning 23 March 2015

Fixed-term: The funds for this post are available for up to 28 months.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PF05243 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Senior Clinical Training Scholarship in Anaesthesia

From Jobs at the University of Cambridge. Published on Jan 27, 2015.

UNIVERSITY OF CAMBRIDGE DEPARTMENT OF VETERINARY MEDICINE THE QUEEN'S VETERINARY SCHOOL HOSPITAL

Start Date 3 August 2015

Scholarship award: £21,390.00 in year one.

The Scholarship is for one year in the first instance, renewable for periods of one year up to a total of three years.

The Scholarship provides an outstanding opportunity to receive specialist training in all aspects of veterinary anaesthesia. You will be required to register for a post-graduate qualification by enrolling onto the European Diploma in Veterinary Anaesthesia and Analgesia.

You will receive core training in all aspects of academic and clinical anaesthesia, pain management and peri-operative medicine (including critical care) in both small and large animals at the Queen's Veterinary School Hospital. You will also be required to undertake and publish a research project, and participate in the small-group teaching of veterinary students. The training programme is approved by the European College of Veterinary Anaesthesia and Analgesia.

You must be a Member of the Royal College of Veterinary Surgeons, or hold a veterinary degree qualifying you for membership. Membership will be required prior to commencing the Scholarship. A minimum of twelve months experience in a rotating internship or at least two years' experience in general practice is essential.

Informal discussion: contact Dr Jackie Brearley, jcb78@cam.ac.uk or Matthew McMillan mwm32@cam.ac.uk

Closing date: 8 March 2015

Interview date: 24 March 2015

Application form (SCTS1) and information pack about the Scholarship: download from link below.

Completed application form, curriculum vitae, covering letter: email vetmed@hermes.cam.ac.uk by closing date.

Please quote reference PP05229 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

BBSRC PhD Studentship

From Jobs at the University of Cambridge. Published on Jan 05, 2015.

A BBSRC PhD studentship fully funded for four years is available in the laboratory of Professor Paul Dupree. The project is in partnership with Novozymes, the world's largest enzyme discovery and production company.

The industrial collaborative project aims to develop tools and understanding with application to the bioenergy, biorefining and dietary uses of plants. The project goal is to understand the role of the plant cell wall polysaccharide xylan in preventing enzymatic digestion of cellulose microfibrils. Our recent discoveries propose new models for xylan interaction with cellulose (Busse Wicher et al. 2014). The new models suggest new types of enzymes may be involved in plant cell wall deconstruction. The project will use the extensive range of specific recombinant hydrolases and polysaccharide oxidases (e.g. cellulases, xylanases, LPMOs) available from Novozymes, and also the extensive panel of plants with modified plant cell wall synthesis available in the laboratory of Paul Dupree.

The student will spend at least three months in Novozymes, Copenhagen, gaining experience of industrial enzyme discovery and development.

The project will start during the 2015-2016 academic year.

Busse-Wicher M et al. (2014) The pattern of xylan acetylation suggests xylan may interact with cellulose microfibrils as a two-fold helical screw in the secondary plant cell wall of Arabidopsis thaliana. Plant J. 79(3):492-506.

Please contact Professor Paul Dupree - pd101@cam.ac.uk for any enquiries.

BBSRC studentship eligibility conditions apply.

http://www.bioenergy.novozymes.com

Please quote reference PH04924 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.