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Chief Research Laboratory Technician

From Jobs at the University of Cambridge. Published on May 22, 2015.

Applications are invited for a chief research laboratory technician to support projects within the laboratories of Professor Sir Tom Blundell and Professor Ben Luisi. The role holder is primarily concerned with the management and smooth running of these two large research groups in the department, both working in the field of Structural Biology. The role holder has responsibilities for the Biophysics and Crystallographic X-Ray facilities. For more information please visit the Professor Sir Tom Blundell and Professor Ben Luisi group webpages using the links below:

http://www.bioc.cam.ac.uk/people/uto/blundell

http://www.bioc.cam.ac.uk/people/uto/luisi

The role holder will act as the main point of day-to-day contact for all group members in the laboratories and is responsible for support to a diverse personnel including post-docs, Erasmus and Marie Curie students, Ph.D. and M.Phil students, 3rd and 4th year undergraduates and visitors. The role holder will convene, minute and chair regular group meetings concerning general laboratory matters, organisation and safety and ensure agreed actions are followed up.

The role is responsible for all purchasing for the groups and will maintain comprehensive records and analyses of purchasing trends. The role holder also manages the groups' research grants and ledger accounts and will be able to balance budgets and liaise with accounts teams to resolve anomalies. Assisting the group heads with grant proposals is a further requirement.

Ensuring the laboratories are in good order with regular checks for a safe working environment is paramount and the role holder will ensure the laboratories operate safely and in accordance with the Department and University Health and Safety Rules and guidance. They will maintain and review all safety records, laboratory documentation and chemical databases.

The role holder will carry out first line maintenance and training for new users on equipment used by the research groups. They will arrange repairs and assist with demonstrations and will assist facility managers of the Biophysics and Crystallographic X-Ray by preparing invoices and checking and re-charging equipment usage for these areas.

Skills and qualifications required: a relevant degree with significant laboratory management exposure. Knowledge of a range relevant equipment and the ability to provide first line support together with good IT skills. Strong communication skills, the ability to work as part of a team and carry out a number of versatile tasks as required, ability to work to deadlines and attention to details. Previous experience in a biological background would be advantageous.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made to Debra Manning - dam24@cam.ac.uk

Please quote reference PH06164 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Technicians (Fixed Term and Maternity Cover)

From Jobs at the University of Cambridge. Published on May 22, 2015.

Applications are invited for two full-time Senior Research Technician posts in the laboratory of Professor Steve Jackson (http://www2.gurdon.cam.ac.uk/~jacksonlab) at the internationally renowned Gurdon Institute in the Centre of Cambridge.

The successful candidates will become part of a team focused on DNA repair and genome stability. The candidates will have the opportunity to significantly contribute to exciting new screening projects involving next generation sequencing and subsequent analysis/characterisation. Under the supervision of a postdoctoral researcher the candidates will carry out a variety of molecular and cell biology techniques. Activities will include preparation of reagents and maintenance of lab stocks, whilst assisting in the day-to-day running and organisation of the lab.

Post one: is funded for one year in the first instance but may be extended if further funding becomes available. Post two: is to provide maternity cover and is for a fixed-term of 12 months or the return of the post holder whichever is the earlier.

Applicants should have an HNC in Biological Sciences or equivalent, preferably with experience working with yeast. Good attention to detail and willingness to perform some repetitive tasks would be advantageous.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

If you have any queries about the vacancies, please email jobs@gurdon.cam.ac.uk

Please quote reference PR05936 on your application and indicate whether you are applying for post 1 or post 2 in any correspondence about this vacancy.

Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes. The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate in Bioinformatics for Mass Spectrometry (Fixed Term)

From Jobs at the University of Cambridge. Published on May 21, 2015.

Postdoctoral positions in lipidomics and metabolomics

A postdoctoral research associate position is available for up to three years (12 months in the first instance) to work in the laboratory of Dr J.L. Griffin, University of Cambridge, Department of Biochemistry, Tennis Court Road, Cambridge. The project will develop tools to measure lipid species in conjunction with ion mobility, an exciting development in mass spectrometry which will allow the separation of ions according to their cross sectional area as well as their mass to charge ratio. It is envisaged that the successful candidate will work alongside an experienced mass spectrometrist involved in method development, whilst developing new software tools for processing the data obtained.

We are looking for an bioinformatician with experience in processing biological mass spectrometry data or other relevant experience such as experience in signal processing. The work is a collaborative project between Dr. J.L Griffin (Dept of Biochemistry), Prof. Michael Wakelam (Babraham Institute) and Agilent technology. As part of this project the research associate will have access to a state of the art ion mobility Q-ToF LC-MS to develop new tools for lipidomics, and building on our work in diabetes and metabolic diseases (Griffin) and cancer (Wakelam) use the instrument to explore cellular signalling in these disease processes. Some examples of this work can be found in Roberts LD et al., Lancet Endocrinology, 2014; Roberts LD et al., Methods in Enzymology, 2014; Zhang Q & Wakelam MJ, Adv Biol Regul 2014.

Skills required are bioinformatics for metabolomics or proteomics and a general interest in metabolism and disease processes in mammals Previous work in metabolomics and/or lipidomics would be an advantage but we will consider relevant experience in other areas such as aspects of signal processing

Applicants should have a PhD or are about to submit or have the equivalent in a relevant science.

Fixed-term: The funds for this post are available for 12 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made to Dr J.L Griffin - jules.griffin@mrc-hnr.cam.ac.uk

Please quote reference PH06024 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate, Biology and Disease Mechanisms of Drosophila Axonal Endoplasmic Reticulum (Fixed Term)

From Jobs at the University of Cambridge. Published on May 20, 2015.

We wish to appoint a postdoctoral research associate, funded by a BBSRC grant, to work on formation and function of axonal endoplasmic reticulum, and the roles of spastic paraplegia gene products in this.

Applicants should have a PhD in a biological science, and previous experience or strong interests in model organism genetics, neuronal cell function, light or electron microscopy, molecular biology, and bioinformatics.

Informal enquiries may be made to Dr. Cahir O'Kane, c.okane@gen.cam.ac.uk, http://www.gen.cam.ac.uk/research-groups/okane

Fixed-term: The funds for this post are available from 1 January 2016 until 31 December 2017 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Your application should include your CV and a covering letter, explaining why you are suited to the position.

Please quote reference PC06137 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Senior Research Technician (Fixed Term)

From Jobs at the University of Cambridge. Published on May 20, 2015.

Applications are invited for a motivated and experienced Senior Research Technician to join a team investigating the neural mechanisms underlying the regulation of emotion, of relevance to anxiety and depression. The postholder will be based in a facility in West Cambridge. The main duties of the post will include assisting in the conduct of neuropsychological experiments and data collection, as well as in the preparation and histological assessment of tissue samples. You will be also be responsible for maintaining wet lab areas in the facility, ensuring stocking levels and maintaining cleanliness and ensuring compliance with standard operating procedures.

Applicants should have a relevant HNC/degree, together with substantial relevant laboratory based and animal technology experience. A Home Office Personal Licence is a requirement, with certification for Module 4 an advantage.

Fixed-term: The funds for this post are available until 31 March 2020 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a security check.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please complete the online application as fully as possible. The closing date for applications is midnight on Thursday 11 June 2015.

Please quote reference PM06142 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Administrative Assistant (Fixed Term)

From Jobs at the University of Cambridge. Published on May 20, 2015.

Applications are invited for the position of Administrative Assistant to provide support across the administrative functions of the Sainsbury Laboratory, with particular emphasis on Human Resources (HR) and Health & Safety administration.

Candidates must have a good level of education and experience in a secretarial/administrative post, ideally within a higher education environment. A background principally in either HR or Health & Safety is essential, alongside an enthusiasm and willingness to learn new skills. The Institute will be fully supportive of all the necessary training.

The successful candidate will be highly competent in standard software packages, eg Word, Excel, Access, Outlook and have excellent keyboard skills. A working knowledge of SharePoint would be advantageous, alongside experience of providing committee support.

The successful candidate will have excellent interpersonal, communication and organisational skills, with a positive, service-oriented, can-do attitude. They will be able to work independently and have a pro-active approach to troubleshooting and problem solving. Much of the work is of a confidential nature and so the ability to maintain confidentiality is paramount. Attention to detail and effective time management are also essential.

The Laboratory provides a welcoming and collaborative environment with a wide-range of family-friendly benefits and development opportunities. More about the Sainsbury Laboratory, further information for the role and details of what the University offers to employees, can be found at: http://www.slcu.cam.ac.uk/.

The post is available immediately.

Fixed-term: The funds for this post are available until 31 December 2016 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within three weeks of the closing date, please consider your application as unsuccessful on this occasion.

Please quote reference PT06143 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on May 19, 2015.

New drug targets for TB through prediction/investigation of impact of resistance mutations

Applications are invited for a post-doctoral research associate position that will form part of the Cambridge cohort of MM4TB, the EU FP7 collaboration in Tuberculosis.

The post holder will work in the laboratory of Professor Sir Tom Blundell in the University of Cambridge, Department of Biochemistry, Central Cambridge, working collaboratively with partners and to advise on the use of Credo, a database of protein-ligand interactions, and Chopin, our database of the M. tuberculosis structural proteome. The post-holder will also take the lead in rewriting the computer program SDM, which uses statistical analyses of amino acid substitutions in proteins of known structure to analyse the impacts of polymorphisms identified by gene sequencing. The post-holder will also collaborate with colleagues to integrate the computer program with mCSM which uses machine learning for analyses of effects of polymorphisms on protein stability, protein-protein, protein-nucleic acid, and protein-ligand interactions.

The successful applicant should have a proven knowledge of computer programming languages and should have written computer code for structural bioinformatics in the past.

Applicants should have a PhD in structural bioinformatics or computational biology or the equivalent with knowledge of molecular and structural biology.

Fixed-term: The funds for this post are available for 6 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Enquiries should be directed to Professor Sir Tom Blundell, tlb20@cam.ac.uk

Please quote reference PH06072 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on May 19, 2015.

A position is open for a postdoctoral research associate as part of the OpenPlant Synthetic Biology Research Centre at the University of Cambridge, under the direction of Dr. Jim Ajioka based in central Cambridge.

The appointee will develop a research project based on the development of new synthetic biology tools for engineering the plastid genome in the model plant Marchantia polymorpha. Work with Marchantia allows streamlined approaches to genome modfication, secondary metabolism and morphogenetic engineering. We are looking for a highly motivated post-doctoral scientist to work in this area. The position is available as a full-time position for 30 months.

The successful candidate will have a strong background in plant molecular biology, yeast genome engineering or synthetic biology, including a PhD in a relevant area or expect to obtain one shortly. Experience with synthetic biology approaches, handling large DNAs, plant or yeast molecular biology will be advantageous.

Where the successful applicant does not yet have a PhD, he/she will normally be under-appointed as a Research Assistant in a Research Associate post (on the understanding that he/she will be appointed as a Research Associate upon successful completion of his/her PhD). The higher Research Associate salary should be backdated to the submission date of their thesis.

OpenPlant is a BBSRC-EPSRC funded Synthetic Biology Research Centre. It is based in the United Kingdom and is a collaboration between the University of Cambridge and the John Innes Centre and The Sainsbury Laboratory, Norwich. The OpenPlant SBRC is focused on the development of open foundational technologies for plant synthetic biology and their application for engineering new traits in crop systems. OpenPlant will (i) fund interdisciplinary efforts in plant Synthetic Biology, to explore novel foundational technologies and applications, build shared resources and provide a point of exchange for young scientists and entrepreneurs; (ii) promote two-tier intellectual property models that will promote sharing of DNA components and freedom-to-operate for commercial applications of plant synthetic biology, and (iii) address responsible innovation, and explore the potential wider impacts of synthetic biology on sustainable practices in agriculture, bioproduction, land use and environmental conservation. (http://www.openplant.org)

The ability to work both as part of a team, and independently, coupled with excellent communication, organizational and problem solving skills are required. The duties/responsibilities of this post include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures as outlined on the Further Information Document

Applicants should provide a CV, the filename of which should be "CV-followed by your name", including contact details of two or more referees, and a covering letter addressing the selection criteria.

For further information contact Dr Jim Ajioka (ja131@cam.ac.uk)

Fixed-term: The funds for this post are available for 30 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK05505 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on May 19, 2015.

Applications are invited for a Research Associate position starting from August 2015.

The successful candidate will join Dr Colin Crump's laboratory to investigate the role of viral tegument proteins of alphaherpesviruses during early stages of infection. The post will be within the Department of Pathology, University of Cambridge, and located on the Cambridge Biomedical Campus.

Candidates should have a PhD, or expect to obtain one shortly, and have a track record of success in virology and/or cell biology research. Relevant experience in cell culture, molecular biology techniques and fluorescence microscopy imaging is essential. Prior experience in handling biosafety level 2 material, mass spectrometry-based proteomics techniques, or super-resolution microscopy would be advantageous.

The ability to work both independently and as part of a team, coupled with excellent communication, organizational and problem solving skills are required. The duties/responsibilities of this post include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures as outlined in the Further Information Document.

Where the successful applicant does not yet have a PhD, he/she will normally be under-appointed as a Research Assistant in a Research Associate post (on the understanding that he/she will be appointed as a Research Associate upon successful completion of his/her PhD). The higher Research Associate salary should be backdated to the submission date of their thesis.

Fixed-term: The funds for this post are available for 3 years or until 31 July 2018 in the first instance.

The closing date for all applications is Monday 22nd June, 2015 and interviews will be held in the week of Monday 29th June, 2015.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should provide a CV, the filename of which should be "CV-followed by your name", including contact details of two or more referees, and a covering letter addressing the selection criteria.

Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK06131 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Apprentice Laboratory Technician (Fixed Term)

From Jobs at the University of Cambridge. Published on May 18, 2015.

An Apprentice Laboratory Technician is required to work in the University of Cambridge, Department of Biochemistry. The successful applicant will undertake a structured training programme rotating through a number of laboratories over the three year apprenticeship to provide technical support for the Department's research, teaching and infrastructure. You will assist both researchers and classroom staff with basic laboratory duties including operation of laboratory equipment and preparation of working solutions for experiments.

The successful applicant will be passionate about science and technology and will be required to undertake an appropriate day-release course at NVQ Level 2 and Level 3. Ideally you will be computer literate, able to communicate effectively, enthusiastic, have the ability to express clearly technical details and show evidence of practical problem-solving skills.

Skills required include the ability to concentrate for extended periods, good manual dexterity and the ability to learn quickly.

Applicants should hold or be expected to achieve GCSEs at Grade C or above (or equivalent) in Mathematics, English and a science-based subject as a minimum.

Fixed-term: The funds for this post are available for up to 3 years in the first instance.

To apply for this vacancy please visit: https://goo.gl/eCWEWB This will take to the role on the National Apprentice website, you will then be able to apply on-line.

For all informal enquiries please email Debra Manning - dam24@cam.ac.uk.

Please quote reference PH06127 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Client Services Administrator (Part Time, Fixed Term)

From Jobs at the University of Cambridge. Published on May 18, 2015.

UNIVERSITY OF CAMBRIDGE DEPARTMENT OF VETERINARY MEDICINE West Cambridge Site

Part time 22.5 hours per week, Monday to Friday

Limit of Tenure 3 years in the first instance

The Queen's Veterinary School Hospital is looking for a pro-active, flexible team player to work in the Reception area of both the Small and Large Animal sections as part of the Hospital Administration Team, some flexibility may be required. This is a part time position working Monday to Friday from 10.00am to 3.00pm, with half an hour for lunch each day.

The following are essential :-

Educated to 'A' level standard or with significant experience in a very similar environment. Competent in Microsoft software packages e.g. Word, Excel and Outlook . Ability to work with Hospital management information system, paging systems. Ability to prioritise own workload. Attention to detail. Excellent communication skills with the ability to work with staff at all levels of the organisation. A positive service-oriented "can do" attitude. The ability to work on own initiative, contribute effectively to the team as a whole, and be able to demonstrate a proactive approach to troubleshooting and problem solving. Professional confidence to engage with clients in difficult situations e.g. unpaid bills or death of pet. Experience of working in an administrative role based in either a veterinary or clinical organisation. The roleholder will come into contact with animals - therefore must not have a physical or emotional response which precludes this. Willing to undertake training when necessary

The following are desirable:

Office/business management qualification.
Accounts qualification.
Understanding of the teaching /research element of University's role.

Closing Date 28th May 2015

Interviews will be held: 9th June 2015

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For informal enquiries please contact Kate Smith email: kw306@cam.ac.uk Further information is available via the link below. To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PP06122 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Chief Research Laboratory Technician (Fixed Term)

From Jobs at the University of Cambridge. Published on May 18, 2015.

We are looking for an experienced, enthusiastic technician to join the Centre for Trophoblast Research, a multidisciplinary group that focuses on placental research and that is embedded in the Department of PDN; see http://www.trophoblast.cam.ac.uk/. You should have considerable experience in a range of standard molecular biological techniques, and of working with breeding colonies of mice. You should be able to work autonomously as well as part of a team, and show considerable resourcefulness and initiative. Your interpersonal skills must enable you to communicate effectively with staff and students at all levels.

Candidates should have an HNC or equivalent in a biological subject with several years of relevant experience and either be, or able to become, a Home Office Licence holder. As well as overseeing the day-to-day running of the lab and the induction of new members, you will input into the design, development and modification of new experimental protocols and techniques. In particular, you will be responsible for maintaining high-resolution ultrasound imaging equipment and performing scans on laboratory rodents (training will be provided as necessary).

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a security check.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for applications is midnight on Thursday 11 June 2015.

Please quote reference PM05987 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate: Neuroanatomy/Molecular Biology (Fixed Term)

From Jobs at the University of Cambridge. Published on May 18, 2015.

Studying the molecular pathogenesis and consequences of neurodegeneration in Huntington's disease using transgenic mouse models

A neuroanatomist/molecular biologist position is available in Prof. Jenny Morton's research group at the University of Cambridge (UK), to work on a project aimed at understanding the neuronal dysfunction in Huntington's disease (HD). HD is an incurable neurodegenerative genetic disorder that causes progressive deterioration of motion and cognitive function, as well as changes in psychiatric domains such as anxiety and depression. The successful applicant will join an interdisciplinary team assessing the effects of neurodegeneration in HD on cognition, circadian rhythms, sleep and metabolism in transgenic mouse models of HD. Our aim is to find treatments that will slow down or halt the disease progression.

Applicants must have experience in in situ hybridisation, immunohistochemistry, bright field and fluorescent microscopy and RT-PCR. The ideal applicant will also have familiarity with mouse models of neurodegenerative disease.

Applicants should have, or be close to finishing, a PhD degree (or equivalent), preferably with a background in Neuroscience.

The successful applicant will be a careful and methodical worker who is self-motivated and able to conduct experiments and analyse data independently. Careful observation skills and accurate record keeping are essential.

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please remember to upload your CV and a covering letter outlining your suitability for the post.

The closing date for applications is midnight on Thursday 18 June 2015.

Please quote reference PM06124 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Koo Lab) x 2 (Fixed Term)

From Jobs at the University of Cambridge. Published on May 18, 2015.

Fixed-term: The funds for this post are available for 2 years in the first instance.

The Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute is an international centre of excellence for stem cell research and regenerative medicine. Scientists in the Institute collaborate to advance our knowledge of various stem cell types and to perform pioneering work in translational research areas, providing the foundation for new medical treatments.

We are looking for a self-motivated, reliable and well-trained post-doctoral researchers to join the research team of Dr. Bon-Kyoung Koo. His team will investigate a novel quiescent Troy+ epithelial stem cell population in the stomach. Upon tissue damage, Troy+ stem cells actively divide to regenerate lost cell types. The discovery of Troy+ stomach stem cells enables us to investigate how an adult tissue can retain its homeostasis after various types of injury. This study will help us understanding how homeostasis is achieved in the adult stomach and in other tissues, which will potentially lead to the development of successful adult stem cell therapy. We will combine confocal analysis of near naïve stomach sections and whole mounts, mathematical modelling, gene expression and epigenetic analysis with mouse genetics to investigate the contribution of Troy+ quiescent stem cells in homeostasis and injury repair, one of the most intriguing processes in adult stem cell biology.

His team also focuses on the role of E3 ubiquitin ligases (E3s) in regulating responsiveness of stomach stem cells to instructive signals. The adult stomach stem cells can be cultured in vitro in the form of organoids, which provide a unique mammalian genetic model system in vitro. Advanced mouse genetics, 3D organoid culture and diverse cellular and biochemical approaches will be combined to explore the role of E3s in the homeostatic regulation of stomach epithelia.

Homepage: http://www.stemcells.cam.ac.uk/researchers/principal-investigators/bon-kyoung-koo

Requirements:

Post I

A PhD degree. At least one publication with 1st authorship in a high impact journal. Strong background in biochemistry and molecular biology. Strong background in cell biology such as E3-DUB, Cell cycle, time lapse cell imaging. Strong background in signalling pathway analysis and experience with genetic models. Experience in MS analysis, microarray, protein purification, lentivirus, fluorescence imaging, and FACS is preferred, but not essential. A proven capacity to design, execute and correctly interpret your own experiments. Good communication skills in English. Highly independent, motivated, ambitious, and collaborative person.

Post II

A PhD degree. At least one publication with 1st authorship in a high impact journal. Strong background in mathematical modelling and simulation to address systems-level questions in biology. Strong background in high-throughput data analysis for systems biology approach. Good programming skill in MATLAB or R. Experience in wet experimental techniques such as animal cell culture, western blot, molecular cloning and Q-RT-PCR is desirable, but not essential. A proven capacity to design, execute and correctly interpret your own experiments. Good communication skills in English. Highly independent, motivated, ambitious, and collaborative person.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is Thursday 18th June 2015.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Informal enquiries about the post are also welcome via email on cscrjobs@cscr.cam.ac.uk.

Interviews will be held in July 2015. If you have not been invited for interview by 31st July 2015, you have not been successful on this occasion.

Please quote reference PS06117 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on May 15, 2015.

Applications are invited for a postdoctoral research associate position in Dr Juan Mata's laboratory in the Department of Biochemistry, University of Cambridge, Central Cambridge to work on the following BBSRC-funded project: 'Role of RNA-binding proteins in the control of RNA turnover: a genome-wide approach'. The project will use fission yeast as a model system to study how RNA decay is coordinated at the level of the whole cell, and will involve functional genomics approaches, biochemical methods and bioinformatics. More information on the laboratory can be found at http://www.bioc.cam.ac.uk/uto/mata.html.

Applicants should hold or have recently submitted for a PhD in a relevant subject, such as Genetics, Molecular Biology or Biochemistry. Direct experience with fission yeast or high throughput methods such as RNA-seq would be an advantage, but is not absolutely required. Funding will be available from 1st September 2015 for up to 9 months.

Fixed-term: The funds for this post are available for up to 9 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For informal enquiries please email Juan Mata - jm593@cam.ac.uk.

Please quote reference PH06104 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

PhD position in Cardiovascular Toxicity (Fixed Term)

From Jobs at the University of Cambridge. Published on May 15, 2015.

Applications are invited for a fully-funded PhD position for Home (UK)/EU students in the Department of Pharmacology at the University of Cambridge. The studentship is fully funded by AstraZeneca and will be based within the Department of Pharmacology, which offers comprehensive facilities for research in a modern building located in the centre of Cambridge http://www.phar.cam.ac.uk. The student will also have access to state-of-the-art facilities at AstraZeneca laboratories in Cambridge.

Project Information

A new drug must be effective but also safe. Cardiovascular toxicities associated with drugs, including vascular damage, thrombosis and heart failure, are a major reason for drugs to be withdrawn from development or after approval. A further important challenge is to predict the risk of cardiovascular toxicity in patients with an already higher risk of cardiovascular disease, such as diabetic patients. Therefore, there is a pressing need for new models that accurately predict human vascular injury in healthy and at-risk patients.

In this project we will use human blood vessels in a new ex vivo model of drug-induced vascular damage and thrombo-inflammation. We will use high-resolution imaging and biomarker analysis to investigate how drugs influence vessel reactivity, inflammation and thrombosis in healthy and diseased blood vessels. In this way we will provide new mechanistic insights into how drugs cause blood vessel damage.

Applicants must have, or should expect to gain, a minimum of a 2.1, or equivalent, in pharmacology (or a related subject such as biochemistry, physiology or cellular and molecular biology). UK students who meet the UK residency requirements will be eligible for a full studentship (stipend currently £17,000 p.a.). EU students will also be eligible for a full studentship.

Further information can be obtained from Dr. Matthew Harper (mth29@cam.ac.uk, http://www.phar.cam.ac.uk/research/harper/Summary).

Applications should be made on-line via the Cambridge Graduate Admissions Office before the deadline: http://www.admin.cam.ac.uk/students/gradadmissions/prospec/apply/- with Dr Matthew Harper identified as the supervisor.

Please quote reference PL06111 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

Project Manager - Pluripotent Stem Cell Platform

From Jobs at the University of Cambridge. Published on May 14, 2015.

Limited funding: The funds for this post are available until 31 January 2018 in the first instance.

Three UK Research Councils; Biotechnology and Biological Sciences Research Council, Engineering and Physical Sciences Research Council and the Medical Research Council have invested £25m in research and equipment to develop the UK Regenerative Medicine Platform (UKRMP www.ukrmp.org.uk). The Pluripotent Stem Cell Platform (PSCP) is one of five UKRMP Hubs formed to tackle critical challenges in developing regenerative treatments from laboratory discoveries. PSCP brings together researchers from several institutions to develop the processes for taking pluripotent stem cells and their derivatives from laboratory research to the manufacture of safe, consistent and effective products suitable for clinical applications.

PSCP now has an exciting opportunity for a Project Manager with experience in management and administration at the interface between academia and industry.

We are looking for a proactive and motivated individual to manage the PSCP portfolio according to industry best practice; determining and delivering to agreed scope, quality, budget and deadlines. The Project Manager will manage a number of projects concurrently and will maintain accurate project plans, work schedules, issue and risk logs to enable projects to be delivered successfully. You will coordinate regular meetings at the different partner sites. You will develop summary documents and reports, will organise meetings and will lead the daily administration of the project. You will be a confident and articulate communicator who delivers information concisely and effectively. You will have the experience and interpersonal skills to build effective relationships with funders and a range of stakeholders including industry and regulators.

Experience of finance management, budgeting, and administration in a research-led environment is essential. Experience of leading, or working as part of, a management team with accountability for group and individual performance is highly desirable.

You will be educated to at least degree level and have a further qualification (MSc, PhD or MBA).

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is Sunday 14th June 2015.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Informal enquiries about the post are also welcome via email on cscrjobs@cscr.cam.ac.uk.

Interviews will be held on the afternoon of Wednesday 1st July 2015. If you have not been invited for interview by 24th June 2015, you have not been successful on this occasion.

Please quote reference PS05620 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate x 2 (Fixed Term)

From Jobs at the University of Cambridge. Published on May 13, 2015.

Applications are invited for 2 Research Associate positions starting from August 2015.

The successful candidates will join Professor Ian Goodfellow's research group and investigate the molecular basis of RNA virus virulence and the generation of control measures. Post 1 is funded to 30/09/2017 and will focus on the study of norovirus-host interactions using state of the art approaches to understand norovirus pathogenesis and to develop novel therapeutic approaches. Post 2 is funded to 31/03/2017 and will focus on the analysis of Ebola virus genetic diversity, evolution and pathogenic mechanisms during the ongoing epidemic in Sierra Leone. This post may also involve a significant amount of fieldwork based in Sierra Leone.

Ideally the applicants should have a PhD and a strong background in virology. Relevant experience in molecular virology is essential. The post-holders should be highly motivated, and have the ability to plan and conduct high quality experimental work within a multidisciplinary team. They must also be willing to work independently in challenging environments.

The ability to work both as part of a team, and independently, coupled with excellent communication, organizational and problem solving skills are required. The duties/responsibilities of this post include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures as outlined on the Further Information Document.

Interviews will take place in Cambridge on the 18th and 19th of June. For further information contact Prof. Ian Goodfellow (ig299@cam.ac.uk)

Where the successful applicant does not yet have a PhD, he/she will normally be under-appointed as a Research Assistant in a Research Associate post (on the understanding that he/she will be appointed as a Research Associate upon successful completion of his/her PhD). The higher Research Associate salary should be backdated to the submission date of their thesis.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should provide a CV, the filename of which should be "CV-followed by your name", including contact details of two or more referees, and a covering letter addressing the selection criteria and noting which post you are applying for (Post 1 or Post 2). Any queries regarding this position should be directed to jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK06097 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on May 13, 2015.

A position is open for a postdoctoral research associate based at the OpenPlant Laboratory in Cambridge, based in the Department of Plant Sciences at the University of Cambridge, and directed by Dr. Jim Haseloff.

The appointee will develop a research project based on the development of new synthetic biology tools for engineering the plastid genome in the model plant Marchantia polymorpha. Work with Marchantia allows streamlined approaches to genome modification, secondary metabolism and morphogenetic engineering. We are looking for a highly motivated post-doctoral scientist to work in this area.

The successful candidate will have a strong background in plant molecular biology or synthetic biology. Candidates must have or be close to finishing a PhD in a relevant biological discipline. Experience with synthetic biology, plant molecular biology and advanced microscopy will be advantageous.

OpenPlant is a BBSRC-EPSRC funded Synthetic Biology Research Centre. It is based in the United Kingdom and is a collaboration between the University of Cambridge and the John Innes Centre and The Sainsbury Laboratory, Norwich. The OpenPlant SBRC is focused on the development of open foundational technologies for plant synthetic biology and their application for engineering new traits in crop systems. OpenPlant will (i) fund interdisciplinary efforts in plant Synthetic Biology, to explore novel foundational technologies and applications, build shared resources and provide a point of exchange for young scientists and entrepreneurs; (ii) promote two-tier intellectual property models that will promote sharing of DNA components and freedom-to-operate for commercial applications of plant synthetic biology, and (iii) address responsible innovation, and explore the potential wider impacts of synthetic biology on sustainable practices in agriculture, bioproduction, land use and environmental conservation. (http://www.openplant.org)

Please note that applicants who do not hold a PhD will be appointed at the lower level of Research Assistant.

Fixed-term: The funds for this post are available for 30 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For further information contact Dr Jim Haseloff (jh295@cam.ac.uk)

Please quote reference PD06099 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate & Laboratory Manager (Fixed Term)

From Jobs at the University of Cambridge. Published on May 12, 2015.

An exciting position for a postdoctoral research associate to help manage the OpenPlant laboratory at the Department of Plant Sciences, University of Cambridge has become available.

The Cambridge OpenPlant Laboratory is directed by Dr. Jim Haseloff. Work will focus on the development of foundational technologies for engineering of the model plant Marchantia polymorpha. The newly renovated laboratory will house state of the art equipment for automated DNA assembly, genome editing, plant transformation, cytometry and high throughput microscopy. As well as research activities, the appointee will help manage the laboratory, including supervision of a research technician and training and oversight of maintenance of instrumentation.

The successful candidate will have a strong background in plant molecular biology or synthetic biology, including a PhD in a relevant area. Experience with synthetic biology techniques, DNA assembly, cytometry, microscopy and laboratory management will be advantageous.

OpenPlant is a BBSRC-EPSRC funded Synthetic Biology Research Centre. It is based in the United Kingdom and is a collaboration between the University of Cambridge and the John Innes Centre and The Sainsbury Laboratory, Norwich. The OpenPlant SBRC is focused on the development of open foundational technologies for plant synthetic biology and their application for engineering new traits in crop systems. OpenPlant will (i) fund interdisciplinary efforts in plant Synthetic Biology, to explore novel foundational technologies and applications, build shared resources and provide a point of exchange for young scientists and entrepreneurs; (ii) promote two-tier intellectual property models that will promote sharing of DNA components and freedom-to-operate for commercial applications of plant synthetic biology, and (iii) address responsible innovation, and explore the potential wider impacts of synthetic biology on sustainable practices in agriculture, bioproduction, land use and environmental conservation. (http://www.openplant.org)

Fixed-term: The funds for this post are available until 2 September 2019 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should upload a CV and a covering letter addressing the selection criteria. For further information contact Dr Jim Haseloff (jh295@cam.ac.uk)

Please quote reference PD06087 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Qualified and Listed Veterinary Nurse - Research Nurse - Small Animal Surgery (Fixed Term)

From Jobs at the University of Cambridge. Published on May 12, 2015.

University of Cambridge Department of Veterinary Medicine West Cambridge Site

Limit of Tenure: 1 year in the first instance

Applications are invited for a research nurse position within the Surgical Discovery Centre (SDC). The focus of the position will be to support the development of a vibrant and sustainable clinical research program within the Small Animal Surgery service at Queen's Veterinary School Hospital. The research activities will be coordinated from the newly established SDC, led by Professor Matthew Allen. The clinical research will initially focus on musculoskeletal diseases and disorders, but is expected to expand to include soft tissue and other surgical sub-specialties.

Applicants should be qualified and listed nurses, with an interest in all aspects of nursing and surgery and significant clinical experience in either primary or referral practice. It is desirable for applicants to hold a Diploma in Advanced Veterinary Nursing. The successful applicant must be competent in clinical record keeping, as well as in the use of Microsoft Office applications including Word and Excel. Applicants should be able to demonstrate excellent client communication, a professional demeanour and have the ability to work well within a team. Familiarity and practical experience in an operating theatre setting would be highly desirable, as would prior participation in clinical trials activities in small animals.

Informal enquiries should be directed to Professor Matthew Allen (mja1000@cam.ac.uk).

Further information about the role: click on link below

Closing date 31 May 2015

Interviews will be held on: 11th June 2015

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not done so already) and log in before completing the online application form.

Please quote reference PP06093 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate x 2 (Fixed Term)

From Jobs at the University of Cambridge. Published on May 12, 2015.

Two Wellcome Trust funded positions are available to work with Dr Andrew Welchman at the University of Cambridge. The successful applicant will combine brain imaging methods (fMRI, TMS), computational analysis, psychophysical measurements and modelling to examine the neural basis of 3-D perception. The work makes use of state-of-the-art brain imaging techniques and analysis methods.

Research will be conducted within well-equipped labs that incorporate a range of bespoke equipment. The Department of Psychology provides an excellent working environment with a pronounced research focus and international expertise in Vision Science, Behavioural, Sensory and Cognitive Neuroscience. Dr Welchman's research group further benefits from regular interactions with a wide network of international collaborators.

Candidates should hold or expect to hold a Ph.D. in Experimental Psychology, Neuroscience, Computer Science, Physics, Mathematics or a related field. Programming skills (e.g. Matlab, C) are essential and experience with brain imaging methods (fMRI, EEG, TMS) is desirable.

Further information may be downloaded below.

Informal enquiries should be directed to Dr Andrew Welchman (http://www.andrewwelchman.info)

Fixed-term: The funds for this post are available for 12 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Please quote reference PJ06084 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant[Temporary Cover] (Maternity Cover)

From Jobs at the University of Cambridge. Published on May 11, 2015.

Applicants are invited for a Research Assistant position working in the laboratory of Dr Marko Hyvonen in the University of Cambridge, Department of Biochemistry, Central Cambridge. The post holder will support the research in the Hyvonen group both in the general laboratory management (ordering, stock keeping) and by assisting postdoctoral fellows in their research projects.

A successful applicant is expected to have previous experience in modern molecular biology techniques, including DNA cloning, microbiology, protein expression and/or protein purification. Experience in laboratory management is desired. The applicant is expected to be have good interpersonal skills, to be helpful and collaborative in research group environment and to be able to work carefully and independently towards set goals in a timely manner.

The successful candidate will be educated to first degree level.

Maternity cover: This post is fixed-term for 6 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries can be addressed to Dr Hyvonen by email - mh256@cam.ac.uk

Please quote reference PH06066 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Bioinformatician/Computational Biologist)

From Jobs at the University of Cambridge. Published on May 11, 2015.

Applications are invited for a Postdoctoral Research Associate in the laboratory of Professor Azim Surani. We are investigating the mechanism of mammalian germline, early development and stem cell biology. The work includes genome-wide analysis of high throughput sequencing data of transcriptional networks regulating cell fate decisions, regulatory elements and epigenetic programming (chromatin modifications, DNA methylation) in response to environmental and signalling cues. We are working on mouse and human, amongst other organisms, to gain comprehensive insights on underlying mechanisms. We also use single cell analysis. Expertise in the analysis of next-generation sequencing data and related statistical methods is essential. Previous experience in modeling regulatory networks and epigenetic states and willingness to become familiar with the biological systems under investigation is an advantage. Applicants should have a PhD in a relevant subject. The group is based at the renowned Gurdon Institute at the University in the centre of Cambridge. Please contact Azim Surani for informal enquires (a.surani@gurdon.cam.ac.uk)

Limited funding: The funds for this post are available for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PR06075 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Laboratory Research Technician (Fixed Term)

From Jobs at the University of Cambridge. Published on May 11, 2015.

The Department of Plant Sciences are looking for a technician to provide support for the OpenPlant Laboratory in Cambridge. Work there will focus on the development of foundational technologies for engineering of the model plant Marchantia polymorpha. The newly renovated laboratory will house state of the art equipment for automated DNA assembly, genome editing, plant transformation, cytometry and high throughput microscopy. The appointee will provide technical support for plant transformation and culture work, microbiological and molecular biology experiments, as well as general laboratory support work.

The successful candidate will have a background in molecular biology or synthetic biology, and demonstrate an ability to work independently. Applicants should be educated to HNC level in a biological subject. Experience with synthetic biology techniques, DNA assembly, cytometry, microscopy and laboratory management will be advantageous.

OpenPlant is a BBSRC-EPSRC funded Synthetic Biology Research Centre. It is based in the United Kingdom and is a collaboration between the University of Cambridge and the John Innes Centre and The Sainsbury Laboratory, Norwich. The OpenPlant SBRC is focused on the development of open foundational technologies for plant synthetic biology and their application for engineering new traits in crop systems. OpenPlant will (i) fund interdisciplinary efforts in plant Synthetic Biology, to explore novel foundational technologies and applications, build shared resources and provide a point of exchange for young scientists and entrepreneurs; (ii) promote two-tier intellectual property models that will promote sharing of DNA components and freedom-to-operate for commercial applications of plant synthetic biology, and (iii) address responsible innovation, and explore the potential wider impacts of synthetic biology on sustainable practices in agriculture, bioproduction, land use and environmental conservation. (http://www.openplant.org)

Fixed-term: The funds for this post are available until 2 September 2019 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For further information contact Dr Jim Haseloff (jh295@cam.ac.uk)

Please quote reference PD04872 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Human Anatomy Technical Co-ordinator

From Jobs at the University of Cambridge. Published on May 11, 2015.

Applications are invited for the post of Human Anatomy Technical Co-ordinator to manage the Human Anatomy Dissection facility, support the undergraduate teaching programme in topographical anatomy (see www.pdn.cam.ac.uk/teaching/anatomy/index.shtml) and ensure compliance with the Human Tissue Act and best health and safety practice. You will support the management of the body donation programme, undertake teaching administration, maintain responsibility for health and safety in the Human Dissection Room, supervise four members of Assistant Staff and act as a budget holder for the facility.

The successful candidate should have a BSc or equivalent in a biological subject, have extensive experience of running a biological laboratory and have good understanding of health and safety management in a laboratory setting. You will have good IT and organisational skills and considerable supervisory experience. The ability to communicate sensitively with a range of individuals is essential as are the capacity to pay meticulous attention to detail and to problem solve. A qualification in human anatomy would be advantageous.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a security check.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please complete the online application as fully as possible.

For informal enquiries, please contact Dr Cecilia Brassett (cb457@cam.ac.uk) or Dr Helen Taylor (hlt37@cam.ac.uk).

Please quote reference PM06074 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Laboratory Technician (Fixed Term)

From Jobs at the University of Cambridge. Published on May 11, 2015.

Applications are invited for the position of Laboratory Technician in the research group of Dr Braybrook, which focuses on plant biomechanics and development (www.plantmechanome.org). The group provides a dynamic and enjoyable working environment. This is a key role within the research team which requires a motivated, dynamic and flexible individual.

The post holder will be involved in research through organisation and execution of own research, maintenance of the research environment, facilitating others' research in a team environment, transfer of skills and training of new members, and collation of results and development of testing methods.

The successful applicant will be a strong team player, highly solution oriented, and self-motivated. Excellent interpersonal and organisational skills are essential, alongside the ability to work with a high degree of accuracy, including outstanding record keeping. Candidates must have good IT literacy, a willingness and ability to learn new methodologies and strong communication skills, including demonstrable ability to write clearly and concisely in English. Applicants are strongly encouraged to read the further particulars for the role when stating their suitability for the position.

Experience in any of the following is advantageous: RNA work, quantitative PCR, gene cloning, histology, confocal microscopy and plant growth.

Candidates must have an educational minimum at the HNC level, or equivalent demonstrated experience in at least one area of core importance to the research group, such as plant development, molecular biology, plant genetics, biological imaging, or engineering arising from either work experience in a high level research environment or a period of postgraduate training. Ideally a degree at any level in biology is advantageous.

Information about the Sainsbury Laboratory and further particulars for the role can be found at: http://www.slcu.cam.ac.uk/

The post is full-time and available immediately.

Fixed-term: The funds for this post are available until 31 October 2016 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please also send a copy of your CV and a motivation letter to: enquiries@slcu.cam.ac.uk

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within two weeks of the closing date, please consider your application as unsuccessful on this occasion.

Please quote reference PT06082 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Pluripotent Stem Cell Platform Research Associate x 2 (Fixed Term)

From Jobs at the University of Cambridge. Published on May 11, 2015.

Fixed-term: The funds for this post are available until 31 January 2018 in the first instance.

The Pluripotent Stem Cell Platform (PSCP) is a hub in the UK Regenerative Medicine Platform, a joint research council programme to tackle the critical challenges in developing new regenerative treatments (www.ukrmp.org.uk). PSCP is a multi-disciplinary collaboration focussed on the quality controlled manufacturing and differentiation of human pluripotent stem cells suitable for clinical applications (http://www.ukrmp.org.uk/hubs/cell-behaviour-differentiation-and-manufacturing/).

Two post-doctoral positions are available as part of the PSCP for projects based in Cambridge under the direction of Ludovic Vallier, Roger Barker and Austin Smith at the Wellcome Trust-MRC Stem Cell Institute (www.stemcells.cam).

The research is centred on optimising the generation from human embryonic and induced pluripotent stem cells of neural derivatives suitable for development of cell based therapies, in particular midbrain dopaminergic neurons for Parkinson's disease.

Candidates should have a PhD with experience in the culture and analysis of pluripotent stem cells or neural stem cells and/or neuronal differentiation and functional characterisation.

Post 1: Generation, expansion, characterisation and differentiation of neural progenitors

Post 2: Differentiation, characterisation and evaluation in pre-clinical models of mesencephalic dopamine neurons

Applications are encouraged from candidates with experience of work in this area and an appreciation of cell production for clinical use and trials.

Technical support is available and access to a range of flow cytometry, imaging and qPCR instrumentation.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is the Thursday 11th June 2015.

Please upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Informal enquiries about the post are also welcome via email on cscrjobs@cscr.cam.ac.uk.

Interviews will be held on the afternoon of Tuesday 30th June 2015. If you have not been invited for interview by Thursday 25th June 2015, you have not been successful on this occasion.

Please quote reference PS06068 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate - Plant Biotechnology in Liverworts (Fixed Term)

From Jobs at the University of Cambridge. Published on May 08, 2015.

Applications are invited for a Post-doctoral Research Associate position in the group of Dr Sebastian Schornack at the Sainsbury Laboratory (SLCU), Cambridge University, to develop tools for manipulation of early descendant land plants.

The position is part of the OpenPlant (http://openplant.org/) project. OpenPlant is a BBSRC-EPSRC funded Synthetic Biology Research Centre. It is based in the United Kingdom and is a collaboration between the University of Cambridge, the John Innes Centre and The Sainsbury Laboratory Norwich. The successful candidate will benefit from engagement with laboratories in all partner organisations.

The successful candidate will develop new molecular biological and genetic resources (in particular TAL effector activators and repressors) to modulate gene expression in early descendant plants (e.g. Liverworts/hornworts) or to achieve genome editing (TALENs). Main model organisms will be the Agrobacterium-transformable liverwort Marchantia polymorpha and related species.

Along our group's general interest in understanding principles of plant colonisation by filamentous microbes, the candidate will have the opportunity to explore projects involving beneficial and/or detrimental plant microbe interactions with liverworts and hornworts. The candidate will be provided with horticultural/technician support and will be able to team up with post docs studying plant-microbe interactions in angiosperms.

Candidates must have or be close to finishing a PhD in a relevant discipline (e.g. plant biology, plant biotechnology). Knowledge of modular cloning strategies such as GoldenGate cloning is essential. Previous experience with synthetic biology or genome editing tools such as TAL effectors as well as handling of sterile plants, Agrobacterium-mediated plant transformation or knowledge on plant-microbe interactions is desirable. Proficiency in sequence analysis, general biological databases, qPCR analysis and confocal fluorescence microscopy is also required.

The successful candidate will be fully involved in the basic research in these areas whilst also writing up their research work for presentation and publication. The post holder may be required to assist in the supervision of student projects, provide instructions to students and deliver seminars relating to their research area.

Good communication skills are essential as the post holder will need to work well in a team and collaborate with other researchers in the Institute. Candidates would ideally have published or submitted papers in this area. Candidates should demonstrate a history of science communication (e.g. presentations, outreach activities, teaching).

Information about the Sainsbury Laboratory and the generic further particulars for the role can be found at http://www.slcu.cam.ac.uk/

Fixed-term: The funds for this post are available for 2.5 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload a copy of your full CV, a supporting statement and contact information of three referees.

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within three weeks of the closing date, please consider your application as unsuccessful on this occasion.

Please quote reference PT06067 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Chief Aquatics Technician

From Jobs at the University of Cambridge. Published on May 07, 2015.

We are looking for someone to oversee the day-to-day running of a state-of-the-art aquatic facility. The role involves the husbandry, maintenance and care of the fish colony, looking after the plant, supervision of two staff and regular liaison with research staff from different departments. You will assist the lead NACWO in all Home Office reporting and compliance issues.

The successful candidate will work with a high degree of autonomy to ensure that all facility and record keeping duties are met and that high a level of service is provided to researchers.

You should have the Institute of Animal Technology Membership Diploma or Level 4 or an equivalent qualification and/or experience, plus considerable work experience in a relevant role. You should also be familiar with record-keeping databases, be a good communicator and have, or be able to obtain, a Home Office personal licence.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and security check.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please complete the online application as fully as possible.

Please quote reference PM06051 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

MRC ITTP PhD Studentship (Fixed Term)

From Jobs at the University of Cambridge. Published on May 06, 2015.

Molecular mechanisms of bile salt export pump (BSEP) inhibition in drug-induced liver injury

An exciting opportunity has arisen for a PhD student to work on a project funded by the MRC Integrative Toxicology Training Partnership (ITTP) in the research group led by Dr Hendrik W. van Veen at the Department of Pharmacology, University of Cambridge. More information about the research group is available at http://www.phar.cam.ac.uk/research/vanveen.

Bile acids are synthesized within hepatocytes and excreted into bile by ATP-dependent active transport proteins located in the apical plasma membrane, most notably the Bile Salt Export Pump (BSEP, ABCB11). Impaired BSEP activity results in accumulation of bile acids within hepatocytes, which can cause cholestatic liver injury. Our understanding of the molecular mechanisms of BSEP inhibition is still very limited.

The PhD project will aim to study molecular mechanisms of BSEP inhibition in more detail. This knowledge will aid in the design of molecules that are unlikely to inhibit BSEP, and thereby inform and guide in vitro testing strategies, as well as molecules that can stimulate BSEP activity in the treatment of cholestatic disorders.

The project will use molecular modelling as a basis for mutational analyses, aiming to reconstitute purified wild-type and mutant proteins in proteoliposomes, and to characterize these proteins through measurements of substrate transport and binding. This research will be in collaboration with Dr Dominic Williams within the Translational Safety Department of AstraZeneca in Cambridge, where part of the research activities will be carried out.

Applicants should have or shortly expect to obtain a minimum of a UK II.i Honours Degree (or equivalent) in Pharmacology or a related subject including Cellular or Molecular Biology and Biochemistry. Competition is intense and successful applicants are likely to demonstrate high academic achievements. We are looking for a highly motivated, enthusiastic individual, capable of thinking and working independently, with an interest in, and possibly some knowledge of, molecular modelling and the purification and reconstitution of membrane proteins.

Eligibility: In accordance with the MRC Studentship guidelines and residents requirements, to be eligible for a full award, a student must have: Settled status in the UK, meaning they have no restrictions on how long they can stay and been "ordinarily resident" in the UK for 3 years prior to the start of the studentship. This means they must have been normally residing in the UK (apart from temporary or occasional absences) and not been residing in the UK wholly or mainly for the purpose of full-time education. This does not apply to UK or EU Nationals.

Funding: Full funding covering the University Composition Fee, Maintenance (currently £14,057 pa), an allowance for conference attendance and consumables is provided for up to 4 years, with effect from 1 October 2015.

Informal enquiries about the position can be made to Dr Hendrik W. van Veen (hwv20@cam.ac.uk).

To apply, please e-mail the following at phar-gradadmissions@lists.cam.ac.uk:

1) your CV with full contact details of 2 academic referees (max two A4 pages), 2) your academic transcript, and 3) a cover letter (max two A4 pages) highlighting (a) your background/research interests, (b) how you will fit in with this project, (c) what you hope to achieve in the programme and your career aspirations beyond the programme, and (d) why this programme at the Department of Pharmacology, University of Cambridge is the best place for you to pursue your interests.

Applications will be assessed as and when they are submitted. Face-to-face and/or telephone interviews will take place up to 24 June 2015.

Please quote reference PL06039 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on May 06, 2015.

Applications are invited for a Research Assistant/Associate to work in the group of Dr. Milka Sarris in the Department of Physiology, Development and Neuroscience at the University of Cambridge (http://www.pdn.cam.ac.uk/staff/sarris/index.shtml). The post is funded by an MRC project investigating how leukocytes are guided to sites of infection and inflammation in a zebrafish model.

Candidates should have a PhD, or be working towards a PhD, in Cell Biology or a related field. Experience with molecular and cell biology techniques is essential. Experience with microscopy, image analysis and zebrafish manipulation would be an advantage. We are looking for an enthusiastic and self-motivated researcher with a strong interest in the area of cell signaling and cell migration.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

For informal enquiries please e-mail Dr. Sarris at: ms543@cam.ac.uk

The closing date for applications is midnight on Monday 15 June 2015.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Please quote reference PM06037 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Post-doctoral Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on May 01, 2015.

Post-doctoral Research Associate in Microbiology

A Post-doctoral Research Associate position is available to work on regulation of the glyoxylate shunt in the opportunistic human pathogen, Pseudomonas aeruginosa. The post is based in University of Cambridge, Department of Biochemistry, Central Cambridge working in the laboratory of Dr Martin Welch, and is funded by the BBSRC.

The successful applicant will ideally have experience in protein chemistry, enzymology and molecular microbiology. In addition experience in 13C flux analysis and a working knowledge of Python programming are desirable but not essential, as training will be provided if necessary.

The successful applicant will investigate the enzymology (kinetic/structural properties and regulation) of the TCA cycle/glyoxylate shunt branchpoint in P. aeruginosa. The enzymology of this metabolic branchpoint differs significantly from that in the well-characterized organism, Escherichia coli. Moreover, recent work has shown that flux through the glyoxylate shunt controls the activity of the major virulence determinant in P. aeruginosa; the Type III Secretion (T3S) System. In collaboration with colleagues in the United States, the accrued kinetic data will be used to populate a predictive flux model of the TCA cycle/glyoxylate shunt, with a view to identifying "nodes" that can be targeted to reduce flux through the shunt. Techniques include: microarray analyses and/or RNA-Seq, protein purification and characterization, kinetic analyses, [13C] flux analyses, protein phosphorylation ([32P]) assays, biophysical analyses, Westerns, in silico modelling and virulence assays (T3S).

The ideal candidate will have a PhD or has recently submitted for a PhD in a relevant science.

Interviews are anticipated during June.

Fixed-term: The funds for this post are available for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made to Martin Welch - mw240@cam.ac.uk

Please quote reference PH06006 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate in Mass Spectrometry (Fixed Term)

From Jobs at the University of Cambridge. Published on May 01, 2015.

Postdoctoral Research Associate position in lipidomics and metabolomics

A postdoctoral research associate position is available for up to three years (12 months in the first instance) to work in the laboratory of Dr J.L. Griffin, University of Cambridge, Department of Biochemistry, Tennis Court Road, Central Cambridge. The project will develop tools to measure lipid species in conjunction with ion mobility, an exciting development in mass spectrometry which will allow the separation of ions according to their cross sectional area as well as their mass to charge ratio. As an experienced mass spectrometrist involved in method development, you will be expected to work alongside a bioinformatician who will develop new software tools for processing the data obtained.

We are looking for an experienced mass spectrometrist, ideally with some background in metabolomics and/or lipidomics. The work is a collaborative project between Dr. J.L Griffin (Dept of Biochemistry), Prof. Michael Wakelam (Babraham Institute) and Agilent technology. As part of this project the successful candidate will have access to a state of the art ion mobility Q-ToF LC-MS to develop new tools for lipidomics, and building on our work in diabetes and metabolic diseases (Griffin) and cancer (Wakelam) use the instrument to explore cellular signalling in these disease processes. Some examples of this work can be found in Roberts LD et al., Lancet Endocrinology, 2014; Roberts LD et al., Methods in Enzymology, 2014; Zhang Q & Wakelam MJ, Adv Biol Regul 2014.

Skills required in mass spectrometry and a general interest in metabolism and disease processes in mammals. Previous work in metabolomics and/or lipidomics would be an advantage.

Applicants should have a PhD or the equivalent in a relevant science.

Fixed-term: The funds for this post are available for 12 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made to Dr J.L Griffin - jules.griffin@mrc-hnr.cam.ac.uk

Please quote reference PH06004 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant / Associate - Drosophila genetic data curator

From Jobs at the University of Cambridge. Published on May 01, 2015.

FlyBase (http://flybase.org/) seeks a full-time biocurator to join the existing group at the University of Cambridge, UK (http://www.gen.cam.ac.uk/research/flybase.html). If you are looking for a fulfilling, fly-related career away from the bench, and enjoy the challenge of organizing complex data and presenting it clearly and concisely, then this is the job for you!

The primary responsibility of the FlyBase-Cambridge site is to identify genetic data from scientific articles concerning Drosophila and to record these data in a systematic manner. The data we capture include all genetic objects (genes, alleles, transgenic constructs, etc.) plus associated information such as phenotypes, genetic interactions, gene product functions and models of human disease. Curated data are subsequently integrated into the FlyBase database and made freely available via our website.

Established staff also: research strategies to improve data curation; work with other FlyBase sites to improve data display/querying on the website; interact with our user community by answering HelpMail and giving presentations/workshops at research conferences; have the opportunity to develop programming skills; contribute to FlyBase publications.

Essential skills/experience: a biological sciences degree and post-graduate research experience using Drosophila. You should be able to demonstrate the ability to identify and organize specified data and be able to work efficiently (i.e both quickly and accurately). You should also have good communication skills, including excellent written and spoken English and strong self-motivation as well as the ability to work in a team.

Useful skills/experience include: · familiarity with databases · familiarity with ontologies · programming · annotation/curation experience

Please note that applicants who do not hold a PhD will be appointed at the lower level of Research Assistant.

Interviews are anticipated to occur week commencing 8th June 2015.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries to Dr Steven Marygold (sjm41@gen.cam.ac.uk; Tel: +44(0)1223-333170).

Your application should include your CV and a covering letter, explaining why you are suited to the position.

Please quote reference PC06022 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate: Notch regulatory networks in development (Fixed Term)

From Jobs at the University of Cambridge. Published on Apr 30, 2015.

Applications are invited for a Research Associate post in Professor Sarah Bray's research group. You will work in a collaborative, multidisciplinary team investigating Notch regulatory networks in development and their relevance to disease. We are looking to recruit a highly motivated scientist with strong investigative skills. You should have a PhD in a relevant field with experience in molecular biology/genomic approaches, such as chromatin immunoprecipitation, in enhancer analysis and in Drosophila genetics. Further information about research in the Bray group can be found at: http://www.pdn.cam.ac.uk/staff/bray_s/index.shtml. For informal enquiries, please email Prof Bray at: sjb32@cam.ac.uk.

The post-holder will be located in central Cambridge.

Fixed-term: The funds for this post are available until 30 September 2016 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please quote reference PM06005 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate/Senior Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Apr 28, 2015.

Applications are invited for Senior/Research Associate post in fetal and placental physiology within the research group of Professor Abigail Fowden (http://www.pdn.cam.ac.uk/staff/fowden). You will be working on a range of projects investigating feto-placental development in response to environmental cues and their long term consequences. You will be able to develop your own research project within the constraints of the resources available. You will be expected to supervise third-year undergraduate laboratory projects, demonstrate in practical classes with an emphasis on reproductive biology and examine in reproductive biology courses.

The successful candidate should hold a PhD in a relevant area and have significant research experience in fetal and placental physiology, working with mice, rats and sheep. It is essential that you hold, or are able to obtain, a personal UK Home Office licence. You must be able to work independently and good teamwork and communication skills are expected. A willingness to give a small number of undergraduate lectures in the reproductive biology courses is desirable.

Consideration for the Senior Research Associate level role will be dependent upon sufficient depth of specialist knowledge in the disciplines, research methods and techniques listed above to develop research objectives, projects and proposals. Appointment as a Senior Research Associate is subject to the approval of the School of the Biological Sciences.

The post is available as full-time but applications for part-time working at the minimum of 80% would be considered.

Informal enquires regarding the position should be made to Professor Abby Fowden (alf1000@cam.ac.uk/+44 (0)1223 333855).

Fixed-term: The funds for this post are available until 31 July 2019 in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records) check.

Please quote reference PM05975 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Grants/Accounts Clerk

From Jobs at the University of Cambridge. Published on Apr 27, 2015.

The Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute has a full time Grants/Accounts Clerk vacancy.

The role is split between general accounting and grants administration under the supervision of the Senior Grant/Accounts Clerk in order to provide a full Grants/Accounts Service to the Institute staff.

We are looking for someone who has the ability to communicate at all levels and who can maintain a high level of accuracy whilst working to deadlines. The ability to work within and contribute to a team is essential. The Institute aims to provide this support in an efficient yet friendly manner whilst working closely as a team.

Candidates should be educated to GCSE level equivalent (including GCSE/O Level Mathematics and English), ideally with experience of working in a large organisation, excellent interpersonal and PC skills. A good understanding of transaction processes and financial systems would be an advantage.

If you feel you have the qualities that we are looking for and would like to work in this friendly Institute, we look forward to receiving your application.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for all applications is Wednesday 27th May 2015.

Informal enquiries about the post are also welcome via email on cscrjobs@cscr.cam.ac.uk.

Interviews will be held on Friday 12th June 2015. If you have not been invited for interview by 8th June 2015, you have not been successful on this occasion.

Please quote reference PS05969 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate - Plant Development and Cell Biology (Fixed Term)

From Jobs at the University of Cambridge. Published on Apr 24, 2015.

Applications are invited for a Post-doctoral Research Associate/Assistant position in the group of Dr Sebastian Schornack at the Sainsbury Laboratory (SLCU), Cambridge University, to study cell and developmental processes during the interaction of plants with filamentous microbes.

The overall aim of this position is to unravel effector-targeted plant processes with impact on plant development. Potential target processes include the actin/myosin network, exo/endocytosis and vesicle trafficking, cell division, cell wall biosynthesis and cell-cell communication.

The successful candidate will utilise model plant systems such as Nicotiana and Arabidopsis to develop independent lines of research by taking advantage of resources and unpublished data existing in the lab. The candidate will be provided with horticultural/technician support.

Candidates must have or be close to finishing a PhD in a relevant discipline (e.g. plant biology, plant biotechnology or related field). Previous plant cell biology or plant development experience in Nicotiana or Arabidopsis is essential. Proficiency in standard molecula cloning as well as fluorescent microscopy techniques is also required, alongside experience in plant cell transformation and computer-based sequence analysis. Experience in time-lapse microscopy, immunostaining, mutagenesis or cell sorting would be an advantage.

The successful candidate will be fully involved in the basic research whilst also writing up their research work for presentation and publication. The post holder may be required to assist in the supervision of student projects, provide instructions to students and deliver seminars relating to their research area.

Good communication skills are essential as the post holder will need to work well in a team and collaborate with other researchers in the Institute. Candidates would ideally have published or submitted papers in this area. Candidates should demonstrate a history of science communication (e.g. presentations, outreach activities, teaching).

Information about the Sainsbury Laboratory and the generic further particulars for the role can be found at: http://www.slcu.cam.ac.uk/

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload a copy of your full CV, a supporting statement including your areas of interest and contact information of three referees.

The Sainsbury Laboratory receives a high volume of applications. If you have not heard from us within three weeks of the closing date, please consider your application as unsuccessful on this occasion.

Please quote reference PT05957 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Independent Research Group Leaders in Cross-Disciplinary or Translational Stem Cell Science

From Jobs at the University of Cambridge. Published on Apr 24, 2015.

The Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute is founded on the concept that deep understanding of stem cell biology will contribute to transforming future healthcare (http://www.stemcells.cam.ac.uk)

The Institute has openings for Group Leaders who will complement and synergise with our existing programmes. In particular we are seeking investigators with expertise in two areas:

i. Bridging physical, materials or engineering sciences with stem cell biology

ii. Applying stem cell research to human disease

Junior group leader candidates will have a minimum of 3 years post-doctoral experience, distinctive research achievements, and an original project proposal. Senior group leader candidates will be internationally recognised for independent high quality science and have an exceptional and well-founded research proposal.

The Institute offers a collegiate environment with excellent core facilities plus extensive opportunities to pursue disease-oriented studies. Successful candidates will be supported to obtain external personal fellowship and grant support within 1-2 years. An interim start-up package is available. Depending on experience, you can expect remuneration between £38,511 - £65,453.

You can find the SCI Review 2014 on our website, at http://www.stemcells.cam.ac.uk/about-us/brochure/.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should upload a full curriculum vitae with contact details of 3 referees, and 1-2 page outline of research proposal, by Monday 1st June 2015.

Informal enquiries about the post are also welcome via email on cscrjobs@cscr.cam.ac.uk.

Interviews will be held on 28th and 29th July 2015.

Please quote reference PS05703 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant/Associate x 3

From Jobs at the University of Cambridge. Published on Apr 23, 2015.

The lab of Prof Tony Kouzarides is looking for 3 postdoctoral scientists to work on different aspects of research within the lab. The lab is in the Wellcome Trust/Cancer Research UK Gurdon Institute, a department of the University of Cambridge. Funding will initially be for a minimum of 3 years.

The first postdoc will work on Chromatin regulation in embryonic stem cells. In particular, the ideal candidate would have experience working with ES cells, an interest in miRNAs, and experience in CRISPR technology.

The second vacancy is for a postdoctoral scientist to work on epigenetic regulation in of lncRNAs in cancer. In particular the ideal candidate would have experience in enhancer RNAs and long non-coding RNAs in cancer, with a particular interest in p53 pathways.

The third vacancy involves a project on modifications of RNA. The ideal candidate would have a strong chemistry (or pure chemistry) background with a proficiency in biochemical approaches.

Candidates should have a PhD in Biological Sciences or be close to completion of their degree.

Benefits include generous maternity/paternity leave, flexible working, funds for returning carers and other family-friendly schemes.

Limited funding: The funds for this post are available for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please upload a CV, a brief statement of your research interests and cover letter with your application.

Please contact Nikki Mann if you require further information at jobs@gurdon.cam.ac.uk or telephone 01223 334088.

Please quote reference PR05951 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate

From Jobs at the University of Cambridge. Published on Apr 23, 2015.

A Research Associate is being sought to work on a project on "Machine learning for hearing aids: Intelligent processing and fitting", funded by the Engineering and Physical Sciences Research Council. This is a 3-year fixed-term position. The project involves a collaboration between Dr. Richard Turner (Engineering) and Professor Brian C.J. Moore (Psychology). The Research Associate will be based in the laboratory of Professor Moore but will frequently visit the laboratory of Dr. Turner. Both laboratories are located in central Cambridge.

Applicants should have a Ph.D. in psychoacoustics, audiology, hearing science, audio engineering, signal processing, or a closely related discipline. The work involves the development of auditory models, including models of hearing loss, and the use of those models to guide characterization of the impaired auditory system and fitting of hearing aids. The work also involves setting up listening tests, recruiting and testing hearing-impaired participants, analysing the results, and contributing to the writing of papers for publication.

The following skills and experience are desirable: programming skills, especially in Matlab; experience in running psychoacoustic and speech perception tests; experience in auditory modeling; familiarity with hearing aids and the fitting of hearing aids; ability to interact well with experimental participants and be sympathetic to the needs of older hearing-impaired participants; ability to perform statistical analyses and prepare figures.

The starting date for the position is 1st October, 2015. The position will last for 3 years and is not renewable.

Further information may be downloaded below.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Please quote reference PJ05947 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Clinician Scientists

From Jobs at the University of Cambridge. Published on Apr 15, 2015.

The Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute is founded on the belief that deep understanding of stem cell biology will be transformative for future healthcare (http://www.stemcells.cam.ac.uk).

The Institute is seeking clinician scientists to complement our existing programmes and contribute to translating advances in stem cell science into better management of disease and new regenerative medicines. Applications in any area of medicine or surgery are welcome.

Applicants should have completed a higher degree and be (or have recently been) clinically active either at a junior (specialist trainee) or senior level (post-clinical training). In addition to a medical qualification and award of a PhD or equivalent research training, junior candidates will have preferably a minimum of 1 year post-doctoral experience, original research achievements, and an exceptional project proposal. Senior candidates should have an established track record as an independent group leader engaged in high quality science and have an outstanding and well-founded research proposal.

The Institute offers a collegiate environment with both excellent core facilities for laboratory-based studies (stem cell culture, transgenesis, flow cytometry, complex microscopy and bioinformatics) and extensive opportunities to pursue patient based studies. Successful candidates will be supported to obtain external personal fellowship and grant support within 1-2 years. Start-up packages are available according to circumstances. The institute would seek to facilitate interaction between the post holder and the appropriate clinical services in Cambridge University Hospitals NHS Foundation Trust or the Training Deanery depending on seniority.

Your salary will be dependent on your honorary clinical contract status with the relevant NHS Trust and seniority. Salary range £31,301-£101,451.

You can find the SCI Review 2014 on our website, at http://www.stemcells.cam.ac.uk/about-us/brochure/.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applicants should upload a full curriculum vitae with contact details of 3 referees, and 1-2 page outline of research interests, by Monday 1st June 2015.

Informal enquiries can be made to Prof. Robin Franklin (rjf1000@cam.ac.uk) or Prof. Tony Green (arg1000@cam.ac.uk).

Interviews will be held on 28th and 29th July 2015.

Please quote reference PS05814 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

University Lecturer

From Jobs at the University of Cambridge. Published on Mar 26, 2015.

Applications are invited for a research-oriented, tenure-track University Lectureship in Physiology, available from 1 November 2015 or as soon as possible thereafter. Based in central Cambridge, we are searching for an outstanding scientist, with an excellent publication record, undertaking cutting edge and fundable work in a field which complements our world class programme in physiology with a preference for comparative physiology or mammalian systems physiology research (http://www.pdn.cam.ac.uk/research/).

The successful applicant will have a PhD in a relevant subject area, will have an aptitude and enthusiasm for teaching, and be willing to contribute effectively to our undergraduate programmes in preclinical medicine, preclinical veterinary science, and natural sciences (http://www.pdn.cam.ac.uk/teaching). He/she will be expected to contribute to the design and delivery of undergraduate and graduate lecture courses and to perform other academic duties including administration, examining and assessment.

We welcome applications from all qualified candidates and we strongly encourage women to apply. Appointment will be based on merit alone.

Informal enquiries may be made to Professor Bill Harris, Head of Department (wah20@cam.ac.uk; +44 (0) 1223 766137/333772).

Appointment will be made at University Lecturer level with a probationary period of five years, with appointment to the retirement age thereafter. The pensionable salary scale starts at £38,511 to £48,743 per annum. Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment, with a satisfactory outcome determined by the University.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that, in the Upload section of the online application, you upload your Curriculum Vitae (CV), a research publication list which highlights your three most important published outputs, and a covering letter of no more than two pages, outlining current and future plans, indicating the fit within the research profile of the Department and how you might contribute to our teaching. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Closing Date: 30 June 2015

Please quote reference PM05747 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Career Development Fellow

From Jobs at the University of Cambridge. Published on Feb 09, 2015.

Applications are invited for Research Career Development Fellowships in the Sainsbury Laboratory. The positions are open to applicants of any nationality. With the intention of nurturing the next generation of researchers in the field of plant science, the Fellowships provide an opportunity for talented junior investigators to develop their own research programme and become creative leaders in the field.

The Sainsbury Laboratory is a new Research Institute located in central Cambridge, providing an outstanding scientific environment. It has excellent resources and core facilities, with state-of-the-art equipment including growth rooms, glasshouses, microscopy and computing facilities. It provides a collaborative research atmosphere where researchers can take risks in a supportive environment. We are seeking to appoint Career Development Fellows who can both contribute to and benefit from this environment. In particular we are looking for scientists with imaginative research ideas that will contribute to our understanding of plant development, by elucidating the links between genotype and phenotype in any appropriate study system.

Applicants will typically have between 3 and 6 years of postdoctoral experience in a field related to the overall scientific focus of the Laboratory in plant development and its computational modelling. Applicants should be able to provide strong evidence of their potential to develop independent research programmes.

Fellowships are for five years. Successful applicants will receive an initial three years of funding, with extension for a further two years contingent on a successful scientific review and will hold an appointment with the University of Cambridge. Funds include full salary, ranging from £38,511 to £48,743, an additional 30% Gatsby distinction award, benefits and £40,000 p.a. of unrestricted research support. As they develop into independent researchers, Fellows will be encouraged to apply for external funding. Fellows can apply for Research Group Leader positions within the Laboratory at any time.

Further details about the post, guidance on how to apply and information about the Sainsbury Laboratory are available on the Sainsbury Laboratory web site: http://www.slcu.cam.ac.uk/

Applications can be submitted electronically at any time as a single pdf file including a full CV, a research proposal for five years, and the names of at least three referees. Completed applications should be sent by e-mail to enquiries@slcu.cam.ac.uk.

Fixed-term: The funds for this post are available for 5 years.

There is no fixed closing date- applications will be assessed throughout the year.

Please quote reference PT05330 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Career Development Fellow - Computational Modelling of Developmental Systems

From Jobs at the University of Cambridge. Published on Feb 09, 2015.

Applications are invited for Research Career Development Fellowships in the Sainsbury Laboratory. The positions are open to applicants of any nationality. With the intention of nurturing the next generation of interdisciplinary researchers in the field of plant developmental biology, the Fellowships provide an opportunity for talented junior investigators to develop their own research program and become creative leaders in the field. The Sainsbury Laboratory is a new Research Institute, providing an outstanding scientific environment. It has excellent resources and core facilities, with state-of-the-art equipment including high performance computing, growth rooms, glasshouses and microscopy. It provides a collaborative research atmosphere where researchers can take risks in a supportive environment. We are seeking to appoint Career Development Fellows who can both contribute to and benefit from this environment. In particular we are looking for scientists with computational or mathematical modeling expertise and imaginative research ideas that will contribute to our understanding of plant development by elucidating the links between genotype and phenotype. Experience with plant systems is not required. Applications are welcome from researchers wishing to move into plant biology from any other study system.

Applicants will typically have between 3 and 6 years of postdoctoral experience and should be able to provide strong evidence of their potential to develop independent research programs. Fellowships are for five years. Successful applicants will receive an initial three years of funding, with extension for a further two years contingent on a successful scientific review and will hold an appointment with the University of Cambridge. Funds include full salary, ranging from £38,511 to £48,743, an additional 30% Gatsby distinction award, benefits and £40,000 p.a. of unrestricted research support. As they develop into independent researchers, Fellows will be encouraged to apply for external funding. Fellows can apply for Research Group Leader positions within the Laboratory at any time.

Further details about the post, guidance on how to apply and information about the Sainsbury Laboratory are available on the Sainsbury Laboratory web site: http://www.slcu.cam.ac.uk/

Applications can be submitted electronically at any time as a single pdf file including a full CV, a research proposal for five years, and the names of at least three referees. Completed applications should be sent by e-mail to enquiries@slcu.cam.ac.uk.

Fixed-term: The funds for this post are available for 5 years.

There is no fixed closing date - applications will be assessed throughout the year.

Please quote reference PT05341 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.