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Drosophila and Molecular Biology Technician (Part Time, Fixed Term)

From Jobs at the University of Cambridge. Published on May 27, 2016.

We wish to appoint a research technician to join Dr Frank Jiggins' group here in the Department of Genetics. The post holder will work closely with two postdoctoral researchers on an ERC funded project led by Dr Jiggins, on a specific project looking at the genetics and evolution of insects (Drosophila) and their viral pathogens.

The work will involve both working with Drosophila (maintenance, rearing, helping with experiments) and molecular biology (RNA extractions, RT-PCR, quantitative PCR), as well as day-to-day organisation of the lab (ordering, lab up-keep etc).

You should have a GCSE or equivalent at grade C or above in a science subject, along with English and Maths, and an interest in the biological sciences. Experience of working with insects and of basic molecular biology would be an advantage, and previous research laboratory experience is required.

Details of the research in the lab can be found at: http://www.gen.cam.ac.uk/research/Jiggins/index.html

Fixed-term: The funds for this post are available until 31 October 2016 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries should be addressed to Dr Frank Jiggins fmj1001@cam.ac.uk

Please quote reference PC09245 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Head of Development and Publicity[Temporary Cover] (Secondment)

From Jobs at the University of Cambridge. Published on May 26, 2016.

Available until November 2018 due to the secondment of the current role-holder, this is a unique opportunity to work within the Botanic Garden (60%) and the Development and Alumni Relations office (40%).

Three days a week reporting to the Director of the Botanic Garden, the role-holder is responsible for raising funds from non-University sources, and for developing and enhancing the press and public profile of the Garden with the aim of increasing visitor numbers and the profile of the Garden. The role-holder will implement the Garden's annual press and publicity plan and maintain visitor communications within the Garden. The role holder manages gifts into several fundraising income streams, prepares and manages bids to external funders and maintains budgetary and administrative management of successful bids for both restoration projects and for new developments. A member of the Garden's senior management team, the role-holder leads development of the offer and communications for the Friends and Corporate Friends of Cambridge University Botanic Garden.

Two days a week reporting to the Senior Associate Director of Trusts and Foundations at CUDAR as a member of the fundraising team, contributing to the design and execution of the University of Cambridge Museums' major gifts fundraising strategy, of which the Botanic Garden is part. Responsible for implementing a strategy to secure philanthropic support, managing a donor/prospect pool and engaging potential donors effectively, to match funding priorities.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For any questions regarding this role, please contact admin@botanic.cam.ac.uk

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Laboratory Technician (Part Time, Fixed Term)

From Jobs at the University of Cambridge. Published on May 26, 2016.

Would you like to join a young and dynamic research team investigating the mechanics of nervous system development and pathology? The team is led by Dr Kristian Franze, see: http://www.pdn.cam.ac.uk/directory/kristian-franze

You will be involved in all aspects of technical support for the research laboratory but in particular cell culture and the production of polyacrylamide gels. We are looking for a team player with good IT and analytical skills.

You should have GCSE English and Mathematics, plus A level (or equivalent) in a science subject as well as a sound background and experience in biological scientific research with experience in the use of molecular biology techniques and equipment.

The post is 50% of full-time. Working 4 - 5 days a week would be preferred but this is negotiable.

Fixed-term: The funds for this post are available until 31 May 2017 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please complete the online application as fully as possible.

The closing date for applications is midnight on Wednesday 15 June 2016.

Please quote reference PM09246 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Administrative Assistant

From Jobs at the University of Cambridge. Published on May 25, 2016.

Applications are invited for the full time post of Administrative Assistant, based within the Administration Office of the Department of Pathology.

The administration office team consists of three members of staff overseen by the Administration Manager. As well as providing a secretarial support service to the Head of Department and the two Departmental Secretaries, the role supports the wider departmental administrative functions including human resources, staff review and development, job advertising and recruitment, security card issue, examination administration and reception cover.

Applicants should be educated to GCSE level or equivalent (including English), be IT literate with good working knowledge of MS Office and knowledge of web-based administrative systems or a willingness to acquire them.

The ability to communicate both verbally and in writing is essential, as is the ability to multi-task, manage your own time, work on own initiative whilst being a team member and behave in a professional manner at all times. Previous experience of reception work and knowledge of University administrative systems and procedures would be an advantage.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK09231 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant (Fixed Term)

From Jobs at the University of Cambridge. Published on May 25, 2016.

University of Cambridge Department of Veterinary Medicine West Cambridge Site / Animal and Plant Health Agency Weybridge Surrey Research Assistant

Fixed-term: The funds for this post are available for 24 months in the first instance.

Applications are invited for a Research Assistant, funded by BBSRC, on a project aiming to prepare genomic material to whole genome sequence several thousand isolates of Mycobacterium bovis from cattle and badgers. The project will involve partners at Cambridge, APHA and Wellcome Trust Sanger Institute, led by Professor James Wood. The role will be based at the Animal and Plant Health Agency (APHA), Weybridge, Surrey.

The role-holder will work closely with the APHA team, led by Dr Smith, to locate and culture M. bovis isolates and prepare genomic DNA from this material for sending for sequencing at Wellcome Trust Sanger Institute.

Applicants should be educated to first degree level, in a biological science or a related discipline, and should have a good knowledge of routine molecular genetics, and sterile laboratory procedures Experience of bacterial cultivation and PCR would be an advantage. The candidate must value teamwork and collaboration, have good administrative and interpersonal skills, with the ability to work as part of a team and be computer literate.

Informal enquiries should be directed to Julie Ingham Assistant Secretary HR ji217@cam.ac.uk

Closing date 26th June 2016

Interviews will be held on 11th July 2016 and will take place at the Animal and Plant Health Agency, Weybridge, Surrey.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should submit a CHRIS/6, CV, covering letter outlining suitability for the role and contact details for two references. Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application. Further particulars for the role and information about the Department www.vet.cam.ac.uk

Please quote reference PP09239 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate

From Jobs at the University of Cambridge. Published on May 23, 2016.

Applications are invited for a full time Research Assistant/Associate position in the laboratory of Dr Gillian Fraser, based at the Department of Pathology, central Cambridge, to investigate bacterial flagellum assembly.

Our Molecular, Structural and Cellular Microbiology unit applies biochemical, molecular and structural biology approaches to understand cell-surface assembly of macromolecular nanomachines that enable cell motility, virulence protein export and multidrug efflux in pathogenic bacteria. For details, see: Nature (2013) 504:287-290; PNAS (2006) 103:17474-9, ibid (2011) 108: 2112-7, ibid (2009) 106: 7173-8, ibid (2007)104:4612-7; http://www.path.cam.ac.uk/directory/research-themes/microbiology.

Candidates must have, or be close to obtaining, a PhD in a relevant field and a strong background in protein biochemistry, biophysics and structural biology, or in fluorescence microscopy and microfluidics. Experience in molecular biology or microbiology is also desirable.

Ability to work both as part of a team and independently, coupled with excellent communication, organizational and problem solving skills are required. The duties/responsibilities of this post, as outlined in the further information documents, include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures.

Where the successful applicant does not yet have a PhD, he/she will normally be under-appointed as a Research Assistant in a Research Associate post (on the understanding that he/she will be appointed as a Research Associate upon successful completion of his/her PhD). The higher Research Associate salary should be backdated to the submission date of their thesis.

Specific enquiries and requests for more details of the project are encouraged and should be made to Gillian Fraser at gmf25@cam.ac.uk

Fixed-term: The funds for this post are available until 21st June 2018 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK09203 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

NERC case studentship (Fixed Term)

From Jobs at the University of Cambridge. Published on May 23, 2016.

Development of image analysis techniques to enable tropical rainforests to be monitored from aircraft.

Project Description Many tropical countries are committed to restoring large tracts of their forest, which is good news for conservation after many decades of unprecedented forest loss across the tropics. We are looking for an exceptional student with strong interests in image analysis. Working with mathematicians and remote sensing experts from the University of Cambridge, they will develop innovative tools for monitoring the quality of forests using basic imagery collected by UAVs. They will work closely with staff at the Royal Society for the Protection of Birds (RSPB), which co-manages two reserves in the tropics, to deliver products that are useful for tropical forest conservation.

Candidates should have been awarded, or expect to achieve, at least a 2.1 in their honours degree. The position is particularly well suited to mathematicians, engineers and computer scientists interested in image analysis, although biologists with strong quantitative skills are welcome to apply. Interest in sensors and UAVs is desirable, although not essential as training will be given. Having a fundable belief in the value of nature conservation is important from a motivational perspective. The position is fully supported by a NERC industrial case studentship, and is a collaboration between the University of Cambridge and the Royal Society for the Protection of Birds (RSPB). As an industrial case student, the applicant would spend several months working with the RSPB and their stipend would be supplemented by £1000/year. Only UK residents are eligible to receive a student stipend from the Natural Environment Research Council. http://www.rcuk.ac.uk/documents/publications/traininggrantguidance-pdf/

Applicants should email all David Coomes (dac18@cam.ac.uk) and Tom Swinfield (twswinfield@gmail.com) with the following: 1. A cover letter, outlining your interest in this research area and any relevant experience that you have in the field. Please explain what makes you suitable for this position. 2. Their CV. Please include "NERC Case Studentship" in the subject line. We welcome informal enquiries should you require further information.

Please quote reference PD09209 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate: Computational biologist (Fixed Term)

From Jobs at the University of Cambridge. Published on May 23, 2016.

Two postdoctoral research posts are available to work on an ERC funded project 'SynthHotSpot' in the laboratory of Dr Ian Henderson in the Department of Plant Sciences at the University of Cambridge. This project seeks to understand and control recombination in plant genomes. This work has basic relevance for genome function and evolution and also has applied impact in the context of crop breeding. The Department of Plant Sciences is a world-class centre for the study of plant biology, equipped with excellent growth facilities and laboratories.

This postholder will perform bioinformatics and statistical analysis of genomic and genetic data generated in the project. This will involve testing hypotheses using functional genomics data generated in our laboratory. Development of suitable computational methods to best answer these questions is expected. Confident knowledge of statistical approaches and one or more core programming languages (R, phyton, perl or similar) are essential. Applicants should ideally have experience using next generation sequencing data for genomics analysis. The applicant should have excellent organizational skills, drive and the ability for independent and critical thinking. Good communication skills and the ability to work in a team are also essential. A Ph.D in a relevant area of computer science or bioinformatics is required. The start date for the project is 1st October 2016. Fixed-term: The funds for this post are available for 3 years in the first instance.

REFERENCES

NE Yelina, C Lambing, TJ Hardcastle, X Zhao, B Santos, IR Henderson (2015) DNA methylation epigenetically silences crossover hot spots and controls chromosomal domains of meiotic recombination in Arabidopsis. Genes Dev 29, 2183-2202

K Choi, IR Henderson (2015) Meiotic recombination hotspots¿a comparative view. The Plant Journal 83 (1), 52-61

PA Ziolkowski, LE Berchowitz, C Lambing, NE Yelina, X Zhao, KA Kelly, ... (2013) Juxtaposition of heterozygous and homozygous regions causes reciprocal crossover remodelling via interference during Arabidopsis meiosis. Elife 4, e03708

NE Yelina, PA Ziolkowski, N Miller, X Zhao, KA Kelly, DF Muñoz, DJ Mann, ... (2013) High-throughput analysis of meiotic crossover frequency and interference via flow cytometry of fluorescent pollen in Arabidopsis thaliana Nature protocols 8 (11), 2119-2134

K Choi, X Zhao, KA Kelly, O Venn, JD Higgins, NE Yelina, TJ Hardcastle, ... (2013) Arabidopsis meiotic crossover hot spots overlap with H2A. Z nucleosomes at gene promoters Nature genetics 45 (11), 1327-1336

NE Yelina, K Choi, L Chelysheva, M Macaulay, B De Snoo, E Wijnker, ... (2012) Epigenetic remodeling of meiotic crossover frequency in Arabidopsis thaliana DNA methyltransferase mutants PLoS Genet 8 (8), e1002844

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For more information contact Ian Henderson (irh25@cam.ac.uk)

Please quote reference PD09208 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate: Experimental geneticist (Fixed Term)

From Jobs at the University of Cambridge. Published on May 23, 2016.

Two postdoctoral research posts are available to work on an ERC funded project 'SynthHotSpot' in the laboratory of Dr Ian Henderson in the Department of Plant Sciences at the University of Cambridge. This project seeks to understand and control recombination in plant genomes. This work has basic relevance for genome function and evolution and also has applied impact in the context of crop breeding. The Department of Plant Sciences is a world-class centre for the study of plant biology, equipped with excellent growth facilities and laboratories.

For this vacancy the postholder will perform genetics and genomics experiments in order to understand and control recombination, using Arabidopsis thaliana as a model species. The applicant should ideally have experience with model system genetics, in plant or non-plant species. Experience in molecular biology, genomics or quantitative genetics are desirable. A deep interest in the basic mechanisms controlling genome function and evolution are essential. The applicant should have excellent organizational skills, drive and the ability for independent and critical thinking. Familiarity with a programming language is an advantage (R, phyton, perl or similar). A Ph.D in a relevant area of the biosciences is required. Good communication skills and the ability to work in a team are essential. The start date for the project is 1st October 2016.

Fixed-term: The funds for this post are available for 3 years in the first instance.

REFERENCES

NE Yelina, C Lambing, TJ Hardcastle, X Zhao, B Santos, IR Henderson (2015) DNA methylation epigenetically silences crossover hot spots and controls chromosomal domains of meiotic recombination in Arabidopsis. Genes Dev 29, 2183-2202

K Choi, IR Henderson (2015) Meiotic recombination hotspots¿a comparative view. The Plant Journal 83 (1), 52-61

PA Ziolkowski, LE Berchowitz, C Lambing, NE Yelina, X Zhao, KA Kelly, ... (2013) Juxtaposition of heterozygous and homozygous regions causes reciprocal crossover remodelling via interference during Arabidopsis meiosis. Elife 4, e03708

NE Yelina, PA Ziolkowski, N Miller, X Zhao, KA Kelly, DF Muñoz, DJ Mann, ... (2013) High-throughput analysis of meiotic crossover frequency and interference via flow cytometry of fluorescent pollen in Arabidopsis thaliana Nature protocols 8 (11), 2119-2134

K Choi, X Zhao, KA Kelly, O Venn, JD Higgins, NE Yelina, TJ Hardcastle, ... (2013) Arabidopsis meiotic crossover hot spots overlap with H2A. Z nucleosomes at gene promoters Nature genetics 45 (11), 1327-1336

NE Yelina, K Choi, L Chelysheva, M Macaulay, B De Snoo, E Wijnker, ... (2012) Epigenetic remodeling of meiotic crossover frequency in Arabidopsis thaliana DNA methyltransferase mutants PLoS Genet 8 (8), e1002844

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For more information contact Ian Henderson (irh25@cam.ac.uk)

Please quote reference PD09207 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Postdoctoral Research Associate - Informatician (Fixed Term)

From Jobs at the University of Cambridge. Published on May 20, 2016.

Proteomics/Mass Spectrometry, Department of Biochemistry, University of Cambridge, Central Cambridge.

We are seeking to employ an enthusiastic postdoctoral scientist to join the Cambridge Centre for Proteomics, at the University of Cambridge, led by Professor Kathryn Lilley. The successful candidate will work on a project funded by a joint Wellcome Trust Investigator award to Professor Anne Willis (MRC Toxicology Unit, University of Leicester) and Professor Kathryn Lilley. The project is entitled "Transcription, Trafficking, Translation: dissecting the spatiotemporal mechanisms underlying localised protein synthesis".

It is now widely acknowledged that mRNA is spatially organised such that its translation frequently occurs in the vicinity where the corresponding protein product adopts its function. This phenomenon has been studied extensively in specialised cells, however, recent research has suggested that spatial restriction of mRNA storage and translation is much more widespread.

The aims of this project are to define where translation of mRNA takes place in the cell, how this is regulated by protein binding partners and sequence motifs and how this changes upon cellular perturbation.

We are building a team of RNA biologists, mass spectrometrists, and informaticians to help tackle these challenging aims.

This post involves the development of machine learning approaches to interrogate spatial data from proteomics and transcriptomics experiments. Creation of on-line resources to allow public accessibility of data. All post-holders will be expected to assist in the creation of a series of workshops and public outreach events to disseminate methods, data and concepts to the wider community.

The ideal applicant will have (or in the final stages of completing) a PhD in computational biology with a background in dealing with large data sets generated from proteomics and/or next generation sequencing. A knowledge of machine learning tools and the R programming language is essential.

The following recent publication has direct relevance to this project: 1. A draft map of the mouse pluripotent stem cell spatial proteome. Christoforou et al Nature Commun. 20167:8992. doi:10.1038/ncomms9992 2. Learning from Heterogeneous Data Sources: An Application in Spatial Proteomics. Breckels et al PLoS Comput Biol. 2016 May 13;12(5):e1004920. doi: 10.1371/journal.pcbi.1004920

For more information please visit: http://www.bioc.cam.ac.uk/people/uto/lilley and http://tox.mrc.ac.uk/

Fixed-term: The funds for this post are available for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries can be made to Professor Lilley - k.s.lilley@bioc.cam.ac.uk

Please quote reference PH09168 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Postdoctoral Research Associate - Proteomics/Mass Spectrometrist (Fixed Term)

From Jobs at the University of Cambridge. Published on May 20, 2016.

Proteomics/Mass Spectrometry, Department of Biochemistry, University of Cambridge, Central Cambridge.

We are seeking to employ an enthusiastic postdoctoral scientist to join the Cambridge Centre for Proteomics at the University of Cambridge, led by Professor Kathryn Lilley. The successful candidate will work on a project funded by a joint Wellcome Trust Investigator award to Professor Anne Willis (MRC Toxicology Unit, University of Leicester) and Professor Lilley. The project is entitled "Transcription, Trafficking, Translation: dissecting the spatiotemporal mechanisms underlying localised protein synthesis".

It is now widely acknowledged that mRNA is spatially organised such that its translation frequently occurs in the vicinity where the corresponding protein product adopts its function. This phenomenon has been studied extensively in specialised cells, however, recent research has suggested that spatial restriction of mRNA storage and translation is much more widespread.

The aims of this project are to define where translation of mRNA takes place in the cell, how this is regulated by protein binding partners and sequence motifs and how this changes upon cellular perturbation.

We are building a team of RNA biologists, mass spectrometrists, and informaticians to help tackle these challenging aims.

This post involves the development and application of spatial proteomics methods including hyperLOPIT (1) and proximity tagging approaches to make detailed maps of the subcellular proteome of various mammalian cell lines, maps of location of RNA binding proteins, and how these change upon cell perturbation such as insulin stimulation

The ideal applicant will have (or in the final stages of completing) a PhD in biological sciences with expertise in proteomics, mass spectrometry and cell biology. Some knowledge of informatics is also desired.

The following recent publication has direct relevance to this project: 1. A draft map of the mouse pluripotent stem cell spatial proteome. Christoforou et al Nat Commun. 20167:8992. doi: 10.1038/ncomms9992

For more information please visit: http://www.bioc.cam.ac.uk/people/uto/lilley and http://tox.mrc.ac.uk/

Fixed-term: The funds for this post are available for 5 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries can be made to Professor Lilley - k.s.lilley@bioc.cam.ac.uk

Please quote reference PH09167 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Postdoctoral Research Associate - RNA Biologist/Proteomics (Fixed Term)

From Jobs at the University of Cambridge. Published on May 20, 2016.

Proteomics/Mass Spectrometry, Department of Biochemistry, University of Cambridge, Central Cambridge.

We are seeking to employ an enthusiastic postdoctoral scientist to join the Cambridge Centre for Proteomics at the University of Cambridge, led by Professor Kathryn Lilley. The successful candidate will work on a project funded by a joint Wellcome Trust Investigator award to Professor Anne Willis (MRC Toxicology Unit, University of Leicester) and Professor Lilley. The project is entitled "Transcription, Trafficking, Translation: dissecting the spatiotemporal mechanisms underlying localised protein synthesis".

It is now widely acknowledged that mRNA is spatially organised such that its translation frequently occurs in the vicinity where the corresponding protein product adopts its function. This phenomenon has been studied extensively in specialised cells, however, recent research has suggested that spatial restriction of mRNA storage and translation is much more widespread.

The aims of this project are to define where translation of mRNA takes place in the cell, how this is regulated by protein binding partners and sequence motifs and how this changes upon cellular perturbation.

We are building a team of RNA biologists, mass spectrometrists, and informaticians to help tackle these challenging aims.

This post involves the creation of RNA correlation profiling methods, including sub cellular fractionation, cross linking of RNA to binding proteins and next generation sequencing.

The ideal applicant will have (or in the final stages of completing) a PhD in Biological Sciences with expertise in RNA biology, translation, cell biology, cell fractionation and next generation sequencing methods. Some knowledge of mass spectrometry would also be advantageous, along with an interest in informatics and the handling of large datasets.

The following recent publication has direct relevance to this project: 1. A draft map of the mouse pluripotent stem cell spatial proteome. Christoforou et al Nat Commun. 20167:8992. doi: 10.1038/ncomms9992

For more information please visit: http://www.bioc.cam.ac.uk/people/uto/lilley and http://tox.mrc.ac.uk/

Fixed-term: The funds for this post are available for 5 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries can be made to Professor Lilley - k.s.lilley@bioc.cam.ac.uk

Please quote reference PH09166 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate

From Jobs at the University of Cambridge. Published on May 19, 2016.

A postdoctoral position is available to work in the research group of Professor Daniel St Johnston (see http://www.gurdon.cam.ac.uk/research/stjohnston) at the Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge.

The project will focus on epithelial polarity in the adult Drosophila midgut. Candidates should have a PhD in Biological Sciences or be close to a completion of their degree, and must be highly motivated with prior graduate experience in cell biology. Experience of live imaging and cytoskeletal organization is essential. Expertise in the analysis of cell shape and structure and the functions of molecular motors would be an advantage.

Limited funding: The funds for this post are available until 30 September 2017 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please upload a CV, a brief statement of your research interests and cover letter with your application. Please contact Vanessa Stefanak if you require further information at v.stefanak@gurdon.cam.ac.uk or telephone 01223334088. Please quote reference PR09188 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working and funds for returning carers and other family-friendly schemes.

University Lecturer/ University Senior Lecturer in Veterinary Education:Curriculum Innovation and Development

From Jobs at the University of Cambridge. Published on May 19, 2016.

The Department wishes to appoint with effect from 1 September 2016. Appointment will be made at the level of University Lecturer or University Senior Lecturer, according to qualifications and experience.

This is a permanent full-time University Teaching Officer (academic) role.

The role holder will support the Head of Department by working as part of the education and teaching team to ensure delivery of excellence in teaching to clinical veterinary students; to design initiatives and overall approaches to address evolving needs for innovation in veterinary education; to implement initiatives approved by the Department's Teaching Strategy Committee; to contribute directly to teaching on the clinical veterinary course in large animal clinical and para-clinical areas; and to embed the principles of and equality and diversity and Athena SWAN in the veterinary curriculum and related academic processes.

Essential criteria:

-Be a member of the Royal College of Veterinary Surgeons, or hold a veterinary degree qualifying her/him for membership.

-Have a PhD or doctoral level degree in a relevant area.

-A track record of research and research publication in a relevant area.

-Have significant experience in veterinary curriculum teaching and development.

-Have large animal clinical and teaching experience.

For informal enquiries about the position, please contact Natalie Wills on nw366@cam.ac.uk

Department website: www.vet.cam.ac.uk

Further information about the role: click on link below

Please ensure that you upload your Curriculum Vitae (CV) a covering letter, and a research publication list in the upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Closing date for applications: 19 June 2016

Interview date: 28 June 2016

Please quote reference PP09180 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Electron Microscopist - Cambridge Advanced Imaging Centre (Fixed Term)

From Jobs at the University of Cambridge. Published on May 19, 2016.

We are looking for an Electron Microscopist to manage CAIC's electron microscopy facility and to further develop the current provision as a state-of the-art facility for the School of Biological Sciences and other members of the scientific community in Cambridge, see http://caic.bio.cam.ac.uk/

At present CAIC has an FEI Verios 460 SEM, Tecnai G2 TEM and associated sample preparation equipment. You will be responsible for the delivery of a professional and comprehensive EM service with particular emphasis on operational management and cost-recovery. The services provided include sample preparation, consultation, imaging, and training. You will also be responsible for maintaining a productive laboratory environment, including management of health and safety.

You should have a PhD (or equivalent level qualification) in chemistry or a physical science. You will also have significant experience with electron microscopy and related techniques such as EDX, cryo methods and their implementation in biology and biomaterials applications. You will have excellent analytical, problem-solving and interpersonal skills and be able to work independently at the highest level.

Significant experience in a research environment is essential.

For enquiries please contact Dr Kevin O'Holleran ko311@cam.ac.uk

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. If you upload any additional documents, which have not been requested, we will not be able to consider these as part of your application.

The closing date for applications is midnight on Tuesday 21 June 2016.

Please quote reference PM09182 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on May 19, 2016.

Fixed-term: The funds for this post are available for up to 1 year in the first instance.

Applications are invited for an experienced and enthusiastic cognitive neuroscientist/neuroimagery to work on an ERC grant on language processing. The focus will be on investigating how listeners understand speech, using MEG neuroimaging and statistical language modelling techniques.

The applicant will join the Centre for Speech, Language and the Brain, an inter disciplinary team led by Professor L.K. Tyler. The Centre has access to a research-dedicated 3T Siemens MR scanner, and EEG and MEG facilities. We currently use a variety of analysis methods on MEG data-sets, and in particular multivariate analysis methods such as Representational Similarity Analyses.

Applicants should have a PhD (or equivalent) with excellent computer programming (especially MATLAB and/or Python) and statistical skills, experience of MEG analyses, particularly in using multivariate neuroimaging methods for MEG data and MEG source localization methods. Applicants should have experience in research on spoken language processing (neurobiology of language and/or statistical language modelling). Given the nature of the research, candidates should be native English speakers or fully fluent in English.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PJ09179 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Senior Accounts Clerk (Fixed Term) (INTERNAL APPLICANTS ONLY)

From Jobs at the University of Cambridge. Published on May 18, 2016.

**Internal Applicants Only

The Sainsbury Laboratory is a new research Institute sited within the University Botanic Gardens which focuses on Plant Developmental Biology and computational modelling of plant development. The Institute currently has about 120 researchers and 24 support staff with over £10m p.a. of grant activity and is still growing rapidly.

Reporting directly to the Finance Manager, the post holder will provide a largely autonomous accounts administrative service within the department to include accounts payable, accounts receivable, general ledger, research grants, purchasing, and stores inventory procedures. A good understanding of transaction processes is therefore required.

Candidates should ideally be educated to A-level standard or equivalent, to include GCSE English and Mathematics and have a formal qualification in accounting e.g. AAT Level 2. Previous experience working in a busy academic accounts office would be an advantage, as would a working knowledge of the Cambridge University Finance System, or experience of using other Oracle-based accounting packages.

The successful candidate will have excellent interpersonal, communication and organisational skills, with a positive, service-oriented attitude and be highly competent in standard Microsoft Office software and email packages. They will be able to work independently as well as in a team and have a pro-active approach to problem solving. Attention to detail, a high level of accuracy and effective time management are essential.

The Laboratory provides a welcoming and collaborative environment with a wide-range of family-friendly benefits and development opportunities and the University also supports staff through a range of flexible working arrangements. More about the Sainsbury Laboratory can be found at: http://www.slcu.cam.ac.uk/.

The post is full time and available immediately. Fixed-term: The funds for this post are available for 1 year in the first instance. Applications are invited for either a fixed-term contract or a secondment opportunity.

If you have any questions about this vacancy or the application process, please email enquiries@slcu.cam.ac.uk

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within three weeks of the closing date, please consider your application as unsuccessful on this occasion.

Please quote reference PT09175 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Post-doctoral Research Associate in Ultrahigh-throughput Exploration of Metagenomic Libraries (Fixed Term)

From Jobs at the University of Cambridge. Published on May 16, 2016.

A postdoctoral position is available for 12 months (with a possibility of extension) from 1 August 2016 (or later) to work with Florian Hollfelder on ultrahigh-throughput exploration of metagenomics libraries. Metagenomes comprise enormous reservoirs coding for proteins with useful activities, but harvesting this potential is difficult, because useful candidates are rare and hidden in an overwhelming majority of irrelevant genes. Traditionally screening campaigns of metagenomic libraries thus have required massive capital-expenditure for robotic systems and much manpower, making them expensive, slow and available to very few users.

We have just shown (Colin et al. Nature Communications 2015, 6:10008. doi: 10.1038/ncomms10008) that exploration and exploitation of the metagenome is accelerated and made more successful by ultrahigh-throughput screening in picoliter droplets: allowing throughput of tens of millions of assays per hour, at dramatically lower cost (and work!) per assay. We now want to use this platform technology to identify enzymes for biosynthesis of therapeutic small molecules, for green bioenergy conversion, bioremediation, food chemistry and other industrial applications. The postdoc project involves establishment of suitable assays for these tasks in microdroplet format, building environmental metagenomics libraries and looking for new catalysts that are then characterised mechanistically and structurally.

Candidates with a background (and published track record) in protein engineering, mechanistic enzymology, organic synthesis and microfluidic engineering are highly desirable. Candidates must hold (or be in the final stages of completing) a PhD in a relevant discipline.

The work is part of the EU Project 'Metafluidics' that involves collaborations with companies and academic groups in Spain, Denmark, Norway, France, Portugal and the UK.

Fixed-term: The funds for this post are available for 1 year in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries can be made to Dr Florian Hollfelder -fh111@cam.ac.uk

Please quote reference PH09142 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Senior Histology Technician (Part Time)

From Jobs at the University of Cambridge. Published on May 16, 2016.

We have an exciting part time opportunity for a Senior Histology Technician to assist in the running of the Histology Laboratory that serves the needs of the research groups of the Department, the Queen's Veterinary School Hospital, Cambridge Equine Hospital, Cambridge Farm Animal Services, and external sources. This role is for 14 hours a week, Monday and Tuesday 08:45am - 16:45pm with one hour for lunch. We are looking for someone to join the team from 1st July or as soon as possible after that date.

Applicants should be educated to GCSE standard and have Grade C or above in English, Maths and one Science subject. Experience of all routine histological preparation procedures, including tissue processing and sectioning, H&E and specialist histochemical staining techniques and immunohistochemistry is essential. An understanding of in-situ hybridisation and other molecular procedures are desirable. The post holder will use specialist knowledge and techniques and will require excellent observational skills and the ability to remain focussed for long periods of time.

Applicants should also be able to demonstrate familiarity of health and safety issues within a laboratory setting, a strong customer focus and accurate record keeping skills. It is essential that applicants should also be able to demonstrate good organisational skills and the ability to prioritise their own workload and be able to work on their own initiative.

For informal enquiries please contact Natalie Wills on nw366@cam.ac.uk.

Further particulars for the role and information about the Department www.vet.cam.ac.uk.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Closing Date: 19 June 2016

Interviews will be held on 5 July 2016

Please quote reference PP09154 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Postdoctoral Research Associate in Microbial Membrane Proteomics (Fixed Term)

From Jobs at the University of Cambridge. Published on May 12, 2016.

DeTOX - Productive whole cell biocatalysis by engineering resistance to toxic products and substrates

Proteomics/Mass Spectrometry, Department of Biochemistry, University of Cambridge, Cambridge.

This post represents an outstanding opportunity for a protein biochemist to join a multi-disciplinary team working on a flagship BBSRC Industrial Biocatalyst Award involving research groups in York, Sheffield, Nottingham and Cambridge along with five commercial partners. Product yields of many important industrial fermentations are limited by chemical (product) toxicity and this consortium aims to gather extensive fundamental information using a range of cutting edge 'omic's-based techniques to learn how accumulation of these chemicals leads to severe cell stress and eventually death. The project ("DeTox") will also engineer a variety of solutions into these strains to produce more tolerant versions. This will include engineering increased resistance to small molecules in the industrially relevant bacteria, E. coli & solventogenic Clostridia.

As part of this consortium, the Lilley group is keen to employ a post doctoral researcher to work as part of this project with the aim of characterising bacterial membrane proteins and how their abundance, protein stability, and membrane location correlates with adaptation to engineered production of small molecules. The project will make use of cutting edge proteomics techniques and mass spectrometry approaches developed in the Lilley lab. including spatial proteomics to map proteins to bacterial membranes and protein complexes. (HyperLOPIT- Nature Communications (2016) doi: 10.1038/ncomms9992).

The ideal applicant will have a PhD in a biological science and ideally expertise in protein chemistry, quantitative proteomics, mass spectrometry and microbiology.

The post will involve very close interaction with the other groups within the DeTOX consortium, and involve some limited travel to the other sites, training in fermentation processes, and informatics tools (EchoBASE -Bioinformatics. 2009 Jan 15;25(2):163-6. doi: 10.1093/bioinformatics/btn596.)

Fixed-term: The funds for this post are available for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries can be made to Kathryn Lilley - k.s.lilley@bioc.cam.ac.uk

Please quote reference PH09128 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Client Services Administrator (Fixed Term)

From Jobs at the University of Cambridge. Published on May 12, 2016.

The Queen's Veterinary School Hospital is looking for a pro-active, adaptable team player to work in the Reception area of both the Small and Large Animal sections as part of the Hospital Administration Team. This is a full time position working an early and late rota (8.15am - 16:45pm and 9.15am - 17.45pm) with one hour for lunch each day, some flexibility is required. You will be expected to work in the large animal and small animal reception areas.

You will be the first point of contact for our clients, therefore a friendly manner, combined with excellent communication skills are essential. You will be responsible for receiving incoming calls and faxes, billing clients and taking payments, booking appointments, liaising with clients, referral practices, clinicians, nurses and students and therefore knowledge of medical terminology would be advantageous.

The ability to plan and prioritise your own workload is essential along with being able to work within a team environment.

You should have a good knowledge of IT systems and should be numerate, accurate and have an eye for detail. You will be educated to 'A' level standard or have experience in a similar working environment.

For informal enquiries please contact Natalie Wills on nw366@cam.ac.uk

Fixed-term: The funds for this post are available for 3 years in the first instance.

Further particulars for the role and information about the Department www.vet.cam.ac.uk.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Closing Date: 5 June 2016

Interviews will be held: 16 June 2016

Please quote reference PP09130 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Client Services Administrator (Part Time, Fixed Term)

From Jobs at the University of Cambridge. Published on May 12, 2016.

The Queen's Veterinary School Hospital is looking for a pro-active, adaptable team player to work in the Reception area of both the Small and Large Animal sections as part of the Hospital Administration Team. This is a part time position working 15 hours per week on an early and late rota (8.15am - 16:45pm and 9.15am - 17.45pm) Monday and Tuesday with one hour for lunch each day, some flexibility is required. You will be expected to work in the large animal and small animal reception areas.

You will be the first point of contact for our clients, therefore a friendly manner, combined with excellent communication skills are essential. You will be responsible for receiving incoming calls and faxes, billing clients and taking payments, booking appointments, liaising with clients, referral practices, clinicians, nurses and students and therefore knowledge of medical terminology would be advantageous.

The ability to plan and prioritise your own workload is essential along with being able to work within a team environment.

You should have a good knowledge of IT systems and should be numerate, accurate and have an eye for detail. You will be educated to 'A' level standard or have experience in a similar working environment.

For informal enquiries please contact Natalie Wills on nw366@cam.ac.uk

Further particulars for the role and information about the Department www.vet.cam.ac.uk.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Closing Date: 5 June 2016

Interviews will be held: 16 June 2016

Please quote reference PP09131 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Visitor Services Assistant (Part Time)

From Jobs at the University of Cambridge. Published on May 11, 2016.

We are looking to recruit a Visitor Services Assistant 32 hours per week within the Visitor Services Team of the Botanic Garden, Friday to Monday including all Bank Holidays that fall on those days and weekends.

Responsible to the Head of Visitor Services, the Visitor Services Assistant team provide excellent front of house service. They welcome visitors, staff the reception area/Enquiry point and ticket offices, sell publications and membership, patrol the Garden to ensure the safety and security of its collections, buildings and visitors, ensure public areas are clean and fully stocked, and assist in setting up rooms for events and activities. Includes working outside and undertaking practical tasks in a wide variety of weather conditions.

The candidate should be educated to at least GCSE level standard or equivalent (including English and Mathematics) and be committed to providing first-class visitor service. Previous experience of cash-handling, cash tills and computers, including e-mail correspondence is essential. Good telephone manner and the ability to deal with people at all levels required.

Interviews week commencing 27 June 2016

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For any questions relating to this position, please contact admin@botanic.cam.ac.uk

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on May 11, 2016.

Applications are invited for a Post-doctoral Research Associate position in the group of Professor Yrjo Helariutta at the Sainsbury Laboratory Cambridge University, to investigate root procambial development in plants.

The research group studies the importance of two phytohormones, cytokinins and auxin, in controlling procambial patterning. Current research is showing that the two hormones are interacting in multiple ways, including signal transduction and transport, as well as being linked to the transcriptional downstream programs. The Helariutta group is using a combination of genetic and molecular screens to understand these regulatory networks. The successful candidate would work closely with the group to take an active part in this research area and would be provided with horticultural and technical support.

Candidates must have a PhD in plant biology, plant biotechnology or related field. Expertise in plant hormonal biology, cell biology, transporter biology and plant developmental biology in Arabidopsis is essential. Candidates must also have advanced knowledge of standard molecular cloning, fluorescent microscopy techniques and micro-grafting. Experience in plant cell transformation, co-immunoprecipitation and computer-based sequence analysis is desirable.

The successful candidate will be fully involved in the basic research whilst also writing up their research work for presentation and publication. The post holder may be required to assist in the supervision of student projects, provide instructions to students and deliver seminars relating to their research area.

Good communication skills are essential as the post holder will need to work well in a team and collaborate with other researchers in the Institute. Candidates would ideally have published or submitted papers in this area.

The Laboratory provides a welcoming and collaborative environment with a wide-range of family friendly benefits and development opportunities. More about the Sainsbury Laboratory, further information for the role and details of what the University offers to employees, can be found at: http://www.slcu.cam.ac.uk/.

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload a copy of your full CV with publications list, a supporting statement and contact information of three referees.

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within three weeks of the closing date, please consider your application as unsuccessful on this occasion.

Please quote reference PT09115 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on May 09, 2016.

We are looking for a postdoctoral researcher to work on how host-parasite coevolution can result in changes in host susceptibility to RNA viruses. The work will be carried out in the lab of Dr Frank Jiggins (University of Cambridge) in collaboration with Dr Ben Longdon (University of Exeter).

Working with several species of Drosophila and a group of naturally occurring viruses (sigma viruses), you will examine whether coevolution between hosts and parasites increases genetic variation in susceptibility to infection. The project will examine the genetic basis of disease susceptibility to further our understanding of how resistance to parasites evolves.

The work will suit a researcher who holds, or is about to be awarded, a PhD in evolutionary biology. Desirable skills include a familiarity with animal/insect husbandry, experience with molecular techniques, ideally including DNA/RNA extractions, PCR and qRT-PCR and experience of data analysis in R. Experience in host-pathogen coevolution, evolutionary biology or evolutionary genetics will be beneficial.

Fixed-term: The funds for this post are available until 10 May 2018 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please contact Frank Jiggins (fmj1001@cam.ac.uk) and or Ben Longdon (b.longdon@gen.cam.ac.uk) for further information about the project.

Please quote reference PC08606 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Graduate Research Assistant in Innate Immunity

From Jobs at the University of Cambridge. Published on May 05, 2016.

A graduate research assistant position is available funded by the Wellcome Trust to work in the laboratory of Dr Brian Ferguson, based in the Department of Pathology, University of Cambridge, central Cambridge, which studies the innate immune response to infection. This position is available from October 2016 for 2 years and the successful candidate will join a research team studying the role of DNA repair machinery in the innate immune response to DNA viruses.

Applicants should have a strong academic record and hold an upper second class or first class degree, or equivalent, in biological sciences or medicine. Prior experience with cell signalling research and immunology or virology would be advantageous. The project will involve the use of mammalian cell culture, CRISPR genome editing, high resolution imaging and proteomics, so familiarity with one or more of these techniques will be viewed favourably. The ability to work both independently and as part of a team, coupled with excellent communication, organizational and problem solving skills are required. Other duties/responsibilities as outlined in the Further Information document include undertaking basic research, conduct literature and database searches, write up results of own research, contribute to the production of research reports and publications, present information on research progress and outcomes to bodies supervising research.

Informal enquiries may be made to Dr B Ferguson at bf234@cam.ac.uk

Interviews will take place in the week starting 11th July 2016.

Funding: the funds for this post are available for 2 years

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Candidates should upload their full CV and the names and addresses of 3 referees.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK09075 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

University Lecturer (2 Posts)

From Jobs at the University of Cambridge. Published on May 04, 2016.

Applications are invited for two research-oriented, tenure-track University Lectureships in Physiology, Development and Neuroscience available from 1 January 2017 or as soon as possible thereafter. Based in central Cambridge, we are searching for two outstanding scientists, with excellent publication records, undertaking fundable work with synergies with our research programme (http://www.pdn.cam.ac.uk/research/). The research field is open for one post but, for the other post, we are looking to recruit a Neuroscientist and are particularly interested in candidates working in systems or circuitry.

The successful applicants will have PhDs in relevant subject areas, will have aptitude and enthusiasm for teaching, and be willing to contribute effectively to our undergraduate programmes in preclinical medicine, preclinical veterinary science, and natural sciences (http://www.pdn.cam.ac.uk/teaching). They will be expected to contribute to the design and delivery of undergraduate and graduate lecture courses and to perform other academic duties including administration, examining and assessment.

We welcome applications from all qualified candidates and we strongly encourage women to apply. Appointment will be based on merit alone.

Informal enquiries may be made to Professor Bill Harris, Head of Department (wah20@cam.ac.uk; +44 (0) 1223 766137/333772).

Appointment will be made at University Lecturer level with a probationary period of five years, with appointment to the retirement age thereafter. The pensionable salary scale starts at £38,896 to £49,230 per annum. Once an offer of employment has been accepted, the successful candidates will be required to undergo a health assessment, with a satisfactory outcome determined by the University.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that, in the Upload section of the online application, you upload your Curriculum Vitae (CV), a research publication list which highlights your three most important published outputs, and a covering letter of no more than two pages, outlining current and future plans, indicating the fit within the research profile of the Department and how you might contribute to our teaching. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

The closing date for applications is midnight on Sunday 10 July 2016.

Please quote reference PM09036 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate: Novel analgesics based on antagonism of TRPV1-AKAP binding (Efficacy Studies) (Fixed Term)

From Jobs at the University of Cambridge. Published on May 03, 2016.

A postdoctoral research associate or research assistant position is available for a joint BBSRC-funded project between Dr Katherine Stott of the Department of Biochemistry, University of Cambridge, and Prof Peter McNaughton, of King's College London. Please note that this position will be located in University of Cambridge space on the GlaxoSmithKline Open Innovation campus, Stevenage. In additional to this position we have two postdoctoral research associate posts which are currently being advertised, vacancy refs: PH09023 - http://www.jobs.cam.ac.uk/job/10246 and PH09024 -http://www.jobs.cam.ac.uk/job/10247.

The aim of the work is to develop novel analgesics that will act by preventing the interaction between the TRPV1 ion channel and a scaffolding protein named AKAP79. Previous work in our labs has identified this binding site as an important analgesic drug target, and the aim of the project is now to enhance our knowledge of the structure of the site, and then to employ this knowledge to develop novel peptides that can be tested in animal models of human pain conditions. Thus the project spans the whole range from structural biology through to drug development.

For this research associate or research assistant position we will study the efficacy of peptides that can interrupt the TRPV1-AKAP79 interaction as novel analgesics. An essential requirement is extensive experience in the use of animal models of human painful conditions, and expertise with models of neuropathic pain and painful diabetic neuropathy would be an advantage. We will fill this post at either the postdoctoral research associate or the research assistant level, depending on the skills and qualifications of the successful applicant.

The post-holder will work mainly with Christina Hanack and Peter McNaughton in the Stevenage Bioscience Catalyst (SBC) building, located in University of Cambridge space on the GlaxoSmithKline Open Innovation campus, Stevenage, but will also work on other aspects of the project (see separate advertisements) and will need to travel on a regular basis to Cambridge (travel will be reimbursed).

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should submit a CV with list of relevant publications, a cover letter explaining why they are suitable for the position and the contact details of at least two referees.

Informal enquiries can be made to either Katherine Stott at ks123@cam.ac.uk or Peter McNaughton at peter.mcnaughton@kcl.ac.uk.

Please quote reference PH09026 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate: Novel analgesics based on antagonism of TRPV1-AKAP binding (Functional Studies) (Fixed Term)

From Jobs at the University of Cambridge. Published on May 03, 2016.

This is one of two postdoctoral research associate positions that are available for a joint BBSRC-funded project between Dr Katherine Stott of the Department of Biochemistry, University of Cambridge, and Prof Peter McNaughton, of King's College London. Please note that this position will be located in University of Cambridge space on the GlaxoSmithKline Open Innovation campus, Stevenage. For further details on the second post-doctoral position please view the separate advertisement on the Cambridge University website, vacancy ref: PH09023 - http://www.jobs.cam.ac.uk/job/10246.

The project is also looking to recruit a postdoctoral research associate or research assistant, vacancy ref: PH09026 - http://www.jobs.cam.ac.uk/job/10249

The aim of the work is to develop novel analgesics that will act by preventing the interaction between the TRPV1 ion channel and a scaffolding protein named AKAP79. Previous work in our labs has identified this binding site as an important analgesic drug target, and the aim of the project is now to enhance our knowledge of the structure of the site, and then to employ this knowledge to develop novel peptides that can be tested in animal models of human pain conditions. Thus the project spans the whole range from structural biology through to drug development.

For this postdoctoral position we aim to purify TRPV1 and AKAP79, or fragments that contain the interacting domains, and will study the ability of peptide antagonists to prevent the interaction. Essential requirements are a detailed knowledge of protein purification and of assays (such as surface plasmon resonance) used to study protein-protein interaction.

Candidates must either hold or be about to be awarded a PhD.

The post-holder will work mainly with Christina Hanack and Peter McNaughton in the Stevenage Bioscience Catalyst (SBC) building, located in University of Cambridge space on the GlaxoSmithKline Open Innovation campus, Stevenage, but will also work on other aspects of the project (see separate advertisements) and will need to travel on a regular basis to Cambridge (travel will be reimbursed).

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should submit a CV with list of relevant publications, a cover letter explaining why they are suitable for the position and the contact details of at least two referees.

Informal enquiries can be made to either Katherine Stott at ks123@cam.ac.uk or Peter McNaughton at peter.mcnaughton@kcl.ac.uk.

Please quote reference PH09024 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate: Novel analgesics based on antagonism of TRPV1-AKAP binding (Structural Biology/NMR) (Fixed Term)

From Jobs at the University of Cambridge. Published on May 03, 2016.

This is one of two postdoctoral research associate positions that are available for a joint BBSRC-funded project between Dr Katherine Stott of the Department of Biochemistry, University of Cambridge, and Prof Peter McNaughton, of King's College London. For further details on the second post-doctoral position please view the separate advertisement, vacancy ref: PH09024 - http://www.jobs.cam.ac.uk/job/10247

The project is also looking to recruit a postdoctoral research associate/research assistant, vacancy ref: PH09026 - http://www.jobs.cam.ac.uk/job/10249

The aim of the work is to develop novel analgesics that will act by preventing the interaction between the TRPV1 ion channel and a scaffolding protein named AKAP79. Previous work in our labs has identified this binding site as an important analgesic drug target, and the aim of the project is now to enhance our knowledge of the structure of the site, and then to employ this knowledge to develop novel peptides that can be tested in animal models of human pain conditions. Thus the project spans the whole range from structural biology through to drug development.

For this postdoctoral position the aim is to use NMR to resolve the molecular structure of the TRPV1-AKAP79 interacting domains. An essential requirement is a detailed knowledge of expression and purification of proteins and the use of NMR in protein structural studies.

Candidates must either hold or be about to be awarded a PhD.

The post-holder will work mainly with Katherine Stott, in the Department of Biochemistry, University of Cambridge in Central Cambridge but will also be involved closely with other aspects of the project (see separate advertisements) and will need to travel on a regular basis to Stevenage Bioscience Catalyst where major parts of the project will be carried out (travel will be reimbursed).

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should submit a CV with list of relevant publications, a cover letter explaining why they are suitable for the position and the contact details of at least two referees.

Informal enquiries can be made to either Katherine Stott at ks123@cam.ac.uk or Peter McNaughton at peter.mcnaughton@kcl.ac.uk.

Please quote reference PH09023 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate: The role of RNA binding proteins in regulating the alternative splicing programme during differentiation of vascular smooth muscle cells from embryonic stem cells. (Fixed Term)

From Jobs at the University of Cambridge. Published on Apr 29, 2016.

A 2-year postdoctoral research associate position is available to work jointly in the groups of Professor Chris Smith in the University of Cambridge, Department of Biochemistry and Dr Sanjay Sinha in the Anne McLaren Laboratory, Cambridge Stem Cell Institute, on the roles of critical RNA binding proteins in controlling alternative pre-mRNA splicing programmes during differentiation of human vascular smooth muscle cells (VSMC) from embryonic stem cells. The project will involve mRNA-Seq profiling of hES to VSMC differentiation, and how this is affected by inducible knockdown or overexpression of regulatory RNA binding proteins.

Candidates will ideally have expertise in: RNA biology (alternative splicing), stem cell biology, smooth muscle cells, analysis of mRNA-seq data-sets.

The successful candidate must have a PhD in a relevant science.

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries can be made to Professor Chris Smith - cwjs1@cam.ac.uk

Please quote reference PH09032 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Post-doctoral Research Associate: Construction of a genome scale functional proteomic map (Fixed Term)

From Jobs at the University of Cambridge. Published on Apr 28, 2016.

This postdoctoral research position is for a collaborative project of the Ralser Lab. (Department of Biochemistry, University of Cambridge and The Francis Crick Institute) and the Lilley Lab. (Cambridge Centre for Proteomics, University of Cambridge), and aims, in collaboration with the mass spectrometry manufacturing industry, to construct the first genome-spanning proteomic map of a eukaryote. This is an exciting, but challenging project, will yield a novel depth of the insight into how the eukaryotic proteome is functioning, and combines the complementary experience of the Ralser and Lilley Labs.

Here, we aim to recruit an experimentalist, however, as we will also seek a computational postdoctoral researcher to join the team, postdocs/PhDs with a relevant background in computational biology/ biological machine learning or data processing are encouraged to apply as well.

The ideal candidate will have recently completed, or is about to complete a PhD in Biology, Biochemistry, or Systems Biology, and has either had contact with yeast or microbial functional genetics or genomics, proteomics, or metabolomics. Ideally, the candidate will have hands-on experience with liquid chromatography, mass spectrometry, or similar analytical hardware. As for all projects of data-driven biology, apart from the listed experimental skills, we welcome applicants with an affinity for computational data processing that exceed beyond using Office software, although we will provide the appropriate training. The candidate must possess a track record that documents his/her productivity in the biosciences, and is willing to join a dynamic team both located in Cambridge and at the Francis Crick Institute.

Fixed-term: The project is intended to be completed in 2020; the post is available for 1 year in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Further information is available from Markus Ralser - mr559@cam.ac.uk

Please quote reference PH09015 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Apr 21, 2016.

University of Cambridge Department of Veterinary Medicine West Cambridge Site

Limit of Tenure: 4 years

Applications are invited for this postdoctoral position, funded by BBSRC through an sLoLa consortium, on a project aiming to advance protein glycan coupling technology (PGCT) for the development of a new generation of veterinary vaccines.

The main focus of the research at Cambridge, led by Dr Andrew Grant and Professor Duncan Maskell, is to carry out detailed molecular biology to construct glycoconjugate assembling bacterial vaccine strains, and to support the evaluation of the immunogenicity and protective efficacy of candidate vaccines in chickens.

Applicants should have a PhD in bacterial infection. Knowledge of, and experience in, the field of bacterial infectious disease research is essential. Expertise in molecular biology is also required and knowledge and experience of immunoassays is highly desirable. The candidate must value teamwork and collaboration, have good administrative and interpersonal skills, and high computer literacy especially in relation to analysis of DNA sequences and the use of bioinformatics software.

For informal enquires please contact: Natalie Wills on nw366@cam.ac.uk

Closing date 6 June 2016

Interviews will be held on 8 July 2016

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please quote reference PP08961 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

RCVS Listed and Qualified Veterinary Nurse

From Jobs at the University of Cambridge. Published on Apr 19, 2016.

UNIVERSITY OF CAMBRIDGE DEPARTMENT OF VETERINARY MEDICINE WEST CAMBRIDGE SITE

Salary - £21,605.00 - £25,023.00

Fixed-term: The funds for this post are available for 1 years in the first instance.

We have an exciting opportunity for a Listed and Qualified Veterinary Nurse to join us from 1st June 2016 or as soon as possible after that date.

The role will be to provide nursing to an excellent standard for the Queen's Veterinary School Hospital, to meet the needs of the service in the Small Animal Wing and Theatre Suites. The role holder will be expected to be flexible and will work in both areas as the need arises.

This role will predominantly be based in the Small Animal Wing.

The role in Small Animal inpatients will include surgical, medical and critical care nursing (training can be given in critical care procedures). Cleaning, hygiene and administration duties linked to inpatient care will form a reasonable percentage of the working day. On call and weekend duties as required on a rota basis.

The role in the Theatre suites will provide pre, intraoperative and post-operative care of surgical patients, medical diagnostics and administration duties linked to each case, various cleaning and hygiene duties and to undertake on call and weekend duties on a rota basis to meet the demands of the business.

This is a varied role where no two days are the same, so we are seeking someone with a passion for nursing, with the ability to communicate with all levels of staff, students and clients. The ability to work within a team and work well under pressure are essential.

If you have any questions about this role please contact Julie Ingham on ji217@cam.ac.uk

Closing date: 5th June 2016

Interviews will be held : 27th June 2016

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

To submit an application for this vacancy, please click on the link 'Apply online' This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) before completing the online application form or visit the following website: http://www.jobs.cam.ac.uk/
Further particulars for the role and information about the Department are available here: www.vet.cam.ac.uk The website for The Queens Veterinary School Hospital is available here: http://qvsh.co.uk/

Please quote reference PP08514 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Group Leader

From Jobs at the University of Cambridge. Published on Mar 10, 2016.

Applications are invited for a Research Group Leader position in the Sainsbury Laboratory.

The Sainsbury Laboratory is a Research Institute dedicated to plant developmental biology located in central Cambridge, UK. It has excellent resources and core facilities, with state-of-the-art equipment including growth rooms, glasshouses, microscopy and computing facilities. There is a collaborative research ethos where diversity is welcomed, and Group Leaders can take risks in a supportive and collegial environment. We are seeking to appoint one Group Leader who can both contribute to and benefit from this environment. In particular we are looking for a scientist with imaginative research ideas that will contribute to our understanding of plant development, by elucidating the links between genotype and phenotype in any appropriate study system.

Applicants will typically have experience of relevance to the overall scientific focus of the Laboratory, in particular plant development and/or computational modelling of development. Applicants should have exceptional promise for, or a proven record of research achievement in the field, and provide strong evidence of their potential to make significant contributions to basic plant science research.

The position is open to applicants of any nationality and can be awarded across a broad range of seniority. Applicants who currently hold a permanent post in a University or other Research Organisation are welcome to apply. The successful applicant will initially receive support for five years, including salary and benefits. The annual pensionable salary of a Group Leader is dependent on experience and may range from grade 9 (£38,896-£49,230), grade 10 (£52,219-£55,389), grade 11 (£57,047-£66,108) or grade 12 (£68,085-£102,906), supplemented by a 30% Gatsby distinction award. Ample laboratory space, administrative support, and unrestricted research funds in the range of £250,000 per annum will be available. Group Leaders are also eligible to apply for competitive research grant support from other sources. Pending a rigorous peer-review process, appointment is renewable in 5 years installments. There is no overall limit to the number of potential renewals.

Applications can be submitted electronically at any time as pdf files and should include a full CV, a research proposal for the initial five year period as Group Leader and the names of at least three referees. Completed applications should be sent by e-mail to: enquiries@slcu.cam.ac.uk

Further details about the post and the Sainsbury Laboratory are available on the Sainsbury Laboratory web site: http://www.slcu.cam.ac.uk/

Fixed-term: The funds for this post are available for 5 years in the first instance.

Please quote reference PT08605 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.