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BBSRC Doctoral Training Partnership Administrator (Secondment opportunity for internal candidates only, 0.6FTE)

From Jobs at the University of Cambridge. Published on Apr 01, 2015.

We are seeking a highly-organised and motivated person to manage the administration of a BBSRC-funded Doctoral Training Partnership.

The Administrator will co-ordinate activities relating to 4-year PhD programmes which include a 3-month internship for each student. The Partnership is a collaboration between six Cambridge University institutions and five external institutes. You will liaise between the different partners, located at several sites in and around Cambridge.

You will act as the first point of contact for a range of staff and student queries. Main responsibilities include management of the admissions and registration processes; supporting delivery of teaching and co-ordination of assessment; acting as Secretary to the Executive Groups; monitoring income and compiling financial reports; organising a thesis focus day.

You will have at least an A-Level standard of education, together with some knowledge and experience of the UK HE sector. You will be an excellent communicator, able to liaise effectively with staff and students. Educational or research management experience would be advantageous.

The secondment runs from 27 April to 23 October 2015.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For further information contact Catherine Butler, Department Administrator (cek31@cam.ac.uk)

Please quote reference PD05790 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 31, 2015.

Studying sleep and EEG in transgenic mouse models of Huntington's disease:

We are seeking a Research Assistant to study sleep and EEG in mouse models of neurodegenerative diseases. You will join an interdisciplinary research team that is interested in understanding neurological dysfunction in Huntington's disease (HD). HD is an incurable neurodegenerative genetic disorder that causes progressive deterioration of motion and cognitive function, as well as changes in psychiatric domains such as anxiety and depression. Recently, sleep and EEG abnormalities have also been identified in both HD patients and mouse models of the disease. The purpose of this project is to develop objective measures for understanding the mechanisms underlying the pathological changes found in HD with a special focus on sleep and EEG. The results will contribute to a larger project led by Professor Jenny Morton studying the effects of neurodegeneration in HD and interventions to prevent progression of the disease. The results will also have broad relevance to fields of animal behaviour and cognitive and systems neuroscience.

You will be part of a research team investigating sleep-wake behaviour and EEG in normal and transgenic mouse models of HD. Training in the use of EEG/EMG recording systems will be given.

The successful applicant will be a careful and methodical worker who is self-motivated and able to conduct experiments and analyse data independently. Careful observation skills and accurate record keeping are essential. Applicants should hold a Home Office personal licence.

Applicants must have a BSc degree (or equivalent), preferably with a background in Neuroscience. Experience in analysing EEG traces or behavioural testing would be an advantage. Familiarity with data analysis software such as MatLab, Spike 2 or SleepSign is highly desirable. The post will require some weekend work and a flexible approach to working hours.

Fixed-term: The funds for this post are available for 18 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please upload your CV and a covering letter outlining your suitability for the post.

Please quote reference PM05791 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate - Structural Biology of membrane proteins (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 30, 2015.

A postdoctoral Research Associate position is available to work on the structural biology of mammalian membrane proteins using the latest technology in X-ray crystallography. The post is based in the laboratory of Dr Simone Weyand, University of Cambridge, Departmental of Biochemistry, Central Cambridge and is for 1 year initially.

The role involves the ideal candidate to carry out all the steps from cloning to structure determination of a human GPCR. The successful candidate will be highly motivated with a track record of working on integral membrane proteins and expertise in at least one, and preferably more, of the following areas: over-expression in insect or mammalian cells, membrane protein purification, and X-ray crystallography structure determination. Candidates must be self-motivated individuals who enjoy working as part of a collaborative and multidisciplinary team. Strong leadership, communication and teamwork skills are decided assets.

Candidates should hold a PhD or the equivalent in a relevant specialist subject.

Fixed-term: The funds for this post are available for 1 year in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For all informal enquiries please contact Dr Simone Weyand - sw644@cam.ac.uk

Please quote reference PH05779 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 27, 2015.

Post-doctoral endothelial cell biochemist.

A Post-doctoral Research Associate position is available to work on the regulation of vascular endothelial cell activity by sub-endothelial collagens. The post is based in University of Cambridge, Department of Biochemistry, Central Cambridge working in the laboratory of Professor Richard Farndale, and is funded by a British Heart Foundation Programme grant.

The successful applicant will be qualified in biochemistry and/or cell biology, and will have a strong interest in receptor biology. He or she will be fully trained in cell culture, and will preferably be skilled in vascular biology and the measurement of endothelial cell activity. The successful applicant will extract and maintain primary human endothelial cells, and will study their regulation by specific collagen receptors. Transcriptome will be measured using next generation RNAseq, and the RA will apply ligand proximity assays to the identification of novel receptors, then explore the signals elicited in the cells by specific collagen fragments selected from our Collagen Toolkits.

Candidates should have a PhD or the equivalent in a relevant science.

Interviews are anticipated during late April/early May.

Fixed-term: The funds for this post are available for 42 months until 30 November 2018 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For all informal enquiries please contact Professor Richard Farndale - rwf10@cam.ac.uk

Please quote reference PH05769 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant (Koo Lab) (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 27, 2015.

Fixed-term: The funds for this post are available for 2 years in the first instance.

The Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute is an international centre of excellence for research into stem cell biology and medicine. Scientists in the Institute collaborate to generate new knowledge and understanding of the biology of stem cells and provide the foundation for new medical treatments.

We are looking for a self-motivated, reliable and well-trained research assistant to join the research team of Dr. Bon-Kyoung Koo. His team will investigate a novel quiescent Troy+ epithelial stem cell population in the stomach. Upon tissue damage, Troy+ stem cells actively divide to regenerate lost cell types. The discovery of Troy+ stomach stem cells enables us to investigate how an adult tissue can retain its homeostasis after various types of injury. This study will help us to understand how homeostasis is achieved in the adult stomach and in other tissues, which will potentially lead to the development of successful adult stem cell therapy.

Requirements:

A Bachelor degree in a Bioscience related subject. A good knowledge in biochemistry, molecular biology and developmental biology. At least short-term lab experience. Previous experience in flow cytometry and confocal microscopy is preferred, but not essential. Ability to quickly learn and independently apply new techniques after induction. A proven capacity to understand and interpret research articles. Good communication skills in English. Highly independent, motivated, ambitious, and collaborative person.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Sunday 26th April 2015.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Informal enquiries about the post are also welcome via email on cscrjobs@cscr.cam.ac.uk.

Interviews will be held on Wednesday 6th May 2015. If you have not been invited for interview by 1st May 2015, you have not been successful on this occasion.

Please quote reference PS05642 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant x 3 (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 26, 2015.

We require three research assistants to pursue research in conjunction with many different projects in the University of Cambridge, Department of Biochemistry, Central Cambridge to work in the DNA Sequencing Facility. Candidates should be qualified to degree level in a relevant subject or the equivalent and have relevant experience as outlined below.

We are looking for research assistants to assist in the running of the DNA Sequencing Facility, which involves amongst other duties the processing of many thousands of samples which we receive on a regular basis. This requires concentration and good pipetting skills over an extended period. Other duties will include accounts processing, routine maintenance, operation of our equipment and record keeping.

The successful candidates will work in our Genome Sequencing Facility. Relevant experience with Roche 454 FLX and Junior platforms as well as Illumina MiSeq and NextSeq platforms is highly desirable . This will involve library preparation and a knowledge of bioinformatics which is essential.

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For all informal enquiries please contact John Lester - jbl21@cam.ac.uk

Please quote reference PH05712 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

University Lecturer in Virology

From Jobs at the University of Cambridge. Published on Mar 26, 2015.

The Department of Pathology is seeking to appoint a suitably qualified individual to a University Lectureship in Virology based in the Laboratory Block, Addenbrooke's Hospital (Cambridge Biomedical Campus). The post is to be filled as soon as possible. The post has tenure, subject to satisfactory performance in the first 5 years.

Applicants are expected to demonstrate excellence in research in any field of virology. The successful candidate will be educated to degree level, normally with a PhD in a relevant specialist subject area and have a strong publication record that is proportionate to their length of research experience. The potential to attract independent research funding is essential.

The person appointed will be expected to contribute to the Department's teaching, research, and administration, including membership of committees. Teaching duties may include giving lectures, demonstrating practical classes, supervising undergraduate and graduate research projects and examining.

In exceptional circumstances, it may be possible to offer a supplement to the salary range stated for this role of up to 10% of the lowest salary point for a maximum of five years. Any such supplement would be awarded on the basis of a demonstrable history of exceptional achievement and is entirely at the discretion of the University.

The deadline for applications is 5pm on Monday 27 April 2015. Short-listed candidates will be invited to visit the Department, to give a seminar on their work and meet prospective colleagues, prior to a meeting of the Appointments Committee. It is intended to arrange these visits week commencing 22 June 2015.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload a covering letter, your curriculum vitae (CV), a list of publications list, and a a one-page statement of research interests and future plans, as well as the names and addresses of three referees in the 'Upload' section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05704 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Cleaner (Part Time)

From Jobs at the University of Cambridge. Published on Mar 26, 2015.

Working in North Cambridge, you will be required to provide a high level of cleaning in all areas of the field station including offices, laboratories, indoor animal accommodation, communal areas and toilets. You will be required to work 18.25 hours per week.

No formal qualifications are required although an NVQ 1 Cleaning Methods qualification would be advantageous, as would experience of laboratory cleaning.

Good communication skills are essential along with the ability to follow written and verbal instructions from supervisors. A willingness to be flexible in approach and reliability are essential.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Closing Date: 12 April 2015

Please quote reference PM05758 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

University Lecturer

From Jobs at the University of Cambridge. Published on Mar 26, 2015.

Applications are invited for a research-oriented, tenure-track University Lectureship in Physiology, available from 1 November 2015 or as soon as possible thereafter. Based in central Cambridge, we are searching for an outstanding scientist, with an excellent publication record, undertaking cutting edge and fundable work in a field which complements our world class programme in physiology with a preference for comparative physiology or mammalian systems physiology research (http://www.pdn.cam.ac.uk/research/).

The successful applicant will have a PhD in a relevant subject area, will have an aptitude and enthusiasm for teaching, and be willing to contribute effectively to our undergraduate programmes in preclinical medicine, preclinical veterinary science, and natural sciences (http://www.pdn.cam.ac.uk/teaching). He/she will be expected to contribute to the design and delivery of undergraduate and graduate lecture courses and to perform other academic duties including administration, examining and assessment.

We welcome applications from all qualified candidates and we strongly encourage women to apply. Appointment will be based on merit alone.

Informal enquiries may be made to Professor Bill Harris, Head of Department (wah20@cam.ac.uk; +44 (0) 1223 766137/333772).

Appointment will be made at University Lecturer level with a probationary period of five years, with appointment to the retirement age thereafter. The pensionable salary scale starts at £38,511 to £48,743 per annum. Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment, with a satisfactory outcome determined by the University.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that, in the Upload section of the online application, you upload your Curriculum Vitae (CV), a research publication list which highlights your three most important published outputs, and a covering letter of no more than two pages, outlining current and future plans, indicating the fit within the research profile of the Department and how you might contribute to our teaching. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Closing Date: 30 June 2015

Please quote reference PM05747 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate

From Jobs at the University of Cambridge. Published on Mar 25, 2015.

Post-doctoral Research Associate positions are available to join Professor Julie Ahringer's laboratory to study the regulation of chromatin in development and gene expression using the C. elegans model system. Experimental and computational positions are available.

Our research programme uses the powerful model organism C. elegans for uncovering general principles of eukaryotic chromatin regulation, focusing on transcription regulation and genome organization in a developmental context. We are particularly interested in recruiting individuals to study the mechanism of action of enhancers and the formation and regulation of different types of chromatin domains. Our laboratory addresses these questions by applying high-throughput and directed methods to analyse gene expression and epigenetic state and function in wild-type and mutant animals and tissues.

Successful candidates will be motivated and organised individuals with a PhD in a relevant area, excellent verbal and written communication skills as evidenced by publications in internationally recognized peer-reviewed journals, and the ability to work both independently and as part of a team. Expertise in a broad range of molecular biology techniques or in bioinformatics/computational analyses are essential. Previous experience in investigating transcription, epigenetic control of gene expression, and/or computational analyses are desirable.

The Gurdon Institute is located in the heart of the city of Cambridge, and is part of the University's School of Biological Sciences. It is a world-renowned centre in developmental and cellular biology and cancer research. Supported by funding from the Wellcome Trust and Cancer Research UK, it benefits from state-of-the-art facilities including bioinformatics, media preparation and animal husbandry. It provides the best atmosphere for research and a vibrant environment that facilitates the interactions and collaborations between scientists within the Centre and within Cambridge. Its postdoc association encourages scientific and social interactions and provides career development and teaching opportunities.

For informal enquiries, contact Julie Ahringer (ja219@cam.ac.uk)

Limited funding: The funds for this post are available for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PR05744 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Research Associate/Senior Research Associate - Bioinformatics

From Jobs at the University of Cambridge. Published on Mar 25, 2015.

We are seeking a talented and motivated bioinformatics post-doctoral research associate to investigate genome organisation and gene expression in the group of Professor Julie Ahringer. Our research programme uses a variety of high throughput sequencing data (e.g, ChIP-seq, Hi-C, RNA-seq, ATAC-seq) and other genome-wide data types to study local and large-scale chromatin regulation. The successful applicant will work collaboratively within our lively research laboratory to analyse new and existing data, which would include the development of new methods.

The successful applicant should have a PhD in a relevant subject, a sound understanding of molecular biology, and a desire to work on cutting edge aspects of gene regulation. Experience in scientific programming and the analysis of Illumina sequencing data, a working knowledge of statistics, and a publication track record in bioinformatics are essential.

The Gurdon Institute is located in the heart of the city of Cambridge, and is part of the University's School of Biological Sciences. It is a world-renowned centre in developmental and cellular biology and cancer research. Supported by funding from the Wellcome Trust and Cancer Research UK, it benefits from state-of-the-art facilities including bioinformatics, media preparation and animal husbandry. It provides the best atmosphere for research and a vibrant environment that facilitates the interactions and collaborations between scientists within the Centre and within Cambridge. Its postdoc association encourages scientific and social interactions and provides career development and teaching opportunities.

For informal enquiries, contact Julie Ahringer (ja219@cam.ac.uk)

Limited funding: The funds for this post are available for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PR05743 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Research Associate - Molecular Mechanisms of Lysosomal Fusion

From Jobs at the University of Cambridge. Published on Mar 24, 2015.

Applications are invited for a Research Associate (fixed term) to investigate the molecular basis of lysosomal membrane fusion. The successful applicant will join a multidisciplinary team that aims to define how cells regulate the docking and fusion of lysosomes with organelles such as late endosomes or autophagosomes. Understanding this process will help us understand a range of processes important for health, from processing of peptides implicated in neurodegeneration to infection of cells by Ebola virus.

The post will be held at the Department of Pathology in the laboratory of Dr Stephen Graham, located on the Cambridge Biomedical Campus. Candidates should have a PhD, or expect to obtain one shortly, and have a strong background in cell biology, molecular biology or biochemistry. Experience in one or more of the following is essential: (i) use of unbiased screening approaches to identify novel protein:protein interactions; (ii) investigation of protein:protein interactions using cell-based or biochemical assays; (iii) characterisation of protein:protein interactions using biochemical, biophysical and/or structural approaches. Prior experience using proximity-based biotinylation (BioID) or investigating eukaryotic membrane trafficking would be advantageous. The laboratory employs a wide range of techniques and support will be available for the successful candidate to expand their skills.

The ability to work both independently and as part of a team, coupled with excellent communication, organizational and problem solving skills are required. The duties/responsibilities of this post include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures as outlined on the Further Information Document.

Fixed-term: The funds for this post are available for 18 months or until 31 December 2016 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05435 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

University Senior Lecturer

From Jobs at the University of Cambridge. Published on Mar 20, 2015.

Applications are invited for a University Senior Lectureship in Histopathology (non-clinical) in the Department of Pathology at the University of Cambridge to take up the appointment as soon as possible.

Applicants must be educated to degree level, normally with a PhD in relevant specialist subject area. Applicants for appointment are expected to demonstrate excellence in research, and a commitment to teaching at both undergraduate and postgraduate levels. The successful candidate will have a strong publication record in research into the pathology of human disease.

The potential to attract independent research funding is essential.

The purpose of the role is to strengthen the Department's basic and applied research and its teaching and training of undergraduate and graduate students, and to support and maintain the University's national and international reputation for excellence in teaching and research.

The successful candidate will be expected to pursue academic research at an international level of sufficient quality to be returnable in the Research Excellence Framework, including developing a research group and attaining research funding.

As a University Teaching Officer, the appointee will be expected to conduct small group teaching of undergraduates and to contribute to directing studies for programmes within their subject area. The successful candidate will be expected to participate in Department of Pathology teaching of general pathology to second and third year undergraduates leading to the Medical and Veterinary Sciences Tripos or the Natural Sciences Tripos.

For informal discussions please contact the Head of Division, Professor Nicholas Coleman by email at nc109@cam.ac.uk.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The deadline for applications is 5pm on Monday 22 April 2015. Short-listed candidates will be invited to visit the Department, to give a seminar on their work and meet prospective colleagues, prior to a meeting of the Appointments Committee. It is intended to arrange these visits in the weeks commencing 11th and 18th May 2015.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05639 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Junior Clinical Training Scholarship in Equine Studies

From Jobs at the University of Cambridge. Published on Mar 20, 2015.

UNIVERSITY OF CAMBRIDGE DEPARTMENT OF VETERINARY MEDICINE

One-year Junior Clinical Training Scholarship £14,700.00 per annum

Start date 1 August 2015

Fixed-term: 1 years.

Applications are invited from recently qualified veterinarians for this 12 month post-graduate training programme offering high-quality, post-graduate training in equine studies. The emphasis will be on gaining practical clinical experience in equine medicine and surgery under the supervision of board-certified specialists, and will allow the Scholar to identify specific fields in which to specialise, either in preparation for Senior Clinical Scholarship training programmes, or specialist private practice.

An applicant must be a Member of the Royal College of Veterinary Surgeons, or hold a veterinary degree qualifying him or her for membership.

For informal enquiries about the scholarship programme, please contact Kate Smith, University Equine Surgeon, ks629@cam.ac.uk or 01223 746571.

Closing date: 4th May 2015

Interview date: 19th May 2015

Application form (JCTS1) and information pack: contact Melissa Large on 01223 337055, quoting title of Scholarship, or download from the link below:

Completed application form, curriculum vitae and covering letter: send to Melissa Large, Department of Veterinary Medicine, Madingley Road, Cambridge, CB3 OES, or submit via email vetmed@hermes.cam.ac.uk

Please quote reference PP05716 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 20, 2015.

University of Cambridge Department of Veterinary Medicine West Cambridge Site Research Associate

Limit of Tenure: 18 months

Applications are invited for this postdoctoral position in computational statistics, funded by BBSRC, with the task of developing software for Bayesian optimal experimental design and inference.

The position is part of a new project led by Drs Restif and Dybowski which aims to produce a functional computational package to facilitate the complete integration of dynamic models and laboratory experiments in microbiology and infectious disease research. The successful applicant will be responsible for the development of an open-source software with two related and essential functions: statistical inference and optimal experimental design (OED). This 18-month project will enable us to test the functionality of the package on different experimental systems using existing and new data, before releasing it for free and public use in inter-disciplinary biological research. This package will provide life scientists with a "one-stop shop" that facilitates the full integration of experiments and dynamic models.

This project capitalises on the unique multi-disciplinary expertise within the Disease Dynamics Unit (Department of Veterinary Medicine), which is the largest research team in Cambridge working at the interface of models and experiments on infectious diseases.

Applicants should have a PhD, or significant experience in applied mathematics or a related discipline, must be familiar with state-of-the-art Bayesian methods, and must have solid scientific programming skills in R and other languages. Experience of package development for R, and of collaboration with experimental scientists are an advantage. The candidate must value teamwork and collaboration, and must be able to work to deadlines.

Informal enquiries should be directed to Dr Olivier Restif (or226@cam.ac.uk)

Close Date: 29th April 2015

Interview Date: 12th May 2015

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should submit a CHRIS/6, CV, covering letter outlining suitability for the role and contact details for two references. Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application. Further particulars for the role and information about the Department www.vet.cam.ac.uk

Please quote reference PP05718 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Senior Horticultural Technician - Alpine and Woodland

From Jobs at the University of Cambridge. Published on Mar 20, 2015.

Salary: £24,775 - £28,695 pa Monday to Friday inclusive (36.5 hours per week average) Hours of work vary depending on the season of the year.

Alpine and Woodland Section is one of seven sections that comprise the Garden's horticultural department, each responsible for caring for a specific area of the Garden and its plant collections. Reporting directly to the Head of Horticulture, the role-holder leads the team responsible for the maintenance, cultivation and curation of the Alpine and Woodland collections. This role is supported by one full-time horticultural technician and one full-time trainee horticultural technician assigned to the Section on rotation. Work experience placements and volunteers, under the supervision of the Alpine and Woodland supervisor, will occasionally be assigned to the Section.

The Section comprises the Alpine House, Alpine Yard, Limestone and Sandstone Rock Gardens, Woodland Garden, Stream and Bog Garden, Lake and associated areas. The role-holder will deliver excellent horticultural knowledge and standards within the Section, and is responsible for the maintenance, cultivation and curation of all areas and collections within the Section, in support of the Garden's core activities e.g. University teaching and research, education and amenity. The successful candidate will lead and organise the team responsible for the maintenance, cultivation and curation of specialised Alpine and Woodland collections comprising alpine, bulbous, herbaceous and shrubby species from a range of habitats and environments. They will supervise one horticultural technician and one trainee horticultural technician working on the Section.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Interviews: week commencing 27 April 2015

For any questions regarding this post, please e-mail admin@botanic.cam.ac.uk

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Postdoctoral position in G-protein-coupled receptors (GPCRs) (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 19, 2015.

A postdoctoral position is available immediately to work in the laboratory of Dr Daniel Nietlispach, University of Cambridge, Department of Biochemistry, UK.

The research involves the study of G-protein-coupled-receptors (GPCR) and the role that dynamics play in the functional activation of such receptors. A multi-disciplinary approach is followed including NMR spectroscopy and other biophysical methods. The Departmental research facilities include extensive state-of-the-art high field NMR instrumentation (500-800 MHz) and a comprehensive range of biophysics equipment.

Applicants should have a PhD in Biochemistry or the equivalent in a relevant subject. We are seeking a highly motivated individual with a strong background in protein biochemistry, including protein expression and structural biology of membrane proteins. Expertise in biomolecular NMR spectroscopy is of benefit but not a necessity. A suitable candidate will be able to plan and organise his research in an independent and efficient manner.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Fixed-term: The funds for this post are available for up to 17 months.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made to Dr Daniel Nietlispach - dn206@cam.ac.uk

Please quote reference PH05695 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Senior Research Laboratory Technician - Drosophila Neurobiology (Part Time, Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 19, 2015.

We are looking to appoint a technician to work 18.25 hours (0.5 FTE) per week in support of a BBSRC funded project on Drosophila (fruitfly) neurobiology.

The main duties include dissections of Drosophila larval axon and synapse preparations, antibody staining, confocal microscopy, Drosophila crosses, and collation and analysis of computerised image and spreadsheet data.

You should have an HND or equivalent in a biological or related science although a degree level education is desirable. At least 3 years laboratory experience in immunohistology, microscopic dissections, and mounting or imaging of dissected preparations, preferably Drosophila, is essential.

Fixed-term: The funds for this post are available until 31 December 2017 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries may be made to Dr. Cahir O'Kane (c.okane@gen.cam.ac.uk).

Please quote reference PC05697 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

University Lecturer (Honorary Consultant) x 2

From Jobs at the University of Cambridge. Published on Mar 18, 2015.

Applications are invited for two University Lectureships in Histopathology in the Department of Pathology at the University of Cambridge to take up the appointment as soon as possible. The primary focus of one position will be research and clinical duties, while the primary focus of the other will be teaching and clinical duties.

Applicants must be educated to degree level, normally with a PhD or MD in a relevant specialist subject area, licensed by the General Medical Council and be Fellows of the Royal College of Pathologists (or hold an equivalent postgraduate qualification), be on the Specialist Register in Histopathology and have a number of years' experience in clinical histopathology.

The successful applicants will be expected to develop and contribute to the teaching activities of the Department and participate in the Diagnostic Histopathology Service at Addenbrooke's Hospital. The themes of the applicant's diagnostic interests are not prescribed but should complement existing interests in the Department as described on its website (http://www.path.cam.ac.uk/)

The posts are available immediately and remunerated on the Clinical Academic Scale at Consultant level.

For informal discussions please contact the Head of Division, Professor Nicholas Coleman, by email at nc109@cam.ac.uk.

Once an offer of employment has been accepted, the successful candidates will be required to undergo a health assessment and a security check. These appointments also require an Honorary Clinical Contract.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The deadline for applications is 5pm on Monday 22 April 2015. Short-listed candidates will be invited to visit the Department, to give a seminar on their work and meet prospective colleagues, prior to a meeting of the Appointments Committee. It is intended to arrange these visits in the weeks commencing 11th and 18th May 2015.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05637 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Head Receptionist (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 17, 2015.

UNIVERSITY OF CAMBRIDGE DEPARTMENT OF VETERINARY MEDICINE WEST CAMBRIDGE SITE

Fixed-term: The funds for this post are available for 3 years in the first instance.

Applicants are invited for Head Receptionist at the Queen's Veterinary School Hospital. This is an exciting opportunity to join a team of receptionists in a leading role. The Head receptionist will be responsible for the supervision and deployment of the reception staff, over the Small and Large Animal Reception areas within the Hospital and the RSPCA clinic. The role holder will also be responsible for the upkeep and maintenance of a number of internal computer systems and will be the first point of contact for the phone system which has five incoming lines and fifty pager units.

It is essential that applicants should be educated to A level standard or equivalent with GCSE level in Maths and English or a number of years working in a clinical environment, veterinary referral hospital or first opinion practice. You should have excellent IT skills and have demonstrable experience of supervising staff.

Applicants must have a flexible approach to working in a team, be self motivated, organised with a methodical approach. Excellent interpersonal skills, communication skills and the ability to interact with members of the public in challenging circumstances are also a requirement. An understanding of medical terminology is desirable.

Informal enquiries please contact Pam Missenden Clinical Services Manager: Tel: 01223 337627 or email pam65@cam.ac.uk

Closing Date: 8 April 2015

Interviews will be held: 21 April 2015

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

To submit an application for this vacancy, please click on the link 'Apply online' This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) before completing the online application form.

Further particulars for the role and information about the Department www.vet.cam.ac.uk

Please quote reference PP05676 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

PhD Studentship (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 16, 2015.

A vacancy for a PhD student to be fully funded by the NC3Rs for 3 years is available in the Department of Biochemistry, Sanger Building, central Cambridge under the supervision of Dr Frank McCaughan and Professor Gerard Evan.

We have developed a novel organotypic (OTC) model of bronchial dysplasia/early lung cancer. In this system, immortalised normal human bronchial epithelial cells are grown at the air-liquid interface on a collagen matrix with embedded fibroblasts. In OTC there is a clear phenotype in cells in which the activation of putative oncogenes at the air-liquid interface recapitulates a histological phenotype consistent with human bronchial dysplasia/early lung cancer.

In vivo, multiple genetic lesions will co-operate to drive carcinogenesis. We have introduced complexity into our model by combining genetic lesions, which leads to a more marked phenotype.

There are two main objectives: 1) To perform a functional/phenotypic screen with an extended library of small molecule inhibitors in the OTC model of bronchial dysplasia 2) To use genome manipulation tools - CRISPR and lentiviral transduction and alteration of the microenvironment to recapitulate some of the complexity observed in vivo. These refined models will be used for mechanistic studies into lung cancer pathogenesis and to assess the impact of genotype on therapeutic response.

Candidates should have or expect to get a 2i or above in an appropriate discipline.

NC3Rs studentship conditions apply. Please see http://www.findaphd.com/search/PhDDetails.aspx?CAID=1091&LID=1263.

Fixed-term: The funds for this post are available for 36 months in the first instance.

To apply please send your CV and the names and contact details of two or more academic referees to Dr Frank McCaughan - fm319@cam.ac.uk.

Please quote reference PH05655 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Pluripotent Stem Cell Platform Executive Manager

From Jobs at the University of Cambridge. Published on Mar 16, 2015.

Limited funding: The funds for this post are available until 31 January 2018 in the first instance.

Three UK Research Councils; Biotechnology and Biological Sciences Research Council, Engineering and Physical Sciences Research Council and the Medical Research Council have invested £25m in research and equipment to support development of the UK Regenerative Medicine Platform (UKRMP www.ukrmp.org.uk). The Pluripotent Stem Cell Platform (PSCP) is one of five Hubs funded by the UKRMP to tackle critical challenges in developing new regenerative treatments from discoveries made in the laboratory. PSCP brings together researchers from several institutions to develop the processes needed to take pluripotent stem cells from laboratory-based research to the commercial manufacture of safe, effective and reproducible products for use in regenerative medicine.

PSCP now has an exciting opportunity for a Project Manager who has held a management role in a complex environment and has a proven track record in business/ bioindustry whilst empathising with academic ethos.

We are looking for a highly motivated individual to manage projects effectively according to industry best practice, determining and delivering to agreed scope, quality, budget and deadlines. The Project Manager will manage a number of projects concurrently and will maintain accurate project plans, work schedules, issue and risk logs to enable projects to be delivered successfully and will coordinate regular meetings at the different partner sites. The successful applicant will be commercially astute, intellectually agile with excellent communication skills. You will be educated to at least degree level and have a further qualification (MSc, PhD or MBA). You will be able to demonstrate your ability to build effective relationships with funders, engage with experts worldwide, develop summary documents and reports, organise meetings and associated administration, and deliver effective work related communication.

Hands on experience of budgeting, funding applications and administration in a research- led environment would be highly advantageous as would experience of working as part of a senior management team with budgetary responsibility and accountability for group and individual performance.

The role-holder will be a confident and articulate communicator and will possess a highly collaborative and inspirational leadership style with a track record of managing and developing multi-disciplinary teams as well as building relationships with external partners.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Sunday 26th April 2015.

Informal enquiries about the post are also welcome via email on cscrjobs@cscr.cam.ac.uk.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Interviews will be held on Monday 11th May 2015. If you have not been invited for interview by 7th May 2015, you have not been successful on this occasion.

Please quote reference PS05620 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Senior Chief Building Services Technician

From Jobs at the University of Cambridge. Published on Mar 16, 2015.

Limited funding: The funds for this post are available until 30 June 2017 in the first instance.

The Cambridge Stem Cell Institute is a world-leading centre of excellence in stem cell biology and regenerative medicine, supported by the Wellcome Trust and the Medical Research Council (www.stemcells.cam.ac.uk). The Institute comprises over 300 researchers spanning fundamental science through to clinical applications. Our vision is of a deep understanding of stem cell biology for the prevention and treatment of human disease.

We are seeking a dynamic and self-motivated individual with the skills and experience to lead the building services and maintenance team at our main building located in the Centre of Cambridge.

The building hosts approximately 200 researchers from a variety of Institutes/departments and the role holder will assist the Principal Technician with providing front of line building services and maintenance for everyone based in the building. You will be responsible for the complex plant and services on all five floors as well as the associated building services equipment and the coordination of contractors.

The role holder will manage the day to day operation of the mechanical equipment and the steam plant and will organise and control a reactive (24hr) maintenance service for all mechanical and electrical services. The role holder is the first point of contact with the University's Maintenance Unit (MU) as well as other directly employed specialist contractors and will assist in the preventative maintenance and/or repair of our laboratory equipment including electrical testing and fault-finding.

Your expertise in managing a steam plant will be matched with your understanding of a laboratory environment and associated regulations to comply with relevant Health & Safety legislation. You will have a flexible approach to your workload and be able to balance the needs of the research environment as well as work efficiently within a team. You will have excellent communication skills, both verbal and written. You will have good people management skills and the ability to use standard Microsoft software including Word and Outlook. Experience with laboratory equipment is desirable.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a security check.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Wednesday 15th April 2015.

Informal enquiries about the post are also welcome via email on cscrjobs@cscr.cam.ac.uk.

Interviews will be held on Friday 24th April 2015. If you have not been invited for interview by 21st April 2015, you have not been successful on this occasion.

Please quote reference PS05656 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 13, 2015.

Applications are invited for a postdoctoral position in the Department of Pathology, University of Cambridge, based in central Cambridge to investigate necroptosis and alternative cell death mechanisms. The project will investigate various signalling pathways and their role in the induction of cell death in mammary gland in vivo and in normal and tumourigenic breast cells. Experienced postdoctoral scientists who have the expertise to drive this project forward in collaboration with others in the laboratory of Professor Christine Watson are invited to apply for this position.

This project is funded by a Medical Research Council programme grant. Candidates will be expected to have a PhD in molecular or cell biology with a track record of publishing in high quality journals, expertise in genome editing technologies and high resolution imaging and an interest in mechanisms of cell death in normal and cancer cells. Ability to work both as part of a team, and independently, coupled with excellent communication, organizational and problem solving skills are required. The duties/responsibilities of this post include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures as outlined in the further information document.

Specific enquiries, and requests for more details of the project, can be made to Christine Watson at cjw53@cam.ac.uk.

Fixed-term: The funds for this post are available until 13 May 2017 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK04787 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate in Cognitive Neuroscience (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 13, 2015.

One full-time postdoctoral research position is available immediately to work with Professor Trevor W. Robbins and Professor Barbara J. Sahakian to investigate fronto-striatal systems in impulsive-compulsive disorders, as part of a programme funded via a Wellcome Trust Senior Investigator Award to Prof TW Robbins. The post holder will work under the umbrella of the University of Cambridge Behavioural and Clinical Neuroscience Institute (BCNI, Director: Prof Robbins).

The role holder will be part of a multi-disciplinary research group working towards elucidating the overarching question of how impulsive-compulsive symptoms of psychiatric disorders can be understood in terms of common aberrations of psychological processes arising from dysfunction of discrete neural systems. Within this programme the role holder will work predominantly on neuroimaging, neuropsychological and psychopharmacological aspects.

Applicants should have a Ph.D. in cognitive neuroscience, psychology, or related disciplines. Previous experience in learning theory, cognitive or clinical neuropsychology and/or neuroimaging, as well as neurocomputational methods, would be an advantage as would be experience in interacting with patients with OCD. Specific skills in functional connectivity and other neuroimaging methodologies are desirable, but not essential, as training will be provided.

Informal enquires should be directed to Prof TW Robbins, email:twr2@cam.ac.uk

Further information may be downloaded below.

Fixed-term: The funds for this post are available for 24 months in the first instance.

Interviews expected to take place in the week beginning 20 April 2015

This appointment requires a Research Passport application.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

If you do not hear from us within 4 weeks of the closing date please assume your application has been unsuccessful.

Please quote reference PJ05624 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term) - Medicago symbiosis

From Jobs at the University of Cambridge. Published on Mar 12, 2015.

Applications are invited for a Post-doctoral Research Associate position in the group of Dr Sebastian Schornack (http://www.schornacklab.net) at the Sainsbury Laboratory (SLCU), Cambridge University, to study colonisation processes of filamentous microbes in plants.

The overall aim of this position is to study the interaction of Medicago truncatula with beneficial symbionts and detrimental pathogens. We have recently identified a significant overlap between symbiotic and pathogenic interactions (see Rey et al, 2014, New Phytol. DOI: 10.1111/nph.13233). The successful candidate will take advantage of our established experimental systems to study the interaction of Phytophthora palmivora and mycorrhiza fungi with Medicago truncatula using genetics, transcriptomics, microscopy and biochemical approaches. Candidates will also be able to develop their own research objectives and proposals such as evolutionary aspects of colonisation processes within the frame of our general research. The candidate will be provided with horticultural/technician support and will be able to team up with post docs studying microbial effector biology and monocot resistance breeding.

Candidates must have or be close to finishing a PhD in a relevant discipline (e.g. plant biology, plant biochemistry). Previous experience with Medicago truncatula, Lotus japonicus or similar legumes is desirable. Proficiency in qPCR analysis, cloning and fluorescence microscopy is also required.

The successful candidate will be fully involved in the basic research in these areas whilst also writing up their research work for presentation and publication. The post holder may be required to assist in the supervision of student projects, provide instructions to students and deliver seminars relating to their research area.

Good communication skills are essential as the post holder will need to work well in a team and collaborate with other researchers in the Institute. Candidates would ideally have published or submitted papers in this area. Candidates should demonstrate a history of science communication (e.g. presentations, outreach activities, teaching).

Information about the Sainsbury Laboratory and the generic further particulars for the role can be found at: http://www.slcu.cam.ac.uk/

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload a copy of your full CV, a supporting statement and contact information of three referees.

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within three weeks of the closing date, please consider your application as unsuccessful on this occasion.

Please quote reference PT05617 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate - Bioinformatician (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 12, 2015.

Fixed-term: The funds for this post are available until 30 September 2017 in the first instance.

Applications are invited for a computational biologist to join the research group of Dr Paul Bertone at the Wellcome Trust - Medical Research Council Stem Cell Institute at the University of Cambridge. We are applying state-of-the-art experimental and computational methods toward the understanding of transcriptional regulation in pluripotent stem cells from rodents and primates.

We work closely with the groups of Dr Jennifer Nichols and Professor Austin Smith at the SCI, and seek to fill this position with a postdoctoral scientist who will join a new collaborative project funded by the BBSRC. This arrangement provides an excellent environment for research and career development, as the post holder will benefit from the resources and expertise of both experimental and computational environments to lead this multidisciplinary initiative.

The group applies large-scale gene expression profiling, comparative genomics and regulatory systems modelling to mammalian embryogenesis and stem cell biology. The post holder will have the opportunity to lead related computational projects, but will also work in partnership with experimentalists and contribute to the design and execution of collaborative studies. He or she will have a strong publication record, excellent communication skills, and enjoy working on ambitious projects at the frontiers of genomics and biotechnology.

Candidates will have a solid background in computation and current knowledge of eukaryotic genomics. Expertise in statistical methods and Unix scripting are essential. Additional experience with high-throughput sequencing data, numerical computing or regulatory systems modelling is desirable but not required. Applicants should hold a PhD in a relevant field (e.g. Bioinformatics, Applied Mathematics, Computer Science, Biomedical Engineering, or Biochemistry/Molecular Biology with a computational component). Previous experience in stem cell biology is not necessary.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Monday 20th April 2015.

Informal enquiries about the post are also welcome via email: cscrjobs@cscr.cam.ac.uk.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Interviews will be held towards the beginning of May 2015.

Please quote reference PS04734 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Glasswashing and Media Technician (Part Time, Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 11, 2015.

The Sainsbury Laboratory is a research Institute sited within the University Botanic Gardens which focuses on plant developmental biology and computational modelling of plant development. When full, the Institute will have some 120 researchers and around 30 support staff.

Applications are invited for the part-time position of Glasswashing and Media Technician to be part of a small team, working closely with another Technician in the Institute glass washing, autoclaving and media prep facility. The post holder will be an essential part of the research support team which ensures the smooth running of the research operations.

Candidates will ideally have a BTEC in biological sciences; experience in laboratory work, including preparation of sterile solutions and quality control is essential. The post demands good judgement, an ability to work independently and prioritise, alongside good attention to detail in order to produce consistent top quality output. Good communication skills are also essential, as well as the ability to work as part of a team.

The glass washing and media facility is a vital component of the Institute's core services. It provides and maintains clean glassware suitable for research activities, sterilisation services, and a range of standard solutions for the research groups, including general media, tissue culture media, culture plates, and other products as needed.

Information about the Sainsbury Laboratory and further information for the role can be found at: http://www.slcu.cam.ac.uk/

The post is part time at 0.5FTE and available immediately.

Fixed-term: The funds for this post are available until 31 December 2016 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within three weeks of the closing date, please consider your application as unsuccessful on this occasion.

Please quote reference PT05604 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Stores Technician (Part Time, Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 11, 2015.

The Sainsbury Laboratory is a research Institute sited within the University Botanic Gardens which focuses on plant developmental biology and computational modelling of plant development. When full the Institute will have some 120 researchers and around 30 support staff.

Applications are invited for the position of a part-time Stores Technician to be responsible for supporting the existing Stores facility, in order to accommodate an expanding requirement as the Institute grows. The role holder will be part of a two person Stores team providing an efficient service to the employees and performing some ad-hoc purchasing duties as required. The role holder will also work closely with the Purchasing Supervisor to assist with supporting existing procurement Stores policies. A proactive, service-orientated approach is essential.

Candidates must have a good level of education and ideally have CIPS Level 2 and CUFS/Oracle experience. They must also have experience of working within a stores environment and be proficient in relevant stores processes.

The successful candidate will be competent in standard software packages, e.g. Word, Excel, Access, Outlook and have an awareness of current Health and Safety legislation. Ownership of a forklift licence and manual handling certificate would be an advantage.

The ability to prioritise own workload and communicate with people at all levels will be paramount.

Information about the Sainsbury Laboratory and further information for the role can be found at: http://www.slcu.cam.ac.uk/

The post is part-time at 0.5FTE and available immediately.

Fixed-term: The funds for this post are available until 31 December 2016 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within three weeks of the closing date, please consider your application as unsuccessful on this occasion.

Please quote reference PT05607 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Administrative Assistant - Data (Part Time Maternity Cover)

From Jobs at the University of Cambridge. Published on Mar 11, 2015.

Maternity cover: This post is fixed-term until 24 December 2015 or the return of the post holder, whichever is the earlier.

The Stem Cell Institute has an exciting opportunity for an outstanding administrator to join our friendly and dynamic administrative team in the centre of Cambridge.

We are a world-leading centre of excellence in stem cell biology and regenerative medicine supported by the Wellcome Trust and the Medical Research Council (www.stemcells.cam.ac.uk). The Institute comprises over 300 researchers spanning fundamental science through to clinical applications. Our vision is a deep understanding of stem cell biology for the prevention and treatment of human disease.

The role is primarily responsible for maintaining accurate data on the activities of our 300+ researchers. This data is used to create reports for our funders, support grant applications and provide content for our annual brochure, so accuracy and attention to detail are vital. You will need to keep track of our researchers' journal publications, outreach events and conferences attended, as well as prizes, honours and awards received. The role holder is also responsible for updating elements of our websites, including posting news articles about significant publications, and will maintain a database of images for use in our brochures, websites, posters and other Institute materials. You will be the link between the Institute and a number of University central services and will advise and assist Institute members on payment of open-access fees for journal publications.

You will be able to demonstrate excellent interpersonal / communication skills and a good telephone manner with a positive, service-oriented, "can do" attitude. It is essential that the role holder be tactful, diplomatic and patient. You will be confident in using the internet and competent in standard IT software packages including Microsoft Word, Excel and Outlook. Database experience (inputting data), good organisation skills and the ability to multi-task are essential for this role. Experience of website content management systems as well as Microsoft Publisher and Access would be useful although not essential (as this can be taught). The Institute is a supportive but busy environment, so you must be able to prioritise and work to tight deadlines with minimal supervision.

It is important that you can demonstrate a close attention to detail / high level of accuracy and you must be an excellent team player. The role holder will be responsible for creating and maintaining excellent relationships with staff throughout the Institute so you must find it easy to build rapport with individuals of every level.

The role holder does not require any specific qualifications but a good general knowledge to GCSE standard, including English and Mathematics, is essential.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Tuesday 7th April 2015.

Informal enquiries are also welcome via email: jrw46@cam.ac.uk.

Interviews will be held Thursday 16th April 2015. If you have not been invited for interview by 13th April 2015, you have not been successful on this occasion.

Please quote reference PS05613 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

EEG/MEG Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 11, 2015.

Applications are invited for a full-time Research Associate to work on the final year of a five-year longitudinal project investigating auditory processing abilities and neural phase locking in dyslexic and control children. The position is available from 1 June 2015 or as soon as possible thereafter.

Applicants should ideally have a PhD in neuroscience or psychology, and experience of designing, administering and analysing MEG and EEG experiments, ideally involving oscillatory paradigms and time-frequency analyses. Experience with fNIRS would be an advantage. They require excellent mathematical and technical skills (e.g. Matlab, wavelet analysis). Applicants will require the capacity to work independently running MEG or EEG studies and analysing data.

Further information may be downloaded below.

Fixed-term: The funds for this post are available for 12 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo an enhanced Disclosure and Barring Service check.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

If you do not hear from us within 4 weeks of the closing date please assume your application has been unsuccessful.

Please quote reference PJ05596 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 10, 2015.

Applications are invited for a Post-doctoral Research Associate position in the group of Dr Philip Wigge at The Sainsbury Laboratory, Cambridge University, to work on a project focussing on the mechanisms by which chromatin status impacts transcriptional programs in response to temperature. The role holder will concentrate on the characterisation of a family of chromatin binding proteins in Arabidopsis thaliana that have recently been discovered in the Wigge laboratory and will generate experimental data for a grant application on the topic. The ultimate goal of the research is to make crop plants resilient to field stress conditions and thus contribute to the economic competitiveness of the UK.

Applicants must have a PhD in Cell Biology, Molecular Biology, Genetics or related field. Prior experience, preferably supported by a strong publication record, in biochemistry of chromatin binding proteins is essential, as well as a thorough experimental grounding in molecular cell biology. Special skills and knowledge include 1/ a deep understanding of chromatin biology 2/ an advanced knowledge of, and experience in, protein-protein interaction assays and 3/ extensive experience of assaying temperature responses in Arabidopsis thaliana seedlings. Experience in proteomics, mass spec identification of proteins, and chromatin immunopurification would be an advantage.

The role holder must be able to communicate clearly and present data to other members of the group, external collaborators and sponsor agencies (grant application). Candidates will also need to work well in a team.

Information about the Sainsbury Laboratory and the generic further particulars for the role can be found at: http://www.slcu.cam.ac.uk/

Fixed-term: The funds for this post are available until 29 February 2016 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload a copy of your full CV, a supporting statement and contact information of three referees.

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within two weeks of the closing date, please consider your application as unsuccessful on this occasion.

Please quote reference PT05595 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Blanpain & Simons Lab) (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 10, 2015.

Fixed-term: The funds for this post are available for 12 months in the first instance.

Laboratory of Professors Cédric Blanpain and Benjamin Simons:

Applications are invited for a post-doctoral position to study stem cell dynamics in epidermis using culture systems and mouse models. The project aims at understanding the molecular mechanisms regulating asymmetrical versus symmetrical stem cell division during tissue homeostasis and repair. In a multidisciplinary and correlative project at the frontier between biology and physics, clonal analysis and single cell molecular profiling combined with bio-statistical approaches will be used to unravel the rules and molecular determinants regulating these fundamental processes.

Candidates will be motivated and equipped to pursue challenging research questions in the field of stem cell and developmental biology. You will have a PhD with specific research experience in cell and/or developmental biology. Prior work with epidermal stem cells is not required, as training will be provided. You will enjoy working as part of a multidisciplinary team while taking responsibility for your own research project. You will have first author publications and a proven capacity to design and interpret incisive experiments.

The Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute draws together outstanding researchers from 25 stem cell laboratories in Cambridge to form a world-leading centre for stem cell biology and medicine (http://www.stemcells.cam.ac.uk/).

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Sunday 12th April 2015.

Informal enquiries about the post are also welcome via email to Professor Benjamin Simons : bds10@cam.ac.uk, or Professor Cedric Blanpain : Cedric.blanpain@ulb.ac.be.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Interviews will be held week commencing 20th April 2015. If you have not been invited for interview by 20th April 2015, you have not been successful on this occasion.

Please quote reference PS05531 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Bioinformatician/Computational Biologist)

From Jobs at the University of Cambridge. Published on Mar 09, 2015.

Applications are invited for a Postdoctoral Research Associate in the laboratory of Professor Azim Surani. We are investigating the mechanism of mammalian germline, early development and stem cell biology. The work includes genome-wide analysis of high throughput sequencing data of transcriptional networks regulating cell fate decisions, regulatory elements and epigenetic programming (chromatin modifications, DNA methylation) in response to environmental and signalling cues. We are working on mouse and human, amongst other organisms, to gain comprehensive insights on underlying mechanisms. We also use single cell analysis. Expertise in the analysis of next-generation sequencing data and related statistical methods is essential. Previous experience in modeling regulatory networks and epigenetic states and willingness to become familiar with the biological systems under investigation is an advantage. Applicants should have a PhD in a relevant subject. The group is based at the renowned Gurdon Institute at the University in the centre of Cambridge. Please contact Azim Surani for informal enquires (a.surani@gurdon.cam.ac.uk)

Limited funding: The funds for this post are available for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PR05581 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Postdoctoral Research Associate in Neurobiology/Biophysics (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 09, 2015.

This postdoctoral position at the interface between neurobiology and biophysics is available immediately in the group of Kristian Franze. The lab combines biophysical and cell and molecular biological approaches to understand the influence of physical cues on the functioning and malfunctioning of the nervous system.

You will be working on a project aimed at investigating the role of mechanical signals in neuronal regeneration. Changes in the mechanical environment of neurons after injury will be studied using a variety of techniques including atomic force microscopy and confocal laser scanning microscopy.

The successful candidate should hold a PhD in cell or neurobiology, biophysics, bioengineering, or a related subject. Strong expertise in either small animal (e.g., mouse or lower vertebrates) surgery or atomic force microscopy is required. Experience with Matlab would be an advantage. Motivation to work in a multidisciplinary environment is fundamental to this position. An ability to work independently and take responsibility for his/her own project as well as good teamwork and communication skills are expected.

Informal enquires regarding the position should be made to Dr Kristian Franze:

Email: kf284@cam.ac.uk Tel: +44 (0)1223 333761 http://www.pdn.cam.ac.uk/staff/franze

*Fixed-term: The funds for this post are available for 1 year in the first instance with a possible extension for a further 12 months depending on funding.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Closing Date: 9 April 2015

Please quote reference PM05577 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 06, 2015.

A position is open for a postdoctoral research associate as part of the OpenPlant Synthetic Biology Research Centre at the University of Cambridge, under the direction of Dr. Jim Ajioka based in central Cambridge.

The appointee will develop a research project based on the development of new synthetic biology tools for engineering the plastid genome in the model plant Marchantia polymorpha. Work with Marchantia allows streamlined approaches to genome modification, secondary metabolism and morphogenetic engineering. We are looking for a highly motivated post-doctoral scientist to work in this area. The position is available as a full-time position for 30 months.

The successful candidate will have a strong background in plant molecular biology, yeast genome engineering or synthetic biology, including a PhD in a relevant area. Experience with synthetic biology approaches, handling large DNAs, plant or yeast molecular biology will be advantageous.

OpenPlant is a BBSRC-EPSRC funded Synthetic Biology Research Centre. It is based in the United Kingdom and is a collaboration between the University of Cambridge and the John Innes Centre and The Sainsbury Laboratory, Norwich. The OpenPlant SBRC is focused on the development of open foundational technologies for plant synthetic biology and their application for engineering new traits in crop systems. OpenPlant will (i) fund interdisciplinary efforts in plant Synthetic Biology, to explore novel foundational technologies and applications, build shared resources and provide a point of exchange for young scientists and entrepreneurs; (ii) promote two-tier intellectual property models that will promote sharing of DNA components and freedom-to-operate for commercial applications of plant synthetic biology, and (iii) address responsible innovation, and explore the potential wider impacts of synthetic biology on sustainable practices in agriculture, bioproduction, land use and environmental conservation. (http://www.openplant.org)

The ability to work both as part of a team, and independently, coupled with excellent communication, organizational and problem solving skills are required. The duties/responsibilities of this post include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures as outlined on the Further Information Document.

Applicants should provide a CV, the filename of which should be "CV-followed by your name", including contact details of two or more referees, and a covering letter addressing the selection criteria.

For further information contact Dr Jim Ajioka (ja131@cam.ac.uk)

Fixed-term: The funds for this post are available for 30 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05505 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Chalut & Franklin Lab) (Fixed Term)

From Jobs at the University of Cambridge. Published on Mar 05, 2015.

Fixed-term: The funds for this post are available for 3 years in the first instance.

The Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute (SCI) comprises 200 researchers spanning fundamental science through to clinical applications (http://www.stemcells.cam.ac.uk/). Our goal is to advance disease modelling, drug discovery and regenerative medicine through understanding the mechanisms that control stem cell fate.

We are seeking an enthusiastic and highly motivated person to join the SCI to be co-supervised by Dr. Kevin Chalut and Prof. Robin Franklin. This project, which is also a collaboration with Dr. Ulrich Keyser in the Department of Physics, will investigate the role of the mechanical and material properties of the cell nucleus in regulating cell fate decisions. This BBSRC-funded project, continues our recently published work (Pagliara, et al., Nature Materials, 2014), which outlined the role of force-induced changes in nuclear shape and volume during stem cell differentiation.

We are seeking motivated researcher with a proven track record of successful research. The candidate must have a PhD in Physics or Biology or at the interface. It is essential that the candidate is driven to use principles of physics to better biological questions. The successful applicant should have experience in molecular biology techniques, cell culture and advanced microscopy. It would be beneficial for the candidate to have experience in biophysical techniques such as microfabrication and/or atomic force microscopy. In this collaborative project the candidate will need to show their ability to work within a highly interdisciplinary team.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Sunday 5th April 2015.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Informal enquiries are also welcome via email: cscrjobs@cscr.cam.ac.uk.

Interviews will be held on Thursday 16th April 2015. If you have not been invited for interview by 13th April 2015, you have not been successful on this occasion.

Please quote reference PS05553 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Marie-Sklodowska-Curie ITN PhD Studentship

From Jobs at the University of Cambridge. Published on Mar 03, 2015.

A 3-year EU-funded PhD studentship is available in the laboratory of Dr Martin Welch. Applications are invited for a PhD studentship position ("Early Stage Researcher" or ESR) to be funded by the Marie-Sklodowska-Curie Innovative Training Network "INTEGRATE ¿ Interdisciplinary Training Network for Validation of Gram-Negative Antibacterial Targets" within the Horizon 2020 Programme of the European Commission. Researchers are required to undertake trans-national mobility (i.e., move from one country to another) when taking up the appointment.

Project Title: The glyoxylate shunt as a target for antibacterial intervention in Gram-negative bacteria.

The junction between the TCA cycle and the glyoxylate shunt is widely regarded as one of the most important metabolic branchpoints in the whole of microbial metabolism, and is increasingly being recognized as a major new target for the development of antibacterial compounds (Munoz-Elias & MacKinney, Nature Medicine 11, 638 - 44 (2005) & Sharma et al. Nat Struct Biol. 7(8):663-8 (2000)). In addition, carbon flux through the glyoxylate shunt plays a central role in regulating virulence in the Gram-negative "superbug", Pseudomonas aeruginosa (Chung et al, Open Biology (2013)). Indeed, mutants defective in isocitrate lyase (ICL; the first enzyme of the glyoxylate shunt) display impaired fitness in vivo. Consequently, compounds that target the enzymes of the glyoxylate shunt, or which reduce the flux of carbon directed through this pathway, may have the dual effect of reducing tissue damage (by blocking virulence) and diminishing the metabolic fitness of the organism in the niche. However, the branchpoint between the TCA cycle and glyoxylate shunt in P. aeruginosa differs markedly from the canonical organisation in E. coli, and nothing is known about its enzymology. The aim of this PhD project is to purify the enzymes involved, and to characterize these in considerable detail as potential targets for antimicrobial intervention. The kinetic parameters of each P. aeruginosa branchpoint enzyme (which includes two isocitrate dehydrogenases (ICD and IDH), a kinase/phosphatase (AceK) and ICL) will be determined, as will the impact of putative allosteric regulators. HTP screening of compound libraries (including natural product and Diversity oriented synthesis (DoS) libraries, available in-house) will be carried out to identify inhibitors/activators of each enzyme. We will characterize the nature of the inhibition/activation mechanisms (competitive, non-competitive, etc.) and attempt to co-crystallize these compounds as complexes bound to their cognate target enzymes.

The appointed ESR will spend at three months seconded to Aptuit (Verona, Italy) and five months seconded with the University of Helsinki (Finland) to allow them to learn and apply new techniques.

Shortlisted candidates will be invited the INTEGRATE Recruitment Event in Verona (Italy) on 5-6 May 2015. The Recruitment Committee will subsequently interview each candidate. In order to cover (part of) your travel and lodging costs, shortlisted candidates will receive a lump sum of €250.

The project will start during the 2015-2016 academic year.

An online application form is available by clicking;

http://www.cdr.fi/news-and-events/integrate-etn-student-application-form

The deadline for applications routed through the above website is March 9th, but Dr welch will still consider applications from exceptional individuals until the end of April. If you wish to apply for this position after March 9th, or if you have any queries regarding the position, please contact Dr Welch directly - mw240@cam.ac.uk .The Welch lab website can be found at: http://www.bioc.cam.ac.uk/people/uto/welch

Please quote reference PH05532 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Curator/ University Lecturer in Vertebrate Palaeontology (Tenure Track Position)

From Jobs at the University of Cambridge. Published on Mar 03, 2015.

We seek to recruit an outstanding scientist to join the staff of the Department and Museum of Zoology at Cambridge. The successful candidate will combine excellence in research with a commitment to teaching at both undergraduate and graduate levels. In addition he/she will have the ability to engage with the work of the Museum in collections development, outreach and public engagement.

We seek a candidate with the ambition and ability to fund and lead a world-class research group. For this post, we are likely to appoint a candidate whose research is collections-based. The appointee will take overall academic responsibility for the vertebrate palaeontology collections, working with professional collections management staff, who will undertake the routine management of the collections.

The selection criteria for this post are:

Essential

An outstanding research record, documented by publication and by the demonstrated ability to attract research funding.

An innovative and focused research agenda in vertebrate palaeontology.

Experience of working with Museum collections, and an engagement with the process of biological and, when appropriate, geological curation.

The training and expertise to contribute broadly to undergraduate teaching in the area of vertebrate evolutionary biology.

Desirable

Curatorial experience in a major research museum.

Taxonomic expertise relating to an area relevant to the Museum's existing collections.

A programme of research that will enhance and develop the collections of the Museum.

Demonstrated excellence in teaching undergraduates and supervising research students.

A track record of commitment to wider responsibilities in a current or previous institution (for example, in research leadership, museum development, or public engagement).

The duties and responsibilities of this post will be:

To conduct research in some area of Vertebrate Evolutionary Biology and Palaeontology.

To teach undergraduate and graduate students in Evolutionary Biology and related disciplines.

To take curatorial responsibility for the vertebrate palaeontology collections.

To promote outreach and public engagement

Appointment will be from 1st Oct 2015, with some possibility for flexibility.

Appointment will be for a probationary period of five years with appointment to the retiring age thereafter, subject to satisfactory performance.

The Department would particularly welcome applications from women as we have an historical imbalance in the number of women holding academic staff positions.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PF05523 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Career Development Fellow

From Jobs at the University of Cambridge. Published on Feb 09, 2015.

Applications are invited for Research Career Development Fellowships in the Sainsbury Laboratory. The positions are open to applicants of any nationality. With the intention of nurturing the next generation of researchers in the field of plant science, the Fellowships provide an opportunity for talented junior investigators to develop their own research programme and become creative leaders in the field.

The Sainsbury Laboratory is a new Research Institute located in central Cambridge, providing an outstanding scientific environment. It has excellent resources and core facilities, with state-of-the-art equipment including growth rooms, glasshouses, microscopy and computing facilities. It provides a collaborative research atmosphere where researchers can take risks in a supportive environment. We are seeking to appoint Career Development Fellows who can both contribute to and benefit from this environment. In particular we are looking for scientists with imaginative research ideas that will contribute to our understanding of plant development, by elucidating the links between genotype and phenotype in any appropriate study system.

Applicants will typically have between 3 and 6 years of postdoctoral experience in a field related to the overall scientific focus of the Laboratory in plant development and its computational modelling. Applicants should be able to provide strong evidence of their potential to develop independent research programmes.

Fellowships are for five years. Successful applicants will receive an initial three years of funding, with extension for a further two years contingent on a successful scientific review and will hold an appointment with the University of Cambridge. Funds include full salary, ranging from £38,511 to £48,743, an additional 30% Gatsby distinction award, benefits and £40,000 p.a. of unrestricted research support. As they develop into independent researchers, Fellows will be encouraged to apply for external funding. Fellows can apply for Research Group Leader positions within the Laboratory at any time.

Further details about the post, guidance on how to apply and information about the Sainsbury Laboratory are available on the Sainsbury Laboratory web site: http://www.slcu.cam.ac.uk/

Applications can be submitted electronically at any time as a single pdf file including a full CV, a research proposal for five years, and the names of at least three referees. Completed applications should be sent by e-mail to enquiries@slcu.cam.ac.uk.

Fixed-term: The funds for this post are available for 5 years.

There is no fixed closing date- applications will be assessed throughout the year.

Please quote reference PT05330 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Career Development Fellow - Computational Modelling of Developmental Systems

From Jobs at the University of Cambridge. Published on Feb 09, 2015.

Applications are invited for Research Career Development Fellowships in the Sainsbury Laboratory. The positions are open to applicants of any nationality. With the intention of nurturing the next generation of interdisciplinary researchers in the field of plant developmental biology, the Fellowships provide an opportunity for talented junior investigators to develop their own research program and become creative leaders in the field. The Sainsbury Laboratory is a new Research Institute, providing an outstanding scientific environment. It has excellent resources and core facilities, with state-of-the-art equipment including high performance computing, growth rooms, glasshouses and microscopy. It provides a collaborative research atmosphere where researchers can take risks in a supportive environment. We are seeking to appoint Career Development Fellows who can both contribute to and benefit from this environment. In particular we are looking for scientists with computational or mathematical modeling expertise and imaginative research ideas that will contribute to our understanding of plant development by elucidating the links between genotype and phenotype. Experience with plant systems is not required. Applications are welcome from researchers wishing to move into plant biology from any other study system.

Applicants will typically have between 3 and 6 years of postdoctoral experience and should be able to provide strong evidence of their potential to develop independent research programs. Fellowships are for five years. Successful applicants will receive an initial three years of funding, with extension for a further two years contingent on a successful scientific review and will hold an appointment with the University of Cambridge. Funds include full salary, ranging from £38,511 to £48,743, an additional 30% Gatsby distinction award, benefits and £40,000 p.a. of unrestricted research support. As they develop into independent researchers, Fellows will be encouraged to apply for external funding. Fellows can apply for Research Group Leader positions within the Laboratory at any time.

Further details about the post, guidance on how to apply and information about the Sainsbury Laboratory are available on the Sainsbury Laboratory web site: http://www.slcu.cam.ac.uk/

Applications can be submitted electronically at any time as a single pdf file including a full CV, a research proposal for five years, and the names of at least three referees. Completed applications should be sent by e-mail to enquiries@slcu.cam.ac.uk.

Fixed-term: The funds for this post are available for 5 years.

There is no fixed closing date - applications will be assessed throughout the year.

Please quote reference PT05341 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.