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Research Associate x 2 in Structural Biology: Structural basis of meiotic chromosome organization by the synaptonemal complex (Fixed-term)

From Jobs at the University of Cambridge. Published on Aug 28, 2015.

Research Associates in Structural Biology: Structural basis of meiotic chromosome organisation by the synaptonemal complex and associated proteins.

Two postdoctoral positions are available in the group of Dr. Luca Pellegrini in the Department of Biochemistry of the University of Cambridge in Central Cambridge, to work on the essential role of the synaptonemal complex in establishing the functional architecture of parental chromosomes in meiosis, which is essential for correct pairing and recombination (Davies et al, Open Biology, 2012; Syrjanen et al, eLife, 2014). A multi-disciplinary approach involving biochemical, biophysical and cellular experiments will be used to elucidate the molecular mechanisms of synaptonemal complex assembly on the meiotic chromosome axis. The ultimate goal of the project is to advance our understanding of meiotic chromosome organisation, by means of biochemical reconstitution and structural characterisation using purified protein components.

Candidates will hold or about to be awarded a PhD in Biochemistry, Biophysics, Molecular Biology or the equivalent and must have a proven track record of research achievements. Previous experience in the analysis of multi-protein complexes and protein-DNA interactions, as well as familiarity with biophysical techniques such as X-ray crystallography, electron microscopy and single-particle analysis would be an advantage. One of the positions would be suitable for candidates trained in cellular biology and with an interest in the study of molecular mechanisms.

The positions are available from November 1st, 2015.

Fixed-term: The funds for this post are available for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries can be made to Luca Pellegrini at lp212@cam.ac.uk.

Applicants should submit a CV with list of relevant publications, a cover letter explaining why they are suitable for the position and the contact details of at least two referees.

Please quote reference PH06670 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Service Technician

From Jobs at the University of Cambridge. Published on Aug 26, 2015.

Applications are invited for a service technician to work in our biomedical facility in central Cambridge. We are a modern, busy research institute seeking someone who after initial training will be able to operate simple machinery, including dismantling and reassembling equipment for washing and sterilising animal cages. The applicant will also be involved in the collection and delivery of goods, maintaining stocks and assisting biomedical technicians with the general maintenance of the facility and disposal of waste. Previous experience of working in an animal facility or research environment would be desirable but is not essential as full training will be provided.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

If you have any questions about this vacancy or the application process, please contact the NACWO at jobs@gurdon.cam.ac.uk. Please quote reference PR06339 on your application and in any correspondence about this vacancy. Previous applicants need not apply.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Post-Doctoral Research Associate: Cell Biology of Planar Polarity

From Jobs at the University of Cambridge. Published on Aug 26, 2015.

Applications are invited for a post-doc position to work in José Casal and Peter A Lawrence's group to study the cell biology of planar cell polarity. Drosophila is used as a model organism.

This position is suitable for an independent-minded postdoc with knowledge and skills in live imaging, cell biology, and genetics

Required experience / knowledge for the position

Essential:

A PhD in cell biology, genetics or closely related subjects (completed or completion imminent).

Knowledge and interest in the broad field of our research.

Ability to organise time, plan ahead and to work effectively independently.

Good data handling and data analysis skills.

Good communication skills (written and oral).

Ability to work in a team and relate well with others.

An inventive mind willing and able to devise new techniques, improve existing ones and create original projects.

Proven ability to prepare scientific manuscripts of quality.

Prerequisites will include some or all of the following:

An understanding of the recent developments in fly genetic research.

Experience of live imaging,confocal microscopy and tracking multiply tagged proteins.

Experience of laser ablation techniques.

Duties and responsibilities:

Develop research objectives, projects and proposals.

Conduct individual and collaborative research projects.

Write and contribute to publications or disseminate research findings using other appropriate media.

Assess, interpret and evaluate outcomes of research .

Make presentations at conferences or exhibit work in other appropriate events.

Routinely communicate complex and conceptual ideas to those with limited knowledge and understanding as well as to peers.

Supervise postgraduate research students and undergraduates on short stays with us.

Mentor and coach colleagues with less experience and advise on personal development.

Supervise other researchers.

Fixed-term: The funds for this post are available for up to 36 months.

Fixed-term: The funds for this post are available for up to 36 months.

Previous applicants need not apply

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PF06530 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Post-doctoral Research Associate in Developmental Biology and Microscopy

From Jobs at the University of Cambridge. Published on Aug 26, 2015.

The Zernicka-Goetz lab (http://www.pdn.cam.ac.uk/zernickagoetzlab/) studies development of cell lineages and patterning and the interactions between stem cells in the early mammalian embryo.

We are looking for talented and creative post-doctoral research associate(s) to investigate mechanisms of morphogenesis in the mouse embryo from pre-implantation stages to gastrulation. The lab applies high-resolution time-lapse imaging and quantitative analysis of embryo development, in concert with a variety of techniques for uncovering and modulating gene expression.

Recently the lab developed a unique method for culturing embryos that recapitulates the main events occurring during implantation (Bedzhov and Zernicka-Goetz, Cell 2014). This method is highly suited for studying morphogenesis and the interactions between distinct stem cell populations as the embryo is built.

The lab is equipped with state-of-the-art microscopes for live imaging of morphogenesis: spinning-disk and scanning confocals and a two-photon microscope with a wide-range tuneable IR laser for deep, long-term imaging of embryos from early to later stages.

The successful candidate(s) should have a PhD in biology or biophysics and will work on their own project but should be willing to undertake collaborative studies with other members of the group. They will have one or more of the following skills: Developmental biology, ideally on the mouse embryo but experience of other model organisms also welcome; Molecular cell biology, basic molecular biology and familiarity with principles of cell biology; Microscopy, knowledge of optics, advanced microscopy and data collection for continued development of non-invasive live imaging techniques; Data analysis and model building, image analysis with some knowledge of analysis-driven programing being helpful but not essential.

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Could all applicants, please also email a covering letter and a CV with the names of two referees directly to Prof. Magdalena Zernicka-Goetz (mz205@cam.ac.uk).

Please quote reference PM06966 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Client Services Administrator (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 24, 2015.

The Queen's Veterinary School Hospital is looking for a pro-active, flexible team player to work in the Reception area of both the Small and Large Animal sections as part of the Hospital Administration Team. This is a full time position working Monday to Thursday 8.45am to 5.15pm and 8.45am to 4.15pm on a Friday, with one hour for lunch each day, some flexibility is required. You will be expected to work in the large animal and small animal reception areas.

You will be the first point of contact for our clients, therefore a friendly manner, combined with excellent communication skills are essential. You will be responsible for receiving incoming calls and faxes, billing clients and taking payments, booking appointments, liaising with clients, referral practices, clinicians, nurses and students and therefore knowledge of medical terminology would be advantageous.

The ability to plan and prioritise your own workload is essential along with being able to work within a team environment.

You should have a sound knowledge of IT systems and should be numerate, accurate and have an eye for detail. You will be educated to 'A' level standard or have experience in a similar working environment.

For informal enquiries please contact Kate Smith email: kw306@cam.ac.uk

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Closing Date: 6 September 2015

Interviews will be held: 21 September 2015

Please quote reference PP06954 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate in Synthetic Biology (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 21, 2015.

This exciting vacancy is under the supervision of Dr Jim Haseloff to research imaging and quantification of engineered biofilms. You will be based in the synthetic biology lab in Plant Sciences, Central Cambridge.

We have developed computational method for the simulation of biofilm-scale bacterial populations, and implemented this in the CellModeller software package (ref 1-3). The software allows modelling of (i) genetically mediated information flow, and (ii) the 3D physical interactions between cells that are required for multiscale modeling of large microbial populations. The emergent properties exhibited by a multitude of growing, signaling, and responding bacterial cells are central to the rational design of synthetic biofilms.

We are using the CellModeller software to experiment with the creation of plasmid based logic, using conditional interactions between donor cells, mobilised plasmids, and recipients to create different patterns of information transfer across a mixed biofilm. The in silico models can contain cells with different genetic programmes and/or states, and these mixed cells can be arranged in different patterns in order to create different initial conditions and emergent patterns, or "wiring".

Simple biofilm patterning techniques and selective inoculation of engineered host strains will be used to parameterise and validate observations that arise from in silico modelling work. Non-invasive plate imaging and high resolution confocal microscopy will be used to resolve features to single cell resolution, and to track independently host genotypes and mobile plasmids. This will provide important empirical tests for the modelling approach.

A position is available immediately for the appointment of a synthetic biologist to help with this work. Research experience with (i) routine handling of microbes, such as E. coli and yeast, (ii) DNA manipulation and assembly techniques and (iii) quantitative biological analysis is necessary. Experience with the development of software or hardware for instrumentation would be an advantage. Candidates should have obtained or be close to obtaining a PhD in a Biological Sciences subject or a closely related field.

1) Rudge TJ, Steiner PJ, Phillips A and Haseloff J. Computational modeling of synthetic microbial biofilms. ACS Synthetic Biology, 1:345-352, (2012).

2) Rudge TJ, Steiner PJ, Kan A and Haseloff J. Cell shape-driven instability generates self-organised fractal patterning of cell layers. ACS Synthetic Biology 2:705-714, (2013).

3) http://www.cellmodeller.org

More information about the position can be obtained from Dr Jim Haseloff (jh295@cam.ac.uk) and background information can be found at the laboratory web site at http://www.haseloff-lab.org.

Fixed-term: The funds for this post are available until 30 September 2016 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application.

Please quote reference PD06942 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 20, 2015.

A postdoc position in biological big data analytics is available in the laboratory of Dr. Rafael E. Carazo Salas. The ideal candidate will be a highly motivated researcher with expertise in Machine Learning, image analysis, and/or large-scale data management, visualization and mining.

The position is part of an exciting interdisciplinary collaboration between the OME consortium, EMBL/EBI and the University of Cambridge, to help further our recently developed web-based, visual-analytics tool Mineotaur (Antal et al, in revision; http://vizbi.org/Posters/2014/E02/; http://www.mineotaur.org/), which allows non-computational scientists to access and mine the biological Big Data from high-throughput/high-content microscopy cellular phenotyping projects, and integrate it in the BBSRC-funded Big Data Image Data Repository project. Further information can be found at http://www.gen.cam.ac.uk/research-groups/carazo-salas

You should have a PhD in a relevant area , e.g. image analysis, computer vision, bioinformatics, Machine Learning or big data applications. You should be able to prove your enthusiam for the project, have a record of excellence and a desire to work in an interdisciplinary environment.

Fixed-term: The funds for this post are available until 30 June 2016 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries should be addressed to Dr. Rafael E. Carazo Salas cre20@cam.ac.uk

Please quote reference PC06934 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Pluripotent Stem Cell Platform Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 20, 2015.

Fixed-term: The funds for this post are available until 31 January 2018 in the first instance.

The Pluripotent Stem Cell Platform (PSCP) is a hub in the UK Regenerative Medicine Platform, a joint research council programme to tackle the critical challenges in developing new regenerative treatments (www.ukrmp.org.uk). PSCP is a multi-disciplinary collaboration focussed on the quality controlled manufacturing and differentiation of human pluripotent stem cells suitable for clinical applications (http://www.ukrmp.org.uk/hubs/cell-behaviour-differentiation-and-manufacturing/).

A post-doctoral position is available for a PSCP project based in Cambridge under the direction of Roger Barker, Ludovic Vallier and Austin Smith at the Wellcome Trust-MRC Stem Cell Institute (www.stemcells.cam.ac.uk).

The research is centred on optimising the generation from human embryonic and induced pluripotent stem cells of neural derivatives suitable for development of cell based therapies, in particular midbrain dopaminergic neurons for Parkinson's disease.

Candidates should have a PhD with experience in the culture and analysis of pluripotent stem cells or neural stem cells and/or neuronal differentiation and functional characterisation supported by relevant publications. Applications are encouraged from candidates with a translational focus and an appreciation of cell production requirements for clinical trials.

Technical support is available and access to a range of flow cytometry, imaging and qPCR instrumentation.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Sunday 20 September 2015.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Informal enquiries about the post are also welcome via email on jobs@stemcells.cam.ac.uk.

Interviews will be held week commencing 12 October 2015. If you have not been invited for interview by 9 October 2015, you have not been successful on this occasion.

Please quote reference PS06912 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 19, 2015.

A position is available for a postdoctoral Research Associate based in the Evolution and Diversity Group in the Cambridge University Botanic Gardens, and in the Department of Plant Sciences, under the supervision of Dr Samuel Brockington.

Candidates must have, or be close to finishing, a PhD in a relevant biological discipline and will have a strong background in all or some of the following fields: bioinformatics, phylogenomics, phylogenetics, transcriptomics, evolutionary biology, and plant systematics. The candidate will have a strong publication record, including first author publications in quality peer-reviewed journals. The following skills are essential: excellent programming skills in the candidate's preferred language(s), a strong background in statistics and data visualization, and experience in the analysis of transcriptome data. Prior intellectual interest or evidence of previous research in the areas of phylostratigraphy, taxonomic-specific gene radiations, and genome or gene duplications is highly desirable. Hands-on experience of relevant wet-lab techniques would be an advantage.

The appointee will initially work within an on-going NSF-funded large-scale transcriptomics project, examining the genomic basis of extreme adaptation in the flowering plant order Caryophyllales. The Caryophyllales contain ~6% of all flowering plant species and exhibit extreme life history diversity, including tropical trees, temperate herbs, long-lived succulent cacti, and a diverse array of carnivorous plants. This project will leverage recent advances in gene sequencing technologies and computational methods to evaluate the extent to which changes in life history and ecophysiology in plants are correlated with changes in evolutionary rate and gene diversification. Transcriptomes will be sequenced for over 300 representative species of Caryophyllales, and analyses of evolutionary rate shifts in both traits and the transcriptome will be used to assess how life history and ecophysiology have influenced genomic evolution, and vice versa. These analyses will yield unprecedented insight into the evolution of several genetic pathways of fundamental importance in flowering and crop plants, including those associated with flower development, photosynthesis, and pigmentation.

The appointee will develop a bioinformatics-driven programme of research and will be enabled to lead both analyses and tool development, and to first-author publications. The appointee will be encouraged to develop novel tools and bioinformatic pipelines to suit specific questions. Open source code is encouraged.

Fixed-term: The funds for this post are available for 36 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For further information, please contact Dr Samuel Brockington (sb771@cam.ac.uk)

Please quote reference PD06870 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate - Structural Biology of Membrane Proteins (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 18, 2015.

A postdoctoral Research Associate position is available to work on the structural biology of mammalian membrane proteins using the latest technology in X-ray crystallography. The post is based in the laboratory of Dr Simone Weyand, University of Cambridge, Departmental of Biochemistry, Central Cambridge and is for 1 year initially.

The role involves the ideal candidate to carry out all the steps from cloning to structure determination of a human GPCR. The successful candidate will be highly motivated with a track record of working on integral membrane proteins and expertise in at least one, and preferably more, of the following areas: over-expression in insect or mammalian cells, membrane protein purification, and X-ray crystallography structure determination. Candidates must be self-motivated individuals who enjoy working as part of a collaborative and multidisciplinary team. Strong leadership, communication and teamwork skills are decided assets.

Candidates should hold a PhD or the equivalent in a relevant specialist subject or have recently submitted for a PhD.

Fixed-term: The funds for this post are available for 1 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made to Dr Simone Weyand- sw644@cam.ac.uk

Please quote reference PH06900 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 18, 2015.

Applications are invited for a Post-doctoral Research Associate position in the group of Dr Philip Wigge at The Sainsbury Laboratory, Cambridge University, to work on a project focussed on understanding the regulatory logic underpinning transcriptional responses of plants to warmer temperature. The role holder will concentrate on the bioinformatic analysis of large-scale datasets within the lab and liaise with other group members in the design of further experiments to test and validate hypotheses for how plants sense and respond to temperature. This post requires candidates of exceptional ability who have an extensive formal educational record in the fields of both biology and computational science. The ultimate goal of the research is to make crop plants resilient to field stress conditions and thus contribute to the economic competitiveness of the UK.

Applicants must hold undergraduate degrees in both computer science as well as biology. Applicants must also have a PhD or equivalent experience, in a relevant field involving the use of mathematics and or computational biology, to understand genetic mechanisms. An in depth understanding of computational biology, genetics and transcriptional regulation in eukaryotic cells is essential, alongside programming skills in Java and R and experience with machine learning and biophysical simulation. Previous experience in gene regulation, TF binding site organisation and gene expression noise would also be desirable.

The role holder must be able to communicate clearly and present data to other members of the group, external collaborators and sponsor agencies (grant application). Candidates will also need to work well in a team.

The Laboratory provides a welcoming and collaborative environment with a wide-range of family-friendly benefits and development opportunities. More about the Sainsbury Laboratory, further information for the role and details of what the University offers to employees, can be found at: http://www.slcu.cam.ac.uk/.

The post is available immediately.

Fixed-term: The funds for this post are available for 2.5 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload a copy of your full CV, a supporting statement and contact information of three referees.

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within two weeks of the closing date, please consider your application as unsuccessful on this occasion.

Please quote reference PT06901 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Postdoctoral Research Associate (CRISPR screens in human stem cell models of Alzheimer's disease)

From Jobs at the University of Cambridge. Published on Aug 17, 2015.

Applications are invited for a postdoctoral research associate position in the Livesey lab to use whole genome CRISPR screens to identify novel modifiers of Alzheimer's disease progression, using human stem cell models of dementia (see papers from the lab published in Cell Reports, Nature Neuroscience and Science Translational Medicine). The successful candidate will be a member of the Alzheimer's Research UK Stem Cell Research Centre within the Gurdon Institute, funded by the Alborada Trust. The overall aim of the Centre is to use stem cell models to identify new pathways for potential therapeutics for Alzheimer's disease. To do so, we are focused on using stem cell models of Alzheimer's disease to understand key mechanisms underpinning how the disease starts and spreads through the brain in both the inherited and the common, sporadic form of Alzheimer's disease.

Applicants should have, or expect to obtain shortly, a PhD in the life or physical sciences. Experience in genetics, stem cell biology, pharmacology, molecular biology, biochemistry or neurodegeneration would be an advantage, but we are primarily looking for enthusiastic PhD-level scientists who like solving problems.

Limited funding: The funds for this post are available until 30 April 2017 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applications should include a CV, brief statement outlining key areas of expertise and reasons why you would like to join the group. Informal enquiries about the vacancy should be directed to Rick Livesey (rick@gurdon.cam.ac.uk). Interviews will be held in late September.

Please quote reference PR06890 on your application and in any correspondence about this vacancy. The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Research Associate in Bioinformatics for Mass Spectrometry (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 14, 2015.

Postdoctoral positions in lipidomics and metabolomics

A postdoctoral research associate position is available for up to three years (12 months in the first instance) to work in the laboratory of Dr J.L. Griffin, University of Cambridge, Department of Biochemistry, Tennis Court Road, Cambridge. The project will develop tools to measure lipid species in conjunction with ion mobility, an exciting development in mass spectrometry which will allow the separation of ions according to their cross sectional area as well as their mass to charge ratio. It is envisaged that the successful candidate will work alongside an experienced mass spectrometrist involved in method development, whilst developing new software tools for processing the data obtained.

We are looking for an bioinformatician with experience in processing biological mass spectrometry data or other relevant experience such as experience in signal processing. The work is a collaborative project between Dr. J.L Griffin (Dept of Biochemistry), Prof. Michael Wakelam (Babraham Institute) and Agilent technology. As part of this project the research associate will have access to a state of the art ion mobility Q-ToF LC-MS to develop new tools for lipidomics, and building on our work in diabetes and metabolic diseases (Griffin) and cancer (Wakelam) use the instrument to explore cellular signalling in these disease processes. Some examples of this work can be found in Roberts LD et al., Lancet Endocrinology, 2014; Roberts LD et al., Methods in Enzymology, 2014; Zhang Q & Wakelam MJ, Adv Biol Regul 2014.

Skills required are bioinformatics for metabolomics or proteomics and a general interest in metabolism and disease processes in mammals. Previous work in metabolomics and/or lipidomics would be an advantage but we will consider relevant experience in other areas such as aspects of signal processing

Applicants should have a PhD or are about to submit or have the equivalent in a relevant science.

Fixed-term: The funds for this post are available for 12 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made to Dr J.L Griffin - jules.griffin@mrc-hnr.cam.ac.uk

Please quote reference PH06024 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant

From Jobs at the University of Cambridge. Published on Aug 13, 2015.

A full-time Research Assistant position is available in the lab of Dr Rick Livesey at the University of Cambridge, Gurdon Institute. The lab uses human induced pluripotent stem cells to study human brain development and disease, with a major focus on Alzheimer's disease.

We are now seeking to hire a research assistant to join our dynamic team in the Alzheimer's Research UK Stem Cell Research Centre to assist in the production and maintenance of human stem cell lines. Core duties will involve reprogramming primary cells to generate pluripotent stem cells, managing stocks and samples, and being responsible for ongoing quality control procedures.

Preferred skills and experience:

  • Degree or equivalent in life or physical sciences
  • Previous research laboratory experience
  • High attention to detail and good record keeping is essential
  • Good communication and organisational skills
  • Familiarity with human stem cell culture would be an advantage
  • Ability to work unsupervised and as part of a team
  • Previous experience in molecular biology techniques; cloning, PCR, RNA analysis
  • Reliability and enthusiasm.
  • Some flexibility in working hours will be required to keep cells over weekends.

Limited funding: The funds for this post are available until 30 April 2017 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applications should include a CV, brief statement outlining key areas of expertise and reasons why you would like to join the group. If you have any queries about the vacancy, please email j.fisher@gurdon.cam.ac.uk. Interviews will be held in late September.

Please quote reference PR06869 on your application and in any correspondence about this vacancy. The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Graduate Student Administrator (Part Time)

From Jobs at the University of Cambridge. Published on Aug 13, 2015.

The Department of Plant Sciences is seeking to recruit a part-time Graduate Student Administrator (25 hours per week)

The successful candidate will be responsible for all aspects of graduate student administration, including initial enquiries and online applications via CAMSIS (Cambridge Student Information System), interview arrangements, dealing with studentship funding applications, and collating monitoring reports. The role-holder works closely with the Chair of the Department's Graduate Education Committee, the Board of Graduate Studies, and academic supervisors. As Secretary to the Graduate Education Committee, they will compile agendas and take minutes.

Applicants should possess excellent organisational and communication skills, combined with an ability to work with accuracy and attention to detail at all times. Familiarity with standard software packages is essential, preferably including online application systems.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries about this post can be sent to Catherine Butler, Department Administrator (cek31@cam.ac.uk)

Please quote reference PD06837 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate: Single-molecule and Super-resolution Imaging of White matter (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 13, 2015.

Fixed-term: The funds for this post are available for 3 years in the first instance.

We are looking for three motivated, ambitious and independent post-doctoral researchers to join an interdisciplinary research project on Alzheimer's disease, developing novel models of human white matter, single-molecule fluorescence techniques, sensitive biosensors and cutting-edge optical imaging methods. The project is ambitious, aiming to make step changes in human stem cell development, tissue culture engineering, biosensor generation and understanding of Alzheimer's disease. This focused collaborative project brings together the expertise of Dr. Káradóttir (Wellcome Trust - MRC Stem Cell Institute), Dr. Lee (Dept. of Chemistry), Prof. Spillantini (Dept. of Clinical Neuroscience), Dr. Coleman (John van Geest Centre for Brain Repair), Prof. Brayne (Institute of Public Health), Prof. Brown (Dept. of Biochemistry), and Prof. Hall (Dept. Chemical Engineering and Biotechnology), all based at the University of Cambridge.

This multi-departmental arrangement provides an excellent environment for research and career development, as the post holders will benefit from the resources and expertise of biological, physical and medical sciences in this multidisciplinary project.

Homepages of the team:

http://www.stemcells.cam.ac.uk/researchers/principal-investigators/dr-ragnhildur-thra-kradttir

http://www.ch.cam.ac.uk/person/sl591

http://www.ceb.cam.ac.uk/directory/lisa-hall

http://www.brc.cam.ac.uk/principal-investigators/maria-spillantini/

http://www.neuroscience.cam.ac.uk/directory/profile.php?mcoleman

http://www.iph.cam.ac.uk/about-us/key-people/carol-brayne/

http://www.bioc.cam.ac.uk/people/uto/brown

Requirements:

We are looking for candidates that hold (or expect to obtain) a PhD in biophysics, physical chemistry, photonics, optics or related disciplines. Experience with single-molecule fluorescence techniques, generation of biosensors or electrochemical engineering would be highly advantageous. Candidates should have a keen interest in applying physical methods to complex biological systems, although no prior knowledge of neurodegenerative disease or biology is required, and enjoy working in a highly multidisciplinary environment.

The successful candidates will have a strong publication record and enjoy ambitious projects at the frontiers of neuroscience and biotechnology. We are specially looking for candidates that are be self-motivated, collaborative with effective communication skills and enjoy working in a team. Proven capacity to design, execute, and interpret experimental data is essential.

Start date is flexible but can be as early as October 2015.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For informal enquired please contact Dr. Steven F. Lee (sl591@cam.ac.uk).

The closing date for all applications is Monday 31 August 2015.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Interviews will be held in mid September 2015. If you have not been invited for interview by 15th of September 2015, you have not been successful on this occasion.

Please quote reference PS06857 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

BBSRC CASE 4-year PhD Studentship (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 12, 2015.

The Department of Biochemistry is offering a BBSRC CASE 4-year PhD studentship starting in January 2016

The aim of the studentship is to determine the molecular basis of interactions between African trypanosomes and their mammalian hosts, supervised by Professor Mark Carrington in the Department of Biochemistry and Dr Andrea Gonzalez-Munoz at Medimmune. The successful applicant will spend time working at both the Medimmune Research Labs (www.medimmune.com) close to Cambridge and in the Carrington lab (www.mctryps.org/mclab/Home.html) in the Department of Biochemistry (www.bioc.cam.ac.uk).

The studentship is open to UK and other EU nationals and other who qualify for fees at the 'Home' rate, see www.graduate.study.cam.ac.uk/finance/fees/what-my-fee-status

The deadline for applications is Friday 18 September 2015. Applications received after this time will not be considered.

Fixed-term: The funds for this post are available for 4 years in the first instance.

For details of the project and to apply please send a CV, the names and contact details of two academic referees along with a covering letter to Professor Mark Carrington - mc115@cam.ac.uk

Please quote reference PH06864 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Laboratory Technician (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 11, 2015.

Dr Elizabeth Murchison's Wellcome Trust-funded research group at the University of Cambridge, Department of Veterinary Medicine, is seeking a highly motivated and enthusiastic person to fill a new role as Research Laboratory Technician. Dr Murchison's group is a newly established small, interactive and international research team focused on the genetics and evolution of transmissible cancers in dogs and Tasmanian devils. Although this is a full time position, we welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements. Please indicate your preferred working hours on the application form. For further information about Dr Elizabeth Murchison's laboratory, the Transmissible Cancer Group, please see our website: http://www.tcg.vet.cam.ac.uk

Key responsibilities of the role will include:

-Maintaining and curating large sample collections of dog and Tasmanian devil tumours and managing sample quality control pipelines

-Interacting with international collaborators and government agencies to oversee logistics and regulatory documentation associated with biological sample collection and shipment

-Overseeing day-to-day running of the laboratory, including ordering, managing laboratory databases, equipment purchase and maintenance and overseeing laboratory safety procedures

-Overseeing laboratory grant expenditure

-Assisting with research investigating genetics of transmissible cancers in dogs and Tasmanian devils, and assisting other laboratory members with research projects

Essential attributes:

-Bachelors degree in biological science, biomedical science or related discipline

-Previous laboratory research experience in molecular biology and a desire to learn new skills

-High level of computer literacy and an interest in learning new software packages

-Excellent communication and team working skills

-Excellent skills in research planning, record keeping and organisation

Desirable attributes

-Experience in high-throughput sample tracking and laboratory administration

-Experience in grant administration

-Experience in DNA and RNA analysis

-MSc / PhD or equivalent years of laboratory experience

For informal enquires please contact: Dr Elizabeth Murchison epm27@cam.ac.uk

Further particulars for the role and information about the Department can be found at www.vet.cam.ac.uk

Fixed-term: The funds for this post are available for 2 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Closing date: 16 September 2015

Interview date: 7 October 2015

Please quote reference PP06846 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant (Part Time, Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 10, 2015.

Applications are invited for a part time Research Assistant position funded by British Heart Foundation to start as soon as possible. The post is 50% of full-time and the primary duties of the post holder will include western blotting, immunoassays, DNA/RNA extraction, PCR analysis and tissue sample collection.

Applicants must have basic laboratory skills (PCR, sample preparation, blotting) and proficiency with Microsoft Office products, especially Excel. You will possess practical experience in molecular biology. You will also be expected to have a proactive and detail-oriented work ethic, good communication and team working skills, and the ability to work independently when required. Excellent organisational skills and record keeping are essential. Applicants should have a BSc or equivalent degree in a biological science or related discipline.

Fixed-term: The funds for this post are available until 31 August 2017 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please upload your CV and a covering letter outlining your suitability for the post.

Please quote reference PM06838 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Co-ordinator of Cambridge Global Food Security Strategic Initiative

From Jobs at the University of Cambridge. Published on Aug 07, 2015.

We are seeking a co-ordinator to provide high-level support to the Cambridge Global Food Security Initiative (CGFS). CGFS is a Cambridge University Stragetic Initiative, funded by the University's Research Policy committee. The Initiative remit is to ensure affordable access for all to sufficient, safe and nutritious food for an active and healthy life, and to maintain sufficient natural capital to do so sustainably.

The purpose of the co-ordinator role is to organise, manage and deliver activities for the Initiative. Working with the Chair, Co-Chair, Steering Group and others, the post-holder will assist in developing a strategy and vision for CGFS, and in planning and delivering implementation of this strategy. A crucial aspect of the role is managing relationships with stakeholders, combined with communicating and promoting Initiative activities. The post-holder will identify and establish new research collaborators, and will co-ordinate fundraising from a range of sources.

The successful candidate will have a good first degree. A PhD in a relevant field is desirable. She/He will have knowledge of Global Food Security research, policy and practice. They will be able to foster relationships and partnerships with companies, funding agencies and policy makers, and to interact with senior scientists and senior figures in industry, research councils and other sponsors. They will have experience working within a higher education, industry or government environment. Excellent written and IT skills are essential, together with familiarity with development of web-based resources.

Limited funding: The funds for this post are available until 30 September 2017 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application.

Please quote reference PD06830 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Technician - Programmer (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 07, 2015.

Applications are invited for a Research Technician / Programmer based at the University of Cambridge under the supervision of Dr Paul Bays. The successful candidate will work on a Wellcome Trust funded research project investigating how internal noise influences human perception and action.

The appointee will develop and support software platforms for experimenting in a technically-advanced lab, including interfacing with motion tracking technology and web-based crowdsourcing methods (e.g. Amazon Mechanical Turk). He/she will also be responsible for sourcing, developing and maintaining the laboratory's equipment and computer facilities. The post would suit someone with a computing background interested in behavioural science, or someone with a scientific background and a keen interest in programming. There will be opportunity to expand the role to include collection and analysis of research data.

Applicants should have a good honours degree (2.1 or above) in an appropriate discipline. Programming expertise in C/C++ is essential, experience with Matlab and/or Javascript is desirable. Experience of programming in a research environment would be an advantage. Applicants will need to demonstrate the ability to work creatively and independently.

The post is available from 1 October 2015 for a period of 12 months in the first instance.

Further information may be downloaded below.

If you have any questions about this vacancy or the application process please contact Dr Paul Bays (pmb20@cam.ac.uk). More information is available at http://www.bayslab.com/.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Please quote reference PJ06816 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Teaching Administrator

From Jobs at the University of Cambridge. Published on Aug 06, 2015.

We are seeking a capable and enthusiastic person to join the Department in this role which provides the underpinning administration for our undergraduate programmes.

The main responsibilities include working closely with the Director of Undergraduate Education and Course Organisers to support their roles, involving liaison with undergraduate students (approx 240 registered at any one time) as well as contacts internal and external to the University regarding all matters related to undergraduate teaching from organising open days, registering new students, timetabling, providing various documents such as course guides, to graduation. The post holder is a key source of advice relating to the policies and procedures with respect to undergraduate issues in the Department. The post holder will also work closely with a Teaching Secretary and the Secretary to the Department.

You will be able to work both independently and in liaison with others. You will be well-organised and approachable and should possess an excellent standard of written English with an ability to communicate effectively and unambigiously with a wide range of people. Education to at least A level standard is a requirement as are good IT skills including word-processing, email and use of the Internet. You will have experience of preparing agendas and taking minutes. You should have relevant work experience in an office environment; experience in an academic or educational setting and management experience is highly desirable.

Further information may be downloaded below.

Informal questions regarding this post may be sent to Ms Kate Stacey (ks298@cam.ac.uk)

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Please quote reference PJ06797 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Microinjection Technician (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 05, 2015.

Applications are invited for a Drosophila Microinjection Technician position in the Fly Facility at the University of Cambridge Department of Genetics (www.flyfacility.gen.cam.ac.uk). The facility provides services and support to the Drosophila research community, and is probably the largest of its kind in Europe. The Microinjection Technician will play an important role in expanding the services offered by the facility, at a time when Drosophila genetics is undergoing exciting new developments.

The post-holder will work closely with other Fly Facility staff to provide a high quality Drosophila microinjection service. They will inject insect embryos and undertake genetic screening and balancing work as requested by facility users. The post-holder will also contribute to other Drosophila project work ongoing in the facility.

The successful candidate will have a degree in biological sciences and familiarity with working in a research environment. Ideally, they will have a good working knowledge of Drosophila genetics and some practical experience of microinjection. However, since appropriate training will be provided, we will consider candidates with a strong Drosophila background and no microinjection experience. We will also consider candidates with a strong background in microinjection, but little Drosophila experience.

Fixed-term: The funds for this post are available for 12 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries should be addressed to Simon Collier, email psc38@cam.ac.uk

Please quote reference PC06814 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Chief Building Services Technician (Part Time, Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 05, 2015.

Fixed-term: The funds for this post are available until 31 December 2017 in the first instance.

The Cambridge Stem Cell Institute is a world-leading centre of excellence in stem cell biology and regenerative medicine, supported by the Wellcome Trust and the Medical Research Council (www.stemcells.cam.ac.uk). The Institute comprises over 300 researchers spanning fundamental science through to clinical applications. Our vision is of a deep understanding of stem cell biology for the prevention and treatment of human disease.

We are seeking a dynamic and self-motivated individual with the skills and experience to assist the Senior Chief Building Services Technician in all routine plant and services with particular remit to ensure continued operation of facilities serving the BioFacility at our main building located in the Centre of Cambridge. The building hosts approximately 200 researchers from a variety of Institutes and Departments. The post is part-time, 25 hours per week.

As well as daily planned maintenance, checking the functioning of the plant and interrogating the building management control systems, there will be a considerable degree of fault finding and troubleshooting. You will assist in a planned and breakdown (24hr) maintenance service for all mechanical and electrical services within the building pertaining to the running of the Institute's BioFacility.

You should be able to work both independently and as part of team and have good communication skills for interacting with contract staff. Familiarity with health and safety issues is also required. You should have recognised industry qualifications along with extensive experience in the successful maintenance of sophisticated plant and related services. A suitable steam qualification is desirable.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a security check.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is Thursday 03 September 2015.

Informal enquiries about the post are also welcome via email on jobs@stemcells.cam.ac.uk.

Interviews will be held on Friday 11 September 2015. If you have not been invited for interview by 8 September 2015, you have not been successful on this occasion.

Please quote reference PS06463 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Aug 04, 2015.

A position is open for a postdoctoral research associate based in the Evolution and Diversity Group at Department of Plant Sciences at the University of Cambridge, under the supervision of Dr Samuel Brockington.

Candidates must have, or be close to finishing, a PhD in a relevant biological discipline and will have an excellent background in molecular genetics and plant physiology. A strong grounding in evolutionary biology will be useful. Experience working with model bryophytes, especially the model liverwort Marchantia polymorpha is especially desirable. Experience in designing and implementing large-scale mutagenesis screens will be valuable. An ability to both work independently and communicate effectively is required. The candidate will have a strong publication record, including first author publications in high quality peer-reviewed journals.

The appointee will work within a project looking at the evolution of homiohydry in early land plants, specifically looking at the molecular genetic changes that underpin the evolution of the cuticle across the algal-land plant divide. The appointee will make use of candidate gene approaches, and mutagenesis screens coupled with transcriptomic analyses and physiological assays to dissect the function of the cuticle in early land plants. The appointee will 1) conduct and coordinate research, 2) interact closely with a bioinformatican, 3) interact with and mentor talented undergraduate and graduate students, 4) participate in lab meetings, and 5) write up results from experiments for publication in a timely manner.

The salary range if appointed as a Postdoctoral Research Associate is £28,695 - £37,394 per annum and the salary range if appointed as a Research Assistant is £24,775 - £28,695 per annum with promotion to Postdoctoral Research Associate on attainment of PhD.

Fixed-term: The funds for this post are available for up to 2 years in the first instance. The role is available immediately and candidates must be available to start work by January 2016 at the very latest.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. For further information contact Dr Sam Brockington (sb771@cam.ac.uk)

Please quote reference PD06788 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Clinical Director of Small Animal Surgical Services

From Jobs at the University of Cambridge. Published on Aug 04, 2015.

The Queen's Veterinary School Hospital (QVSH) is seeking a highly experienced small animal specialist to direct and expand clinical activities in small animal surgery, with a particular emphasis on orthopaedic surgery. This is an outstanding opportunity for a senior surgeon to manage and develop the Small Animal Surgery programme in line with the Hospital strategy while still practising surgery. This will be a full-time position that will combine clinical and managerial responsibilities, and will also allow the successful applicant to participate in didactic teaching, the supervision of clinical training scholars, and in clinical research activities.

The Small Animal Surgery programme is composed of Orthopaedic and Soft Tissue services, with four European board-certified surgeons (three academic-track and one clinical-track), three senior clinical training scholars and a team of 5 theatre nurses. The new post of Clinical Director of Small Animal Surgery has been created to develop the Small Animal Surgery programme and to strengthen the links between clinic and research. The Clinical Director will report to the Head of Department and will play an important role in developing and implementing clinical strategy through involvement with the Hospital Strategy and Management Committees in QVSH. The Clinical Director will work closely with the recently appointed, research-intensive Professor of Small Animal Surgery (Professor Matthew Allen).

Candidates for this position should be board-certified by the European and/or American College of Veterinary Surgeons, or recognised as a Specialist in Small Animal Surgery by the Royal College of Veterinary Surgeons (RCVS). Preference will be given to candidates with a track record of management and leadership at a senior clinical level, as well as to those with experience in teaching/training clinical veterinary students, interns and residents.

Candidates must be a Member of the Royal College of Veterinary Surgeons, or hold a veterinary degree that is registerable with the RCVS.

Further information: follow further particulars link in advertisement on University of Cambridge website: http://www.jobs.cam.ac.uk/

Informal enquiries: Professor Matthew Allen, 01223 337642, mja1000@cam.ac.uk

Further information about the Department: www.vet.cam.ac.uk

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload a full Curriculum Vitae and a brief statement about how your experience fits this role in the upload section of the online application.

Closing date: 20 September 2015

Interview date: 12 October 2015

Please quote reference PP06801 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Post-doctoral research associates - Chromatin and transcription regulation

From Jobs at the University of Cambridge. Published on Aug 03, 2015.

Post-doctoral Research Associate positions are available to join Professor Julie Ahringer's laboratory to study the regulation of chromatin in development and gene expression using the C.elegans model system. Experimental and computational positions are available.

Our research programme uses the powerful model organism C.elegans for uncovering general principles of eukaryotic chromatin regulation, focusing on transcription regulation and genome organisation in a developmental context. Projects include investigating mechanisms of enhancer function, the formation and regulation of chromatin domains, and chromatin regulation in developmental transitions. Our laboratory addresses these questions using a combination of wet-lab and computational approaches, applying high-throughput sequencing and directed methods to analyse gene expression and epigenetic state and function in wild-type and mutant animals and tissues (see http://www.gurdon.cam.ac.uk/research/ahringer for more information).

Successful candidates will be highly motivated and organised individuals with a PhD in a relevant area, excellent verbal and written communication skills as evidenced by publications in internationally recognized peer-reviewed journals, and the ability to work both independently and as part of a team. Expertise in a broad range of molecular biology techniques or in bioinformatics/computational analyses is essential. Previous experience in investigating transcription, epigenetic control of gene expression, and/or computational analyses is desirable.

The Gurdon Institute is located in the heart of the city of Cambridge, and is part of the University's School of Biological Sciences. It is a world-renowned centre in developmental and cellular biology and cancer research. Supported by funding from the Wellcome Trust and Cancer Research UK, it benefits from state-of-the-art facilities including bioinformatics, media preparation and animal husbandry. It provides the best atmosphere for research and a vibrant environment that facilitates the interactions and collaborations between scientists within the Centre and within Cambridge. Its postdoc association not only encourages scientific and social interactions but also provides career development and teaching opportunities.

Limited funding: The funds for this post are available until 30 November 2018 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applications should include a CV and a covering letter explaining your interest in this post. Informal inquiries can be addressed to Julie Ahringer at (j.ahringer@gurdon.cam.ac.uk). Please quote reference PR06786 on your application and in any correspondence about this vacancy. Interviews will take place during the week commencing 14th September 2015.

The University values diversity and is committed to equality of opportunity. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Professorship of Immunology

From Jobs at the University of Cambridge. Published on Aug 03, 2015.

The Board of Electors to the Professorship of Immunology invite applications for this Professorship from persons whose work falls within the general field of the Professorship to take up appointment on 1 October 2016 or as soon as possible thereafter.

Candidates will have an outstanding research record of international stature in Immunology and the vision, leadership, experience and enthusiasm to build on current strengths in maintaining and developing a leading research presence. They will hold a PhD or equivalent postgraduate qualification.

Standard professorial duties include teaching and research, examining, supervision and administration. The Professor will be based in Cambridge. A competitive salary will be offered.

Further information is available at: www.admin.cam.ac.uk/offices/academic/secretary/professorships/ or contact the Academic Secretary, University Offices, The Old Schools, Cambridge, CB2 1TT, (email: ibise@admin.cam.ac.uk).

Applications, consisting of a letter of application, a statement of current and future research plans, a curriculum vitae and a publications list, along with details of three referees should be made online no later than 14 September 2015.

Informal enquiries may be made to Professor G L Smith gls37@cam.ac.uk

Please quote reference PK06779 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research and Engagement Co-ordinator

From Jobs at the University of Cambridge. Published on Aug 03, 2015.

An exciting opportunity for a Research & Engagement Co-ordinator has become available within the Department and we wish to appoint to this role from 1 December 2015 or as soon as possible after that date. The role is funded for 5 years in the first instance.

This role will work in close liaison with the Research Director (a Professor in the Department) to support and develop the Department's research strategy, and to foster the research community. The role holder will provide a service to all academic staff in the Department, providing high quality support to individuals developing both particular research applications and future research profiles. A significant amount of work outside the Department may be required, interacting with and providing intelligence about traditional funders and beyond, enhancing research and engagement with industry, and suggesting ways to expand this in the Department.

This is a key administrative role in the Department. It reports to the Departmental Secretary and will require close teamwork with the Assistant Secretary (Finance & Research) and the Assistant Secretary (Human Resources) in order to ensure that projects progress at the post-activation stage within the sponsor's contractual terms and that changes and amendments are made correctly; and the role will work closely with the Research Support Assistant and provide direct supervision and training for that role.

The successful candidate will be educated to first degree level, preferably in a science discipline, a postgraduate degree in a science discipline is desirable. The successful candidate will have significant experience of research or administration in a higher education environment or similar type of large research organisation. Excellent written and oral communication skills are essential, as is the ability to build strong working relationships with a variety of people.

If you have any questions about this vacancy or the application process, please contact Natalie Wills, nw366@cam.ac.uk

To find out more about the Department please visit: www.vet.cam.ac.uk

Further information about the role can be found below.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Closing date for applications: 13 September 2015

Interview date: 6 October 2015

Please quote reference PP06785 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Postdoctoral Research Associate in Protein Engineering: Directed Evolution and Mechanistic Analysis (Fixed Term) (Fixed Term)

From Jobs at the University of Cambridge. Published on Jul 31, 2015.

A postdoctoral position is available for 9 months (with a possibility of extension) from 15 September 2015 (or later) to work with Florian Hollfelder based in the University of Cambridge, Department of Biochemistry, Central Cambridge on in vitro directed evolution and mechanistic analysis of promiscuous enzymes (i.e. enzymes with multiple activities).

We will base directed evolution of new generalists and specialists on measurement of fitness landscapes of randomised protein populations: such distribution functions for multiple activities will be gathered by ultrahigh-throughput screening of >106 clones in picolitre droplet compartments during in vitro evolution cycles, followed by systematic characterization of multiple fitness traits such as expression level, stability or reaction kinetics. We will also test how directed evolution of thermostable analogs differs frm that of enzymes with low-temperature activity peaks. These approaches will enable a dynamic picture of protein evolution at various levels from transition state recognition, protein biophysics to population genetics. The work is part of the EU Marie-Curie IAAP network 'HotDrops' (http://hotdrops.cbm.uam.es/index.php)

Candidates should have skills in protein engineering, directed evolution, kinetic analysis of enzyme catalysis, chemical biology techniques, molecular biology techniques, biophysical analysis of proteins.

Candidates should have a PhD in a relevant subject/have recently submitted or the equivalent.

Fixed-term: The funds for this post are available for 9 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries can be made to Dr Florian Hollfelder - fh111@cam.ac.uk. Any enquiries relating to the application process please contact the personnel secretary - personnel@bioc.cam.ac.uk

Please quote reference PH06749 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Cardiovascular toxicology PhD Studentship (Fixed Term)

From Jobs at the University of Cambridge. Published on Jul 31, 2015.

Developing a human model of drug-induced vascular injury to determine the mechanisms of cardiovascular toxicity

An exciting opportunity has arisen for a PhD student to work on a project funded by AstraZeneca in the research group led by Dr Matthew Harper at the Department of Pharmacology, University of Cambridge (http://www.phar.cam.ac.uk/research/harper). The project will be carried out in collaboration with Dr Kelly Gray in the Translational Safety Group, Drug Safety and Metabolism at AstraZeneca in Cambridge.

A new drug must be effective but also safe. Cardiovascular toxicities, including vascular damage, thrombosis and heart failure, are a major reason for drugs to be withdrawn from development or after approval. However, drugs associated with vascular damage often show little or no systemic effects in cardiovascular safety studies. Therefore, there is a need for new models that accurately predict human vascular injury.

In this project we will investigate how toxic drugs affect the interactions between vascular cells and circulating blood cells, and how this leads to vascular damage, inflammation and thrombosis. We will use a broad range of techniques, including high resolution imaging, cell culture, myography and flow cytometry, to develop a new ex vivo model of drug-induced vascular damage in human blood vessels. In this way we will provide new mechanistic insights into how drugs cause blood vessel damage.

Applicants should have or expect to obtain a minimum of a UK II.i Honours Degree (or equivalent) in Pharmacology or a related subject including Cellular or Molecular Biology, Physiology. Competition is intense and successful applicants are likely to demonstrate high academic achievements. We are looking for a highly motivated, enthusiastic individual, capable of thinking and working independently, with an interest in, and possibly some knowledge of, vascular biology and drug development or toxicology.

Eligibility: To be eligible for a full award (stipend and university fees) a student must have (a) settled status in the UK, meaning they have no restrictions on how long they can stay; (b) been 'ordinarily resident' in the UK for three years prior to the start of the studentship. This means they must have been normally residing in the UK (apart from temporary or occasional absences), and (c) not been residing in the UK wholly or mainly for the purpose of full-time education (this does not apply to UK or EU nationals). EU citizens who have not been resident in the UK for three years may only be eligible for a fees-only award.

Funding: Full funding covering the University Composition Fee, Maintenance (currently £14,057 pa), an allowance for conference attendance and consumables is provided for up to 4 years, with effect from 1 January 2016.

Informal enquiries about the position can be made to Dr Matthew Harper (mth29@cam.ac.uk).

To apply, please e-mail the following at phar-gradadmissions@lists.cam.ac.uk:

(A) your CV with full contact details of 2 academic referees (max two A4 pages), (B) your academic transcript(s), and (C) a cover letter (max two A4 pages) highlighting (a) your background/research interests, (b) how you will fit in with this project, (c) what you hope to achieve in the programme and your career aspirations beyond the programme, and (d) why the Department of Pharmacology, University of Cambridge is the best place for you to pursue your interests.

Applications will be assessed as and when they are submitted.

Please quote reference PL06757 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jul 31, 2015.

A position is available for a highly motivated post-doctoral research assistant/associate working on the regulation of photosynthesis gene expression.

The successful applicant will join Professor Julian Hibberd's laboratory in the Department of Plant Sciences at the University of Cambridge. The project will focus on understanding how gene expression in different cell-types of the rice leaf is regulated, and thus inform our understanding of how tissues from multicellular eukaryotic function. Rice will be used as the model for this work, and so findings will be relevant to one of the major crops of the world.

The position is available immediately. The successful candidate will have a strong background in plant molecular biology, including a PhD in a relevant area (or have submitted a PhD by the time of appointment). Experience with synthetic biology, isolation of specific cells or their organelles, and deep sequencing technologies will be advantageous.

Fixed-term: The funds for this post are available for 18 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. For further information contact Prof Julian Hibberd (jmh65@cam.ac.uk)

Please quote reference PD06761 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate - Bioinformatician (Fixed Term)

From Jobs at the University of Cambridge. Published on Jul 31, 2015.

Biological Network Analysis using High Throughput Data.

This is an exciting opportunity for someone with a strong background in statistics and data analysis to play a leading role in developing and applying methodology for the analysis of high throughput data (e.g. transcriptomic, proteomic, metabolomic) in order to understand network dynamics. The post holder will work with data from two projects in which a perturbation causes a change in the biological network. The desired practical outcome is improvement of algal biofuel or crop productivity.

The post holder will be part of the Departmental Bioinformatics Group led by Dr Krys Kelly, working with Professors Alison Smith and Alex Webb in Plant Sciences and collaborators in Sheffield, Scotland and India. The Bioinformatics Group currently consists of 6 people developing statistical methodology and analysing many different types of genome-wide data. The post holder will also work closely with experimentalists in the Smith and Webb labs.

Applicants should have a PhD and substantial experience of data analysis and a programming language (e.g. R, Matlab, Python). Experience of high throughput data including 'omics technologies, such as RNAseq and ChIPseq would be beneficial.

Fixed-term: The funds for this post are available for up to 2 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. For further information contact Dr Krys Kelly (kak28@cam.ac.uk)

Please quote reference PD06754 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

General Office Receptionist (Part Time)

From Jobs at the University of Cambridge. Published on Jul 31, 2015.

We are looking to appoint a permanent General Office Receptionist from 1st October 2015 or as soon as possible from that date.

The role is key to the smooth running of the Department, and supports the wider Academic Support and HR teams in the Department. The role is responsible for the busy Reception area/General Office, which provides general services to staff and students in the Department, is the first point of contact for all (non-Hospital) visitors and tradesmen to the Department, and is a first point of contact for telephone calls from within the University and from external callers. The Department has approximately 200 members of staff, 25 Clinical Training Scholars, 250 students, 40 researchers, 20 visiting scholars, and a steady daily flow of visitors and telephone callers.

The role reports to the Senior Secretary, and is responsible for providing a proactive and professional first-line service to staff and students, and for ensuring a positive first impression and service to visitors to the Department. The role is responsible for receiving, providing information to, and giving directions to visitors and callers to the Department, for postal and courier services into and out of the Department, for providing a photocopying service and for assisting with routine HR-related tasks.

This role will suit a well organised individual with excellent communication skills who is able to deliver a high level of customer service to all visitors to the Department.

This is a part time position working 33 hours 45 minutes per week Monday to Friday.

Informal enquiries should be directed to Natalie Wills: nw366@cam.ac.uk

To find out more about the Department please visit: www.vet.cam.ac.uk

Further information about the role can be found below.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Closing date for applications: 30 August 2015

Interview date: 17 September 2015

Please quote reference PP06771 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Human Anatomy Technical Co-ordinator

From Jobs at the University of Cambridge. Published on Jul 31, 2015.

Applications are invited for the interesting and varied post of Human Anatomy Technical Co-ordinator which supports our highly regarded medical student teaching programme in topographical anatomy (see www.pdn.cam.ac.uk/teaching/anatomy/index.shtml) through management of our Human Anatomy Dissection facility. You will oversee our special facilities, maintain responsibility for health and safety, supervise four members of Assistant Staff, undertake teaching administration, act as a budget holder for the facility, and promote compliance with the Human Tissue Act.

The successful candidate should have a BSc or equivalent in a biological subject, have considerable experience of running a biological laboratory and have a thorough understanding of health and safety management in a laboratory setting. You will be IT literate and have good organisational skills as well as supervisory experience. The ability to communicate well with a range of individuals is essential as are the capacity to problem solve and work with precision. Some understanding of human anatomy would be advantageous though applications are welcome from those with a strong biological sciences background with a willingness to learn.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please complete the online application as fully as possible.

For informal enquiries, please contact Dr Cecilia Brassett (cb457@cam.ac.uk) or Dr Helen Taylor (hlt37@cam.ac.uk).

The closing date for applications is midnight on Sunday 6 September 2015.

Please quote reference PM06074 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jul 28, 2015.

Applications are invited for a Post-doctoral Research Assistant/Associate position in the group of Professor Yka Helariutta at the Sainsbury Laboratory (SLCU), Cambridge University, to study cell wall biology of phloem.

The sieve elements of phloem are highly specialized cells adapted for long-distance transport. We are currently analysing their differentiation processes at a fine cell biological level. In this project we are investigating the morphogenesis of the cell wall features to sieve elements. We will focus on the molecular mechanisms of callose accumulation and sieve plate formation. We have several unique genetic materials available for the project. The successful candidate will utilise model plant systems such as Arabidopsis and Populus to develop independent lines of research by taking advantage of resources and unpublished data existing in the lab. The candidate will be provided with horticultural/technician support.

Candidates must have or be close to finishing a PhD in a relevant discipline (e.g. plant biology, plant biotechnology or related field). Previous plant cell biology experience and plant development experience in Arabidopsis is essential. Proficiency in standard molecular cloning as well as fluorescent microscopy techniques is also required, alongside experience in plant cell transformation and computer-based sequence analysis. Experience in cell wall biology, immunostaining or mutagenesis would be an advantage.

The successful candidate will be fully involved in the basic research whilst also writing up their research work for presentation and publication. The post holder may be required to assist in the supervision of student projects, provide instructions to students and deliver seminars relating to their research area.

Good communication skills are essential as the post holder will need to work well in a team and collaborate with other researchers in the Institute. Candidates would ideally have published or submitted papers in this area. Candidates should demonstrate a history of science communication (e.g. presentations, outreach activities, teaching).

The Laboratory provides a welcoming and collaborative environment with a wide-range of family-friendly benefits and development opportunities. More about the Sainsbury Laboratory, further information for the role and details of what the University offers to employees, can be found at: http://www.slcu.cam.ac.uk/.

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload a copy of your full CV, a supporting statement including your areas of interest and contact information of three referees.

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within three weeks of the closing date, please consider your application as unsuccessful on this occasion.

Please quote reference PT06713 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant (Fixed Term)

From Jobs at the University of Cambridge. Published on Jul 27, 2015.

The Centre for Family Research is leading an international research programme into how early family relationships shape infants' social and cognitive development. Key features of this study are the inclusion of fathers at each time-point (including a prenatal visit) and the use of detailed observations of parent-infant interactions. A recent Wellcome Trust Seed for Science Award has enabled us to extend the scope of this study in two ways:

1) Harnessing the power of new technology to obtain rich measures of parent-infant interaction (e.g., quantity and emotional tenor of talk).

2) Recruiting 50 new expectant parents whose transition to parenthood involves a stay in a Neonatal Intensive Care Unit (NICU), for example, following premature delivery.

The successful applicant will work as part of a team of at least 5 researchers led by Professor Claire Hughes (Deputy Director of the Centre for Family Research) and so will receive plenty of support and training. The applicant will, however, be expected to work independently in liaising with families, conducting home visits and carrying out office-based duties (e.g., coding videos). As the work entails visits with both mothers and fathers applicants must be willing to fit hours of work around family commitments - with regular work at weekends and/or evenings.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Interviews will be held on Friday 11th September 2015.

Please quote reference XJ06711 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant x 2 (Fixed Term) - Behavioural Neurophysiology of Reward, Risk and Decision Making (Neuroeconomics)

From Jobs at the University of Cambridge. Published on Jul 27, 2015.

Using awards from the Wellcome Trust and the European Research Council (ERC), we are aiming to fill one or two research assistant positions in behavioural neurophysiology and functional human neuroimaging. The positions are suitable for registering as PhD student at the University of Cambridge.

Our work investigates neuronal signals for fundamental behavioural variables underlying reward learning and economic decision making. We derive rationales, task designs and data interpretations from animal learning theory and economic decision theory, appreciate straightforward experimental tasks and thorough behavioural testing, perform closely related human neuroimaging studies, and collaborate with behavioural economists and experimental psychologists locally and internationally. We offer innovative projects for experimentally minded, theory driven, or general neuroscience / neuroeconomics candidates. Planned projects concern neuronal signals involved in individual and social economic decisions and value updating. We will study neuronal processing of reward, utility, risk, inequity and cooperation in the main reward structures including dopamine neurons, striatum, amygdala and orbitofrontal cortex. We combine the candidate's own ideas with demands of the grants.

Candidates should have a degree in a relevant subject, have experience in single cell behavioural neurophysiology (neuronal recordings, optogenetics), human fMRI neuroimaging, behavioural economics and/or quantitative experimental psychology in mammalian species. We appreciate excellent social, writing and computer skills (including preferably knowledge in Matlab).

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check), a health assessment and a security check.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applications should include CV, list of publications, half page description of research experience specific for the projects stated above (including computer skills), half page description of research interests and contact details of two referees. The closing date for applications is midnight on 15 September 2015; start date is flexible. Wolfram Schultz, Department of Physiology, Development & Neuroscience, University of Cambridge, UK, ws234@cam.ac.uk.

Please quote reference PM06720 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Senior Clinical Training Scholarship in Anatomical Pathology

From Jobs at the University of Cambridge. Published on Jul 22, 2015.

SCHOLARSHIP AWARD £ 21,690 Year One

The Scholarship is available from 1 December 2015, for one year in the first instance, renewable for periods of one year up to a total of three years. It is subject to an initial monitoring period of six months, and to review on an annual basis.

The Scholarship provides an outstanding opportunity to study for a postgraduate qualification, and it is expected that the Scholar will work towards the diploma exams of the European College of Veterinary Pathologists and/or the fellowship exams of the Royal College of Pathologists.

You will receive core training at the Queen's Veterinary School Hospital diagnostic pathology laboratory. You will be trained in diagnostic gross pathology and histopathology of all common domestic species with some additional exposure to zoo animal species and laboratory animals; will participate in the small-group teaching of veterinary students; and will undertake a research project. The training programme is approved by the European College of Veterinary Pathologists (ECVP), and the Royal College of Pathologists.

Applicants must be a Member of the Royal College of Veterinary Surgeons, or hold a veterinary degree qualifying them for membership. In order to comply with ECVP trainee registration requirements, the applicant must have worked or undergone training as a veterinarian in a field relevant to veterinary pathology for at least one year subsequent to graduation from veterinary school. A minimum of 12 months' experience of diagnostic pathology is desirable.

For informal discussion about the position, please contact Professor Alun Williams, 01223 337640, aw510@cam.ac.uk or Dr Fernando Constantino-Casas, fc307@cam.ac.uk

Closing date: 1 September 2015

Interview date: 14 September 2015

Application form (SCTS1) and information pack: contact Melissa Large on 01223 337055, or download from http://www.vet.cam.ac.uk/news/

Completed application form, curriculum vitae and covering letter: send to Melissa Large, Department of Veterinary Medicine, Madingley Road, Cambridge, CB3 OES, or email vetmed@hermes.cam.ac.uk

Please quote reference PP06682 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate x 3 (Fixed Term)

From Jobs at the University of Cambridge. Published on Jul 20, 2015.

We are looking for three motivated, ambitious and independent post-doctoral researchers to join an interdisciplinary research project on Alzheimer's disease, developing novel models of human white matter, single-molecule fluorescence techniques, sensitive biosensors and cutting-edge optical imaging methods. The project is ambitious, aiming to make step changes in human stem cell development, tissue culture engineering, biosensor generation and understanding of Alzheimer's disease.

This focused collaborative project brings together the expertise of:

Dr. Káradóttir (Wellcome Trust - MRC Stem Cell Institute: http://www.stemcells.cam.ac.uk/researchers/principal-investigators/dr-ragnhildur-thra-kradttir),

Dr. Lee (Dept. of Chemistry: http://www.ch.cam.ac.uk/person/sl591),

Prof. Spillantini (Dept. of Clinical Neuroscience: http://www.brc.cam.ac.uk/principal-investigators/maria-spillantini/),

Dr. Coleman (John van Geest Centre for Brain Repair: http://www.neuroscience.cam.ac.uk/directory/profile.php?mcoleman),

Prof. Brayne (Institute of Public Health: http://www.iph.cam.ac.uk/about-us/key-people/carol-brayne/),

Prof. Brown (Dept. of Biochemistry: http://www.bioc.cam.ac.uk/people/uto/brown),

and Prof. Hall (Dept. Chemical Engineering and Biotechnology: http://www.ceb.cam.ac.uk/directory/lisa-hall), all based at the University of Cambridge.

This multi-departmental arrangement provides an excellent environment for research and career development, as the post holders will benefit from the resources and expertise of biological, physical and medical sciences in this multidisciplinary project.

Requirements:

We are looking for candidates that hold a PhD, (1) in the field of neuroscience/biochemistry/stem cell biology/medicine, and (2) candidates which hold a PhD in the field of chemistry/bioengineering/engineering/biophysics. Candidates with experience in cross-disciplinary research are particularly encouraged to apply.

The successful candidates will have a strong publication record and enjoy ambitious projects at the frontiers of neuroscience and biotechnology. We are specially looking for candidates that are self-motivated, collaborative with effective communication skills and enjoy working in a team. Proven capacity to design, execute, and interpret experimental data is essential.

Applicants should have obtained (or expect to obtain) one of the following:

(1) a PhD in neuroscience/biochemistry/stem cell biology/medicine. Experience in tissue culture methods (such as deriving neuronal cells from human IPSCs), fluorescence imaging or neurodegenerative disease, is highly advantageous.

(2) a PhD in biophysics, physical chemistry, photonics, optics or related disciplines. Experience with single-molecule fluorescence techniques, generation of biosensors or electrochemical engineering would be highly advantageous. Candidates should have a keen interest in applying physical methods to complex biological systems, although no prior knowledge of neurodegenerative disease or biology is required, and enjoy working in a highly multidisciplinary environment.

(3) a PhD in either physical or life sciences, with a solid background in cross-disciplinary research, particularly in neuroscience and biophysics or bioengineering. Experience with fluorescence techniques, generation of biosensors or electrochemical engineering, electrophysiology, or tissue culture methods/engineering development, would be highly advantageous.

Start date is flexible but can be as early as October 2015.

Fixed-term: The funds for this post are available until 30 September 2018 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is Monday 31 August 2015.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Informal enquiries about the post are also welcome via email on jobs@stemcells.cam.ac.uk.

Interviews will be held in mid-September 2015. If you have not been invited for interview by 15 September 2015, you have not been successful on this occasion.

Please quote reference PS06656 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.